Bellevue Group AG — 13F Holdings & Portfolio
CIK 1674546 · latest 13F-HR filed 2026-08-14
Bellevue Group AG manages $4.75B in 13F-reported U.S. long-equity assets across 164 reported positions as of its 2026-06-30 13F-HR filing. Its largest disclosed positions are AMGN (6.34%), ARGX (5.88%), VRTX (5.83%). Quarter over quarter (versus its 2026-03-31 filing) the fund opened 17 new positions and exited 24; 70 existing positions rose in reported value and 48 fell.
AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.
Long-equity book
Distinct positions
Filed 2026-08-14
vs 2026-03-31
Portfolio charts
Latest quarter's book, what changed, and how the portfolio has evolved across filings.
| Name | Title / Status | Ownership | Type |
|---|
Quarter-over-quarter changes
Changes in reported position value vs the prior 13F, so price moves count too, not just shares bought or sold.
Top Adds (vs prior quarter)
- AMGEN INC$204.4M +196.7%
- INSMED INC$146.9M +8954.7%
- ORUKA THERAPEUTICS INC$132.8M +534.2%
- GILEAD SCIENCES INC$109.7M +67.3%
- UNITED THERAPEUTICS CORP DEL$100.9M +8193.4%
Top Trims
- REGENERON PHARMACEUTICALS-$117.2M -54.4%
- KRYSTAL BIOTECH INC-$95.6M -76.8%
- ALNYLAM PHARMACEUTICALS INC-$77.3M -99.6%
- IONIS PHARMACEUTICALS INC-$59.5M -43.5%
- BOSTON SCIENTIFIC CORP-$54.2M -58.8%
New Positions
- AVALYN PHARMACEUTICALS INC$44.4M
- CG ONCOLOGY INC$35.1M
- SEAPORT THERAPEUTICS INC$23.9M
- PALVELLA THERAPEUTICS INC NE$23.7M
- SPYRE THERAPEUTICS INC$20.4M
Exited Positions
- EDGEWISE THERAPEUTICS INC$48.1M
- INSPIRE MED SYS INC$5.1M
- PENUMBRA INC$4.0M
- ATRIUM THERAPEUTICS INC$3.5M
- MASIMO CORP$1.6M
Bellevue Group AG Holdings (2026-06-30)
Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).
| # | Issuer | Symbol | CUSIP | Value | Weight | Shares | Type |
|---|---|---|---|---|---|---|---|
| 1 | AMGEN INC | AMGN | 031162100 | $301.1M | 6.34% | 831,588 | SH |
| 2 | ARGENX SE | ARGX | 04016X101 | $279.3M | 5.88% | 301,000 | SH |
| 3 | VERTEX PHARMACEUTICALS INC | VRTX | 92532F100 | $276.9M | 5.83% | 557,375 | SH |
| 4 | GILEAD SCIENCES INC | GILD | 375558103 | $264.4M | 5.56% | 2,093,000 | SH |
| 5 | REVOLUTION MEDICINES INC | RVMD | 76155X100 | $195.2M | 4.11% | 1,042,424 | SH |
| 6 | ORUKA THERAPEUTICS INC | ORKA | 687604108 | $157.7M | 3.32% | 1,657,190 | SH |
| 7 | INSMED INC | INSM | 457669307 | $147.3M | 3.10% | 1,381,740 | SH |
| 8 | SCHOLAR ROCK HLDG CORP | SRRK | 80706P103 | $134.5M | 2.83% | 2,445,032 | SH |
| 9 | NUVALENT INC | NUVL | 670703107 | $130.1M | 2.74% | 1,053,268 | SH |
| 10 | VIRIDIAN THERAPEUTICS INC | VRDN | 92790C104 | $123.4M | 2.60% | 6,717,515 | SH |
| 11 | RELAY THERAPEUTICS INC | RLAY | 75943R102 | $115.7M | 2.43% | 6,184,046 | SH |
| 12 | VAXCYTE INC | PCVX | 92243G108 | $114.4M | 2.41% | 1,967,377 | SH |
| 13 | INTUITIVE SURGICAL INC | ISRG | 46120E602 | $101.3M | 2.13% | 254,809 | SH |
| 14 | UNITED THERAPEUTICS CORP DEL | UTHR | 91307C102 | $98.8M | 2.08% | 182,301 | SH |
| 15 | CRINETICS PHARMACEUTICALS IN | CRNX | 22663K107 | $98.0M | 2.06% | 2,620,000 | SH |
| 16 | REGENERON PHARMACEUTICALS | REGN | 75886F107 | $97.9M | 2.06% | 157,000 | SH |
