NBIX Neurocrine Biosciences Inc

XNAS 168.21 Delayed
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Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership. Iron condor setups Expected move IV rank history Fibonacci levels Insider trading

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.

NBIX $168.21 —
Key stats
$168.21
52-Week Range
$122.14 – $186.12
YTD
+19.64%
IV Rank (30D)
30.4
Straddle Price
$13.90
P/C Vol Ratio
0.33
Market Cap
$16.7B
Open
$166.66
Day Range
$162.99 – $168.58
Volume
762,913
Prev Close
$164.63
Fair Value
+50.0% vs price

A blended fair-value estimate combining up to six valuation methods. Each method is weighted by how well it fits the company — DCF down-weights for unprofitable names; DDM only fires for steady dividend payers; comparables down-weight when peer multiples disagree.

  • DCF (quality-aware) — projects free cash flow with a horizon that scales to business quality. True compounders (quality 6/6) get 10 years explicit + 10 years fade before terminal; cyclical/struggling names (quality 0-1) get a 5-year terminal cliff. Quality is scored from ROE, gross margin, growth, FCF margin, debt load, and FCF consistency — the same factors that drive market premium for compounders.
  • Market-Implied Growth (in Model Inputs) — reverse-DCF that answers "what growth rate is the market pricing in?". Lets you sanity-check the deviation: if implied growth is plausible for the business, the model's bearish flag may be wrong; if implausible, the market may be over-extrapolating.
  • DDM (Gordon Growth Dividend Model) — values the stream of future dividends. Only used when trailing yield ≥ 2% and dividend payments are stable — below that the dividend is a token payout and Gordon (which values only the dividend stream) systematically underprices growth names, so those route to DCF + comparables + market anchor instead.
  • P/E, EV/EBITDA, P/B, P/S — applies the peer-group median multiple to this company's per-share metric. Peers come from the same set as the "Related symbols" card. Earnings/sales metrics are forward-tilted by the company's recent revenue growth (capped at 25%) so they're comparable to peers' growth-embedded multiples — mimics how analysts use NTM rather than TTM. Per-multiple weights are biased by company quality (e.g. P/B down-weighted for asset-light tech).
  • Market Anchor (SMA50) — the 50-day moving average, weighted by recent trading-range stability (tighter Bollinger bands → higher weight). Captures information fundamentals miss (forward consensus, sentiment, supply/demand) — but only when recent trading is steady enough that the market has converged on a view. During wild breakouts or breakdowns the anchor's weight collapses.
  • Options Expected (B-L 30d) — the risk-neutral expected stock price at 30-day options expiration, derived from the full implied-volatility surface via Breeden-Litzenberger (second derivative of call price wrt strike → implied PDF, then E[S_T]). Forward-looking, captures all options-implied information (smile, skew, term structure) in one number. Weighted by chain liquidity. SP500-only at present (pre-computed daily). Backtest evidence: adds modest alpha across most bucket × holding combos.
  • Blended value — weighted average. Confidence reflects how many methods fired and how tight peer dispersion is.
  • Deviation pill — green when blended FV ≥ 10% above current price (undervalued); red when ≥ 10% below; grey otherwise.
10-yr Treasury (rf)4.90%
Beta vs SPY0.63
Cost of Equity (CAPM)8.07% (VRP-adj)
WACC8.21%
Volatility Risk Premium+12.0pp (IV − HV30)
Effective Tax Rate24.6%
Rev. Growth (YoY, DCF input)+30.0%
DCF Horizon15 years explicit + fade
Forward Tilt (NTM/TTM)×1.10 (applied to P/E, EV/EBITDA, P/S)
Free Cash Flow (TTM)$1.0B
Return on Equity (TTM)18.1%
Book / Price22.4%
Gross Margin (TTM)97.8%
FCF Margin (TTM)28.1%
Debt / Equity0.00
Quality Score6/6 — compounder (15y DCF)
Market-Implied Growth+1.0% (reverse-DCF on current price)
SMA 50$147.22 (Market Anchor value)
SMA 20 / Bollinger Mid$146.09
Bollinger Width / SMA2026.4% (drives anchor stability)
Net Debt$-0.6B
Market Cap$17B
Peers used for multiples: ABBV, AMGN, BIIB, DFTX, EXEL, GILD, REGN, VRTX
Blended Fair Value
$527.39
Deviation
+50.0%
MethodImplied PriceWeightDetail
DCF $1378.92 28%
DDM (Gordon) n/a 0%
Peer P/E $226.50 13% median 30.6× · 6 peers
Peer EV/EBITDA $199.11 13% median 18.6× · 7 peers
Peer P/B $242.60 3% median 6.6× · 7 peers
Peer P/S $259.72 8% median 6.7× · 7 peers
Market Anchor (SMA50) $147.22 10% stability 18% (BB-width)
Options Expected (B-L 30d) $165.09 25% 18 strikes · skew +0.70
As of 2026-11-09 · updated
About
Industry (SIC)
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES) (2836) · industry map
Exchange
XNAS
Market Cap
$16.7B
Employees
2,500
List Date
1996-05-23
CIK
0000914475
Last Earnings
Nov 2 after close · +13.4% vs ±10.3% expected
Next Earnings
~Feb 10, 2027 (estimated)
Headquarters
San Diego, CA
Homepage
https://www.neurocrine.com

Neurocrine Biosciences Inc is a biopharmaceutical firm focused on the research, development, and commercialization of treatments for neurological, psychiatric, endocrine, and immunological disorders. Its portfolio includes therapies for conditions such as tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency, and treatments for endometriosis and uterine fibroids. The company also maintains a pipeline of drug candidates in various stages of clinical and preclinical development across its therapeutic areas, includ…

Summary
—
composite
—
No summary data available for this symbol yet.

Each spoke is this symbol's rank within its sector (0–100; the dotted ring marks the sector median at 50). Higher is more constructive for a long. One spoke — News sentiment — is an absolute reading, not a sector rank. Grayed spokes have no data. A fuller shape is a summary, not a recommendation.

