SPTX Seaport Therapeutics, Inc.

XNAS
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Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership. Iron condor setups Fibonacci levels Insider trading

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.

SPTX — —

What changed

Recent filings, trades and moves
Key stats
About
Industry (SIC)
PHARMACEUTICAL PREPARATIONS (2834) · industry map
Exchange
XNAS
Market Cap
$1.2B
List Date
2026-05-01
CIK
0002042347
Last Earnings
Aug 3
Headquarters
Boston, MA
Homepage
https://www.seaporttx.com

Seaport Therapeutics Inc is a clinical-stage therapeutics company. The company focuses on invention and development of new medicines for patients with depression, anxiety, and other debilitating neuropsychiatric disorders. The company identified clinically validated mechanisms with established efficacy and safety profiles, historically limited by high first-pass metabolism, low bioavailability, and side effects. The company's pipeline products are based on Glyph, company's lymphatic-targeting prodrug technology is designed to bypass first-pass metabolism and thereby enhance a drug's oral bioav…

Summary
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composite
—
No summary data available for this symbol yet.

Each spoke is this symbol's rank within its sector (0–100; the dotted ring marks the sector median at 50). Higher is more constructive for a long. One spoke — News sentiment — is an absolute reading, not a sector rank. Grayed spokes have no data. A fuller shape is a summary, not a recommendation.

Chart
Seasonality
'26Avg
Jan----
Feb----
Mar----
Apr----
May-8.32%-8.32%
Jun26.80%26.80%
Jul-5.47%-5.47%
Aug14.67%14.67%
Sep-14.57%-14.57%
Oct3.43%3.43%
Nov9.57%*9.57%
Dec----
Total22.00%22.00%
* Only 1 year(s) of data available.
Technical Indicators

Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.

Trend Indicators
  • SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
  • EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
  • MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
  • ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
  • +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
  • RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
  • Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
  • Williams %R — inverted scale: <−80 oversold, >−20 overbought.

Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.

Volume & Volatility
  • Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
  • OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
  • Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
  • ATR / True Range — average daily $ move; sizing and stop-loss reference.
  • HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.

Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →

Trend Indicators

SMA 20: $19.73
SMA 50: $20.63
SMA 200: —
Current: $21.93
EMA 12: $20.60
EMA 26: $20.23
MACD: 0.3683 | Signal: 0.2872
BULLISH
ADX (14): 17.06
RANGE
+DI: 27.35
−DI: 15.11

Momentum Oscillators

RSI (14): 59.47
NEUTRAL
Stoch %K: 78.06
Stoch %D: 74.21
Williams %R: -16.12

Volume & Volatility

BB Upper: $22.97
BB Lower: $16.48
NEUTRAL
OBV: 3,934,570
Vol SMA 20: 251,986
Vol ROC: 146.11%
ATR: $1.55
True Range: $1.41
HV 20: 63.2%
HV 30: 68.5%
HV 60: 73.4%

Data Summary

Data Points: 133
Last Updated:
Date Range: 2026-05-01T00:00:00 – 2026-11-09T00:00:00
AI Analysis

Click Frenzy-Pro™ for an AI analysis of this ticker.

Analysis includes technical indicators, news sentiment, risk assessment, and specific price levels to watch.

News
All SPTX news →

SPTX Options Activity & IV Rank

Loading options activity...
Spread Scanner
Full Algorithm Docs ↗

Each spread is ranked by a composite score built in three stages. Full documentation →

Stage 1 — Base Score

score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.
Calendars: the long leg is valued at the short leg’s expiration (Black-Scholes at its current IV) across the range of prices the short leg’s IV implies, giving the best-case profit (R/R = that over the debit) and P(profit).

Stage 2 — Skew Adjustment (±25% cap)

RR and BF (30-delta) from the persisted per-symbol skew snapshot — wing strikes picked by real greeks.delta, not a moneyness proxy. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.

Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
  • RSI <40 bullish / >60 bearish
  • MACD crossover + histogram trend
  • Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
  • Stochastic %K <20 / >80
  • Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
  • Blended ATR + straddle expected-move penalty
  • Bollinger Band signal (+ counter-trend penalty)
  • BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
  • IV rank ≥ 75 → strong boost for credit spreads
  • IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
  • Min open interest across all legs
  • OI < 100 → −0.10 · OI < 500 → −0.05

score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →

Scanning bull put, bear call, iron condor and calendar spreads…

Skew (Wing IV − ATM IV)
DTE:
Wing Δ:
Metric:
Wing vs ATM
IV(put wing) − IV(ATM), in vol points

How much the OTM put trades above (or below) the at-the-money strike. Measures the height of the put-side tail relative to ATM — i.e. how expensive crash insurance is on this name.

  • Positive (typical) — wing IV > ATM IV. Standard equity put skew: portfolios bid up crash protection, so OTM puts trade richer than ATM.
  • Near zero or negative (unusual) — wing IV ≤ ATM IV. Flat or inverted put side. Common when there's no fear demand, in tightly mean-reverting names, or right after an earnings catalyst clears.
  • Percentile vs own 3-yr history: high = wings rich (good time to sell wing premium); low = wings cheap (good time to buy protection).
  • Not directional — high or low wings don't predict up or down moves. It's a price tag on tail insurance, not a forecast.
Risk Reversal
IV(call wing) − IV(put wing), equal delta on each side

Which side of the smile is the market paying up for? Measures the tilt of the surface — call skew vs put skew at matched deltas.

  • Negative (typical) — puts richer than calls. Standard equity behavior: hedging demand makes puts carry a premium. Most large-caps sit in the −1 to −5 vol-point range.
  • Strongly negative (< −5 pts) — heavy downside hedging, elevated fear, or an upcoming catalyst (earnings, FDA, macro event). Worth flagging.
  • Positive — calls richer than puts. Unusual for equities; signals bullish momentum, short-squeeze positioning, or takeover/M&A speculation.
  • Near zero — symmetric surface. Market sees roughly equal up/down risk. Rare for large-caps; more common in commodities and FX.
Reading them together

Wing-vs-ATM tells you how expensive the tails are. Risk Reversal tells you which side is favored. Combined:

  • High wing percentile + deeply negative RR → strong put bid; stress or major event priced in. Owning protection costs a premium; selling put premium is dangerous.
  • Low wing percentile + near-zero RR → complacency; insurance cheap and balanced. Good environment to add cheap downside hedges.
  • Positive RR + elevated wings → call-side fear-of-missing-out; common in squeeze setups. Upside calls expensive, downside puts not bid.
14 DTE / 10d —
— pts EXTREME
ATM — / Wing —
30 DTE / 10d —
— pts EXTREME
ATM — / Wing —

Percentile is the rank of today's reading within ~3 years of this symbol's own history. High percentile = wings are rich relative to history; not a directional signal. Skew is read off the chain in real time, not from CBOE SKEW.

Volatility Surface

Loading the implied volatility surface…

Volatility Smile

Loading the implied volatility smile…

IV Rank (7 DTE)
IV Rank (30 DTE)
Straddle Price (30 DTE)
Beta Analysis

Risk Metrics

Beta: 0.7948
Alpha: 39.14%
Correlation: 0.1499
R-Squared: 2.2%
Stock Volatility: 74.5%
Market Volatility: 14.0%

Analysis Details

Benchmark: SPY
Data Points: 132
Period: 252 trading days
Interpretation:
Low volatility - stock moves less than market
Beta & Alpha Over Time
Notable investors who own SPTX
2 of 37 tracked investors
InvestorValueShare of their portfolioRankQ/Q sharesSource
Citadel Hedge fund
Ken Griffin
$4.2M
0.00%
#2249 of 6285new13F
Millennium Management Hedge fund
Izzy Englander
$985K
0.00%
#2913 of 3716new13F

Hedge funds, activists, holding companies and family offices we track, from their latest 13F (quarter-end value) and Form 4 filings in the last 3 years. Family offices · all institutions

SPTX Institutional Ownership (13F)

Filings for 2026-06-30 · 13 already for 2026-09-30

Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.

  • Shares — long equity positions in this name, aggregated across share classes.
  • Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
  • % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
  • Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.

Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.

