iShares Neuroscience and Healthcare ETF(IBRN · ETF)

ETF quote, holdings, sector allocation, technicals, and options analytics.

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.

Snapshot
$34.91
52-Week Range
$21.78 – $37.00
YTD
+9.83%
IV Rank (30D)
41.25
Straddle Price
$2.60
Info

iShares Neuroscience and Healthcare ETF (IBRN) ETF

Exchange
ARCX
Inception
2022-08-24
Has Options
Yes
ETF Profile
holdings as of 2026-07-31
Holdings
68
AUM
$4.9M
Provider
iShares (BlackRock)
Inception
2022-08-24
Exchange
ARCX
Data As Of
2026-07-31
Expense Ratio
Dividend Yield
0.92%
Distribution
Semi-Annual
Recent distributions
Ex-Date Pay Date Amount Type
2025-12-16 2025-12-19 $0.3198 CD
2024-12-17 2024-12-20 $0.1011 CD
2023-12-20 2023-12-27 $0.0063 CD
2023-06-07 2023-06-13 $0.0082 CD
Asset Allocation
Top Holdings
top 50 of 68 holdings
Symbol Name Weight % Asset Class Country
BlackRock Funds III: BlackRock Cash Funds: Institutional; SL Agency Shares 13.30% Short-term investment US
PRAX Praxis Precision Medicines Inc 5.02% Equity (common) US
AXSM AXSOME THERAPEUTICS, INC. 4.90% Equity (common) US
ALKS ALKERMES PUBLIC LIMITED COMPANY 4.55% Equity (common) IE
BIIB BIOGEN INC. 3.93% Equity (common) US
SRRK Scholar Rock Holding Corp 3.91% Equity (common) US
PTCT PTC THERAPEUTICS, INC. 3.88% Equity (common) US
DNLI Denali Therapeutics Inc 3.71% Equity (common) US
argenx SE 3.70% Other NL
ACAD ACADIA PHARMACEUTICALS INC. 3.63% Equity (common) US
XENE Xenon Pharmaceuticals Inc 3.61% Equity (common) CA
CPRX CATALYST PHARMACEUTICALS, INC. 3.53% Equity (common) US
NBIX NEUROCRINE BIOSCIENCES, INC. 3.47% Equity (common) US
SUPN SUPERNUS PHARMACEUTICALS, INC. 3.44% Equity (common) US
CENTESSA PHARMACEUTICALS PLC 3.10% Other GB
SK Biopharmaceuticals Co Ltd 3.01% Equity (common) KR
EWTX Edgewise Therapeutics Inc 2.82% Equity (common) US
AVDL AVADEL PHARMACEUTICALS PUBLIC LIMITED COMPANY 2.64% Equity (common) IE
SRPT SAREPTA THERAPEUTICS, INC. 2.64% Equity (common) US
DYN Dyne Therapeutics Inc 2.46% Equity (common) US
DNTH Dianthus Therapeutics Inc 2.46% Equity (common) US
H. LUNDBECK A/S 2.35% Equity (common) DK
AXGN AxoGen, Inc. 2.06% Equity (common) US
BioArctic AB 1.82% Equity (common) SE
BHVN Biohaven Ltd 1.68% Equity (common) VG
Neuren Pharmaceuticals Ltd 1.65% Equity (common) NZ
TSHA Taysha Gene Therapies Inc 1.32% Equity (common) US
Dynavox Group AB 1.24% Equity (common) SE
CAPR Capricor Therapeutics Inc 1.15% Equity (common) US
Idorsia Ltd 1.03% Equity (common) CH
ANNX Annexon Inc 1.01% Equity (common) US
RAPP Rapport Therapeutics Inc 0.98% Equity (common) US
IART INTEGRA LIFESCIENCES HOLDINGS CORPORATION 0.96% Equity (common) US
SanBio Company Limited 0.91% Equity (common) JP
Zylox-Tonbridge Medical Technology Co Ltd 0.81% Equity (common) CN
DRUG Bright Minds Biosciences Inc 0.80% Equity (common) CA
Medincell SA 0.72% Equity (common) FR