Chart
Seasonality
Month'21'22'23'24'25'26Avg
Jan14.48%-10.68%-7.62%6.10%10.13%-3.23%1.53%
Feb3.29%13.44%-6.46%-8.46%-20.91%-3.91%-3.84%
Mar-11.13%2.02%-0.03%5.04%-3.39%-0.48%-1.33%
Apr-3.76%-5.80%0.18%-2.72%0.64%-0.67%-2.02%
May2.77%2.49%-13.93%-5.33%15.41%20.12%3.59%
Jun2.55%5.10%3.41%-1.61%0.91%4.68%2.51%
Jul-4.36%-5.16%7.84%1.04%0.18%-0.80%-0.21%
Aug-0.74%13.69%5.27%-17.04%8.29%-7.34%0.35%
Sep0.33%0.55%1.69%-7.90%-1.09%-9.52%-2.66%
Oct3.89%7.87%-0.76%5.36%4.53%3.83%4.12%
Nov-21.62%6.45%4.53%3.71%7.19%15.91%*2.70%
Dec5.42%-5.44%12.50%8.43%-6.00%--2.98%
Total-12.85%23.48%3.77%-15.45%11.46%15.69%4.35%
Technical Indicators

Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.

Trend Indicators
  • SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
  • EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
  • MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
  • ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
  • +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
  • RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
  • Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
  • Williams %R — inverted scale: <−80 oversold, >−20 overbought.

Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.

Volume & Volatility
  • Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
  • OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
  • Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
  • ATR / True Range — average daily $ move; sizing and stop-loss reference.
  • HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.

Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →

Trend Indicators

SMA 20: $147.44
SMA 50: $147.50
SMA 200: $148.18
Current: $168.35
EMA 12: $155.85
EMA 26: $150.55
MACD: 5.3025 | Signal: 2.9222
BULLISH
ADX (14): 28.06
TREND
+DI: 35.39
−DI: 12.56

Momentum Oscillators

RSI (14): 71.97
OVERBOUGHT
Stoch %K: 84.04
Stoch %D: 82.93
Williams %R: -4.08

Volume & Volatility

BB Upper: $168.88
BB Lower: $126.00
NEUTRAL
OBV: 35,073,025
Vol SMA 20: 1,439,248
Vol ROC: -40.86%
ATR: $5.47
True Range: $5.59
HV 20: 53.6%
HV 30: 45.7%
HV 60: 36.8%

Data Summary

Data Points: 500
Last Updated:
Date Range: 2024-11-08T00:00:00 – 2026-11-06T00:00:00
AI Analysis
Written before NBIX’s Nov 2 earnings report, so it doesn’t reflect the results.

LLM Stock Analysis Report

Executive Summary

Overall Assessment: NEUTRAL (Confidence Level: 6/10)

Key Drivers:

  • Positive news sentiment from recent headlines
  • Low volatility relative to market
  • Technical indicators showing neutral momentum

Primary Risks:

  • Bearish MACD signal and weak trend indicators
  • Potential for a pullback or consolidation phase

Investment Thesis: NBIX has been trending sideways, with positive news flow supporting the stock. However, technical signals indicate a lack of clear direction, making it challenging to take a strong bullish or bearish stance. A breakout above $162.08 or below $149.14 could trigger more significant price movements.

Recent News Sentiment Impact: The recent headlines have been overwhelmingly positive, with Nxera Pharma's partner Neurocrine Biosciences receiving IND acceptance from the FDA for Phase 2 study of NBI-1117567 for Alzheimer's cognition. This news has contributed to the stock's neutral sentiment and moderate price movement.

Technical Analysis

Trend Direction:

  • Short-term (1-4 weeks): NEUTRAL
  • Medium-term (1-3 months): BEARISH
  • Long-term (3-12 months): NEUTRAL

Support/Resistance Levels: The key price levels to monitor are the SMA 20 ($155.61), SMA 50 ($165.88), and Bollinger Bands Upper ($162.08).

Momentum Signals:

  • RSI: 44.05 (NEUTRAL)
  • MACD: -2.38 / Signal: 0.83 / Histogram: -3.21 (BEARISH)
  • Bollinger Bands position: NEUTRAL

Volume Analysis: The volume has been trending downward, with the Volume Rate of Change indicating a decline in buying interest.

News & Sentiment Analysis

Recent Headlines Summary: The headlines have been primarily positive, highlighting Nxera Pharma's operational highlights and consolidated results, as well as partner Neurocrine Biosciences' progress in their Phase 2 study.

Sentiment Assessment: The sentiment is NEUTRAL, with a slight bias towards positivity due to the recent news flow.

Catalyst Identification: The upcoming FDA approval for NBI-1117567 could be a significant catalyst, potentially driving price movements.

Market Narrative: The market narrative is that NBIX has been trending sideways, with positive news supporting the stock. The lack of clear direction in technical signals makes it challenging to take a strong stance.

Risk & Volatility Assessment

Risk Interpretation: Beta: 0.65 (LOW VOLATILITY)

Volatility Regime: Current vs historical volatility levels: LOW VOLATILITY

Options Market Signals: IV Rank: 5.3% (LOW), Current IV: 34.5%, Expected Move: $11.05, Volume Flow: 12 calls vs 39 puts

Downside Protection: The support level is at $155.61 (SMA 20), with potential for a pullback or consolidation phase.

Market Context & Positioning

Sector Performance: NBIX has been trending relatively stronger than the sector, with a sector-relative strength of +1.2%.

Institutional Activity: The institutional activity has been moderate, with no clear signs of increased interest.

Correlation Analysis: The stock moves relatively less than the market (R-squared interpretation), indicating low volatility.

Relative Valuation: NBIX is positioned within a trading range, with potential for breakout or consolidation.

Key Levels & Action Items

Critical Price Levels: Support: $155.61 (SMA 20), Resistance: $162.08 (Bollinger Bands Upper)

Breakout/Breakdown Levels: Bearish breakout below $149.14 could trigger significant price movements.

Time-Sensitive Catalysts: Upcoming FDA approval for NBI-1117567

Risk Management: Stop-loss levels and position sizing considerations should be based on the recent trend direction and volatility regime.

Please let me know if you need any further clarification or modifications to this report.