60 filers37,670,110 shares$848.21M value
# Filer Shares Value % of Total % of Float Period
1 ARCH Venture Management, LLC 6,294,951 $136.60M 16.10% — 2026-06-30
2 GENERAL ATLANTIC, L.P. 6,101,582 $132.53M 15.62% — 2026-06-30
3 Sofinnova Investments, Inc. 3,564,871 $77.43M 9.13% — 2026-06-30
4 Goldman Sachs Group Inc Custodian 2,178,642 $47.32M 5.58% — 2026-06-30
5 TRV GP VI, LLC 2,061,222 $44.77M 5.28% — 2026-06-30
6 Canada Pension Plan Investment Board 1,975,791 $42.91M 5.06% — 2026-06-30
7 JPMorgan Chase & Co Custodian 1,815,845 $40.89M 4.82% — 2026-06-30
8 Foresite Capital Management VI LLC 1,779,521 $38.65M 4.56% — 2026-06-30
9 Aberdeen Group plc 267,678 $35.87M 4.23% — 2026-09-30
10 T. Rowe Price Associates, Inc. 1,308,604 $28.42M 3.35% — 2026-06-30
11 FMR LLC Custodian 1,185,100 $25.74M 3.03% — 2026-06-30
12 Bellevue Group AG 1,100,000 $23.89M 2.82% — 2026-06-30
13 Siren, L.L.C. 1,095,316 $23.79M 2.80% — 2026-06-30
14 Jennison Associates LLC 1,079,669 $23.45M 2.76% — 2026-06-30
15 RA CAPITAL MANAGEMENT, L.P. 700,000 $15.20M 1.79% — 2026-06-30
16 Vanguard Capital Management LLC 599,217 $13.01M 1.53% — 2026-06-30
17 Woodline Partners LP 586,345 $12.74M 1.50% — 2026-06-30
18 PERCEPTIVE ADVISORS LLC 500,000 $10.86M 1.28% — 2026-06-30
19 BRAIDWELL LP 500,000 $10.86M 1.28% — 2026-06-30
20 Principal Financial Group, Inc. 377,391 $7.61M 0.90% — 2026-09-30
21 Geode Capital Management, LLC Custodian 377,231 $7.61M 0.90% — 2026-09-30
22 UBS Group AG Custodian 279,184 $6.06M 0.71% — 2026-06-30
23 BlackRock, Inc. Custodian 229,863 $4.99M 0.59% — 2026-06-30
24 SEVEN GRAND MANAGERS, LLC 225,000 $4.89M 0.58% — 2026-06-30
25 Citadel Advisors LLC Custodian 191,144 $4.15M 0.49% — 2026-06-30
# Filer Notional Value % of Total Period
# Filer Notional Value % of Total Period

SPTX Insider Trading (Form 4)

Latest: 2026-11-04
Form 4 filings — insider beneficial-ownership changes by officers, directors, and 10%+ holders. Filed within 2 business days of transaction.
Filed Reporter Role Action Shares Avg Price Net $ Link
2026-11-04 Denice Torres Director Buy (P) +5,000 $19.86 $99.3K EDGAR
2026-06-24 Robert J. Hombach Director Buy (P) +13,000 $18.14 $235.8K EDGAR
2026-05-06 PureTech Health plc 10%+ Owner Conv (C) +16,382,534 — EDGAR
2026-05-04 Sharon Mates Director Grant (A) +49,033 opt — EDGAR
2026-05-04 Steven M Paul Director Conv (C) +67,031 — EDGAR
2026-05-04 Daphne Zohar Chief Executive Officer Grant (A) +1,758,599 opt — EDGAR
2026-05-04 David E. Wheadon Director Grant (A) +12,258 opt — EDGAR
2026-05-04 Sandra E Peterson Director Grant (A) +12,258 opt — EDGAR
2026-05-04 Lana Gladstein General Counsel Conv (C) +33,515 — EDGAR
2026-05-04 Denice Torres Director Conv (C) +13,406 — EDGAR
2026-05-04 Lauren White Chief Financial Officer Conv (C) +6,702 — EDGAR
2026-05-04 Antony Loebel Chief Medical Officer Conv (C) +20,109 — EDGAR
2026-05-04 Michael Cunyuan Chen Chief Scientific Officer Conv (C) +3,351 — EDGAR
2026-05-04 James Healy Director Conv (C) +2,731,538 — EDGAR
2026-05-04 Robert J. Hombach Director Grant (A) +12,258 opt — EDGAR
Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (described in filing footnote — typically 401(k), trust, inheritance) · W = will/inheritance. Only P / S codes carry directional signal.

