Mereo BioPharma Group plc American Depositary Shares(MREO)
Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership.
Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.
- 52-Week Range
- $0.20 – $2.37
- YTD
- -42.99%
- IV Rank (30D)
- 57.97
- Straddle Price
- $5.38
- P/C Vol Ratio
- 0.23
- Market Cap
- $0.0B
A blended fair-value estimate combining up to six valuation methods. Each method is weighted by how well it fits the company — DCF down-weights for unprofitable names; DDM only fires for steady dividend payers; comparables down-weight when peer multiples disagree.
- DCF (quality-aware) — projects free cash flow with a horizon that scales to business quality. True compounders (quality 6/6) get 10 years explicit + 10 years fade before terminal; cyclical/struggling names (quality 0-1) get a 5-year terminal cliff. Quality is scored from ROE, gross margin, growth, FCF margin, debt load, and FCF consistency — the same factors that drive market premium for compounders.
- Market-Implied Growth (in Model Inputs) — reverse-DCF that answers "what growth rate is the market pricing in?". Lets you sanity-check the deviation: if implied growth is plausible for the business, the model's bearish flag may be wrong; if implausible, the market may be over-extrapolating.
- DDM (Gordon Growth Dividend Model) — values the stream of future dividends. Only used when trailing yield ≥ 2% and dividend payments are stable — below that the dividend is a token payout and Gordon (which values only the dividend stream) systematically underprices growth names, so those route to DCF + comparables + market anchor instead.
- P/E, EV/EBITDA, P/B, P/S — applies the peer-group median multiple to this company's per-share metric. Peers come from the same set as the "Related symbols" card. Earnings/sales metrics are forward-tilted by the company's recent revenue growth (capped at 25%) so they're comparable to peers' growth-embedded multiples — mimics how analysts use NTM rather than TTM. Per-multiple weights are biased by company quality (e.g. P/B down-weighted for asset-light tech).
- Market Anchor (SMA50) — the 50-day moving average, weighted by recent trading-range stability (tighter Bollinger bands → higher weight). Captures information fundamentals miss (forward consensus, sentiment, supply/demand) — but only when recent trading is steady enough that the market has converged on a view. During wild breakouts or breakdowns the anchor's weight collapses.
- Options Expected (B-L 30d) — the risk-neutral expected stock price at 30-day options expiration, derived from the full implied-volatility surface via Breeden-Litzenberger (second derivative of call price wrt strike → implied PDF, then E[S_T]). Forward-looking, captures all options-implied information (smile, skew, term structure) in one number. Weighted by chain liquidity. SP500-only at present (pre-computed daily). Backtest evidence: adds modest alpha across most bucket × holding combos.
- Blended value — weighted average. Confidence reflects how many methods fired and how tight peer dispersion is.
- Deviation pill — green when blended FV ≥ 10% above current price (undervalued); red when ≥ 10% below; grey otherwise.
| 10-yr Treasury (rf) | 4.60% |
| Beta vs SPY | 1.00 |
| Cost of Equity (CAPM) | 10.10% (VRP-adj) |
| WACC | 10.04% |
| Volatility Risk Premium | +422.8pp (IV − HV30), ERP adj +50bps |
| Effective Tax Rate | 21.0% |
| Rev. Growth (YoY, DCF input) | +3.0% |
| DCF Horizon | 5 years explicit + fade |
| Forward Tilt (NTM/TTM) | ×1.03 (applied to P/E, EV/EBITDA, P/S) |
| Quality Score | 0/6 — cyclical/struggling (5y DCF) |
| SMA 50 | $0.30 (Market Anchor value) |
| SMA 20 / Bollinger Mid | $0.32 |
| Bollinger Width / SMA20 | 4839.1% (drives anchor stability) |
| Net Debt | $0.0B |
| Method | Implied Price | Weight | Detail |
|---|---|---|---|
| DCF | n/a | 0% | |
| DDM (Gordon) | n/a | 0% | |
| Peer P/E | n/a | 0% | |
| Peer EV/EBITDA | n/a | 0% | |
| Peer P/B | n/a | 0% | median 5.9× · 6 peers |
| Peer P/S | n/a | 0% | |
| Market Anchor (SMA50) | $0.30 | 0% | stability 0% (BB-width) |
| Options Expected (B-L 30d) | n/a | 0% |
- Industry (SIC)
- PHARMACEUTICAL PREPARATIONS (2834)
- Exchange
- XNAS
- Market Cap
- $0.0B
Mereo BioPharma Group PLC is a United Kingdom (U.K.) based biopharmaceutical company focused on the development of therapeutics for rare diseases. The company has developed a portfolio of late-stage clinical product candidates, and its two rare disease product candidates are setrusumab for the treatment of osteogenesis imperfecta (OI) and alvelestat, mainly for the treatment of severe alpha-1 antitrypsin deficiency-associated lung disease (AATD-LD).