Generated
Earnings History
16 of 24 under expected move
Avg Expected Move
7.82%
Avg Actual Move
5.66%
Each row pairs the pre-earnings straddle-implied expected move with the realized close-to-close move. Sorted oldest first.
Earnings Date Timing Expected Move Actual Move Ratio Outcome
2021-01-08 After-Close 7.28% 1.58% 0.22x Within
2021-05-05 After-Close 8.46% 2.37% 0.28x Within
2021-08-03 After-Close 7.57% 4.61% 0.61x Within
2021-11-01 After-Close 8.95% 10.02% 1.12x Exceeded
2022-01-06 After-Close 8.06% 8.74% 1.08x Exceeded
2022-05-04 After-Close 3.37% 3.53% 1.05x Exceeded
2022-08-04 After-Close 6.36% 8.45% 1.33x Exceeded
2022-11-01 After-Close 4.94% 2.26% 0.46x Within
2023-02-06 After-Close 4.11% 1.14% 0.28x Within
2023-05-03 After-Close 7.02% 2.82% 0.40x Within
2023-08-01 After-Close 4.86% 0.68% 0.14x Within
2023-10-31 After-Close 5.41% 0.54% 0.10x Within
2024-02-07 After-Close 5.03% 1.37% 0.27x Within
2024-05-01 After-Close 5.94% 2.24% 0.38x Within
2024-08-01 After-Close 13.74% 0.01% 0.00x Within
2024-10-30 After-Close 5.59% 3.27% 0.58x Within
2025-02-06 After-Close 12.79% 18.53% 1.45x Exceeded
2025-05-05 After-Close 10.71% 8.36% 0.78x Within
2025-07-30 After-Close 8.37% 6.24% 0.75x Within
2025-10-28 After-Close 12.30% 6.35% 0.52x Within
2026-02-11 After-Close 8.33% 10.43% 1.25x Exceeded
2026-05-05 After-Close 8.96% 8.86% 0.99x Within
2026-07-30 After-Close 9.22% 10.08% 1.09x Exceeded
2026-11-02 After-Close 10.32% 13.42% 1.30x Exceeded

Earnings calendar: this week’s reports with expected vs actual moves →

NBIX Options Activity & IV Rank

NBIX IV rank history, 52-week IV rank and IV percentile →

Volatility Metrics

Current IV: 31.7%
7-DTE IV: 33.7%
Expected Move: $13.90
7-DTE Move: $8.28
Days to Exp: 39 (2026-12-18)

Options Flow · All expiries

Call Volume: 2,537
Put Volume: 825
P/C Volume: 0.325
BULLISH
Call OI: 15,463
Put OI: 7,360
P/C OI: 0.476
Total OI: 22,823

ATM Options Pricing

ATM Call: $5.75
ATM Put: $8.15
Call %: 3.4%
Put %: 4.8%

Chain Summary

Chain Volume: 3,362
Chain OI: 22,823
Last Updated: 11/9/2026
Spread Scanner

Each spread is ranked by a composite score built in three stages. Full documentation →

Stage 1 — Base Score

score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.
Calendars: the long leg is valued at the short leg’s expiration (Black-Scholes at its current IV) across the range of prices the short leg’s IV implies, giving the best-case profit (R/R = that over the debit) and P(profit).

Stage 2 — Skew Adjustment (±25% cap)

RR and BF (30-delta) from the persisted per-symbol skew snapshot — wing strikes picked by real greeks.delta, not a moneyness proxy. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.

Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
  • RSI <40 bullish / >60 bearish
  • MACD crossover + histogram trend
  • Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
  • Stochastic %K <20 / >80
  • Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
  • Blended ATR + straddle expected-move penalty
  • Bollinger Band signal (+ counter-trend penalty)
  • BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
  • IV rank ≥ 75 → strong boost for credit spreads
  • IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
  • Min open interest across all legs
  • OI < 100 → −0.10 · OI < 500 → −0.05

score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →

Scanning bull put, bear call, iron condor and calendar spreads…

Dealer Positioning
TYPICAL γ

Estimated net dealer gamma is at the 37th percentile of this name's own daily history, within its typical range. This describes current positioning; it is not a forecast or a trading signal.

Gamma percentile
37%
vs own history
GEX tilt
+0.02
OI-weighted, today
Vanna tilt
+0.42
δ-sensitivity to IV
Charm tilt
-0.41
δ-decay vs time
Vanna tilt +0.42: the estimated dealer exposure leans positive, so the modeled hedge would shift noticeably if implied volatility changed.
Charm tilt -0.41: the estimated dealer exposure leans negative, so the modeled hedge would shift noticeably as time passes and options approach expiry.

Net dealer gamma is an estimate of the aggregate gamma held by options market makers across this name's option chain, weighted by open interest. Dealer positions aren't public, so it uses a standard simplifying assumption: dealers are treated as long the calls and short the puts that are open. Actual dealer books can differ.

Gamma percentile ranks today's estimate against this name's own daily history, from 0% (the lowest reading on record) to 100% (the highest). Raw gamma scales with how much open interest a chain carries, so it isn't comparable across names; the percentile is. The badge marks the bottom 20% as low and the top 20% as high.

Tilts run from −1 to +1 and show how lopsided the estimated dealer exposure is. GEX tilt compares call gamma with put gamma. Vanna tilt describes how the hedge would shift if implied volatility changed, and charm tilt how it would shift with the passage of time.

This card describes estimated positioning and where it sits historically. It is not a forecast of price direction or volatility and not a trading signal. Market-wide view: Dealer positioning screener.

· 39 ATM contracts, 6k total OI
Skew (Wing IV − ATM IV)
DTE:
Wing Δ:
Metric:
Wing vs ATM
IV(put wing) − IV(ATM), in vol points

How much the OTM put trades above (or below) the at-the-money strike. Measures the height of the put-side tail relative to ATM — i.e. how expensive crash insurance is on this name.

  • Positive (typical) — wing IV > ATM IV. Standard equity put skew: portfolios bid up crash protection, so OTM puts trade richer than ATM.
  • Near zero or negative (unusual) — wing IV ≤ ATM IV. Flat or inverted put side. Common when there's no fear demand, in tightly mean-reverting names, or right after an earnings catalyst clears.
  • Percentile vs own 3-yr history: high = wings rich (good time to sell wing premium); low = wings cheap (good time to buy protection).
  • Not directional — high or low wings don't predict up or down moves. It's a price tag on tail insurance, not a forecast.
Risk Reversal
IV(call wing) − IV(put wing), equal delta on each side

Which side of the smile is the market paying up for? Measures the tilt of the surface — call skew vs put skew at matched deltas.

