VYNE Therapeutics Inc. Common Stock(VYNE)

Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership.

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.

VYNE — —
Snapshot
Fair Value

A blended fair-value estimate combining up to six valuation methods. Each method is weighted by how well it fits the company — DCF down-weights for unprofitable names; DDM only fires for steady dividend payers; comparables down-weight when peer multiples disagree.

  • DCF (quality-aware) — projects free cash flow with a horizon that scales to business quality. True compounders (quality 6/6) get 10 years explicit + 10 years fade before terminal; cyclical/struggling names (quality 0-1) get a 5-year terminal cliff. Quality is scored from ROE, gross margin, growth, FCF margin, debt load, and FCF consistency — the same factors that drive market premium for compounders.
  • Market-Implied Growth (in Model Inputs) — reverse-DCF that answers "what growth rate is the market pricing in?". Lets you sanity-check the deviation: if implied growth is plausible for the business, the model's bearish flag may be wrong; if implausible, the market may be over-extrapolating.
  • DDM (Gordon Growth Dividend Model) — values the stream of future dividends. Only used when trailing yield ≥ 2% and dividend payments are stable — below that the dividend is a token payout and Gordon (which values only the dividend stream) systematically underprices growth names, so those route to DCF + comparables + market anchor instead.
  • P/E, EV/EBITDA, P/B, P/S — applies the peer-group median multiple to this company's per-share metric. Peers come from the same set as the "Related symbols" card. Earnings/sales metrics are forward-tilted by the company's recent revenue growth (capped at 25%) so they're comparable to peers' growth-embedded multiples — mimics how analysts use NTM rather than TTM. Per-multiple weights are biased by company quality (e.g. P/B down-weighted for asset-light tech).
  • Market Anchor (SMA50) — the 50-day moving average, weighted by recent trading-range stability (tighter Bollinger bands → higher weight). Captures information fundamentals miss (forward consensus, sentiment, supply/demand) — but only when recent trading is steady enough that the market has converged on a view. During wild breakouts or breakdowns the anchor's weight collapses.
  • Options Expected (B-L 30d) — the risk-neutral expected stock price at 30-day options expiration, derived from the full implied-volatility surface via Breeden-Litzenberger (second derivative of call price wrt strike → implied PDF, then E[S_T]). Forward-looking, captures all options-implied information (smile, skew, term structure) in one number. Weighted by chain liquidity. SP500-only at present (pre-computed daily). Backtest evidence: adds modest alpha across most bucket × holding combos.
  • Blended value — weighted average. Confidence reflects how many methods fired and how tight peer dispersion is.
  • Deviation pill — green when blended FV ≥ 10% above current price (undervalued); red when ≥ 10% below; grey otherwise.
10-yr Treasury (rf)4.71%
Beta vs SPY1.00
Cost of Equity (CAPM)9.71%
WACC9.63%
Effective Tax Rate21.0%
Rev. Growth (YoY, DCF input)-10.0%
DCF Horizon10 years explicit + fade
Free Cash Flow (TTM)$-0.0B
Return on Equity (TTM)-72.9%
Gross Margin (TTM)100.0%
FCF Margin (TTM)-10523.5%
Debt / Equity0.00
Quality Score2/6 — normal (10y DCF)
SMA 50$34.07 (Market Anchor value)
SMA 20 / Bollinger Mid$35.53
Bollinger Width / SMA20165.0% (drives anchor stability)
Net Debt$-0.0B
Peers used for multiples: ABT, PFE, REGN (SIC-code peers; ETF co-membership was sector-incoherent)
Blended Fair Value
—
Deviation
—
MethodImplied PriceWeightDetail
DCF n/a 0%
DDM (Gordon) $1.84 0%
Peer P/E n/a 0% median 18.7× · 3 peers
Peer EV/EBITDA n/a 0% median 16.5× · 3 peers
Peer P/B n/a 0% median 2.2× · 3 peers
Peer P/S n/a 0% median 4.0× · 3 peers
Market Anchor (SMA50) $34.07 0% stability 0% (BB-width)
Options Expected (B-L 30d) n/a 0%
As of 2026-07-28 · updated
Info
Industry (SIC)
PHARMACEUTICAL PREPARATIONS (2834)
Exchange
XNAS
Market Cap
$0.0B

VYNE Therapeutics Inc is a biopharmaceutical company focused on developing proprietary and differentiated therapies for the treatment of immuno-inflammatory conditions. The company is also in the pre-clinical stages of research, develop and commercialize products containing small molecule bromodomain and extra-terminal domain (BET) inhibitors for the treatment of any disease, disorder or condition in human. Its products include AMZEEQ, ZILXI, and FCD105.

Summary
—
composite
—
No summary data available for this symbol yet.

