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ARMISTICE CAPITAL, LLC — 13F Holdings & Portfolio

CIK 1601086 · latest 13F-HR filed 2026-05-15

Backtest portfolio

ARMISTICE CAPITAL, LLC manages $5.62B in 13F-reported U.S. long-equity assets across 267 reported positions as of its 2026-03-31 13F-HR filing. Its largest disclosed positions are SPY (24.28%), IWM (15.43%), TVTX (2.59%). Quarter over quarter (versus its 2025-12-31 filing) the fund opened 102 new positions, exited 208, added to 39, and trimmed 97.

AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.

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AUM

$5.62B

Long-equity book

Holdings

267

Distinct positions

Period

2026-03-31

Filed 2026-05-15

Q/Q Activity

+102 / −208 / ↑39 / ↓97

vs 2025-12-31

Firm Profile & Key People
Name Title / Status Ownership Type

Top Adds (vs prior quarter)

  • HARMONY BIOSCIENCES HLDGS IN$26.8M +143.1%
  • MEDLINE INC$22.7M +931.6%
  • NEKTAR THERAPEUTICS$16.4M +65.0%
  • ALIGN TECHNOLOGY INC$15.2M +127.9%
  • UBER TECHNOLOGIES INC$14.2M +61.5%
Show all 39 →

Top Trims

  • PTC THERAPEUTICS INC-$71.5M -33.6%
  • KENVUE INC-$68.4M -99.3%
  • IMMUNOVANT INC-$57.5M -39.4%
  • GE HEALTHCARE TECHNOLOGIES I-$56.5M -87.0%
  • DENTSPLY SIRONA INC-$48.6M -58.3%
Show all 97 →

New Positions

  • UNITEDHEALTH GROUP INC$40.0M
  • META PLATFORMS INC$18.6M
  • CENTRAL GARDEN & PET CO$15.5M
  • CAPRI HOLDINGS LIMITED$11.6M
  • XERIS BIOPHARMA HOLDINGS INC$11.1M
Show all 102 →

Exited Positions

  • ARGENX SE$48.8M
  • STARBUCKS CORP$46.3M
  • MEDTRONIC PLC$26.1M
  • DANAHER CORPORATION$24.5M
  • CVS HEALTH CORP$23.5M
Show all 208 →
All Holdings

Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).