  • Negative (typical) — puts richer than calls. Standard equity behavior: hedging demand makes puts carry a premium. Most large-caps sit in the −1 to −5 vol-point range.
  • Strongly negative (< −5 pts) — heavy downside hedging, elevated fear, or an upcoming catalyst (earnings, FDA, macro event). Worth flagging.
  • Positive — calls richer than puts. Unusual for equities; signals bullish momentum, short-squeeze positioning, or takeover/M&A speculation.
  • Near zero — symmetric surface. Market sees roughly equal up/down risk. Rare for large-caps; more common in commodities and FX.
Reading them together

Wing-vs-ATM tells you how expensive the tails are. Risk Reversal tells you which side is favored. Combined:

  • High wing percentile + deeply negative RR → strong put bid; stress or major event priced in. Owning protection costs a premium; selling put premium is dangerous.
  • Low wing percentile + near-zero RR → complacency; insurance cheap and balanced. Good environment to add cheap downside hedges.
  • Positive RR + elevated wings → call-side fear-of-missing-out; common in squeeze setups. Upside calls expensive, downside puts not bid.
14 DTE / 10d —
— pts EXTREME
No data
30 DTE / 10d —
— pts EXTREME
No data

Percentile is the rank of today's reading within ~3 years of this symbol's own history. High percentile = wings are rich relative to history; not a directional signal. Skew is read off the chain in real time, not from CBOE SKEW.

Volatility Surface

Loading the implied volatility surface…

Volatility Smile

Loading the implied volatility smile…

IV Rank (7 DTE)23.4LowNov 9
IV Rank (30 DTE)30.4MediumNov 9
Straddle Price (30 DTE)$13.90Nov 9
Beta Analysis

Risk Metrics

Beta: 0.6555
Alpha: 8.02%
Correlation: 0.2572
R-Squared: 6.6%
Stock Volatility: 35.0%
Market Volatility: 13.7%

Analysis Details

Benchmark: SPY
Data Points: 251
Period: 252 trading days
Interpretation:
Low volatility - stock moves less than market
Beta & Alpha Over Time
Notable investors who own NBIX
5 of 37 tracked investors
InvestorValueShare of their portfolioRankQ/Q sharesSource
Renaissance Technologies Hedge fund
Jim Simons
$393.7M
0.54%
#28 of 3138-3.4%13F
Rockefeller Capital Management Family office
Rockefeller family
$63.0M
0.10%
#193 of 4729+32.4%13F
Bridgewater Associates Hedge fund
Ray Dalio
$34.7M
0.14%
#117 of 997+38.8%13F
Citadel Hedge fund
Ken Griffin
$2.0M
0.00%
#2923 of 6285-79.5%13F
Millennium Management Hedge fund
Izzy Englander
$2.0M
0.00%
#2593 of 3716-99.1%13F

Hedge funds, activists, holding companies and family offices we track, from their latest 13F (quarter-end value) and Form 4 filings in the last 3 years. Family offices · all institutions

NBIX Institutional Ownership (13F)

Filings for 2026-06-30 · 362 already for 2026-09-30
Diluted shares outstanding: 104,200,000 (as of 2026-09-30)

Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.

  • Shares — long equity positions in this name, aggregated across share classes.
  • Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
  • % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
  • Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.

Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.

787 filers104,317,011 shares$17.09B value100.11% of float
# Filer Shares Value % of Total % of Float Period
1 BlackRock, Inc. Custodian 13,711,607 $2.31B 13.52% 13.16% 2026-06-30
2 JPMorgan Chase & Co Custodian 6,398,674 $1.09B 6.37% 6.14% 2026-06-30
3 Dodge & Cox 5,584,707 $941.22M 5.51% 5.36% 2026-06-30
4 Vanguard Portfolio Management LLC 4,974,083 $838.31M 4.90% 4.77% 2026-06-30
5 Vanguard Capital Management LLC 4,545,339 $766.05M 4.48% 4.36% 2026-06-30
6 State Street Corp 4,385,598 $739.13M 4.32% 4.21% 2026-06-30
7 AQR Capital Management, LLC Custodian 3,818,037 $643.47M 3.76% 3.66% 2026-06-30
8 RENAISSANCE TECHNOLOGIES LLC 2,335,897 $393.68M 2.30% 2.24% 2026-06-30
9 Two Sigma Investments, LP Custodian 2,076,260 $349.92M 2.05% 1.99% 2026-06-30
10 Vestal Point Capital, LP 1,880,000 $316.85M 1.85% 1.80% 2026-06-30
11 Geode Capital Management, LLC Custodian 2,127,482 $301.04M 1.76% 2.04% 2026-09-30
12 BNP PARIBAS ASSET MANAGEMENT Holding S.A. 1,494,259 $251.86M 1.47% 1.43% 2026-06-30
13 Morgan Stanley Custodian 1,318,607 $222.23M 1.30% 1.27% 2026-06-30
14 RTW INVESTMENTS, LP 1,267,925 $213.69M 1.25% 1.22% 2026-06-30
15 Northern Trust Corp Custodian 1,259,717 $212.31M 1.24% 1.21% 2026-06-30
16 Invesco Ltd. Custodian 1,077,317 $181.57M 1.06% 1.03% 2026-06-30
17 Charles Schwab Investment Management, Inc. 974,279 $164.20M 0.96% 0.94% 2026-06-30
18 Norges Bank 973,880 $164.13M 0.96% 0.93% 2026-06-30
19 First Trust Advisors LP 923,125 $155.58M 0.91% 0.89% 2026-06-30
20 JACOBS LEVY EQUITY MANAGEMENT, INC 726,112 $122.38M 0.72% 0.70% 2026-06-30
21 Thrivent Financial for Lutherans 824,033 $116.88M 0.68% 0.79% 2026-09-30
22 Aberdeen Group plc 1,183,444 $112.81M 0.66% 1.14% 2026-09-30
23 Dimensional Fund Advisors LP Custodian 784,568 $111.25M 0.65% 0.75% 2026-09-30
24 Vanguard Fiduciary Trust Co 647,763 $109.17M 0.64% 0.62% 2026-06-30
25 IEQ CAPITAL, LLC 640,304 $107.91M 0.63% 0.61% 2026-06-30
11 filers$92.42M notional
# Filer Notional Value % of Total Period
1 Nantahala Capital Management, LLC $33.71M 36.47% 2026-06-30
2 Citigroup Inc. Custodian $17.05M 18.45% 2026-09-30
3 Susquehanna International Group, LLP Custodian $15.07M 16.30% 2026-06-30
4 JPMorgan Chase & Co Custodian $8.84M 9.57% 2026-06-30
5 Citadel Advisors LLC Custodian $5.70M 6.16% 2026-06-30
6 IMC-Chicago, LLC Custodian $4.61M 4.99% 2026-09-30
7 Jane Street Group, LLC Custodian $3.27M 3.54% 2026-06-30
8 Simplex Trading, LLC Custodian $3.22M 3.48% 2026-09-30
9 GROUP ONE TRADING LLC Custodian $623.58K 0.67% 2026-06-30
10 Walleye Capital LLC $269.66K 0.29% 2026-06-30
11 Raiffeisen Bank International AG $62.70K 0.07% 2026-09-30
12 filers$84.83M notional
# Filer Notional Value % of Total Period
1 Susquehanna International Group, LLP Custodian $31.21M 36.79% 2026-06-30
2 Jane Street Group, LLC Custodian $20.07M 23.66% 2026-06-30
3 Citigroup Inc. Custodian $13.39M 15.78% 2026-09-30
4 JPMorgan Chase & Co Custodian $5.10M 6.01% 2026-06-30
5 Citadel Advisors LLC Custodian $4.53M 5.34% 2026-06-30
6 IMC-Chicago, LLC Custodian $3.35M 3.95% 2026-09-30
7 Goldman Sachs Group Inc Custodian $2.31M 2.72% 2026-06-30
8 SIG BROKERAGE, LP $1.67M 1.97% 2026-06-30
9 Simplex Trading, LLC Custodian $1.55M 1.82% 2026-09-30
10 GROUP ONE TRADING LLC Custodian $977.50K 1.15% 2026-06-30
11 Walleye Trading LLC $623.58K 0.74% 2026-06-30
12 Walleye Capital LLC $50.56K 0.06% 2026-06-30