Each spoke is this symbol's rank within its sector (0–100; the dotted ring marks the sector median at 50). Higher is more constructive for a long. One spoke — News sentiment — is an absolute reading, not a sector rank. Grayed spokes have no data. A fuller shape is a summary, not a recommendation.

Chart
Seasonality
MonthAvg ReturnYears of Data
Jan -0.21% 6
Feb -1.32% 6
Mar +0.01% 6
Apr -4.14% 6
May -4.69% 6
Jun -1.63% 6
Jul -16.54% 6
Aug -15.96% 5
Sep -3.58% 6
Oct +6.92% 6
Nov -1.23% 6
Dec -1.97% 6
Technical Indicators

Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.

Trend Indicators
  • SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
  • EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
  • MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
  • ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
  • +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
  • RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
  • Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
  • Williams %R — inverted scale: <−80 oversold, >−20 overbought.

Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.

Volume & Volatility
  • Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
  • OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
  • Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
  • ATR / True Range — average daily $ move; sizing and stop-loss reference.
  • HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.

Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →

Trend Indicators

SMA 20: $35.53
SMA 50: $34.07
SMA 200: $28.15
Current: $28.56
EMA 12: $36.11
EMA 26: $35.39
MACD: 0.7217 | Signal: -0.6762
BULLISH
ADX (14): 32.17
TREND
+DI: 18.38
−DI: 34.94

Momentum Oscillators

RSI (14): 39.73
NEUTRAL
Stoch %K: 41.85
Stoch %D: 68.21
Williams %R: -77.99

Volume & Volatility

BB Upper: $45.95
BB Lower: $25.11
NEUTRAL
OBV: 4,846,886
Vol SMA 20: 44,267
Vol ROC: 58.02%
ATR: $4.10
True Range: $5.19
HV 20: 230.3%
HV 30: 187.2%
HV 60: 132.0%

Data Summary

Data Points: 500
Last Updated:
Date Range: 2024-07-29T00:00:00 – 2026-07-27T00:00:00
AI Analysis

Click Frenzy-Pro™ for an AI analysis of this ticker.

Analysis includes technical indicators, news sentiment, risk assessment, and specific price levels to watch.

News
Options Activity
IV Rank (30D)
0
IV Rank (7D)
0
Avg IV
0.0%
Spread Scanner GPU

Each spread is ranked by a composite score built in three stages. Full documentation →

Stage 1 — Base Score (GPU scanner)

score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.

Stage 2 — Skew Adjustment (±25% cap)

RR and BF (30-delta) from the persisted per-symbol skew snapshot — wing strikes picked by real greeks.delta, not a moneyness proxy. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.

Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
  • RSI <40 bullish / >60 bearish
  • MACD crossover + histogram trend
  • Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
  • Stochastic %K <20 / >80
  • Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
  • Blended ATR + straddle expected-move penalty
  • Bollinger Band signal (+ counter-trend penalty)
  • BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
  • IV rank ≥ 75 → strong boost for credit spreads
  • IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
  • Min open interest across all legs
  • OI < 100 → −0.10 · OI < 500 → −0.05

score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →

Enter a ticker to scan for optimal spread opportunities.

Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.

Skew (Wing IV − ATM IV)
DTE:
Wing Δ:
Metric:
Wing vs ATM
IV(put wing) − IV(ATM), in vol points

How much the OTM put trades above (or below) the at-the-money strike. Measures the height of the put-side tail relative to ATM — i.e. how expensive crash insurance is on this name.

  • Positive (typical) — wing IV > ATM IV. Standard equity put skew: portfolios bid up crash protection, so OTM puts trade richer than ATM.
  • Near zero or negative (unusual) — wing IV ≤ ATM IV. Flat or inverted put side. Common when there's no fear demand, in tightly mean-reverting names, or right after an earnings catalyst clears.
  • Percentile vs own 3-yr history: high = wings rich (good time to sell wing premium); low = wings cheap (good time to buy protection).
  • Not directional — high or low wings don't predict up or down moves. It's a price tag on tail insurance, not a forecast.
Risk Reversal
IV(call wing) − IV(put wing), equal delta on each side

Which side of the smile is the market paying up for? Measures the tilt of the surface — call skew vs put skew at matched deltas.