# Issuer Symbol CUSIP Value Weight Shares Type
1 STATE STR SPDR S&P 500 ETF T Put SPY 78462F103 $1.37B 24.28% 2,100,000 SH
2 ISHARES TR Put IWM 464287655 $868.0M 15.43% 3,500,000 SH
3 TRAVERE THERAPEUTICS INC TVTX 89422G107 $145.5M 2.59% 4,897,417 SH
4 PTC THERAPEUTICS INC PTCT 69366J200 $141.3M 2.51% 2,074,449 SH
5 AGIOS PHARMACEUTICALS INC Call AGIO 00847X104 $108.3M 1.92% 3,200,000 SH
6 SUPERNUS PHARMACEUTICALS SUPN 868459108 $98.0M 1.74% 1,895,347 SH
7 NEUROCRINE BIOSCIENCES INC NBIX 64125C109 $95.4M 1.70% 724,000 SH
8 AGIOS PHARMACEUTICALS INC AGIO 00847X104 $91.9M 1.63% 2,716,000 SH
9 IMMUNOVANT INC IMVT 45258J102 $88.6M 1.57% 3,564,916 SH
10 FRESHPET INC FRPT 358039105 $64.5M 1.15% 1,093,307 SH
11 INCYTE CORP INCY 45337C102 $61.8M 1.10% 656,817 SH
12 DYNE THERAPEUTICS INC DYN 26818M108 $57.6M 1.02% 3,175,110 SH
13 CYTOKINETICS INC Call CYTK 23282W605 $56.0M 1.00% 850,000 SH
14 CYTOKINETICS INC Call CYTK 23282W605 $56.0M 1.00% 850,000 SH
15 AMAZON COM INC AMZN 023135106 $54.6M 0.97% 262,137 SH
16 IRONWOOD PHARMACEUTICALS INC IRWD 46333X108 $52.7M 0.94% 15,028,000 SH
17 MADRIGAL PHARMACEUTICALS INC MDGL 558868105 $52.3M 0.93% 100,000 SH
18 MADRIGAL PHARMACEUTICALS INC MDGL 558868105 $52.1M 0.93% 99,583 SH
19 CYTOKINETICS INC CYTK 23282W605 $50.4M 0.90% 764,538 SH
20 HARMONY BIOSCIENCES HLDGS IN HRMY 413197104 $45.5M 0.81% 1,624,000 SH
21 THERMO FISHER SCIENTIFIC INC TMO 883556102 $45.0M 0.80% 91,491 SH
22 NEKTAR THERAPEUTICS NKTR 640268306 $41.6M 0.74% 578,000 SH
23 UNITEDHEALTH GROUP INC UNH 91324P102 $40.0M 0.71% 148,000 SH
24 UBER TECHNOLOGIES INC UBER 90353T100 $37.3M 0.66% 518,760 SH
25 IMMUNOCORE HLDGS PLC IMCR 45258D105 $35.8M 0.64% 1,188,000 SH
26 DENTSPLY SIRONA INC XRAY 24906P109 $34.8M 0.62% 3,000,000 SH
27 RIGEL PHARMACEUTICALS INC RIGL 766559702 $34.6M 0.62% 1,280,000 SH
28 DISC MEDICINE INC IRON 254604101 $34.3M 0.61% 536,000 SH
29 ALPHABET INC GOOGL 02079K305 $34.1M 0.61% 118,514 SH
30 MADRIGAL PHARMACEUTICALS INC MDGL 558868105 $34.0M 0.61% 65,000 SH
31 MINERALYS THERAPEUTICS INC MLYS 603170101 $31.9M 0.57% 1,176,000 SH
32 HUBSPOT INC HUBS 443573100 $31.4M 0.56% 128,583 SH
33 AXOGEN INC AXGN 05463X106 $31.0M 0.55% 936,000 SH
34 ORTHOFIX MED INC OFIX 68752M108 $31.0M 0.55% 2,700,000 SH
35 KURA ONCOLOGY INC KURA 50127T109 $30.4M 0.54% 3,736,000 SH
36 AVANOS MED INC AVNS 05350V106 $28.0M 0.50% 2,000,000 SH
37 REGENERON PHARMACEUTICALS REGN 75886F107 $27.9M 0.50% 36,126 SH
38 ALIGN TECHNOLOGY INC ALGN 016255101 $27.1M 0.48% 157,959 SH
39 PTC THERAPEUTICS INC Call PTCT 69366J200 $26.6M 0.47% 390,000 SH
40 MONGODB INC MDB 60937P106 $26.3M 0.47% 107,296 SH
41 ALIBABA GROUP HLDG LTD BABA 01609W102 $25.6M 0.46% 204,000 SH
42 MEDLINE INC MDLN 58507V107 $25.1M 0.45% 564,857 SH
43 KALVISTA PHARMACEUTICALS INC KALV 483497103 $24.9M 0.44% 1,236,000 SH
44 DATADOG INC DDOG 23804L103 $24.6M 0.44% 208,564 SH
45 HUMANA INC HUM 444859102 $24.5M 0.44% 141,279 SH
46 SENTINELONE INC S 81730H109 $24.4M 0.43% 1,897,849 SH
47 VERASTEM INC VSTM 92337C203 $24.3M 0.43% 4,592,000 SH
48 FIVE9 INC FIVN 338307101 $24.2M 0.43% 1,592,000 SH
49 INTUITIVE SURGICAL INC ISRG 46120E602 $24.0M 0.43% 52,043 SH
50 GRIFOLS S A GRFS 398438408 $24.0M 0.43% 2,988,000 SH
Filing History
Period Filed AUM Holdings Accession
2026-03-31 2026-05-15 $5.62B 267 0001315863-26-000414
2025-12-31 2026-02-17 $8.40B 370 0001315863-26-000163
2025-09-30 2025-11-17 $6.74B 332 0001315863-25-000814