Tri Locum Partners LP — 13F Holdings & Portfolio

CIK 1826434 · latest 13F-HR filed 2026-08-14

Tri Locum Partners LP manages $813.2M in 13F-reported U.S. long-equity assets across 19 reported positions as of its 2026-06-30 13F-HR filing. Its largest disclosed positions are JNJ (13.27%), VRTX (12.33%), LLY (11.29%). Quarter over quarter (versus its 2026-03-31 filing) the fund opened 5 new positions, exited 3, added to 9, and trimmed 4.

AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.

Filer Information
Address
287 PARK AVENUE SOUTH, 2ND FLOOR
NEW YORK, NY 10010
Phone
(332) 232-7373
Filing Manager
Tri Locum Partners LP
NEW YORK, NY
Signatory
Christabel Syham
Chief Compliance Officer
Loading holdings…
AUM

$813.2M

Long-equity book

Holdings

19

Distinct positions

Period

2026-06-30

Filed 2026-08-14

Q/Q Activity

+5 / −3 / ↑9 / ↓4

vs 2026-03-31

Firm Profile & Key People
Name Title / Status Ownership Type

Top Adds (vs prior quarter)

  • AXSOME THERAPEUTICS INC.$43.2M +411.3%
  • VERTEX PHARMACEUTICALS INC$42.5M +73.6%
  • ELI LILLY & CO$35.0M +61.5%
  • JAZZ PHARMACEUTICALS PLC$23.4M +78.1%
  • ARGENX SE$15.5M +67.1%
Show all 9 →

Top Trims

  • INTUITIVE SURGICAL INC-$51.6M -73.0%
  • MADRIGAL PHARMACEUTICALS INC-$17.4M -32.2%
  • UNITED THERAPEUTICS CORP DEL-$16.2M -38.9%
  • TEVA PHARMACEUTICAL INDS LTD-$5.4M -17.7%
Show all 4 →

New Positions

  • ASCENDIS PHARMA A/S$69.0M
  • ENLIVEN THERAPEUTICS INC$44.0M
  • REVOLUTION MEDICINES INC$28.4M
  • CYTOKINETICS INC$16.5M
  • BETA BIONICS INC$7.7M
Show all 5 →

Exited Positions

  • THERMO FISHER SCIENTIFIC INC$65.1M
  • ASCENDIS PHARMA A/S$58.4M
  • NUVALENT INC$31.6M
Show all 3 →
All Holdings

Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).

# Issuer Symbol CUSIP Value Weight Shares Type
1 JOHNSON & JOHNSON JNJ 478160104 $107.9M 13.27% 424,945 SH
2 VERTEX PHARMACEUTICALS INC VRTX 92532F100 $100.2M 12.33% 201,791 SH
3 ELI LILLY & CO LLY 532457108 $91.8M 11.29% 76,532 SH
4 ASCENDIS PHARMA A/S ASND K08588103 $69.0M 8.49% 258,740 SH
5 DEXCOM INC DXCM 252131107 $55.3M 6.80% 820,479 SH
6 AXSOME THERAPEUTICS INC. AXSM 05464T104 $53.7M 6.60% 219,308 SH
7 JAZZ PHARMACEUTICALS PLC JAZZ G50871105 $53.4M 6.57% 221,720 SH
8 ENLIVEN THERAPEUTICS INC ELVN 29337E102 $44.0M 5.41% 866,716 SH
9 ARGENX SE ARGX 04016X101 $38.6M 4.75% 41,596 SH
10 MADRIGAL PHARMACEUTICALS INC MDGL 558868105 $36.7M 4.51% 68,273 SH
11 REVOLUTION MEDICINES INC RVMD 76155X100 $28.4M 3.50% 151,822 SH
12 UNITED THERAPEUTICS CORP DEL UTHR 91307C102 $25.5M 3.13% 47,026 SH
13 TEVA PHARMACEUTICAL INDS LTD TEVA 881624209 $25.3M 3.11% 746,835 SH
14 TARSUS PHARMACEUTICALS INC TARS 87650L103 $20.7M 2.54% 328,340 SH
15 INTUITIVE SURGICAL INC ISRG 46120E602 $19.1M 2.35% 47,983 SH
16 CYTOKINETICS INC CYTK 23282W605 $16.5M 2.03% 194,000 SH
17 DIANTHUS THERAPEUTICS INC DNTH 252828108 $11.8M 1.45% 120,712 SH
18 BETA BIONICS INC BBNX 08659B102 $7.7M 0.95% 493,344 SH
19 DEFINIUM THERAPEUTICS INC DFTX 24477V105 $7.7M 0.94% 162,996 SH
Filing History
Period Filed AUM Holdings Accession
2026-06-30 2026-08-14 $813.2M 19 0001826434-26-000005
2026-03-31 2026-05-18 $712.5M 17 0001826434-26-000004
2025-12-31 2026-02-17 $770.1M 15 0001826434-26-000002
2025-09-30 2025-11-14 $435.1M 18 0001826434-25-000008