  • Negative (typical) — puts richer than calls. Standard equity behavior: hedging demand makes puts carry a premium. Most large-caps sit in the −1 to −5 vol-point range.
  • Strongly negative (< −5 pts) — heavy downside hedging, elevated fear, or an upcoming catalyst (earnings, FDA, macro event). Worth flagging.
  • Positive — calls richer than puts. Unusual for equities; signals bullish momentum, short-squeeze positioning, or takeover/M&A speculation.
  • Near zero — symmetric surface. Market sees roughly equal up/down risk. Rare for large-caps; more common in commodities and FX.
Reading them together

Wing-vs-ATM tells you how expensive the tails are. Risk Reversal tells you which side is favored. Combined:

  • High wing percentile + deeply negative RR → strong put bid; stress or major event priced in. Owning protection costs a premium; selling put premium is dangerous.
  • Low wing percentile + near-zero RR → complacency; insurance cheap and balanced. Good environment to add cheap downside hedges.
  • Positive RR + elevated wings → call-side fear-of-missing-out; common in squeeze setups. Upside calls expensive, downside puts not bid.
14 DTE / 10d —
— pts EXTREME
ATM — / Wing —
30 DTE / 10d —
— pts EXTREME
ATM — / Wing —

Percentile is the rank of today's reading within ~3 years of this symbol's own history. High percentile = wings are rich relative to history; not a directional signal. Skew is read off the chain in real time, not from CBOE SKEW.

Volatility Surface

Enter a ticker to render the implied volatility surface.

Volatility Smile

Enter a ticker to render the implied volatility smile.

IV Rank (7 DTE)
IV Rank (30 DTE)
Straddle Price (30 DTE)
Beta Analysis
Beta (1Y vs SPY)
0.14
Correlation (SPY)
2.1%
R²
0.00
Ann. Volatility
89.7%
SPY Volatility
13.3%

Low volatility - stock moves less than market

Beta & Alpha Over Time
Institutional Ownership (13F)
Latest filings — 2026-06-30
Diluted shares outstanding: 42,742,000 (as of 2026-03-31)

Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.

  • Shares — long equity positions in this name, aggregated across share classes.
  • Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
  • % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
  • Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.

Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.