Each spoke is this symbol's rank within its sector (0–100; the dotted ring marks the sector median at 50). Higher is more constructive for a long. One spoke — News sentiment — is an absolute reading, not a sector rank. Grayed spokes have no data. A fuller shape is a summary, not a recommendation.
| Month | Avg Return | Years of Data |
|---|---|---|
| Jan | +5.50% | 6 |
| Feb | -0.14% | 6 |
| Mar | -7.72% | 6 |
| Apr | -2.98% | 6 |
| May | -6.54% | 6 |
| Jun | +27.09% | 6 |
| Jul | -8.24% | 6 |
| Aug | +5.51% | 5 |
| Sep | -7.20% | 5 |
| Oct | +5.75% | 5 |
| Nov | -11.11% | 5 |
| Dec | -21.76% | 5 |
Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.
- SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
- EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
- MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
- ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
- +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
- RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
- Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
- Williams %R — inverted scale: <−80 oversold, >−20 overbought.
Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.
- Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
- OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
- Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
- ATR / True Range — average daily $ move; sizing and stop-loss reference.
- HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.
Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →
Trend Indicators
Momentum Oscillators
Volume & Volatility
Data Summary
Choose Frenzy-Fast™ for quick analysis or Frenzy-Pro™ for comprehensive analysis.
Analysis includes technical indicators, news sentiment, risk assessment, and specific price levels to watch.
| Earnings Date | Timing | Expected Move | Actual Move | Ratio | Outcome |
|---|---|---|---|---|---|
| 2024-08-13 | After-Close | 9.31% | 6.12% | 0.66x | Within |
| 2024-11-12 | After-Close | 14.02% | 1.22% | 0.09x | Within |
| 2025-03-26 | Pre-Market | 106.38% | 0.85% | 0.01x | Within |
| 2025-05-13 | Pre-Market | 66.00% | 7.40% | 0.11x | Within |
| 2025-08-12 | Pre-Market | 337.17% | 9.21% | 0.03x | Within |
| 2025-11-10 | Pre-Market | 16.67% | 1.67% | 0.10x | Within |
| 2026-05-12 | After-Close | 254.07% | 5.49% | 0.02x | Within |
- IV Rank (30D)
- 57.97
- IV Rank (7D)
- 57.97
- Avg IV
- 425.5%
- Straddle (30D)
- $5.38
- Straddle (7D)
- $5.38
- P/C Volume
- 0.23
Each spread is ranked by a composite score built in three stages. Full documentation →
score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.
RR and BF (30-delta) from the persisted per-symbol skew snapshot — wing strikes picked by real greeks.delta, not a moneyness proxy. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.
- RSI <40 bullish / >60 bearish
- MACD crossover + histogram trend
- Price vs SMA 50 & SMA 200
- Stochastic %K <20 / >80
- Williams %R <−80 / >−20
- Blended ATR + straddle expected-move penalty
- Bollinger Band signal (+ counter-trend penalty)
- BB width — vol contraction boost for ICs
- IV rank ≥ 75 → strong boost for credit spreads
- IV rank < 25 → penalty (selling cheap vol)
- Min open interest across all legs
- OI < 100 → −0.10 · OI < 500 → −0.05
score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →
Enter a ticker to scan for optimal spread opportunities.
Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.
IV(put wing) − IV(ATM), in vol pointsHow much the OTM put trades above (or below) the at-the-money strike. Measures the height of the put-side tail relative to ATM — i.e. how expensive crash insurance is on this name.
- Positive (typical) — wing IV > ATM IV. Standard equity put skew: portfolios bid up crash protection, so OTM puts trade richer than ATM.
- Near zero or negative (unusual) — wing IV ≤ ATM IV. Flat or inverted put side. Common when there's no fear demand, in tightly mean-reverting names, or right after an earnings catalyst clears.
- Percentile vs own 3-yr history: high = wings rich (good time to sell wing premium); low = wings cheap (good time to buy protection).
- Not directional — high or low wings don't predict up or down moves. It's a price tag on tail insurance, not a forecast.
IV(call wing) − IV(put wing), equal delta on each sideWhich side of the smile is the market paying up for? Measures the tilt of the surface — call skew vs put skew at matched deltas.
- Negative (typical) — puts richer than calls. Standard equity behavior: hedging demand makes puts carry a premium. Most large-caps sit in the −1 to −5 vol-point range.
- Strongly negative (< −5 pts) — heavy downside hedging, elevated fear, or an upcoming catalyst (earnings, FDA, macro event). Worth flagging.
- Positive — calls richer than puts. Unusual for equities; signals bullish momentum, short-squeeze positioning, or takeover/M&A speculation.
- Near zero — symmetric surface. Market sees roughly equal up/down risk. Rare for large-caps; more common in commodities and FX.
Wing-vs-ATM tells you how expensive the tails are. Risk Reversal tells you which side is favored. Combined:
- High wing percentile + deeply negative RR → strong put bid; stress or major event priced in. Owning protection costs a premium; selling put premium is dangerous.
- Low wing percentile + near-zero RR → complacency; insurance cheap and balanced. Good environment to add cheap downside hedges.
- Positive RR + elevated wings → call-side fear-of-missing-out; common in squeeze setups. Upside calls expensive, downside puts not bid.
Percentile is the rank of today's reading within ~3 years of this symbol's own history. High percentile = wings are rich relative to history; not a directional signal. Skew is read off the chain in real time, not from CBOE SKEW.
Enter a ticker to render the implied volatility surface.
Enter a ticker to render the implied volatility smile.
- Beta (1Y vs SPY)
- 1.59
- Correlation (SPY)
- 15.8%
- R²
- 0.02
- Ann. Volatility
- 127.7%
- SPY Volatility
- 12.7%
High volatility - stock moves more than market
Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.
- Shares — long equity positions in this name, aggregated across share classes.
- Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
- % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
- Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.
Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.
