Checkpoint Capital L.P. — 13F Holdings & Portfolio

CIK 1977548 · latest 13F-HR filed 2026-08-14

Checkpoint Capital L.P. manages $389.8M in 13F-reported U.S. long-equity assets across 6 reported positions as of its 2026-06-30 13F-HR filing. Its largest disclosed positions are RYTM (33.79%), ARGX (31.25%), RVMD (19.72%). Quarter over quarter (versus its 2026-03-31 filing) the fund opened 0 new positions, exited 2, added to 5, and trimmed 0.

AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.

Filer Information
Address
345 CALIFORNIA STREET
SUITE 600
SAN FRANCISCO, CA 94104
Phone
(914) 355-0570
Filing Manager
Checkpoint Capital L.P.
SAN FRANCISCO, CA
Signatory
Sam Huang
Managing Member
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AUM

$389.8M

Long-equity book

Holdings

6

Distinct positions

Period

2026-06-30

Filed 2026-08-14

Q/Q Activity

+0 / −2 / ↑5 / ↓0

vs 2026-03-31

Firm Profile & Key People
Name Title / Status Ownership Type

Top Adds (vs prior quarter)

  • REVOLUTION MEDICINES INC$51.3M +201.0%
  • CYTOKINETICS INC$28.6M +241.1%
  • RHYTHM PHARMACEUTICALS INC$25.0M +23.4%
  • ARGENX SE$10.1M +9.0%
  • TREVI THERAPEUTICS INC$802.2K +134.5%
Show all 5 →

Top Trims

  • No decreased positions.
Show all 0 →

New Positions

  • No new positions this quarter.
Show all 0 →

Exited Positions

  • SEPTERNA INC$2.4M
  • CRINETICS PHARMACEUTICALS IN$1.5M
Show all 2 →
All Holdings

Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).

# Issuer Symbol CUSIP Value Weight Shares Type
1 RHYTHM PHARMACEUTICALS INC RYTM 76243J105 $131.7M 33.79% 1,186,000 SH
2 ARGENX SE ARGX 04016X101 $121.8M 31.25% 131,283 SH
3 REVOLUTION MEDICINES INC RVMD 76155X100 $76.9M 19.72% 410,353 SH
4 CYTOKINETICS INC CYTK 23282W605 $40.5M 10.38% 475,000 SH
5 DISC MEDICINE INC IRON 254604101 $17.6M 4.51% 240,125 SH
6 TREVI THERAPEUTICS INC TRVI 89532M101 $1.4M 0.36% 75,000 SH
Filing History
Period Filed AUM Holdings Accession
2026-06-30 2026-08-14 $389.8M 6 0001977548-26-000005
2026-03-31 2026-05-15 $278.7M 8 0001977548-26-000004
2025-12-31 2026-02-17 $320.1M 7 0001977548-26-000002
2025-09-30 2025-11-14 $298.5M 10 0001977548-25-000008