venBio Partners LLC — 13F Holdings & Portfolio

CIK 1776382 · latest 13F-HR filed 2026-08-14

venBio Partners LLC manages $519.4M in 13F-reported U.S. long-equity assets across 7 reported positions as of its 2026-06-30 13F-HR filing. Its largest disclosed positions are PHVS (30.92%), PBLS (27.75%), ALMS (24.53%). Quarter over quarter (versus its 2026-03-31 filing) the fund opened 2 new positions and exited 1; 3 existing positions rose in reported value and 1 fell.

AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.

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AUM
$519.4M

Long-equity book

Holdings
7

Distinct positions

Period
2026-06-30

Filed 2026-08-14

Q/Q Activity
+2 / −1 / ↑3 / ↓1

vs 2026-03-31

Portfolio charts

Latest quarter's book, what changed, and how the portfolio has evolved across filings.

Firm Profile & Key People
Name Title / Status Ownership Type

Quarter-over-quarter changes

Changes in reported position value vs the prior 13F, so price moves count too, not just shares bought or sold.

Top Adds (vs prior quarter)

Show all 3 →

Top Trims

Show all 1 →

venBio Partners LLC Holdings (2026-06-30)

Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).

# Issuer Symbol CUSIP Value Weight Shares Type
1 PHARVARIS N V PHVS N69605108 $160.6M 30.92% 4,643,430 SH
2 PARABILIS MEDICINES INC PBLS 698955101 $144.1M 27.75% 5,266,697 SH
3 ALUMIS INC ALMS 022307102 $127.4M 24.53% 4,528,408 SH
4 ACHIEVE LIFE SCIENCE INC ACHV 004468500 $38.6M 7.44% 5,914,720 SH
5 ALX ONCOLOGY HLDGS INC ALXO 00166B105 $26.7M 5.14% 12,884,638 SH
6 HARMONY BIOSCIENCES HLDGS IN HRMY 413197104 $17.2M 3.31% 472,194 SH
7 LYELL IMMUNOPHARMA INC LYEL 55083R203 $4.7M 0.91% 337,697 SH
Filing History
Period Filed AUM Holdings Accession
2026-06-30 2026-08-14 $519.4M 7 0000905148-26-003741
2026-03-31 2026-05-15 $280.6M 6 0000905148-26-002409
2025-12-31 2026-02-17 $216.3M 6 0000905148-26-000841
2025-09-30 2025-11-14 $176.4M 6 0000905148-25-004034
Filer Information
Address
1700 OWENS STREET, SUITE 595
SAN FRANCISCO, CA 94158
Phone
(415) 522-0100
Filing Manager
venBio Partners LLC
SAN FRANCISCO, CA
Signatory
David Pezeshki
Chief Financial Officer