SYROS PHARMACEUTICALS INC(SYRS)

Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership.

SYRS iron condor setups SYRS expected move SYRS IV rank history

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.

Snapshot
$0.02
52-Week Range
$0.00 – $0.04
YTD
+11800.00%
IV Rank (30D)
0
Straddle Price
$0.00
P/C Vol Ratio
0.08
Info
Exchange
OTC Link
Price History
Seasonality
MonthAvg ReturnYears of Data
Jan +2.79% 10
Feb -16.13% 10
Mar -3.05% 10
Apr +2.88% 10
May +2.14% 10
Jun +3.13% 11
Jul -11.19% 10
Aug +11.73% 10
Sep -15.47% 10
Oct -19.94% 10
Nov -11.26% 10
Dec +8.45% 10
Technical Indicators

Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.

Trend Indicators
  • SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
  • EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
  • MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
  • ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
  • +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
  • RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
  • Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
  • Williams %R — inverted scale: <−80 oversold, >−20 overbought.

Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.

Volume & Volatility
  • Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
  • OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
  • Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
  • ATR / True Range — average daily $ move; sizing and stop-loss reference.
  • HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.

Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →

Trend Indicators
SMA 20: $0.00
SMA 50: $0.00
SMA 200: $0.00
Current: $0.00
EMA 12: $0.00
EMA 26: $0.00
MACD: 0.0000 | Signal: 0.0000
BEARISH
ADX (14): 89.34
STRONG TREND
+DI: 66.76
−DI: 3.81
Momentum Oscillators
RSI (14): 55.03
NEUTRAL
Stoch %K: 44.44
Stoch %D: 29.63
Williams %R: -33.33
Volume & Volatility
BB Upper: $0.00
BB Lower: $0.00
NEUTRAL
OBV: 1,416,406,303
Vol SMA 20: 12,390
Vol ROC: -28.46%
ATR: $0.00
True Range: $0.00
HV 20: 714.0%
HV 30: 801.2%
HV 60: 816.4%
Data Summary
Data Points: 500
Last Updated: 2026-06-12T21:15:19.769000
Date Range: 2024-06-04T00:00:00 – 2026-06-05T00:00:00
AI Analysis

Choose Frenzy-Fast™ for quick analysis or Frenzy-Pro™ for comprehensive analysis.

Analysis includes technical indicators, news sentiment, risk assessment, and specific price levels to watch.

News
Options Activity
IV Rank (30D)
0
IV Rank (7D)
0
Avg IV
0.0%
Straddle (30D)
$0.00
Straddle (7D)
$0.00
P/C Volume
0.08
Spread Scanner GPU
Full Algorithm Docs ↗

Each spread is ranked by a composite score built in three stages. Full documentation →

Stage 1 — Base Score (GPU scanner)

score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.

Stage 2 — Skew Adjustment (±25% cap)

RR25 and BF25 from the live options chain. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.

Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
  • RSI <40 bullish / >60 bearish
  • MACD crossover + histogram trend
  • Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
  • Stochastic %K <20 / >80
  • Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
  • Blended ATR + straddle expected-move penalty
  • Bollinger Band signal (+ counter-trend penalty)
  • BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
  • IV rank ≥ 75 → strong boost for credit spreads
  • IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
  • Min open interest across all legs
  • OI < 100 → −0.10 · OI < 500 → −0.05

score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →

Enter a ticker to scan for optimal spread opportunities.

Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.

Volatility Surface

Enter a ticker to render the implied volatility surface.

IV Rank (7 DTE)
IV Rank (30 DTE)
Straddle Price (30 DTE)
Beta Analysis
Beta (1Y vs SPY)
2.26
Correlation (SPY)
0.5%
R²
0.00
Ann. Volatility
6064.0%
SPY Volatility
12.1%

High volatility - stock moves more than market

Beta & Alpha Over Time
Institutional Ownership (13F)

Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.

  • Shares — long equity positions in this name, aggregated across share classes.
  • Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
  • % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
  • Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.

Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.

