AVTX Avalo Therapeutics, Inc. Common Stock

XNAS 6.77 Delayed
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Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership. Iron condor setups Expected move IV rank history Fibonacci levels Insider trading

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.

AVTX $6.77 —
Key stats
$6.77
Pre-market $6.81 +0.59%
52-Week Range
$6.53 – $24.27
YTD
-60.22%
IV Rank (30D)
14.35
Straddle Price
$1.28
P/C Vol Ratio
1.45
Market Cap
$0.4B
Open
$6.82
Day Range
$6.56 – $7.13
Volume
2,370,681
Prev Close
$6.93
Fair Value
+50.0% vs price

A blended fair-value estimate combining up to six valuation methods. Each method is weighted by how well it fits the company — DCF down-weights for unprofitable names; DDM only fires for steady dividend payers; comparables down-weight when peer multiples disagree.

  • DCF (quality-aware) — projects free cash flow with a horizon that scales to business quality. True compounders (quality 6/6) get 10 years explicit + 10 years fade before terminal; cyclical/struggling names (quality 0-1) get a 5-year terminal cliff. Quality is scored from ROE, gross margin, growth, FCF margin, debt load, and FCF consistency — the same factors that drive market premium for compounders.
  • Market-Implied Growth (in Model Inputs) — reverse-DCF that answers "what growth rate is the market pricing in?". Lets you sanity-check the deviation: if implied growth is plausible for the business, the model's bearish flag may be wrong; if implausible, the market may be over-extrapolating.
  • DDM (Gordon Growth Dividend Model) — values the stream of future dividends. Only used when trailing yield ≥ 2% and dividend payments are stable — below that the dividend is a token payout and Gordon (which values only the dividend stream) systematically underprices growth names, so those route to DCF + comparables + market anchor instead.
  • P/E, EV/EBITDA, P/B, P/S — applies the peer-group median multiple to this company's per-share metric. Peers come from the same set as the "Related symbols" card. Earnings/sales metrics are forward-tilted by the company's recent revenue growth (capped at 25%) so they're comparable to peers' growth-embedded multiples — mimics how analysts use NTM rather than TTM. Per-multiple weights are biased by company quality (e.g. P/B down-weighted for asset-light tech).
  • Market Anchor (SMA50) — the 50-day moving average, weighted by recent trading-range stability (tighter Bollinger bands → higher weight). Captures information fundamentals miss (forward consensus, sentiment, supply/demand) — but only when recent trading is steady enough that the market has converged on a view. During wild breakouts or breakdowns the anchor's weight collapses.
  • Options Expected (B-L 30d) — the risk-neutral expected stock price at 30-day options expiration, derived from the full implied-volatility surface via Breeden-Litzenberger (second derivative of call price wrt strike → implied PDF, then E[S_T]). Forward-looking, captures all options-implied information (smile, skew, term structure) in one number. Weighted by chain liquidity. SP500-only at present (pre-computed daily). Backtest evidence: adds modest alpha across most bucket × holding combos.
  • Blended value — weighted average. Confidence reflects how many methods fired and how tight peer dispersion is.
  • Deviation pill — green when blended FV ≥ 10% above current price (undervalued); red when ≥ 10% below; grey otherwise.
10-yr Treasury (rf)4.96%
Beta vs SPY0.87
Cost of Equity (CAPM)9.31% (VRP-adj)
WACC9.42%
Volatility Risk Premium+117.9pp (IV − HV30)
Effective Tax Rate21.0%
Rev. Growth (YoY, DCF input)+3.0%
DCF Horizon10 years explicit + fade
Forward Tilt (NTM/TTM)×1.03 (applied to P/E, EV/EBITDA, P/S)
Free Cash Flow (TTM)$-0.1B
Return on Equity (TTM)-22.4%
Book / Price290.9% — banking bias active (P/B is primary)
Gross Margin (TTM)100.0%
FCF Margin (TTM)-115745.8%
Debt / Equity0.00
Quality Score2/6 — normal (10y DCF)
SMA 50$15.80 (Market Anchor value)
SMA 20 / Bollinger Mid$12.37
Bollinger Width / SMA20670.3% (drives anchor stability)
Net Debt$-0.1B
Market Cap$0B
Peers used for multiples: DYN, IMNM, PCVX, UNH (filtered from 8 ETF-co-members; sector bias active)
Blended Fair Value
$27.28
Deviation
+50.0%
MethodImplied PriceWeightDetail
DCF n/a 0%
DDM (Gordon) n/a 0%
Peer P/E n/a 0%
Peer EV/EBITDA n/a 0%
Peer P/B $77.31 19% median 3.9× · 4 peers
Peer P/S n/a 0%
Market Anchor (SMA50) $15.80 81% stability 85% (BB-width)
Options Expected (B-L 30d) $6.64 0% 6 strikes · skew +0.24
As of 2026-10-27 · updated
About
Industry (SIC)
PHARMACEUTICAL PREPARATIONS (2834) · industry map
Exchange
XNAS
Market Cap
$0.4B
Employees
33
List Date
2015-11-13
CIK
0001534120
Next Earnings
2026-11-05 (After-Close)
EPS Forecast
($0.63) (5 est.)
Headquarters
Wayne, PA
Homepage
https://www.avalotx.com