SPTX Insider Holdings

10 insiders · @ $21.93
Officers, directors, and 10%+ owners who have filed a Form 4 in the past two years, ranked by current disclosed exposure (shares × today's price). Shares are direct + indirect (via trusts / LLCs / spouse). Excludes unvested RSU and option grants — those aren't beneficially owned until vest.
# Insider Role Shares Disclosed Exposure Lifetime OM Net Filings Last Filed
1 PureTech Health plc 10%+ Owner 15,719,758 $344.66M $0 1 2026-05-06
2 James Healy Director 2,731,538 $59.89M $0 1 2026-05-04
3 Steven Gillis 10%+ Owner 2,513,686 $55.11M $19.80M 1 2026-05-04
4 Steven M Paul Director 863,031 $18.92M $0 1 2026-05-04
5 Lana Gladstein General Counsel 33,515 $734.8K $0 1 2026-05-04
6 Antony Loebel Chief Medical Officer 20,109 $440.9K $0 1 2026-05-04
7 Denice Torres Director 18,406 $403.6K $99.3K 2 2026-11-04
8 Robert J. Hombach Director 13,000 $285.0K $235.8K 2 2026-06-24
9 Lauren White Chief Financial Officer 6,702 $146.9K $0 1 2026-05-04
10 Michael Cunyuan Chen Chief Scientific Officer 3,351 $73.5K $0 1 2026-05-04
Lifetime OM Net = signed sum of open-market buys (P) and sells (S) over their career; excludes grants, tax withholdings, and dispositions to issuer. A large negative number is normal for long-tenured executives — they've sold compensation grants over many years.