FULC Fulcrum Therapeutics Inc 0.68% Equity (common) US
RGNX Regenxbio Inc 0.68% Equity (common) US
MicroPort NeuroScientific Corp 0.62% Equity (common) KY
CBLL Ceribell Inc 0.60% Equity (common) US
AVXL Anavex Life Sciences Corp 0.56% Equity (common) US
VNDA VANDA PHARMACEUTICALS INC. 0.54% Equity (common) US
BNTC Benitec Biopharma Inc 0.52% Equity (common) US
NPCE Neuropace Inc 0.51% Equity (common) US
PEIJIA MEDICAL LIMITED 0.50% Equity (common) KY
PRTA Prothena Corporation PLC 0.50% Equity (common) IE
SLDB Solid Biosciences Inc 0.49% Equity (common) US
Oncolys Biopharma Inc 0.41% Equity (common) JP
CLPT Clearpoint Neuro Inc 0.41% Equity (common) US
Geographic Breakdown
Fund Holdings
iShares Neuroscience and Healthcare ETF · NPORT-P period 2026-07-31 (filed 2026-03-25)
Net assets: $5M · 68 total positions · equity 93.10% · non-equity 20.24%
# Symbol Issuer Weight Value
1 PRAXIS PRECISION MEDICINES INC Praxis Precision Medicines Inc 5.02% $245548
2 AXSOME THERAPEUTICS INC AXSOME THERAPEUTICS, INC. 4.90% $239341
3 ALKERMES PLC ALKERMES PUBLIC LIMITED COMPANY 4.55% $222590
4 BIOGEN INC BIOGEN INC. 3.93% $192302
5 SCHOLAR ROCK HOLDING CORP Scholar Rock Holding Corp 3.91% $190928
6 PTC THERAPEUTICS INC PTC THERAPEUTICS, INC. 3.88% $189580
7 DENALI THERAPEUTICS INC Denali Therapeutics Inc 3.71% $181268
8 ACADIA PHARMACEUTICALS INC ACADIA PHARMACEUTICALS INC. 3.63% $177543
9 XENON PHARMACEUTICALS INC Xenon Pharmaceuticals Inc 3.61% $176630
10 CATALYST PHARMACEUTICALS INC CATALYST PHARMACEUTICALS, INC. 3.53% $172773
11 NEUROCRINE BIOSCIENCES INC NEUROCRINE BIOSCIENCES, INC. 3.47% $169667
12 SUPERNUS PHARMACEUTICALS INC SUPERNUS PHARMACEUTICALS, INC. 3.44% $168223
13 SK BIOPHARMACEUTICALS CO LTD SK Biopharmaceuticals Co Ltd 3.01% $146948
14 EDGEWISE THERAPEUTICS INC Edgewise Therapeutics Inc 2.82% $137851
15 AVADEL PHARMACEUTICALS PLC AVADEL PHARMACEUTICALS PUBLIC LIMITED COMPANY 2.64% $129084
16 SAREPTA THERAPEUTICS INC SAREPTA THERAPEUTICS, INC. 2.64% $128874
17 DYNE THERAPEUTICS INC Dyne Therapeutics Inc 2.46% $120453
18 DIANTHUS THERAPEUTICS INC Dianthus Therapeutics Inc 2.46% $120288
19 H LUNDBECK A S H. LUNDBECK A/S 2.35% $115013
20 AXOGEN INC AxoGen, Inc. 2.06% $100542
21 BIOARCTIC AB BioArctic AB 1.82% $89204
22 BIOHAVEN LTD Biohaven Ltd 1.68% $82065
23 NEUREN PHARMACEUTICALS LTD Neuren Pharmaceuticals Ltd 1.65% $80474
24 TAYSHA GENE THERAPIES INC Taysha Gene Therapies Inc 1.32% $64610
25 DYNAVOX GROUP AB Dynavox Group AB 1.24% $60763
Showing top 25 of 56 equity holdings.
Non-equity holdings — 12 positions, 20.24% of NAV
Category Weight Value Positions
Short-term investment 13.34% $652077 2
Other 6.90% $337547 10
Price History
Seasonality
MonthAvg ReturnYears of Data
Jan +1.49% 4
Feb -4.18% 4
Mar -3.76% 4
Apr +1.20% 4
May -1.17% 4
Jun -1.32% 4
Jul +4.03% 3
Aug -2.12% 4
Sep +0.59% 4
Oct +3.45% 4
Nov +3.72% 4
Dec +1.72% 4
Technical Indicators

Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.

Trend Indicators
  • SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
  • EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
  • MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
  • ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
  • +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
  • RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
  • Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
  • Williams %R — inverted scale: <−80 oversold, >−20 overbought.

Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.

Volume & Volatility
  • Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
  • OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
  • Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
  • ATR / True Range — average daily $ move; sizing and stop-loss reference.
  • HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.

Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →

Trend Indicators
SMA 20: $34.66
SMA 50: $34.70
SMA 200: $31.33
Current: $34.84
EMA 12: $34.62
EMA 26: $34.67
MACD: -0.0488 | Signal: -0.0579
BULLISH
ADX (14): 15.74
RANGE
+DI: 40.58
−DI: 26.66
Momentum Oscillators
RSI (14): 51.32
NEUTRAL
Stoch %K: 26.11
Stoch %D: 26.41
Williams %R: -61.24
Volume & Volatility
BB Upper: $35.86
BB Lower: $33.45
NEUTRAL
OBV: 90,302
Vol SMA 20: 1,841
Vol ROC: 331.89%
ATR: $0.80
True Range: $0.54
HV 20: 30.5%
HV 30: 26.5%
HV 60: 29.1%

Data Summary
Data Points: 500
Last Updated: 2026-06-12T21:15:14.785000
Date Range: 2024-06-14T00:00:00 – 2026-06-12T00:00:00
AI Analysis

Choose Frenzy-Fast™ for quick analysis or Frenzy-Pro™ for comprehensive analysis.

Analysis includes technical indicators, news sentiment, risk assessment, and specific price levels to watch.

News
Options Activity
IV Rank (30D)
41.25
IV Rank (7D)
87.06
Avg IV
52.0%
Straddle (30D)
$2.60
Straddle (7D)
$1.75
Spread Scanner GPU

Each spread is ranked by a composite score built in three stages. Full documentation →

Stage 1 — Base Score (GPU scanner)

score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.

Stage 2 — Skew Adjustment (±25% cap)

RR25 and BF25 from the live options chain. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.

Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
  • RSI <40 bullish / >60 bearish
  • MACD crossover + histogram trend
  • Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
  • Stochastic %K <20 / >80
  • Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
  • Blended ATR + straddle expected-move penalty
  • Bollinger Band signal (+ counter-trend penalty)
  • BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
  • IV rank ≥ 75 → strong boost for credit spreads
  • IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
  • Min open interest across all legs
  • OI < 100 → −0.10 · OI < 500 → −0.05

score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →

Enter a ticker to scan for optimal spread opportunities.

Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.

Volatility Surface

Enter a ticker to render the implied volatility surface.

IV Rank (7 DTE)
IV Rank (30 DTE)
Straddle Price (30 DTE)
Beta Analysis
Beta (1Y vs SPY)
1.20
Correlation (SPY)
57.7%
0.33
Ann. Volatility
25.7%
SPY Volatility
12.3%

Above average volatility - stock moves with market amplification

Beta & Alpha Over Time
Constituent Performance

Click any bar to view the full quote for that stock.

Constituents
Symbol Price 1 Day 1 Week 1 Month