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TRV GP VI, LLC — 13F Holdings & Portfolio

CIK 1990716 · latest 13F-HR filed 2026-05-07

Backtest portfolio

TRV GP VI, LLC manages $135.6M in 13F-reported U.S. long-equity assets across 3 reported positions as of its 2026-03-31 13F-HR filing. Its largest disclosed positions are SEPN (74.64%), RAPP (22.37%), TNGX (3.00%). Quarter over quarter (versus its 2025-12-31 filing) the fund opened 0 new positions, exited 0, added to 1, and trimmed 1.

AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.

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AUM

$135.6M

Long-equity book

Holdings

3

Distinct positions

Period

2026-03-31

Filed 2026-05-07

Q/Q Activity

+0 / −0 / ↑1 / ↓1

vs 2025-12-31

Firm Profile & Key People
Name Title / Status Ownership Type

Top Adds (vs prior quarter)

  • TANGO THERAPEUTICS, INC.$2.3M +136.1%
Show all 1 →

Top Trims

  • SEPTERNA, INC.-$16.2M -13.8%
Show all 1 →

New Positions

  • No new positions this quarter.
Show all 0 →

Exited Positions

  • No exits this quarter.
Show all 0 →
All Holdings

Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).

# Issuer Symbol CUSIP Value Weight Shares Type
1 SEPTERNA, INC. SEPN 81734D104 $101.2M 74.64% 4,211,659 SH
2 RAPPORT THERAPEUTICS, INC. RAPP 75383L102 $30.3M 22.37% 969,218 SH
3 TANGO THERAPEUTICS, INC. TNGX 87583X109 $4.1M 3.00% 194,174 SH
Filing History
Period Filed AUM Holdings Accession
2026-03-31 2026-05-07 $135.6M 3 0001193125-26-212009
2025-12-31 2026-02-13 $148.5M 3 0001193125-26-051801