Mereo BioPharma Group plc American Depositary Shares(MREO)

Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership.

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.

Snapshot
$0.30
52-Week Range
$0.20 – $3.05
YTD
-41.99%
IV Rank (30D)
0
Straddle Price
$0.85
P/C Vol Ratio
0.00
Market Cap
$0.0B
Fair Value

A blended fair-value estimate combining up to six valuation methods. Each method is weighted by how well it fits the company — DCF down-weights for unprofitable names; DDM only fires for steady dividend payers; comparables down-weight when peer multiples disagree.

  • DCF (quality-aware) — projects free cash flow with a horizon that scales to business quality. True compounders (quality 6/6) get 10 years explicit + 10 years fade before terminal; cyclical/struggling names (quality 0-1) get a 5-year terminal cliff. Quality is scored from ROE, gross margin, growth, FCF margin, debt load, and FCF consistency — the same factors that drive market premium for compounders.
  • Market-Implied Growth (in Model Inputs) — reverse-DCF that answers "what growth rate is the market pricing in?". Lets you sanity-check the deviation: if implied growth is plausible for the business, the model's bearish flag may be wrong; if implausible, the market may be over-extrapolating.
  • DDM (Gordon Growth Dividend Model) — values the stream of future dividends. Only used when trailing yield ≥ 0.5% and dividend payments are stable.
  • P/E, EV/EBITDA, P/B, P/S — applies the peer-group median multiple to this company's per-share metric. Peers come from the same set as the "Related symbols" card. Earnings/sales metrics are forward-tilted by the company's recent revenue growth (capped at 25%) so they're comparable to peers' growth-embedded multiples — mimics how analysts use NTM rather than TTM. Per-multiple weights are biased by company quality (e.g. P/B down-weighted for asset-light tech).
  • Market Anchor (SMA50) — the 50-day moving average, weighted by recent trading-range stability (tighter Bollinger bands → higher weight). Captures information fundamentals miss (forward consensus, sentiment, supply/demand) — but only when recent trading is steady enough that the market has converged on a view. During wild breakouts or breakdowns the anchor's weight collapses.
  • Options Expected (B-L 30d) — the risk-neutral expected stock price at 30-day options expiration, derived from the full implied-volatility surface via Breeden-Litzenberger (second derivative of call price wrt strike → implied PDF, then E[S_T]). Forward-looking, captures all options-implied information (smile, skew, term structure) in one number. Weighted by chain liquidity. SP500-only at present (pre-computed daily). Backtest evidence: adds modest alpha across most bucket × holding combos.
  • Blended value — weighted average. Confidence reflects how many methods fired and how tight peer dispersion is.
  • Deviation pill — green when blended FV ≥ 10% above current price (undervalued); red when ≥ 10% below; grey otherwise.
10-yr Treasury (rf)4.49%
Beta vs SPY1.00
Cost of Equity (CAPM)9.24% (VRP-adj)
WACC9.82%
Volatility Risk Premium-111.6pp (IV − HV30), ERP adj -25bps
Effective Tax Rate21.0%
Rev. Growth (YoY, DCF input)+3.0%
DCF Horizon5 years explicit + fade
Forward Tilt (NTM/TTM)×1.03 (applied to P/E, EV/EBITDA, P/S)
Quality Score0/6 — cyclical/struggling (5y DCF)
SMA 50$0.30 (Market Anchor value)
SMA 20 / Bollinger Mid$0.29
Bollinger Width / SMA2019401.2% (drives anchor stability)
Net Debt$0.0B
Blended Fair Value
Current Price
$0.31
Deviation
MethodImplied PriceWeightDetail
DCF n/a 0%
DDM (Gordon) n/a 0%
Peer P/E n/a 0%
Peer EV/EBITDA n/a 0%
Peer P/B n/a 0%
Peer P/S n/a 0%
Market Anchor (SMA50) $0.30 0% stability 0% (BB-width)
Options Expected (B-L 30d) n/a 0%
As of 2026-06-08 · updated 2026-06-08 09:31:07.511000
Info
Industry (SIC)
PHARMACEUTICAL PREPARATIONS (2834)
Exchange
XNAS
Market Cap
$0.0B

Mereo BioPharma Group PLC is a United Kingdom (U.K.) based biopharmaceutical company focused on the development of therapeutics for rare diseases. The company has developed a portfolio of late-stage clinical product candidates, and its two rare disease product candidates are setrusumab for the treatment of osteogenesis imperfecta (OI) and alvelestat, mainly for the treatment of severe alpha-1 antitrypsin deficiency-associated lung disease (AATD-LD).

