Inozyme Pharma, Inc. Common Stock(INZY)

Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership.

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.

Snapshot
$4.00
52-Week Range
$3.97 – $4.00
IV Rank (30D)
72.0
Straddle Price
$0.00
P/C Vol Ratio
0.19
Market Cap
$0.3B
Info
Industry (SIC)
PHARMACEUTICAL PREPARATIONS (2834)
Exchange
XNAS
Market Cap
$0.3B

Inozyme Pharma Inc is a clinical-stage biopharmaceutical company developing novel therapeutics for the treatment of diseases impacting bone health and blood vessel function. The company is focused on developing a novel therapy to treat the rare genetic diseases of ENPP1 and ABCC6 deficiencies. Its product candidate, INZ-701, is a soluble, recombinant, genetically engineered fusion protein that is designed to correct a defect in a pathway involving ENPP1 and ABCC6 deficiencies.

Price History
Seasonality
MonthAvg ReturnYears of Data
Jan +14.67% 5
Feb +1.33% 5
Mar +12.79% 5
Apr -5.81% 5
May +54.62% 5
Jun +2.95% 5
Jul +0.18% 4
Aug -4.59% 4
Sep -15.11% 4
Oct -14.12% 4
Nov -10.65% 4
Dec -4.61% 4
Technical Indicators

Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.

Trend Indicators
  • SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
  • EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
  • MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
  • ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
  • +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
  • RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
  • Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
  • Williams %R — inverted scale: <−80 oversold, >−20 overbought.

Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.

Volume & Volatility
  • Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
  • OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
  • Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
  • ATR / True Range — average daily $ move; sizing and stop-loss reference.
  • HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.

Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →

Trend Indicators
SMA 20: $3.99
SMA 50: $2.85
SMA 200: $2.79
Current: $4.00
EMA 12: $3.97
EMA 26: $3.70
MACD: 0.2671 | Signal: -0.0887
BULLISH
ADX (14): 73.15
STRONG TREND
+DI: 53.00
−DI: 6.54
Momentum Oscillators
RSI (14): 82.70
OVERBOUGHT
Stoch %K: 88.89
Stoch %D: 81.48
Williams %R: 0.00
Volume & Volatility
BB Upper: $4.00
BB Lower: $3.97
NEUTRAL
OBV: 49,070,872
Vol SMA 20: 1,079,382
Vol ROC: 237.29%
ATR: $0.05
True Range: $0.01
HV 20: 3.5%
HV 30: 296.4%
HV 60: 232.4%

Data Summary
Data Points: 500
Last Updated: 2026-06-12T21:15:18.384000
Date Range: 2023-07-03T00:00:00 – 2025-06-30T00:00:00
AI Analysis

Choose Frenzy-Fast™ for quick analysis or Frenzy-Pro™ for comprehensive analysis.

Analysis includes technical indicators, news sentiment, risk assessment, and specific price levels to watch.

News
Earnings History
4 of 4 under expected move
Each row pairs the pre-earnings straddle-implied expected move with the realized close-to-close move. Sorted oldest first.
Earnings Date Timing Expected Move Actual Move Ratio Outcome
2024-08-06 After-Close 18.88% 9.59% 0.51x Within
2024-11-05 After-Close 30.70% 6.02% 0.20x Within
2025-01-10 After-Close 48.08% 14.35% 0.30x Within
2025-03-10 After-Close 78.83% 2.71% 0.03x Within
Options Activity
IV Rank (30D)
72.0
IV Rank (7D)
72.0
Avg IV
760.0%
Straddle (30D)
$0.00
Straddle (7D)
$0.00
P/C Volume
0.19
Spread Scanner GPU

Each spread is ranked by a composite score built in three stages. Full documentation →

Stage 1 — Base Score (GPU scanner)

score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.

Stage 2 — Skew Adjustment (±25% cap)

RR25 and BF25 from the live options chain. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.

Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
  • RSI <40 bullish / >60 bearish
  • MACD crossover + histogram trend
  • Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
  • Stochastic %K <20 / >80
  • Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
  • Blended ATR + straddle expected-move penalty
  • Bollinger Band signal (+ counter-trend penalty)
  • BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
  • IV rank ≥ 75 → strong boost for credit spreads
  • IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
  • Min open interest across all legs
  • OI < 100 → −0.10 · OI < 500 → −0.05

score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →

Enter a ticker to scan for optimal spread opportunities.

Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.

Volatility Surface

Enter a ticker to render the implied volatility surface.

IV Rank (7 DTE)
IV Rank (30 DTE)
Straddle Price (30 DTE)
Beta Analysis
Beta & Alpha Over Time
Institutional Ownership (13F)

Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.

  • Shares — long equity positions in this name, aggregated across share classes.
  • Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
  • % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
  • Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.

Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.

