Patient Square Capital LP — 13F Holdings & Portfolio
CIK 1819257 · latest 13F-HR filed 2026-05-15
Patient Square Capital LP manages $563.6M in 13F-reported U.S. long-equity assets across 29 reported positions as of its 2026-03-31 13F-HR filing. Its largest disclosed positions are ROIV (40.13%), ARGX (4.76%), INSM (4.57%). Quarter over quarter (versus its 2025-12-31 filing) the fund opened 7 new positions, exited 6, added to 12, and trimmed 9.
AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.
$563.6M
Long-equity book
29
Distinct positions
2026-03-31
Filed 2026-05-15
+7 / −6 / ↑12 / ↓9
vs 2025-12-31
| Name | Title / Status | Ownership | Type |
|---|
Top Adds (vs prior quarter)
- ROIVANT SCIENCES LTD$49.0M +27.6%
- COGENT BIOSCIENCES INC$11.7M +103.5%
- DBV TECHNOLOGIES S A$7.6M +110.5%
- XENON PHARMACEUTICALS INC$7.1M +115.8%
- HARROW INC$5.5M +1590.8%
Top Trims
- INSMED INC-$20.7M -44.6%
- SPYRE THERAPEUTICS INC-$4.9M -99.0%
- ABIVAX SA-$4.0M -23.0%
- EYEPOINT INC-$4.0M -28.1%
- KYMERA THERAPEUTICS INC-$2.5M -23.0%
New Positions
- BELITE BIO INC$18.6M
- LEGEND BIOTECH CORP$17.9M
- NEKTAR THERAPEUTICS$15.1M
- MERCK & CO INC$9.6M
- DEFINIUM THERAPEUTICS INC$6.3M
Exited Positions
- TERNS PHARMACEUTICALS INC$12.9M
- LIQUIDIA CORPORATION$7.8M
- OCULAR THERAPEUTIX INC$5.9M
- DISC MEDICINE INC$5.9M
- AVALO THERAPEUTICS INC$5.7M
Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).
| # | Issuer | Symbol | CUSIP | Value | Weight | Shares | Type |
|---|---|---|---|---|---|---|---|
| 1 | ROIVANT SCIENCES LTD | ROIV | G76279101 | $226.2M | 40.13% | 8,166,047 | SH |
| 2 | ARGENX SE | ARGX | 04016X101 | $26.8M | 4.76% | 36,718 | SH |
| 3 | INSMED INC | INSM | 457669307 | $25.8M | 4.57% | 157,500 | SH |
| 4 | BEONE MEDICINES LTD | ONC | 07725L102 | $23.9M | 4.24% | 80,542 | SH |
| 5 | COGENT BIOSCIENCES INC | COGT | 19240Q201 | $22.9M | 4.07% | 596,000 | SH |
| 6 | MIRUM PHARMACEUTICALS INC | MIRM | 604749101 | $21.2M | 3.77% | 230,000 | SH |
| 7 | BELITE BIO INC | BLTE | 07782B104 | $18.6M | 3.30% | 116,684 | SH |
| 8 | LEGEND BIOTECH CORP | LEGN | 52490G102 | $17.9M | 3.18% | 990,000 | SH |
| 9 | NEKTAR THERAPEUTICS | NKTR | 640268306 | $15.1M | 2.68% | 210,000 | SH |
| 10 | DBV TECHNOLOGIES S A | DBVT | 23306J309 | $14.5M | 2.57% | 693,534 | SH |
| 11 | PHARVARIS N V | PHVS | N69605108 | $13.9M | 2.47% | 493,000 | SH |
| 12 | ABIVAX SA | ABVX | 00370M103 | $13.5M | 2.40% | 121,245 | SH |
| 13 | XENON PHARMACEUTICALS INC | XENE | 98420N105 | $13.2M | 2.34% | 227,000 | SH |
| 14 | CELCUITY INC | CELC | 15102K100 | $10.8M | 1.92% | 95,000 | SH |
| 15 | EYEPOINT INC | EYPT | 30233G209 | $10.2M | 1.82% | 795,000 | SH |
| 16 | MERCK & CO INC | MRK | 58933Y105 | $9.6M | 1.71% | 80,000 | SH |
| 17 | ARCUTIS BIOTHERAPEUTICS INC | ARQT | 03969K108 | $9.4M | 1.67% | 400,645 | SH |
| 18 | ALLOGENE THERAPEUTICS INC | ALLO | 019770106 | $8.4M | 1.49% | 3,450,000 | SH |
| 19 | KYMERA THERAPEUTICS INC | KYMR | 501575104 | $8.3M | 1.48% | 100,000 | SH |
| 20 | DIANTHUS THERAPEUTICS INC | DNTH | 252828108 | $7.9M | 1.40% | 93,882 | SH |
| 21 | ENLIVEN THERAPEUTICS INC | ELVN | 29337E102 | $7.8M | 1.39% | 200,000 | SH |
| 22 | PERSPECTIVE THERAPEUTICS INC | CATX | 46489V302 | $6.8M | 1.20% | 1,625,000 | SH |
| 23 | DEFINIUM THERAPEUTICS INC | DFTX | 24477V105 | $6.3M | 1.11% | 331,000 | SH |
| 24 | HARROW INC | HROW | 415858109 | $5.8M | 1.03% | 165,209 | SH |
| 25 | PROTARA THERAPEUTICS INC | TARA | 74365U107 | $5.4M | 0.95% | 1,030,846 | SH |
| 26 | CYTOMX THERAPEUTICS INC. | CTMX | 23284F105 | $5.1M | 0.91% | 1,085,790 | SH |
| 27 | ARCUS BIOSCIENCES INC | RCUS | 03969F109 | $4.2M | 0.75% | 195,000 | SH |
| 28 | ASSEMBLY BIOSCIENCES INC | ASMB | 045396207 | $3.8M | 0.67% | 136,315 | SH |
| 29 | SPYRE THERAPEUTICS INC | SYRE | 00773J202 | $50.4K | 0.01% | 1,000 | SH |
| Period | Filed | AUM | Holdings | Accession |
|---|---|---|---|---|
| 2026-03-31 | 2026-05-15 | $563.6M | 29 | 0001819257-26-000003 |
| 2025-12-31 | 2026-02-12 | $467.1M | 28 | 0001819257-26-000002 |
| 2025-09-30 | 2025-11-10 | $373.9M | 24 | 0001819257-25-000002 |