Price History
Seasonality
MonthAvg ReturnYears of Data
Jan +5.50% 6
Feb -0.14% 6
Mar -7.72% 6
Apr -2.98% 6
May -6.54% 6
Jun +26.44% 6
Jul -8.20% 5
Aug +5.51% 5
Sep -7.20% 5
Oct +5.75% 5
Nov -11.11% 5
Dec -21.76% 5
Technical Indicators

Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.

Trend Indicators
  • SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
  • EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
  • MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
  • ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
  • +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
  • RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
  • Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
  • Williams %R — inverted scale: <−80 oversold, >−20 overbought.

Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.

Volume & Volatility
  • Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
  • OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
  • Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
  • ATR / True Range — average daily $ move; sizing and stop-loss reference.
  • HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.

Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →

Trend Indicators
SMA 20: $0.29
SMA 50: $0.30
SMA 200: $1.06
Current: $0.30
EMA 12: $0.31
EMA 26: $0.30
MACD: 0.0090 | Signal: 0.0036
BULLISH
ADX (14): 37.48
TREND
+DI: 18.93
−DI: 13.10
Momentum Oscillators
RSI (14): 50.78
NEUTRAL
Stoch %K: 61.64
Stoch %D: 68.46
Williams %R: -43.43
Volume & Volatility
BB Upper: $0.37
BB Lower: $0.21
NEUTRAL
OBV: -134,083,823
Vol SMA 20: 6,976,930
Vol ROC: 26.88%
ATR: $0.04
True Range: $0.04
HV 20: 114.0%
HV 30: 110.9%
HV 60: 86.6%

Data Summary
Data Points: 500
Last Updated: 2026-06-08T21:15:09.146000
Date Range: 2024-06-10T00:00:00 – 2026-06-08T00:00:00
AI Analysis

Choose Frenzy-Fast™ for quick analysis or Frenzy-Pro™ for comprehensive analysis.

Analysis includes technical indicators, news sentiment, risk assessment, and specific price levels to watch.

News
Options Activity
IV Rank (30D)
0
IV Rank (7D)
34.99
Avg IV
0.2%
Straddle (30D)
$0.85
Straddle (7D)
$10.00
P/C Volume
0.00
Spread Scanner GPU

Each spread is ranked by a composite score built in three stages. Full documentation →

Stage 1 — Base Score (GPU scanner)

score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.

Stage 2 — Skew Adjustment (±25% cap)

RR25 and BF25 from the live options chain. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.

Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
  • RSI <40 bullish / >60 bearish
  • MACD crossover + histogram trend
  • Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
  • Stochastic %K <20 / >80
  • Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
  • Blended ATR + straddle expected-move penalty
  • Bollinger Band signal (+ counter-trend penalty)
  • BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
  • IV rank ≥ 75 → strong boost for credit spreads
  • IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
  • Min open interest across all legs
  • OI < 100 → −0.10 · OI < 500 → −0.05

score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →

Enter a ticker to scan for optimal spread opportunities.

Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.

Volatility Surface

Enter a ticker to render the implied volatility surface.

IV Rank (7 DTE)
IV Rank (30 DTE)
Straddle Price (30 DTE)
Beta Analysis
Beta (1Y vs SPY)
1.62
Correlation (SPY)
14.6%
0.02
Ann. Volatility
133.9%
SPY Volatility
12.1%

High volatility - stock moves more than market

Beta & Alpha Over Time
Institutional Ownership (13F)
Latest filings — 2026-03-31

Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.

  • Shares — long equity positions in this name, aggregated across share classes.
  • Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
  • % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
  • Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.

Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.