NBIX Insider Trading (Form 4)

Latest: 2026-11-05
Form 4 filings — insider beneficial-ownership changes by officers, directors, and 10%+ holders. Filed within 2 business days of transaction.
Filed Reporter Role Action Shares Avg Price Net $ Link
2026-11-05 Eiry Roberts Chief Medical Officer Grant (A) +9,820 opt — EDGAR
2026-11-03 Kyle Gano Chief Executive Officer Mixed
Exer +614 · Tax −332
+282 $146.10 -$48.5K EDGAR
2026-11-03 George J Morrow Director Mixed
Sell −15,000 · Exer +15,000
— $104.69 -$1.53M EDGAR
2026-09-15 Matt Abernethy Chief Financial Officer Mixed
Sell −2,311 · Tax −2,709 · Grant +5,020
— $156.67 -$786.5K EDGAR
2026-09-15 Darin Lippoldt Chief Legal Officer Mixed
Tax −2,419 · Grant +4,483
+2,064 $156.22 -$377.9K EDGAR
2026-09-15 David W. Boyer Chief Corp. Affairs Officer Mixed
Sell −826 · Tax −1,936 · Grant +3,587
+825 $156.59 -$432.5K EDGAR
2026-09-15 Kevin Charles Gorman Director Mixed
Grant +14,343 · Tax −7,839
+6,504 $156.22 -$1.22M EDGAR
2026-09-15 Sanjay Chandru Keswani Chief Medical Officer Mixed
Grant +3,914 · Tax −2,112
+1,802 $156.22 -$329.9K EDGAR
2026-09-15 Julie Cooke Chief Human Resources Officer Mixed
Grant +3,587 · Tax −1,936
+1,651 $156.22 -$302.4K EDGAR
2026-09-15 Eric Benevich Chief Commercial Officer Mixed
Tax −3,386 · Grant +6,275
+2,889 $156.22 -$529.0K EDGAR
2026-09-15 Ingrid Delaet Chief Regulatory Officer Mixed
Grant +4,483 · Tax −2,419
+2,064 $156.22 -$377.9K EDGAR
2026-09-15 Kyle Gano Chief Executive Officer Mixed
Grant +8,117 · Tax −4,380
+3,737 $156.22 -$684.2K EDGAR
2026-09-15 Jude Onyia Chief Scientific Officer Mixed
Grant +3,587 · Tax −1,936
+1,651 $156.22 -$302.4K EDGAR
2026-09-10 Eric Benevich Chief Commercial Officer Mixed
Exer +3,194 · Sell −2,154
+1,040 $88.10 -$194.9K EDGAR
2026-09-03 Stephen A Sherwin Director Gift (G) −1,000 — EDGAR
Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (described in filing footnote — typically 401(k), trust, inheritance) · W = will/inheritance. Only P / S codes carry directional signal.

NBIX Insider Holdings

20 insiders · @ $168.35
Officers, directors, and 10%+ owners who have filed a Form 4 in the past two years, ranked by current disclosed exposure (shares × today's price). Shares are direct + indirect (via trusts / LLCs / spouse). Excludes unvested RSU and option grants — those aren't beneficially owned until vest.
# Insider Role Shares Disclosed Exposure Lifetime OM Net Filings Last Filed
1 Kevin Charles Gorman Director 517,797 $87.17M -$181.28M 74 2026-09-15
2 Kyle Gano Chief Executive Officer 155,010 $26.10M -$49.45M 60 2026-11-03
3 Gary A Lyons Director 122,141 $20.56M -$23.43M 57 2026-05-29
4 Eric Benevich Chief Commercial Officer 70,683 $11.90M -$47.31M 47 2026-09-15
5 Darin Lippoldt Chief Legal Officer 59,212 $9.97M -$35.08M 65 2026-09-15
6 Matt Abernethy Chief Financial Officer 47,828 $8.05M -$15.33M 35 2026-09-15
7 William H Rastetter Director 43,678 $7.35M -$13.07M 27 2026-05-29
8 Richard F Pops Director 37,798 $6.36M -$13.18M 39 2026-05-29
9 Eiry Roberts Chief Medical Officer 34,252 $5.77M -$21.23M 36 2026-11-05
10 Julie Cooke Chief Human Resources Officer 24,025 $4.04M -$20.50M 39 2026-09-15
Lifetime OM Net = signed sum of open-market buys (P) and sells (S) over their career; excludes grants, tax withholdings, and dispositions to issuer. A large negative number is normal for long-tenured executives — they've sold compensation grants over many years.