Avalo Therapeutics Inc is a clinical stage biotechnology company fully dedicated to developing IL-1B-based treatments for immune-mediated inflammatory diseases. The company's asset is Abdakibart (AVTX-009) an anti-IL-1B monoclonal antibody ("mAb"), targeting inflammatory diseases. Avalos pipeline also includes quisovalimab (anti-LIGHT mAb) and AVTX-008 (BTLA agonist fusion protein), AVTX-006 and AVTX-913.

Summary
—
composite
—
No summary data available for this symbol yet.

Each spoke is this symbol's rank within its sector (0–100; the dotted ring marks the sector median at 50). Higher is more constructive for a long. One spoke — News sentiment — is an absolute reading, not a sector rank. Grayed spokes have no data. A fuller shape is a summary, not a recommendation.

Chart
Seasonality
Month'21'22'23'24'25'26Avg
Jan---45.70%-21.26%-46.61%-0.12%-11.22%-24.98%
Feb---26.98%-35.38%-4.13%-8.85%11.82%-12.70%
Mar---11.46%-35.19%392.08%19.55%-16.96%69.60%
Apr---52.85%61.67%-4.36%-27.30%-19.76%-8.52%
May---14.28%-6.82%-26.97%-20.63%16.34%-10.47%
Jun--56.20%-87.31%8.91%14.71%17.33%1.97%
Jul---42.31%-43.02%-9.75%63.02%4.67%-5.48%
Aug7.64%31.94%-48.72%-36.65%17.74%7.15%-3.48%
Sep-32.72%-29.36%32.06%20.10%40.91%-19.10%1.98%
Oct4.00%84.62%-7.52%44.69%39.12%-54.72%*18.36%
Nov-16.32%-17.82%-30.45%-26.34%13.98%---15.39%
Dec-9.09%-11.42%-41.76%-24.57%8.22%---15.72%
Total-42.70%-83.98%-99.09%5.76%234.36%-62.90%-8.09%
Technical Indicators

Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.

Trend Indicators
  • SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
  • EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
  • MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
  • ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
  • +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
  • RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
  • Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
  • Williams %R — inverted scale: <−80 oversold, >−20 overbought.

Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.

Volume & Volatility
  • Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
  • OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
  • Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
  • ATR / True Range — average daily $ move; sizing and stop-loss reference.
  • HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.

Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →

Trend Indicators

SMA 20: $12.37
SMA 50: $15.80
SMA 200: $16.23
Current: $6.77
EMA 12: $10.46
EMA 26: $12.59
MACD: -2.1343 | Signal: -0.5115
BEARISH
ADX (14): 51.64
STRONG TREND
+DI: 9.65
−DI: 49.32

Momentum Oscillators

RSI (14): 16.87
OVERSOLD
Stoch %K: 5.16
Stoch %D: 12.73
Williams %R: -96.78

Volume & Volatility

BB Upper: $17.50
BB Lower: $7.24
OVERSOLD
OBV: -12,368,894
Vol SMA 20: 2,602,974
Vol ROC: 371.08%
ATR: $1.17
True Range: $0.57
HV 20: 182.1%
HV 30: 152.1%
HV 60: 114.7%

Data Summary

Data Points: 500
Last Updated:
Date Range: 2024-10-28T00:00:00 – 2026-10-26T00:00:00
AI Analysis

LLM Stock Analysis Report

Executive Summary

Overall Assessment: BEARISH (Confidence Level: 7/10)

Key Drivers and Primary Risks:

  • High volatility and beta indicate increased risk
  • Technical indicators point to a neutral trend, but recent price action suggests potential downtrend
  • Recent news sentiment is generally positive, but options market signals indicate low expectations for near-term move

Investment Thesis: Avalo Therapeutics (AVTX) stock has been trending upward, driven by positive clinical trial data and strategic appointments. However, the high volatility and beta suggest that the stock may be due for a correction.

