Mass General Brigham, Inc — 13F Holdings & Portfolio

CIK 1678378 · latest 13F-HR filed 2026-05-05

Mass General Brigham, Inc manages $468.9M in 13F-reported U.S. long-equity assets across 6 reported positions as of its 2026-03-31 13F-HR filing. Its largest disclosed positions are ACWI (62.42%), KRMN (26.67%), RVMD (7.14%). Quarter over quarter (versus its 2025-12-31 filing) the fund opened 0 new positions, exited 1, added to 4, and trimmed 2.

AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.

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AUM

$468.9M

Long-equity book

Holdings

6

Distinct positions

Period

2026-03-31

Filed 2026-05-05

Q/Q Activity

+0 / −1 / ↑4 / ↓2

vs 2025-12-31

Firm Profile & Key People
Name Title / Status Ownership Type

Top Adds (vs prior quarter)

  • KARMAN HLDGS INC$10.7M +9.4%
  • REVOLUTION MEDICINES INC$6.1M +22.1%
  • TANGO THERAPEUTICS INC$4.3M +136.1%
  • MEDLINE INC$2.0M +183.5%
Show all 4

Top Trims

  • ISHARES TR-$360.1M -55.2%
  • MAZE THERAPEUTICS INC-$2.8M -28.0%
Show all 2

New Positions

  • No new positions this quarter.
Show all 0

Exited Positions

  • RUBRIK INC$1.1M
Show all 1
All Holdings

Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).

# Issuer Symbol CUSIP Value Weight Shares Type
1 ISHARES TR ACWI 464288257 $292.7M 62.42% 2,153,477 SH
2 KARMAN HLDGS INC KRMN 485924104 $125.0M 26.67% 1,562,054 SH
3 REVOLUTION MEDICINES INC RVMD 76155X100 $33.5M 7.14% 344,091 SH
4 TANGO THERAPEUTICS INC TNGX 87583X109 $7.4M 1.58% 354,192 SH
5 MAZE THERAPEUTICS INC MAZE 578784100 $7.2M 1.53% 239,994 SH
6 MEDLINE INC MDLN 58507V107 $3.1M 0.67% 70,357 SH
Filing History
Period Filed AUM Holdings Accession
2026-03-31 2026-05-05 $468.9M 6 0001214659-26-005558
2025-12-31 2026-01-27 $809.8M 7 0001214659-26-000882