NBIX Board & Officers

As of SEC filings through Nov 5, 2026

Directors 11

Officers 11

  • Kyle Gano · Chief Executive Officer · listed since Nov 2024
  • Matt Abernethy · Chief Financial Officer · since Dec 1, 2017
  • Darin Lippoldt · Chief Legal Officer · since Oct 31, 2014
  • Eric Benevich · Chief Commercial Officer · listed since Jun 2015
  • Eiry Roberts · Chief Medical Officer · since Jan 8, 2018
  • Julie Cooke · Chief Human Resources Officer · since May 7, 2019
  • Jude Onyia · Chief Scientific Officer · since Nov 29, 2021
  • David W. Boyer · Chief Corp. Affairs Officer · since Feb 4, 2022
  • Ingrid Delaet · Chief Regulatory Officer · since Feb 9, 2023
  • Sanjay Chandru Keswani · Chief Medical Officer · since Jun 2, 2025
  • Andrew Ratz · Chief Technical Operations Off · since Mar 15, 2026
Changes in the last 10 years (18)
Mar 15, 2026Andrew Ratz became Chief Technical Operations Off
Jun 2, 2025Sanjay Chandru Keswani became Chief Medical Officer
Nov 1, 2024Kyle Gano listed as Chief Executive Officer (previously Chief Business Development Off) in SEC filings
Nov 1, 2024Kyle Gano first listed as a director in an SEC filing
May 28, 2024The company announced the departure of Kevin Charles Gorman as Chief Executive Officer in an SEC filing
Jul 11, 2023Christine A Poon became a director
Feb 9, 2023Ingrid Delaet became Chief Regulatory Officer
Feb 2, 2023Malcolm Lloyd-Smith listed as Chief Integration Officer (previously Chief Regulatory Officer) in SEC filings
Feb 4, 2022David W. Boyer became Chief Corp. Affairs Officer
Nov 29, 2021Jude Onyia became Chief Scientific Officer
Apr 15, 2021Johanna Mercier became a director
Feb 1, 2020Shalini Sharp became a director
Sep 10, 2019Leslie V Norwalk became a director
May 7, 2019Julie Cooke became Chief Human Resources Officer
Jan 8, 2018Eiry Roberts became Chief Medical Officer
Dec 1, 2017Matt Abernethy became Chief Financial Officer
Jan 12, 2017Kevin Charles Gorman listed as Chief Executive Officer (previously President and CEO) in SEC filings
Jan 9, 2017David-Alexandre C Gros became President & COO
Not reported recently (9)
  • Malcolm Lloyd-Smith · Last reported as Chief Integration Officer in an SEC filing dated Feb 8, 2023
  • Dimitri E. Grigoriadis · Last reported as Chief Research Officer in an SEC filing dated Feb 2, 2022
  • Haig P. Bozigian · Last reported as Chief Development Officer in an SEC filing dated Mar 29, 2021
  • Alfred Sandrock · Last reported as a director in an SEC filing dated May 23, 2019
  • Corinne H Nevinny · Last reported as a director in an SEC filing dated May 25, 2018
  • Christopher Flint OBrien · Last reported as Chief Medical Officer in an SEC filing dated Feb 7, 2018
  • Joseph A Mollica · Last reported as a director in an SEC filing dated Jun 8, 2017
  • Timothy P Coughlin · Last reported as Chief Financial Officer in an SEC filing dated Feb 8, 2017
  • David-Alexandre C Gros · Last reported as President & COO in an SEC filing dated Feb 8, 2017
Compiled from SEC filings by the company and its directors and officers. Dates are as stated in those filings. Where no filing says when someone left, we show the last filing that listed them.

NBIX Proposed Insider Sales (Form 144)

Latest: 2026-11-02
Last 30d: 2 filings · $2.2M notice value  ·  Last 90d: 5 filings · $3.6M notice value · 4 unique filers · 100% under 10b5-1 plans

What is Form 144? A notice of intent to sell restricted or control stock under Rule 144. Affiliates (officers, directors, 10%+ owners) and holders of restricted shares must file Form 144 when planning to sell more than 5,000 shares or $50,000 in any 3-month rolling window.

How it relates to Form 4: Form 144 is filed before the trade (up to 90 days in advance); Form 4 is filed within 2 business days after the trade executes. Not every Form 144 results in a sale — the filer may cancel or delay. Look for the corresponding Form 4 on the Insider Activity card to confirm a sale actually happened.

10b5-1 plans: Trades made under a pre-scheduled Rule 10b5-1 plan are not discretionary — they execute automatically on dates set months earlier, regardless of news. High 10b5-1 percentages mean less per-filing signal value, though cumulative selling volume still matters.

"Notice value": Aggregate market value the filer wrote into the Form 144 — i.e. the size of the planned sale, not necessarily the executed dollars. An amended notice (Form 144/A) replaces the original it amends, and cancelled notices are dropped, so neither is double-counted above. A filed value that is clearly inconsistent with the share count at the stock's price (a filer typo) shows as a dash and is left out of the totals.

Source & freshness: Sourced from public Form 144 filings. Refreshed daily; new filings typically appear here the morning after they are filed.