| 17 | IMMUNOCORE HLDGS PLC | IMCR | 45258D105 | $88.5M | 1.86% | 2,788,245 | SH |
| 18 | BRIDGEBIO PHARMA INC | BBIO | 10806X102 | $87.2M | 1.83% | 1,170,130 | SH |
| 19 | ABBOTT LABORATORIES | ABT | 002824100 | $85.9M | 1.81% | 947,115 | SH |
| 20 | STRYKER CORPORATION | SYK | 863667101 | $84.5M | 1.78% | 268,461 | SH |
| 21 | MEDTRONIC PLC | MDT | G5960L103 | $77.8M | 1.64% | 994,233 | SH |
| 22 | ENLIVEN THERAPEUTICS INC | ELVN | 29337E102 | $75.6M | 1.59% | 1,490,000 | SH |
| 23 | IONIS PHARMACEUTICALS INC | IONS | 462222100 | $74.9M | 1.58% | 944,577 | SH |
| 24 | VERA THERAPEUTICS INC | VERA | 92337R101 | $72.6M | 1.53% | 1,692,906 | SH |
| 25 | JADE BIOSCIENCES INC | JBIO | 008064206 | $67.9M | 1.43% | 3,057,996 | SH |
| 26 | EDWARDS LIFESCIENCES CORP | EW | 28176E108 | $66.9M | 1.41% | 739,234 | SH |
| 27 | ULTRAGENYX PHARMACEUTICAL IN | RARE | 90400D108 | $66.2M | 1.39% | 1,982,775 | SH |
| 28 | UNITEDHEALTH GROUP INC | UNH | 91324P102 | $62.0M | 1.30% | 149,127 | SH |
| 29 | DEXCOM INC | DXCM | 252131107 | $55.4M | 1.17% | 822,489 | SH |
| 30 | CELLDEX THERAPEUTICS INC NEW | CLDX | 15117B202 | $44.7M | 0.94% | 1,200,000 | SH |
| 31 | AVALYN PHARMACEUTICALS INC | AVLN | 05348Y105 | $44.4M | 0.94% | 1,350,000 | SH |
| 32 | DAMORA THERAPEUTICS INC | DMRA | 36322Q206 | $42.1M | 0.89% | 1,618,846 | SH |
| 33 | DISC MEDICINE INC | IRON | 254604101 | $41.0M | 0.86% | 560,000 | SH |
| 34 | THERMO FISHER SCIENTIFIC INC | TMO | 883556102 | $40.0M | 0.84% | 79,816 | SH |
| 35 | BOSTON SCIENTIFIC CORP | BSX | 101137107 | $37.9M | 0.80% | 887,650 | SH |
| 36 | ELI LILLY & CO | LLY | 532457108 | $35.8M | 0.75% | 29,882 | SH |
| 37 | CG ONCOLOGY INC | CGON | 156944100 | $35.1M | 0.74% | 493,596 | SH |
| 38 | IDEXX LABS INC | IDXX | 45168D104 | $32.5M | 0.68% | 61,780 | SH |
| 39 | RESMED INC | RMD | 761152107 | $28.9M | 0.61% | 148,195 | SH |
| 40 | MONTE ROSA THERAPEUTICS INC | GLUE | 61225M102 | $28.8M | 0.61% | 1,190,000 | SH |
| 41 | KRYSTAL BIOTECH INC | KRYS | 501147102 | $28.2M | 0.59% | 76,000 | SH |
| 42 | DANAHER CORP DEL | DHR | 235851102 | $27.4M | 0.58% | 143,844 | SH |
| 43 | JOHNSON & JOHNSON | JNJ | 478160104 | $26.2M | 0.55% | 103,280 | SH |
| 44 | SEAPORT THERAPEUTICS INC | SPTX | 81221K108 | $23.9M | 0.50% | 1,100,000 | SH |
| 45 | PALVELLA THERAPEUTICS INC NE | PVLA | 697947109 | $23.7M | 0.50% | 155,000 | SH |
| 46 | ALIGN TECHNOLOGY INC | ALGN | 016255101 | $23.6M | 0.50% | 139,680 | SH |
| 47 | ANNEXON INC | ANNX | 03589W102 | $23.4M | 0.49% | 4,100,016 | SH |
| 48 | HUMANA INC | HUM | 444859102 | $23.2M | 0.49% | 58,398 | SH |
| 49 | ELEVANCE HEALTH INC FORMERLY | ELV | 036752103 | $21.8M | 0.46% | 56,449 | SH |
| 50 | TANGO THERAPEUTICS INC | TNGX | 87583X109 | $21.7M | 0.46% | 694,182 | SH |
| Period | Filed | AUM | Holdings | Accession |
|---|---|---|---|---|
| 2026-06-30 | 2026-08-14 | $4.75B | 164 | 0001104659-26-096739 |
| 2026-03-31 | 2026-05-15 | $4.20B | 167 | 0001104659-26-061375 |
| 2025-12-31 | 2026-02-17 | $5.28B | 213 | 0001104659-26-016360 |
| 2025-09-30 | 2025-11-14 | $4.81B | 186 | 0001104659-25-112697 |
ZURICH CH-8001