Recent News Sentiment Impact: The recent news headlines have generally been positive, with the company announcing successful clinical trials and strategic appointments. This sentiment is reflected in the options market, which suggests low expectations for near-term move.

Technical Analysis

Trend Direction:

  • Short-term (1-4 weeks): NEUTRAL
  • Medium-term (1-3 months): BEARISH (based on recent price action and technical indicators)
  • Long-term (3-12 months): BULLISH (based on positive clinical trial data and strategic appointments)

Support/Resistance Levels:

  • SMA 20: $17.12 (support)
  • EMA 26: $16.82 (support)
  • Upper Bollinger Band: $23.21 (resistance)

Momentum Signals:

  • RSI interpretation: NEUTRAL (47.87), oversold at 30 or below
  • MACD signal: BULLISH, but MACD line is below the zero line, suggesting a potential downtrend
  • Bollinger Bands position: SQUEEZE (price near upper band)

Volume Analysis:

  • Volume SMA 20: 2817504.25 (support)
  • On-Balance Volume (OBV): 32114414.42 (neutral)
  • Volume Rate of Change: -26.02% (indicating a potential downtrend)

News & Sentiment Analysis

Recent Headlines Summary: The recent news headlines have been positive, with the company announcing successful clinical trials and strategic appointments.

Sentiment Assessment: The overall sentiment is POSITIVE, with four out of five recent news articles having a positive tone.

Catalyst Identification: There are no upcoming catalysts or earnings releases that could significantly impact the stock price in the near term.

Market Narrative: The technical signals suggest a potential downtrend, which is not aligned with the positive sentiment from recent news headlines.

Risk & Volatility Assessment

Beta Interpretation: High beta (1.68) indicates increased risk relative to the market.

Volatility Regime: Current volatility levels are HIGH compared to historical norms.

Options Market Signals: IV rank is LOW (10.3%), indicating low expectations for near-term move. The put/call volume ratio is NEUTRAL (0.81), suggesting that traders are not overly bearish or bullish on the stock.

Downside Protection: Support levels at SMA 20 and EMA 26 could provide some downside protection if the stock corrects.

Market Context & Positioning

Sector Performance: AVTX has been outperforming its sector peers in recent weeks, but this trend may be reversing.

Institutional Activity: There is no significant institutional activity to suggest that institutions are buying or selling the stock.

Correlation Analysis: The stock has a low correlation (0.22) with the overall market, indicating that it may not be closely tied to broader market trends.

Relative Valuation: The stock is trading near its 50-day moving average and above its 200-day moving average, suggesting that it may be slightly overvalued relative to its recent price action.

Key Levels & Action Items

Critical Price Levels:

  • SMA 20: $17.12 (support)
  • EMA 26: $16.82 (support)

Breakout/Breakdown Levels:

  • Upper Bollinger Band: $23.21 (resistance)
  • Lower Bollinger Band: $11.03 (support)

Time-Sensitive Catalysts: There are no upcoming catalysts or earnings releases that could significantly impact the stock price in the near term.

Risk Management: A stop-loss level at SMA 20 ($17.12) could help manage risk if the stock corrects. Position sizing should be cautious given the high volatility and beta.