Top 90-day filers: GEORGE MORROW (2, $2.2M) · DAVID WARREN BOYER (1, $736K) · MATTHEW C ABERNETHY (1, $361K) · ERIC BENEVICH (1, $334K)
Filed Filer Role Shares Notice Value Planned Sale Broker Plan Link
2026-11-02 GEORGE MORROW Director 14,700 $2.15M 2026-11-02 Morgan Stanley Smith Barney LLC … 10b5-1 EDGAR
2026-10-30 GEORGE MORROW Director 300 $43.9K 2026-10-30 Morgan Stanley Smith Barney LLC … 10b5-1 EDGAR
2026-09-14 MATTHEW C ABERNETHY Officer 2,311 $361.0K 2026-09-14 Morgan Stanley Smith Barney LLC … 10b5-1 EDGAR
2026-09-14 DAVID WARREN BOYER Officer 4,714 $736.4K 2026-09-14 Morgan Stanley Smith Barney LLC … 10b5-1 EDGAR
2026-09-09 ERIC BENEVICH Officer 2,154 $334.2K 2026-09-09 Morgan Stanley Smith Barney LLC … 10b5-1 EDGAR
2026-07-10 INGRID DELAET Officer 4,367 $788.5K 2026-07-10 Morgan Stanley Smith Barney LLC … 10b5-1 EDGAR
2026-07-09 DARIN LIPPOLDT Officer 10,000 $1.78M 2026-07-09 Morgan Stanley Smith Barney LLC … 10b5-1 EDGAR
2026-07-07 INGRID DELAET Officer 14,571 $2.54M 2026-07-07 Morgan Stanley Smith Barney LLC … 10b5-1 EDGAR
2026-06-29 DARIN LIPPOLDT Officer 9,800 $1.65M 2026-06-29 Morgan Stanley Smith Barney LLC … 10b5-1 EDGAR
2026-06-26 DARIN LIPPOLDT Officer 200 $32.8K 2026-06-26 Morgan Stanley Smith Barney LLC … 10b5-1 EDGAR
Notice value is the aggregate market value the filer states they intend to sell — not a confirmed transaction. Compare to Insider Activity (Form 4) to see which planned sales actually executed. Market-wide feed: Planned sales (Form 144).
Recent SEC Filings
Latest: 2026-11-02
Current reports — material events the company must disclose within 4 business days (earnings releases, M&A, executive changes, etc.).
Filing Date Event Link
2026-11-02 Earnings results EDGAR
2026-09-28 Director or officer change EDGAR
2026-07-30 Earnings results EDGAR
2026-05-28 Director or officer change · Shareholder vote results EDGAR
2026-05-18 Material agreement · Acquisition or sale completed · New debt obligation · Regulation FD disclosure EDGAR
2026-05-05 Earnings results EDGAR
2026-04-06 Material agreement EDGAR
2026-02-11 Earnings results EDGAR
2025-11-24 Director or officer change EDGAR
2025-10-28 Earnings results EDGAR
Annual report — audited financial statements, MD&A, risk factors. Filed 60–90 days after fiscal year-end.
Filing Date Accession Link
2026-02-11 0000914475-26-000007 EDGAR
2025-02-10 0000914475-25-000037 EDGAR
2024-02-09 0000914475-24-000054 EDGAR
2023-02-09 0000914475-23-000011 EDGAR
2022-02-11 0000914475-22-000013 EDGAR
2021-02-05 0000914475-21-000020 EDGAR
2020-02-07 0001564590-20-003773 EDGAR
2019-02-08 0001564590-19-002328 EDGAR
2018-02-13 0001193125-18-042794 EDGAR
Quarterly report — unaudited financials and MD&A. Filed 40–45 days after each of the first three fiscal quarters.
Filing Date Accession Link
2026-11-02 0000914475-26-000054 EDGAR
2026-07-31 0000914475-26-000037 EDGAR
2026-05-05 0000914475-26-000026 EDGAR
2025-10-28 0000914475-25-000181 EDGAR
2025-07-30 0000914475-25-000158 EDGAR
2025-05-05 0000914475-25-000100 EDGAR
2024-10-30 0000914475-24-000211 EDGAR
2024-08-01 0000914475-24-000181 EDGAR
2024-05-01 0000914475-24-000117 EDGAR
2023-10-31 0000914475-23-000073 EDGAR
ETF Holders
230 ETFs hold NBIX
25 shown · $3.24B total exposure · 0.37% AUM-weighted avg weight
# ETF Provider Weight $ Exposure ETF AUM As Of
1 IJH iShares Core S&P Mid-Cap ETF iShares (BlackRock) 0.50% $605.6M $121.4B 2026-11-06
2 VTI Vanguard Morningstar Total Stock Market ETF Vanguard 0.02% $458.8M — 2026-09-30
3 VB Vanguard Morningstar Small-Cap ETF Vanguard 0.18% $324.6M — 2026-09-30
4 VBK Vanguard Morningstar Small-Cap Growth ETF Vanguard 0.41% $180.5M — 2026-09-30
5 VXF Vanguard Extended Market ETF Vanguard 0.17% $162.3M — 2026-09-30
6 XBI State Street® SPDR® S&P® Biotech ETF SPDR (State Street) 1.57% $157.4M $10.0B 2026-11-05
7 IBB iShares Biotechnology ETF iShares (BlackRock) 1.14% $125.0M $11.1B 2026-11-06
8 MDY State Street® SPDR® S&P MIDCAP 400® ETF Trust SPDR (State Street) 0.48% $124.0M $25.6B 2026-11-05
9 FBT First Trust NYSE® Arca® Biotechnology Index Fund First Trust 3.85% $114.2M $3.0B 2026-11-06
10 USMV iShares MSCI USA Min Vol Factor ETF iShares (BlackRock) 0.47% $112.0M $23.7B 2026-11-06
11 XMHQ Invesco S&P MidCap Quality ETF Invesco 1.90% $107.5M — 2026-11-05
12 IJK iShares S&P Mid-Cap 400 Growth ETF iShares (BlackRock) 1.00% $102.1M $10.2B 2026-11-06
13 SPMD State Street® SPDR® Portfolio S&P 400™ Mid Cap ETF SPDR (State Street) 0.49% $89.1M $18.3B 2026-11-05
14 VFLO VictoryShares Free Cash Flow ETF Nport 1.04% $80.4M — 2026-06-30
15 IWP iShares Russell Mid-Cap Growth ETF iShares (BlackRock) 0.45% $79.0M $17.3B 2026-11-06
16 IWR iShares Russell Mid-Cap ETF iShares (BlackRock) 0.12% $69.6M $56.9B 2026-11-06
17 IWF iShares Russell 1000 Growth ETF iShares (BlackRock) 0.05% $53.0M $114.6B 2026-11-06
18 COWZ Pacer US Cash Cows 100 ETF Nport 0.25% $47.2M — 2026-07-31
19 SCHM Schwab U.S. Mid-Cap ETF Nport 0.29% $42.8M — 2026-08-31
20 VHT Vanguard Health Care ETF Vanguard 0.19% $41.4M — 2026-09-30
21 SCHG Schwab U.S. Large-Cap Growth ETF Nport 0.06% $37.5M — 2026-08-31
22 DFAC Dimensional US Core Equity 2 ETF Dimensional 0.04% $36.0M — 2026-11-05
23 JGRO JPMorgan Active Growth ETF JPMorgan 0.36% $32.2M $9.0B 2026-11-06
24 DYNF iShares U.S. Equity Factor Rotation Active ETF iShares (BlackRock) 0.07% $30.4M $40.6B 2026-11-06
25 FMDE Fidelity Enhanced Mid Cap Core ETF Fidelity 0.34% $29.0M $8.6B 2026-11-05
Fundamentals

Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.