50 filers14,830,137 shares$9.24M value34.70% of float
# Filer Shares Value % of Total % of Float Period
1 ADAR1 Capital Management, LLC 2,950,000 $1.92M 20.78% 6.90% 2026-06-30
2 Nantahala Capital Management, LLC 2,000,000 $1.30M 14.09% 4.68% 2026-06-30
3 Lynx1 Capital Management LP 1,628,700 $1.06M 11.47% 3.81% 2026-06-30
4 Shay Capital LLC 1,456,651 $947.84K 10.26% 3.41% 2026-06-30
5 T3 Companies, LLC 945,000 $614.91K 6.66% 2.21% 2026-06-30
6 BRAIDWELL LP 916,077 $596.09K 6.45% 2.14% 2026-06-30
7 Deeter Investments LLP 1,000,000 $580.10K 6.28% 2.34% 2025-12-31
8 KVP Capital Advisors, LP 500,551 $325.71K 3.53% 1.17% 2026-06-30
9 CITADEL ADVISORS LLC Custodian 468,457 $304.82K 3.30% 1.10% 2026-06-30
10 TWO SIGMA INVESTMENTS, LP Custodian 438,818 $285.54K 3.09% 1.03% 2026-06-30
11 VANGUARD GROUP INC Custodian 314,545 $182.44K 1.97% 0.74% 2025-12-31
12 Ikarian Capital, LLC 264,912 $172.38K 1.87% 0.62% 2026-06-30
13 VANGUARD CAPITAL MANAGEMENT LLC 264,557 $172.23K 1.86% 0.62% 2026-06-30
14 GEODE CAPITAL MANAGEMENT, LLC Custodian 258,203 $168.02K 1.82% 0.60% 2026-06-30
15 VANGUARD FIDUCIARY TRUST CO 183,443 $119.42K 1.29% 0.43% 2026-06-30
16 SUSQUEHANNA INTERNATIONAL GROUP, LLP Custodian 118,957 $77.41K 0.84% 0.28% 2026-06-30
17 Rangeley Capital, LLC 113,064 $73.57K 0.80% 0.26% 2026-06-30
18 XTX Topco Ltd 78,721 $51.22K 0.55% 0.18% 2026-06-30
19 SUPERSTRING CAPITAL MANAGEMENT LP 61,269 $39.87K 0.43% 0.14% 2026-06-30
20 UBS Group AG Custodian 58,597 $38.15K 0.41% 0.14% 2026-06-30
21 STALEY CAPITAL ADVISERS INC 51,472 $33.49K 0.36% 0.12% 2026-06-30
22 BlackRock, Inc. Custodian 44,405 $28.89K 0.31% 0.10% 2026-06-30
23 NORTHERN TRUST CORP Custodian 43,677 $28.42K 0.31% 0.10% 2026-06-30
24 JANE STREET GROUP, LLC Custodian 40,974 $26.66K 0.29% 0.10% 2026-06-30
25 TWO SIGMA SECURITIES, LLC 40,697 $26.48K 0.29% 0.10% 2026-06-30
# Filer Notional Value % of Total Period
# Filer Notional Value % of Total Period
Insider Activity
Latest: 2026-07-24
Form 4 filings — insider beneficial-ownership changes by officers, directors, and 10%+ holders. Filed within 2 business days of transaction.
Filed Reporter Role Action Shares Avg Price Net $ Link
2026-07-24 Iain Stuart CHIEF SCIENTIFIC OFFICER Tax (F) −15,405 $0.90 -$13.8K EDGAR
2026-07-24 Mutya Harsch CHIEF LEGAL OFFICER AND GC Tax (F) −22,516 $0.90 -$20.2K EDGAR
2026-07-24 Tyler Zeronda CHIEF FINANCIAL OFFICER Tax (F) −22,516 $0.90 -$20.2K EDGAR
2026-07-24 David Domzalski PRESIDENT AND CEO Tax (F) −79,391 $0.90 -$71.3K EDGAR
2026-07-02 Iain Stuart CHIEF SCIENTIFIC OFFICER Tax (F) −2,370 $0.65 -$1.5K EDGAR
2026-07-02 Mutya Harsch CHIEF LEGAL OFFICER AND GC Tax (F) −3,464 $0.65 -$2.3K EDGAR
2026-07-02 David Domzalski PRESIDENT AND CEO Tax (F) −12,214 $0.65 -$7.9K EDGAR
2026-07-02 Tyler Zeronda CHIEF FINANCIAL OFFICER Tax (F) −3,464 $0.65 -$2.3K EDGAR
2026-06-02 David Domzalski PRESIDENT AND CEO Award (A) +30,791 $0.31 $9.5K EDGAR
2026-04-02 Tyler Zeronda CHIEF FINANCIAL OFFICER Tax (F) −4,007 $0.60 -$2.4K EDGAR
2026-04-02 David Domzalski PRESIDENT AND CEO Tax (F) −14,232 $0.60 -$8.5K EDGAR
2026-04-02 Mutya Harsch CHIEF LEGAL OFFICER AND GC Tax (F) −4,007 $0.60 -$2.4K EDGAR
2026-04-02 Iain Stuart CHIEF SCIENTIFIC OFFICER Tax (F) −2,876 $0.60 -$1.7K EDGAR
2026-01-05 Iain Stuart CHIEF SCIENTIFIC OFFICER Tax (F) −2,448 $0.58 -$1.4K EDGAR
2026-01-05 David Domzalski PRESIDENT AND CEO Tax (F) −12,684 $0.58 -$7.4K EDGAR
Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (described in filing footnote — typically 401(k), trust, inheritance) · W = will/inheritance. Only P / S codes carry directional signal.
Insider Holdings
8 insiders · @ $28.56
Officers, directors, and 10%+ owners ranked by current disclosed exposure (shares × today's price). Shares are direct + indirect (via trusts / LLCs / spouse). Excludes unvested RSU and option grants — those aren't beneficially owned until vest.
# Insider Role Shares Disclosed Exposure Lifetime OM Net Filings Last Filed
1 David Domzalski PRESIDENT AND CEO 6,943 $198.3K $103.6K 42 2026-07-24
2 JOSEPH EDELMAN 10%+ Owner 5,483 $156.6K $14.04M 5 2021-08-18
3 Iain Stuart CHIEF SCIENTIFIC OFFICER 1,919 $54.8K $0 30 2026-07-24
4 Mutya Harsch CHIEF LEGAL OFFICER AND GC 1,918 $54.8K $25.0K 34 2026-07-24
5 Tyler Zeronda CHIEF FINANCIAL OFFICER 1,498 $42.8K $0 28 2026-07-24
6 PATRICK G LEPORE Director 1,029 $29.4K $399.9K 15 2025-12-15
7 Andrew Saik Chief Financial Officer 129 $3.7K $58.5K 4 2021-06-02
8 Matthew T. Wiley Chief Commercial Officer 121 $3.5K $0 6 2021-07-02
Lifetime OM Net = signed sum of open-market buys (P) and sells (S) over their career; excludes grants, tax withholdings, and dispositions to issuer. A large negative number is normal for long-tenured executives — they've sold compensation grants over many years.
ETF Holders
# ETF Provider Weight $ Exposure ETF AUM As Of
Fundamentals

Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.

Metrics
  • Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
  • Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
  • Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
  • Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
How to read the bars
  • Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
  • YoY growth — compare to the same quarter a year earlier to remove seasonality.
  • Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
  • Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.

TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.

P/B Ratio0.8
P/S Ratio53.4
EV/EBITDA0.3
TTM Revenue$0.0B
TTM Net Income$-0.0B
TTM EPS$-0.41
ROE-72.9%