ORACLE INVESTMENT MANAGEMENT INC — 13F Holdings & Portfolio
CIK 1012622 · latest 13F-HR filed 2026-02-18
ORACLE INVESTMENT MANAGEMENT INC manages $167.9M in 13F-reported U.S. long-equity assets across 22 reported positions as of its 2025-12-31 13F-HR filing. Its largest disclosed positions are WGS (68.51%), ARDX (6.50%), BHVN (5.19%). Quarter over quarter (versus its 2025-09-30 filing) the fund opened 6 new positions, exited 5, added to 4, and trimmed 4.
AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.
$167.9M
Long-equity book
22
Distinct positions
2025-12-31
Filed 2026-02-18
+6 / −5 / ↑4 / ↓4
vs 2025-09-30
| Name | Title / Status | Ownership | Type |
|---|
Top Adds (vs prior quarter)
- GENEDX HOLDINGS CORP$19.2M +20.0%
- ARDELYX INC$2.6M +31.8%
- PERSONALIS INC$1.2M +80.6%
- BIOGEN INC$86.6K +25.6%
Top Trims
- TELADOC HEALTH INC-$3.0M -54.5%
- BIOHAVEN LTD-$2.4M -21.5%
- SANGAMO THERAPEUTICS INC-$241.6K -35.7%
- FORIAN INC-$177.6K -5.8%
New Positions
- TAYSHA GENE THERAPIES INC$1.5M
- EDGEWISE THERAPEUTICS INC$951.5K
- DAY ONE BIOPHARMACEUTICALS I$932.0K
- ARK ETF TR$564.9K
- TEMPUS AI INC$384.2K
Exited Positions
- PALANTIR TECHNOLOGIES INC$5.4M
- CENTENE CORP DEL$3.9M
- NOVAVAX INC$2.1M
- KRANESHARES TRUST$718.6K
- BIODESIX INC$113.2K
Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).
| # | Issuer | Symbol | CUSIP | Value | Weight | Shares | Type |
|---|---|---|---|---|---|---|---|
| 1 | GENEDX HOLDINGS CORP | WGS | 81663L200 | $115.1M | 68.51% | 884,654 | SH |
| 2 | ARDELYX INC | ARDX | 039697107 | $10.9M | 6.50% | 1,872,624 | SH |
| 3 | BIOHAVEN LTD | BHVN | G1110E107 | $8.7M | 5.19% | 772,181 | SH |
| 4 | TELADOC HEALTH INC Call | TDOC | 87918A905 | $4.5M | 2.71% | 650,000 | SH |
| 5 | NOVAVAX INC Call | NVAX | 670002AD6 | $4.0M | 2.40% | 600,000 | PRN |
| 6 | ARDELYX INC Call | ARDX | 039697907 | $3.5M | 2.08% | 600,000 | SH |
| 7 | QUIDELORTHO CORP | QDEL | 219798105 | $3.4M | 2.01% | 118,291 | SH |
| 8 | FORIAN INC | FORA | 34630N106 | $2.9M | 1.72% | 1,366,107 | SH |
| 9 | PERSONALIS INC | PSNL | 71535D106 | $2.7M | 1.61% | 339,343 | SH |
| 10 | BIOHAVEN LTD Call | BHVN | G1110E907 | $2.6M | 1.57% | 232,900 | SH |
| 11 | TELADOC HEALTH INC | TDOC | 87918A105 | $2.5M | 1.48% | 354,338 | SH |
| 12 | TAYSHA GENE THERAPIES INC | TSHA | 877619106 | $1.5M | 0.87% | 265,000 | SH |
| 13 | CAVA GROUP INC | CAVA | 148929102 | $1.0M | 0.60% | 17,100 | SH |
| 14 | EDGEWISE THERAPEUTICS INC | EWTX | 28036F105 | $951.5K | 0.57% | 38,343 | SH |
| 15 | DAY ONE BIOPHARMACEUTICALS I | DAWN | 23954D109 | $932.0K | 0.55% | 100,000 | SH |
| 16 | PFIZER INC Call | PFE | 717081903 | $622.5K | 0.37% | 25,000 | SH |
| 17 | ARK ETF TR | ARKG | 00214Q302 | $564.9K | 0.34% | 19,500 | SH |
| 18 | SANGAMO THERAPEUTICS INC | SGMO | 800677106 | $435.0K | 0.26% | 1,035,742 | SH |
| 19 | BIOGEN INC | BIIB | 09062X103 | $424.5K | 0.25% | 2,412 | SH |
| 20 | TEMPUS AI INC | TEM | 88023B103 | $384.2K | 0.23% | 6,507 | SH |
| 21 | TESLA INC | TSLA | 88160R101 | $224.9K | 0.13% | 500 | SH |
| 22 | HERTZ GLOBAL HLDGS INC | HTZ | 42806J700 | $77.1K | 0.05% | 15,000 | SH |
| Period | Filed | AUM | Holdings | Accession |
|---|---|---|---|---|
| 2025-12-31 | 2026-02-18 | $167.9M | 22 | 0001012622-26-000001 |
| 2025-09-30 | 2025-11-19 | $160.1M | 20 | 0001012622-25-000003 |