SPTX Board & Officers

As of SEC filings through Nov 4, 2026

Directors 23

Officers 5

10% owners 21

Changes in the last 10 years (53)
May 6, 2026PureTech LYT, Inc. reported in an SEC filing no longer being a 10% owner
May 6, 2026PureTech Health plc reported in an SEC filing no longer being a 10% owner
May 4, 2026General Atlantic, L.p. became a director
May 4, 2026General Atlantic, L.p. became a 10% owner
May 4, 2026General Atlantic Partners 100, L.P. became a director
May 4, 2026General Atlantic Partners 100, L.P. became a 10% owner
May 4, 2026General Atlantic Partners (Lux), SCSp became a director
May 4, 2026General Atlantic Partners (Lux), SCSp became a 10% owner
May 4, 2026General Atlantic Genpar, L.p. became a director
May 4, 2026General Atlantic Genpar, L.p. became a 10% owner
May 4, 2026General Atlantic Genpar (bermuda), L.p. became a director
May 4, 2026General Atlantic Genpar (bermuda), L.p. became a 10% owner
May 4, 2026General Atlantic (SPV) GP, LLC became a director
May 4, 2026General Atlantic (SPV) GP, LLC became a 10% owner
May 4, 2026General Atlantic (SP), L.P. became a director
May 4, 2026General Atlantic (SP), L.P. became a 10% owner
May 4, 2026General Atlantic (Lux) S.a r.l. became a director
May 4, 2026General Atlantic (Lux) S.a r.l. became a 10% owner
May 4, 2026Gap Coinvestments IV, LLC became a director
May 4, 2026Gap Coinvestments IV, LLC became a 10% owner
Compiled from SEC filings by the company and its directors and officers. Dates are as stated in those filings. Where no filing says when someone left, we show the last filing that listed them.
Recent SEC Filings
Latest: 2026-11-02
Current reports — material events the company must disclose within 4 business days (earnings releases, M&A, executive changes, etc.).
Filing Date Event Link
2026-11-02 Earnings results EDGAR
2026-08-03 Earnings results EDGAR
2026-06-08 Earnings results EDGAR
Annual report — audited financial statements, MD&A, risk factors. Filed 60–90 days after fiscal year-end.
Filing Date Accession Link
Quarterly report — unaudited financials and MD&A. Filed 40–45 days after each of the first three fiscal quarters.
Filing Date Accession Link
2026-11-02 0001193125-26-442634 EDGAR
2026-08-03 0001193125-26-329537 EDGAR
2026-06-08 0001193125-26-260678 EDGAR
ETF Holders
20 ETFs hold SPTX
20 shown · $29.15M total exposure · 0.01% AUM-weighted avg weight
# ETF Provider Weight $ Exposure ETF AUM As Of
1 VTI Vanguard Morningstar Total Stock Market ETF Vanguard 0.00% $8.6M — 2026-09-30
2 IWM iShares Russell 2000 ETF iShares (BlackRock) 0.01% $7.9M $76.6B 2026-11-06
3 VXF Vanguard Extended Market ETF Vanguard 0.00% $3.1M — 2026-09-30
4 IWO iShares Russell 2000 Growth ETF iShares (BlackRock) 0.01% $1.7M $13.7B 2026-11-06
5 VTWO Vanguard Russell 2000 ETF Vanguard 0.01% $1.7M — 2026-09-30
6 SCHA Schwab U.S. Small-Cap ETF Nport 0.01% $1.6M — 2026-08-31
7 SBIO ALPS Medical Breakthroughs ETF Nport 0.65% $1.6M — 2026-08-31
8 IWN iShares Russell 2000 Value ETF iShares (BlackRock) 0.01% $1.2M $13.9B 2026-11-06
9 IWC iShares Micro-Cap ETF iShares (BlackRock) 0.08% $923,941 $1.2B 2026-11-06
10 SCHB Schwab U.S. Broad Market ETF Nport 0.00% $280,205 — 2026-08-31
11 VTWG Vanguard Russell 2000 Growth ETF Vanguard 0.01% $189,215 — 2026-09-30
12 RSSL Global X Russell 2000 ETF Global X 0.01% $144,351 — 2026-11-06
13 VTWV Vanguard Russell 2000 Value ETF Vanguard 0.01% $103,936 — 2026-09-30
14 WCEO Hypatia Women CEO ETF Nport 0.46% $46,178 — 2026-07-31
15 VTHR Vanguard Russell 3000 ETF Vanguard 0.00% $25,112 — 2026-09-30
16 ITWO ProShares Russell 2000 High Income ETF ProShares 0.01% $17,157 — 2026-11-06
17 URTY ProShares UltraPro Russell2000 ProShares 0.01% $13,330 — 2026-11-06
18 UWM ProShares Ultra Russell2000 ProShares 0.00% $9,052 — 2026-11-06
19 HDG ProShares Hedge Replication ETF ProShares 0.00% $387 — 2026-11-06
20 RB ProShares Russell 2000 Dynamic Buffer ETF ProShares 0.01% $108 — 2026-11-06
Fundamentals

Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.

Metrics
  • Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
  • Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
  • Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
  • Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
How to read the bars
  • Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
  • YoY growth — compare to the same quarter a year earlier to remove seasonality.
  • Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
  • Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.

TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.

SPTX vs Peers

Related companies, largest first
Company Market cap P/E Revenue growth YTD IV rank
APGE Apogee Therapeutics, Inc. Common Stock $10.2B — — +78.2% —
CRNX Crinetics Pharmaceuticals, Inc. $9.0B — +2928.4% +81.8% —
ORKA Oruka Therapeutics, Inc. Common Stock $6.8B — — +269.9% 1
CGON CG Oncology, Inc. Common stock $6.7B — +666.0% +78.8% 100
DNTH Dianthus Therapeutics, Inc. Common Stock $4.8B — −60.8% +126.8% 76
TVTX Travere Therapeutics, Inc. Common Stock $4.8B — +49.4% +30.6% 20
XENE Xenon Pharmaceuticals Inc $3.8B — — −9.1% 51
ACAD Acadia Pharmaceuticals Inc. $3.7B 7.4 +11.8% −37.2% 72
SPTX Seaport Therapeutics, Inc. Common Stock $1.2B — — +10.5% —
Peer median $5.8B 7.4 +49.4% +78.5% 62

P/E uses the latest reported trailing-12-month diluted EPS; "—" means no positive earnings or no data.