# Filer Shares Value % of Total % of Float Period
# Filer Notional Value % of Total Period
# Filer Notional Value % of Total Period
Insider Activity
Latest: 2024-12-04
Form 4 filings — insider beneficial-ownership changes by officers, directors, and 10%+ holders. Filed within 2 business days of transaction.
Filed Reporter Role Action Shares Avg Price Net $ Link
2024-12-04 Nancy A Simonian Director Sell (S) −37,070 $0.27 -$10.0K EDGAR
2024-11-27 Nancy A Simonian Director Sell (S) −134,713 $0.27 -$35.7K EDGAR
2024-11-20 Jason Haas Chief Financial Officer Sell (S) −137,803 $0.21 -$29.0K EDGAR
2024-11-20 Gerald E Quirk Chief Legal & Compliance Offic Sell (S) −46,657 $0.22 -$10.3K EDGAR
2024-11-20 Conley Chee President & CEO Sell (S) −134,797 $0.20 -$26.9K EDGAR
2024-11-20 Kristin Stephens Chief Development Officer Sell (S) −36,133 $0.22 -$7.9K EDGAR
2024-11-20 David Roth Chief Medical Officer Sell (S) −12,099 $0.20 -$2.4K EDGAR
2024-11-04 Conley Chee President & CEO Mixed +8,293 $2.09 -$18.2K EDGAR
2024-11-04 Kristin Stephens Chief Development Officer Mixed +10,896 $2.09 -$12.8K EDGAR
2024-11-04 Jason Haas Chief Financial Officer Mixed +13,251 $2.09 -$11.8K EDGAR
2024-11-04 David Roth Chief Medical Officer Mixed +12,099 $2.09 -$14.2K EDGAR
2024-11-04 Nancy A Simonian Director Exer (M) +40,125 — EDGAR
2024-10-02 Gerald E Quirk Chief Legal & Compliance Offic Mixed +6,900 $2.10 -$6.5K EDGAR
2024-09-18 SRINIVAS AKKARAJU Director Exer (M) +2,667 — EDGAR
2024-09-18 Richard A Young Director Exer (M) +2,667 — EDGAR
Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (described in filing footnote — typically 401(k), trust, inheritance) · W = will/inheritance. Only P / S codes carry directional signal.
Insider Holdings
29 insiders · @ $0.00
Officers, directors, and 10%+ owners ranked by current disclosed exposure (shares × today's price). Shares are direct + indirect (via trusts / LLCs / spouse). Excludes unvested RSU and option grants — those aren't beneficially owned until vest.
# Insider Role Shares Disclosed Exposure Lifetime OM Net Filings Last Filed
1 ROBERT NELSEN Director 4,637,137 $1.9K $5.00M 4 2017-09-22
2 ARCH Venture Fund VII, L.P. 10%+ Owner 4,637,137 $1.9K $25.00M 1 2016-07-07
3 KEITH CRANDELL 10%+ Owner 4,350,871 $1.7K -$14.59M 2 2019-03-14
4 CLINTON BYBEE 10%+ Owner 4,302,051 $1.7K -$2.94M 1 2019-07-17
5 Flagship VentureLabs IV, LLC 10%+ Owner 2,991,105 $1.2K $0 1 2017-08-21
6 SRINIVAS AKKARAJU Director 1,795,760 $718 $7.14M 22 2024-09-18
7 Polaris Management Co. VII, L.L.C. 10%+ Owner 1,164,486 $466 $15.00M 1 2016-07-07
8 Aisling Capital Partners III LP 10%+ Owner 908,565 $363 $30.00M 1 2016-07-06
9 Flagship Ventures Fund IV-Rx, L.P. 10%+ Owner 838,664 $335 $30.00M 1 2016-07-07
10 DEERFIELD MANAGEMENT COMPANY, L.P. 10%+ Owner 628,566 $251 $30.00M 1 2016-07-06
11 WuXi Healthcare Ventures II, L.P. 10%+ Owner 423,805 $170 $0 1 2016-07-06
12 WuXi PharmTech Healthcare Fund I L.P. 10%+ Owner 399,999 $160 $0 1 2016-07-07
13 PHILLIP A SHARP Director 186,666 $75 $0 9 2022-06-02
14 Joseph J Jr Ferra Chief Financial Officer 87,000 $35 $0 4 2021-02-19
15 Jeremy Green 10%+ Owner 84,760 $34 $10.82M 1 2016-07-07
16 Nancy A Simonian Director 84,000 $34 -$45.8K 22 2024-12-04
17 Stephane Bancel Director 47,980 $19 $0 2 2016-09-19
18 TIMOTHY TYSON Director 33,189 $13 $106.0K 5 2024-06-07
19 Jeremy P. Springhorn Chief Business Officer 24,879 $10 $235.9K 6 2021-02-19
20 Amir Nashat Director 22,167 $9 $5.00M 9 2022-06-02
21 ANDREW M. OH Director 16,000 $6 $0 3 2024-06-07
22 Sue Gail Eckhardt Director 16,000 $6 $0 6 2024-06-07
23 Marsha Fanucci Director 16,000 $6 $0 11 2024-06-07
24 PETER WIRTH Director 16,000 $6 $0 9 2024-06-07
25 Deborah Dunsire Director 12,000 $5 $0 6 2024-06-07
26 Richard A Young Director 10,667 $4 -$1.35M 29 2024-09-18
27 Eric R Olson Chief Scientific Officer 6,661 $3 -$619.0K 19 2023-07-18
28 Mark J Alles Director 3,666 $1 $88.6K 8 2023-09-19
29 Colleen Elizabeth DeSimone Principal Accounting Officer 550 $0 -$8.8K 1 2017-10-23
Lifetime OM Net = signed sum of open-market buys (P) and sells (S) over their career; excludes grants, tax withholdings, and dispositions to issuer. A large negative number is normal for long-tenured executives — they've sold compensation grants over many years.
ETF Holders
# ETF Provider Weight $ Exposure ETF AUM As Of
Fundamentals

Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.

Metrics
  • Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
  • Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
  • Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
  • Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
How to read the bars
  • Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
  • YoY growth — compare to the same quarter a year earlier to remove seasonality.
  • Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
  • Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.

TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.