# Filer Shares Value % of Total % of Float Period
# Filer Notional Value % of Total Period
# Filer Notional Value % of Total Period
Insider Activity
Latest: 2025-06-27
Form 4 filings — insider beneficial-ownership changes by officers, directors, and 10%+ holders. Filed within 2 business days of transaction.
Filed Reporter Role Action Shares Avg Price Net $ Link
2025-06-27 Matthew Winton COO Award (A) +14,355 $0.74 $10.6K EDGAR
2025-06-27 Douglas A Treco CEO & Chairman Award (A) +2,815 $0.74 $2.1K EDGAR
2025-06-27 Sanjay Subramanian SVP, CFO & Head of BD Award (A) +6,813 $0.74 $5.0K EDGAR
2025-05-20 Axel Bolte Director Exer (M) +157,230 $0.98 $154.1K EDGAR
2025-04-03 Douglas A Treco CEO & Chairman Mixed +16,181 $0.89 -$7.8K EDGAR
2025-04-02 Matthew Winton COO Award (A) +2,490 $0.77 $1.9K EDGAR
2025-04-02 Sanjay Subramanian SVP, CFO & Head of BD Award (A) +2,490 $0.77 $1.9K EDGAR
2025-03-17 Matthew Winton COO Grant (A) +186,500 opt EDGAR
2025-03-17 Sanjay Subramanian SVP, CFO Grant (A) +183,500 opt EDGAR
2025-03-17 Douglas A Treco CEO Grant (A) +500,000 RSU EDGAR
2024-10-07 Erik Harris Director Grant (A) +56,000 opt EDGAR
2024-10-03 Matthew Winton COO Award (A) +1,710 $4.45 $7.6K EDGAR
2024-10-03 Douglas A Treco CEO Award (A) +1,710 $4.45 $7.6K EDGAR
2024-06-20 Robert Lorne Hopfner Director Grant (A) +28,000 opt EDGAR
2024-06-20 Martin Edwards Director Grant (A) +28,000 opt EDGAR
Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (described in filing footnote — typically 401(k), trust, inheritance) · W = will/inheritance. Only P / S codes carry directional signal.
Insider Holdings
24 insiders · @ $4.00
Officers, directors, and 10%+ owners ranked by current disclosed exposure (shares × today's price). Shares are direct + indirect (via trusts / LLCs / spouse). Excludes unvested RSU and option grants — those aren't beneficially owned until vest.
# Insider Role Shares Disclosed Exposure Lifetime OM Net Filings Last Filed
1 Longitude Venture Partners III, L.P. 10%+ Owner 4,174,379 $16.70M $20.00M 1 2022-04-21
2 Robert Lorne Hopfner Director 2,923,110 $11.69M $16.20M 11 2024-06-20
3 NEA 15 GP, LLC 10%+ Owner 2,437,689 $9.75M $12.00M 1 2020-07-28
4 Mohamad Makhzoumi 10%+ Owner 2,437,689 $9.75M $4.00M 1 2020-07-28
5 Novo Holdings A/S 10%+ Owner 2,194,379 $8.78M -$1.88M 2 2021-02-01
6 SCOTT D SANDELL 10%+ Owner 2,187,689 $8.75M $4.00M 1 2020-07-28
7 Peter W. Sonsini 10%+ Owner 2,187,689 $8.75M $4.00M 1 2020-07-28
8 PATRICK G ENRIGHT 10%+ Owner 2,007,225 $8.03M $40.00M 1 2020-07-28
9 JOSHUA MAKOWER 10%+ Owner 2,000,533 $8.00M $4.00M 1 2020-07-28
10 FOREST BASKETT 10%+ Owner 2,000,533 $8.00M $4.00M 1 2020-07-28
11 Anthony A. Jr. Florence 10%+ Owner 2,000,533 $8.00M $4.00M 1 2020-07-28
12 Maha Katabi 10%+ Owner 1,590,808 $6.36M $35.00M 1 2020-07-28
13 Pivotal bioVenture Partners Fund I U.G.P. Ltd Director 1,571,741 $6.29M $32.84M 3 2023-08-03
14 Rajeev M. Shah 10%+ Owner 1,403,653 $5.61M $28.80M 1 2020-07-28
15 ALEXION PHARMACEUTICALS, INC. 10%+ Owner 1,109,910 $4.44M $0 1 2020-07-28
16 Rock Springs Capital LLC 10%+ Owner 467,884 $1.87M $28.80M 1 2020-07-28
17 Sanofi 10%+ Owner 438,875 $1.76M $1.30M 1 2020-07-29
18 Axel Bolte Director 423,926 $1.70M $250.0K 12 2025-05-20
19 Joseph Schlessinger 10%+ Owner 286,479 $1.15M $0 1 2020-07-28
20 Henric Bjorn Bjarke SVP, COO 105,441 $421.8K $129.9K 7 2022-12-19
21 Steven J Jungles SVP, CTO 55,417 $221.7K $0 3 2021-03-17
22 Douglas A Treco CEO & Chairman 43,861 $175.4K -$60.1K 10 2025-06-27
23 Sanjay Subramanian SVP, CFO & Head of BD 39,701 $158.8K $100.0K 9 2025-06-27
24 Matthew Winton COO 21,743 $87.0K $0 7 2025-06-27
Lifetime OM Net = signed sum of open-market buys (P) and sells (S) over their career; excludes grants, tax withholdings, and dispositions to issuer. A large negative number is normal for long-tenured executives — they've sold compensation grants over many years.
ETF Holders
# ETF Provider Weight $ Exposure ETF AUM As Of
Fundamentals

Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.

Metrics
  • Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
  • Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
  • Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
  • Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
How to read the bars
  • Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
  • YoY growth — compare to the same quarter a year earlier to remove seasonality.
  • Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
  • Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.

TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.