| # | Filer | Notional Value | % of Total | Period |
|---|---|---|---|---|
| 1 | CITADEL ADVISORS LLC Custodian | $127.71K | 40.56% | 2026-03-31 |
| 2 | SUSQUEHANNA INTERNATIONAL GROUP, LLP Custodian | $67.19K | 21.34% | 2026-03-31 |
| 3 | SIMPLEX TRADING, LLC Custodian | $67.02K | 21.28% | 2026-03-31 |
| 4 | JANE STREET GROUP, LLC Custodian | $26.93K | 8.55% | 2026-03-31 |
| 5 | GROUP ONE TRADING LLC Custodian | $26.04K | 8.27% | 2026-03-31 |
| # | Filer | Notional Value | % of Total | Period |
|---|---|---|---|---|
| 1 | GROUP ONE TRADING LLC Custodian | $120.55K | 56.80% | 2026-03-31 |
| 2 | JANE STREET GROUP, LLC Custodian | $37.03K | 17.45% | 2026-03-31 |
| 3 | CITADEL ADVISORS LLC Custodian | $22.37K | 10.54% | 2026-03-31 |
| 4 | SIMPLEX TRADING, LLC Custodian | $17.62K | 8.30% | 2026-03-31 |
| 5 | SUSQUEHANNA INTERNATIONAL GROUP, LLP Custodian | $14.65K | 6.90% | 2026-03-31 |
| Filed | Reporter | Role | Action | Shares | Avg Price | Net $ | Link |
|---|---|---|---|---|---|---|---|
| 2026-02-27 | Annalisa Jenkins | Director | Grant (A) | +172,848 opt | — | EDGAR | |
| 2026-02-27 | DEEPIKA PAKIANATHAN | Director | Grant (A) | +66,000 opt | — | EDGAR | |
| 2026-02-27 | Daniel Shames | Director | Grant (A) | +162,163 opt | — | EDGAR | |
| 2026-02-27 | Anders Ekblom | Director | Grant (A) | +199,560 RSU | — | EDGAR | |
| 2026-02-27 | MICHAEL S WYZGA | Director | Grant (A) | +66,000 opt | — | EDGAR | |
| 2026-02-27 | Pierre Jacquet | Director | Grant (A) | +172,848 opt | — | EDGAR | |
| 2026-02-27 | Jeremy Bender | Director | Grant (A) | +183,533 RSU | — | EDGAR | |
| 2026-02-27 | Marc J Yoskowitz | Director | Grant (A) | +162,163 opt | — | EDGAR | |
| 2026-02-02 | Christine Ann Fox | Chief Financial Officer | Grant (A) | +701,000 opt | — | EDGAR | |
| 2026-02-02 | Charles Sermon | General Counsel | Grant (A) | +716,000 opt | — | EDGAR | |
| 2026-02-02 | Alexandra Hughes-Wilson | See Remarks | Grant (A) | +440,000 opt | — | EDGAR | |
| 2026-02-02 | John A. Lewicki | Chief Scientific Officer | Grant (A) | +331,550 opt | — | EDGAR | |
| 2026-02-02 | Denise Scots-Knight | Chief Executive Officer | Grant (A) | +1,860,000 opt | — | EDGAR | |
| 2025-02-06 | DEEPIKA PAKIANATHAN | Director | Grant (A) | +55,000 opt | — | EDGAR | |
| 2025-02-06 | Anders Ekblom | Director | Grant (A) | +74,054 RSU | — | EDGAR |
| # | Insider | Role | Shares | Disclosed Exposure | Lifetime OM Net | Filings | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Denise Scots-Knight | Chief Executive Officer | 868,967 | $252.9K | -$844.9K | 7 | 2026-02-02 |
| 2 | Charles Sermon | General Counsel | 219,061 | $63.7K | -$294.7K | 7 | 2026-02-02 |
| 3 | Alexandra Hughes-Wilson | See Remarks | 134,483 | $39.1K | -$1.05M | 9 | 2026-02-02 |
| 4 | Christine Ann Fox | Chief Financial Officer | 108,443 | $31.6K | -$269.6K | 7 | 2026-02-02 |
| 5 | DEEPIKA PAKIANATHAN | Director | 105,244 | $30.6K | -$466.2K | 4 | 2026-02-27 |
| 6 | John A. Lewicki | Chief Scientific Officer | 92,826 | $27.0K | -$153.9K | 7 | 2026-02-02 |
| 7 | MICHAEL S WYZGA | Director | 25,050 | $7.3K | $0 | 4 | 2026-02-27 |
| 8 | Jeremy Bender | Director | 12,550 | $3.7K | $0 | 4 | 2026-02-27 |
| # | ETF | Provider | Weight | $ Exposure | ETF AUM | As Of |
|---|
Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.
- Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
- Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
- Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
- Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
- Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
- YoY growth — compare to the same quarter a year earlier to remove seasonality.
- Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
- Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.
TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.