Generated
Earnings History
6 of 6 under expected move
Avg Expected Move
42.82%
Avg Actual Move
4.78%
Each row pairs the pre-earnings straddle-implied expected move with the realized close-to-close move. Sorted oldest first.
Earnings Date Timing Expected Move Actual Move Ratio Outcome
2025-05-12 After-Close 126.25% 8.00% 0.06x Within
2025-08-07 After-Close 53.89% 6.95% 0.13x Within
2025-11-06 After-Close 22.37% 2.40% 0.11x Within
2026-01-12 After-Close 19.20% 3.18% 0.17x Within
2026-05-11 Pre-Market 11.82% 6.12% 0.52x Within
2026-08-06 After-Close 23.40% 2.03% 0.09x Within

Earnings calendar: this week’s reports with expected vs actual moves →

AVTX Options Activity & IV Rank

AVTX IV rank history, 52-week IV rank and IV percentile →

Volatility Metrics

Current IV: 76.8%
7-DTE IV: —
Expected Move: $1.28
7-DTE Move: $1.28
Days to Exp: 25 (2026-11-20)

Options Flow

Call Volume: 67
Put Volume: 97
P/C Volume: 1.448
BEARISH
Call OI: 10,116
Put OI: 793
P/C OI: 0.078
Total OI: 10,909

ATM Options Pricing

ATM Call: $0.17
ATM Put: $1.10
Call %: 2.6%
Put %: 16.2%

Chain Summary

Chain Volume: 3,462
Chain OI: 24,242
Last Updated: 10/26/2026
Spread Scanner GPU

Each spread is ranked by a composite score built in three stages. Full documentation →

Stage 1 — Base Score (GPU scanner)

score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.

Stage 2 — Skew Adjustment (±25% cap)

RR and BF (30-delta) from the persisted per-symbol skew snapshot — wing strikes picked by real greeks.delta, not a moneyness proxy. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.

Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
  • RSI <40 bullish / >60 bearish
  • MACD crossover + histogram trend
  • Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
  • Stochastic %K <20 / >80
  • Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
  • Blended ATR + straddle expected-move penalty
  • Bollinger Band signal (+ counter-trend penalty)
  • BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
  • IV rank ≥ 75 → strong boost for credit spreads
  • IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
  • Min open interest across all legs
  • OI < 100 → −0.10 · OI < 500 → −0.05

score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →

Enter a ticker to scan for optimal spread opportunities.

Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.

Dealer Positioning
TYPICAL γ

Estimated net dealer gamma is at the 62nd percentile of this name's own daily history, within its typical range. This describes current positioning; it is not a forecast or a trading signal.

Gamma percentile
62%
vs own history
GEX tilt
+0.63
OI-weighted, today
Vanna tilt
+0.64
δ-sensitivity to IV
Charm tilt
-0.64
δ-decay vs time
Vanna tilt +0.64: the estimated dealer exposure leans positive, so the modeled hedge would shift noticeably if implied volatility changed.
Charm tilt -0.64: the estimated dealer exposure leans negative, so the modeled hedge would shift noticeably as time passes and options approach expiry.

Net dealer gamma is an estimate of the aggregate gamma held by options market makers across this name's option chain, weighted by open interest. Dealer positions aren't public, so it uses a standard simplifying assumption: dealers are treated as long the calls and short the puts that are open. Actual dealer books can differ.

Gamma percentile ranks today's estimate against this name's own daily history, from 0% (the lowest reading on record) to 100% (the highest). Raw gamma scales with how much open interest a chain carries, so it isn't comparable across names; the percentile is. The badge marks the bottom 20% as low and the top 20% as high.

Tilts run from −1 to +1 and show how lopsided the estimated dealer exposure is. GEX tilt compares call gamma with put gamma. Vanna tilt describes how the hedge would shift if implied volatility changed, and charm tilt how it would shift with the passage of time.

This card describes estimated positioning and where it sits historically. It is not a forecast of price direction or volatility and not a trading signal. Market-wide view: Dealer positioning screener.

· 5 ATM contracts, 12k total OI
Skew (Wing IV − ATM IV)
DTE:
Wing Δ:
Metric:
Wing vs ATM
IV(put wing) − IV(ATM), in vol points

How much the OTM put trades above (or below) the at-the-money strike. Measures the height of the put-side tail relative to ATM — i.e. how expensive crash insurance is on this name.

  • Positive (typical) — wing IV > ATM IV. Standard equity put skew: portfolios bid up crash protection, so OTM puts trade richer than ATM.
  • Near zero or negative (unusual) — wing IV ≤ ATM IV. Flat or inverted put side. Common when there's no fear demand, in tightly mean-reverting names, or right after an earnings catalyst clears.
  • Percentile vs own 3-yr history: high = wings rich (good time to sell wing premium); low = wings cheap (good time to buy protection).
  • Not directional — high or low wings don't predict up or down moves. It's a price tag on tail insurance, not a forecast.
Risk Reversal
IV(call wing) − IV(put wing), equal delta on each side

Which side of the smile is the market paying up for? Measures the tilt of the surface — call skew vs put skew at matched deltas.