Metrics
  • Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
  • Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
  • Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
  • Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
How to read the bars
  • Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
  • YoY growth — compare to the same quarter a year earlier to remove seasonality.
  • Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
  • Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.

TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.

Trailing P/E
25.00
TTM Diluted EPS
$6.74
TTM Revenue
$3.70B
TTM Net Income
$702.50M
TTM Op. Cash Flow
$1.07B
Quarterly figures (12 quarters)
QuarterPeriod EndRevenueNet IncomeDiluted EPSOp. Cash Flow
Q3 '262026-09-30$1.12B$206.50M$1.96$395.20M
Q2 '262026-06-30$959.00M$144.40M$1.39$136.40M
Q1 '262026-03-31$814.50M$197.90M$1.91$145.80M
Q4 '252025-12-31$805.50M$153.70M$1.48$388.40M
Q3 '252025-09-30$794.90M$209.50M$2.04$227.50M
Q2 '252025-06-30$687.50M$107.50M$1.06$102.00M
Q1 '252025-03-31$572.60M$7.90M$0.08$64.80M
Q4 '242024-12-31$627.70M$103.10M$1.00$242.50M
Q3 '242024-09-30$622.10M$129.80M$1.24$158.00M
Q2 '242024-06-30$590.20M$65.00M$0.63$64.60M
Q1 '242024-03-31$515.30M$43.40M$0.42$130.30M
Q4 '232023-12-31$515.20M$147.70M$1.46$123.50M
Q3 2026 • period ending 2026-09-30 • filed 2026-11-02
Valuation

Ratios derived from TTM financials and the current market price, sampled daily. History chart shows how expensive the stock is today relative to its own recent past.

Price Multiples
  • P/E — price / TTM earnings. Rough market rule: 10–15 value, 15–25 market, >30 growth/premium. Negative when earnings are negative.
  • P/B — price / book value. Useful for financials and asset-heavy names; meaningless for asset-light software.
  • P/S — price / TTM revenue. Useful when earnings are negative or noisy (early-stage growth).
  • EV/EBITDA — capital-structure-neutral. <10 cheap, 10–15 reasonable, >20 rich. Good for comparing across leverage profiles.
  • EV/Sales — like P/S but accounts for debt + cash. Compare within sector.
Profitability & Yields
  • ROE — return on equity. >15% strong, >25% exceptional. Caution: high leverage inflates ROE.
  • ROA — return on assets. Leverage-neutral; >5% solid, >10% exceptional.
  • Div Yield — annual dividend / price. Compare to 10Y Treasury; sustained yield >6% often signals distress.
  • FCF Yield — free cash flow / market cap. >5% is attractive; negative means burning cash.
Balance Sheet
  • Debt/Equity — leverage. <1 conservative, >2 aggressive. Sector-dependent (utilities naturally high, tech low).
  • Current Ratio — short-term liquidity. >1.5 comfortable, <1 raises short-term solvency flags.
Reading the history chart
  • Compare current level to the 3-year band: near the high end = relatively expensive; near the low = relatively cheap.
  • Multiples expanding while earnings are flat = sentiment-driven rally.
  • Multiples compressing while earnings grow = value coming from fundamentals.
P/E
25.00
P/B
4.71
P/S
5.15
EV/EBITDA
20.37
EV/Sales
5.05
ROE
19.1%
ROA
13.2%
Div Yield
0.00%
FCF Yield
5.17%
Debt/Equity
0.00
Current Ratio
—
Market Cap
$17.38B
as of 2026-11-09

NBIX vs Peers

Related companies, largest first
Company Market cap P/E Revenue growth YTD IV rank
ABBV ABBVIE INC. $514.9B 50.5 +10.7% +27.9% 34
AMGN Amgen Inc $249.0B 26.9 +8.2% +41.6% 33
GILD Gilead Sciences Inc $207.0B — +6.5% +39.4% 49
VRTX Vertex Pharmaceuticals Inc $138.7B 35.4 +10.5% +21.6% 63
REGN Regeneron Pharmaceuticals Inc $93.6B 20.5 +18.6% +19.5% 57
BIIB Biogen Inc. Common Stock $36.7B 110.3 +2.3% +45.1% 100
EXEL Exelixis Inc $17.0B 21.5 +9.1% +64.8% 37
NBIX Neurocrine Biosciences Inc $16.7B 25.0 +38.0% +19.7% 30
DFTX Definium Therapeutics, Inc. Common Share $4.5B — — +128.3% 24
Peer median $116.1B 31.1 +9.1% +40.5% 43

P/E uses the latest reported trailing-12-month diluted EPS; "—" means no positive earnings or no data.

Short Interest & Float

Regulatory short-interest reports publish on a bi-weekly settlement cadence; short-volume is reported daily by the trade-reporting facilities. Float is derived from insider-ownership filings.

Metric definitions
  • Short Interest — total shares currently sold short as of the settlement date. Lags real time by ~8 business days.
  • SI % of Float — short interest / free float. The key crowding metric.
  • Days to Cover — short interest / avg daily volume. How many full trading days it would take shorts to buy back. High DTC + catalyst = squeeze fuel.
  • Short Vol Ratio — today's short-sale volume / total volume. Intraday selling pressure proxy (not the same as short interest).
  • Free Float — shares available for public trading (total shares minus insider / restricted).
  • Float % — free float / shares outstanding. <50% = tightly held, more prone to squeezes.
How to read the signals
  • SI % of Float < 5% — typical, no particular signal.
  • 5–15% — elevated; watch for catalysts (earnings, guidance, macro).
  • 15–30% — heavily shorted; tight-float names in this range have produced notable squeezes historically.
  • >30% — extreme; borrow is likely expensive and squeeze risk is material.
  • Days to Cover > 5 combined with high SI% amplifies squeeze potential.
History chart
  • Trend matters more than level. Rapidly rising short interest often precedes negative catalysts or heavy hedging.
  • A sudden drop in SI after a rally may indicate a squeeze in progress.

Short interest is reported mid-month and end-of-month; short volume is daily.

Short Interest
6.45M
SI % of Float
6.62%
Days to Cover
4.54
Short Vol Ratio
50.1%
Free Float
97.42M
Float %
95.8%
Short interest 2026-10-15 • Short volume 2026-11-06 • Float 2026-08-24