Pivotal bioVenture Partners Investment Advisor LLC — 13F Holdings & Portfolio

CIK 1844645 · latest 13F-HR filed 2026-08-13

Pivotal bioVenture Partners Investment Advisor LLC manages $307.8M in 13F-reported U.S. long-equity assets across 13 reported positions as of its 2026-06-30 13F-HR filing. Its largest disclosed positions are PCVX (26.92%), ARQT (10.78%), TRVI (10.56%). Quarter over quarter (versus its 2026-03-31 filing) the fund opened 1 new position and exited 1; 7 existing positions rose in reported value and 2 fell.

AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.

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AUM
$307.8M

Long-equity book

Holdings
13

Distinct positions

Period
2026-06-30

Filed 2026-08-13

Q/Q Activity
+1 / −1 / ↑7 / ↓2

vs 2026-03-31

Portfolio charts

Latest quarter's book, what changed, and how the portfolio has evolved across filings.

Firm Profile & Key People
Name Title / Status Ownership Type

Quarter-over-quarter changes

Changes in reported position value vs the prior 13F, so price moves count too, not just shares bought or sold.

Top Adds (vs prior quarter)

Show all 7 →

Top Trims

Show all 2 →

Exited Positions

Show all 1 →

Pivotal bioVenture Partners Investment Advisor LLC Holdings (2026-06-30)

Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).

# Issuer Symbol CUSIP Value Weight Shares Type
1 VAXCYTE INC PCVX 92243G108 $82.9M 26.92% 1,425,470 SH
2 ARCUTIS BIOTHERAPEUTICS INC ARQT 03969K108 $33.2M 10.78% 1,265,283 SH
3 TREVI THERAPEUTICS INC TRVI 89532M101 $32.5M 10.56% 1,742,672 SH
4 AVALYN PHARMACEUTICALS INC AVLN 05348Y105 $31.8M 10.34% 966,792 SH
5 EVOMMUNE INC EVMN 30054Y107 $25.6M 8.32% 1,926,943 SH
6 MAPLIGHT THERAPEUTICS INC MPLT 56565P103 $21.9M 7.12% 611,446 SH
7 OCULIS HOLDING AG OCS H5870P102 $20.9M 6.79% 1,506,250 SH
8 BIOAGE LABS INC BIOA 09077V100 $16.0M 5.20% 653,374 SH
9 IMMUNOME INC IMNM 45257U108 $15.5M 5.04% 732,512 SH
10 ZENAS BIOPHARMA INC ZBIO 98937L105 $12.5M 4.05% 490,766 SH
11 AVALO THERAPEUTICS INC AVTX 05338F306 $8.0M 2.61% 434,033 SH
12 RALLYBIO CORP RLYB 75120L209 $4.8M 1.56% 300,579 SH
13 RECURSION PHARMACEUTICALS IN RXRX 75629V104 $2.2M 0.71% 595,518 SH
Filing History
Period Filed AUM Holdings Accession
2026-06-30 2026-08-13 $307.8M 13 0001012975-26-000759
2026-03-31 2026-05-14 $279.8M 13 0001012975-26-000421
2025-12-31 2026-02-13 $258.7M 12 0001012975-26-000133
2025-09-30 2025-11-13 $173.0M 10 0001012975-25-000748
Filer Information
Address
501 2ND ST, SUITE 200
SAN FRANCISCO, CA 94107
Phone
(415) 948-7474
Filing Manager
Pivotal bioVenture Partners Investment Advisor LLC
SAN FRANCISCO, CA
Signatory
Robert Hopfner
Managing Partner