65 filers76,654,948 shares$25.35M value
# Filer Shares Value % of Total % of Float Period
1 Rubric Capital Management LP 15,307,347 $5.05M 19.92% 2026-03-31
2 EcoR1 Capital, LLC 13,368,855 $4.41M 17.40% 2026-03-31
3 683 Capital Management, LLC 12,000,000 $3.96M 15.62% 2026-03-31
4 BANK OF AMERICA CORP /DE/ Custodian 8,195,287 $2.70M 10.67% 2026-03-31
5 Defilade Capital Management, L.P. 7,558,756 $2.49M 9.84% 2026-03-31
6 Newtyn Management, LLC 7,079,056 $2.34M 9.21% 2026-03-31
7 MILLENNIUM MANAGEMENT LLC Custodian 3,559,103 $1.17M 4.63% 2026-03-31
8 Tejara Capital Ltd 2,037,520 $672.38K 2.65% 2026-03-31
9 MORGAN STANLEY Custodian 1,273,785 $530.79K 2.09% 2025-12-31
10 UBS Group AG Custodian 1,490,128 $491.74K 1.94% 2026-03-31
11 Wealthspire Advisors, LLC 796,036 $262.69K 1.04% 2026-03-31
12 MARSHALL WACE, LLP Custodian 686,987 $226.71K 0.89% 2026-03-31
13 GROUP ONE TRADING LLC Custodian 335,827 $110.82K 0.44% 2026-03-31
14 Rangeley Capital, LLC 329,200 $108.64K 0.43% 2026-03-31
15 BlackRock, Inc. Custodian 302,991 $99.99K 0.39% 2026-03-31
16 Knott David M Jr 300,337 $99.11K 0.39% 2026-03-31
17 SUSQUEHANNA INTERNATIONAL GROUP, LLP Custodian 195,920 $64.65K 0.26% 2026-03-31
18 TWO SIGMA INVESTMENTS, LP 187,839 $61.99K 0.24% 2026-03-31
19 ADAR1 Capital Management, LLC 150,000 $49.50K 0.20% 2026-03-31
20 JANE STREET GROUP, LLC Custodian 139,973 $46.19K 0.18% 2026-03-31
21 STATE STREET CORP 133,379 $44.02K 0.17% 2026-03-31
22 Forefront Analytics, LLC 127,778 $42.17K 0.17% 2026-03-31
23 Virtus Investment Advisers, LLC 125,662 $41.47K 0.16% 2026-03-31
24 Sheets Smith Investment Management 16,890 $34.79K 0.14% 2025-09-30
25 GEODE CAPITAL MANAGEMENT, LLC Custodian 92,534 $30.54K 0.12% 2026-03-31
5 filers$314.89K notional
# Filer Notional Value % of Total Period
1 CITADEL ADVISORS LLC Custodian $127.71K 40.56% 2026-03-31
2 SUSQUEHANNA INTERNATIONAL GROUP, LLP Custodian $67.19K 21.34% 2026-03-31
3 SIMPLEX TRADING, LLC Custodian $67.02K 21.28% 2026-03-31
4 JANE STREET GROUP, LLC Custodian $26.93K 8.55% 2026-03-31
5 GROUP ONE TRADING LLC Custodian $26.04K 8.27% 2026-03-31
5 filers$212.22K notional
# Filer Notional Value % of Total Period
1 GROUP ONE TRADING LLC Custodian $120.55K 56.80% 2026-03-31
2 JANE STREET GROUP, LLC Custodian $37.03K 17.45% 2026-03-31
3 CITADEL ADVISORS LLC Custodian $22.37K 10.54% 2026-03-31
4 SIMPLEX TRADING, LLC Custodian $17.62K 8.30% 2026-03-31
5 SUSQUEHANNA INTERNATIONAL GROUP, LLP Custodian $14.65K 6.90% 2026-03-31
ETF Holders
# ETF Provider Weight $ Exposure ETF AUM As Of
Fundamentals

Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.

Metrics
  • Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
  • Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
  • Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
  • Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
How to read the bars
  • Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
  • YoY growth — compare to the same quarter a year earlier to remove seasonality.
  • Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
  • Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.

TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.