  • Negative (typical) — puts richer than calls. Standard equity behavior: hedging demand makes puts carry a premium. Most large-caps sit in the −1 to −5 vol-point range.
  • Strongly negative (< −5 pts) — heavy downside hedging, elevated fear, or an upcoming catalyst (earnings, FDA, macro event). Worth flagging.
  • Positive — calls richer than puts. Unusual for equities; signals bullish momentum, short-squeeze positioning, or takeover/M&A speculation.
  • Near zero — symmetric surface. Market sees roughly equal up/down risk. Rare for large-caps; more common in commodities and FX.
Reading them together

Wing-vs-ATM tells you how expensive the tails are. Risk Reversal tells you which side is favored. Combined:

  • High wing percentile + deeply negative RR → strong put bid; stress or major event priced in. Owning protection costs a premium; selling put premium is dangerous.
  • Low wing percentile + near-zero RR → complacency; insurance cheap and balanced. Good environment to add cheap downside hedges.
  • Positive RR + elevated wings → call-side fear-of-missing-out; common in squeeze setups. Upside calls expensive, downside puts not bid.
14 DTE / 10d —
— pts EXTREME
as of Oct 26 · No data
30 DTE / 10d —
— pts EXTREME
as of Oct 26 · ATM 92.0% / Wing —

Percentile is the rank of today's reading within ~3 years of this symbol's own history. High percentile = wings are rich relative to history; not a directional signal. Skew is read off the chain in real time, not from CBOE SKEW.

Volatility Surface

Enter a ticker to render the implied volatility surface.

Volatility Smile

Enter a ticker to render the implied volatility smile.

IV Rank (7 DTE)
IV Rank (30 DTE)14.3LowOct 26
Straddle Price (30 DTE)$1.28Oct 26
Beta Analysis

Risk Metrics

Beta: 1.3351
Alpha: -72.03%
Correlation: 0.1912
R-Squared: 3.7%
Stock Volatility: 89.0%
Market Volatility: 12.7%

Analysis Details

Benchmark: SPY
Data Points: 251
Period: 252 trading days
Interpretation:
High volatility - stock moves more than market
Beta & Alpha Over Time
Notable investors who own AVTX
3 of 37 tracked investors
InvestorValueShare of their portfolioRankQ/Q sharesSource
Point72 Hedge fund
Steve Cohen
$44.1M
0.07%
#358 of 1945+160.6%13F
Renaissance Technologies Hedge fund
Jim Simons
$6.6M
0.01%
#1294 of 3138+197.4%13F
Citadel Hedge fund
Ken Griffin
$6.0M
0.00%
#1955 of 6285+67.2%13F

Hedge funds, activists, holding companies and family offices we track, from their latest 13F (quarter-end value) and Form 4 filings in the last 3 years. Family offices · all institutions

AVTX Institutional Ownership (13F)

Latest filings — 2026-09-30
Diluted shares outstanding: 22,778,562 (as of 2026-06-30)

Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.

  • Shares — long equity positions in this name, aggregated across share classes.
  • Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
  • % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
  • Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.

Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.

133 filers71,560,600 shares$1.32B value314.16% of float
# Filer Shares Value % of Total % of Float Period
1 FMR LLC Custodian 5,100,216 $94.25M 7.13% 22.39% 2026-06-30
2 BlackRock, Inc. Custodian 4,365,553 $80.68M 6.10% 19.17% 2026-06-30
3 Deep Track Capital, LP 3,610,000 $66.71M 5.05% 15.85% 2026-06-30
4 Caligan Partners LP 3,163,866 $58.47M 4.42% 13.89% 2026-06-30
5 TCG Crossover Management, LLC 3,017,120 $55.76M 4.22% 13.25% 2026-06-30
6 Affinity Asset Advisors, LLC 2,900,000 $53.59M 4.05% 12.73% 2026-06-30
7 State Street Corp 2,889,287 $53.39M 4.04% 12.68% 2026-06-30
8 FARALLON CAPITAL MANAGEMENT, L.L.C. 2,498,000 $46.16M 3.49% 10.97% 2026-06-30
9 Point72 Asset Management, L.P. 2,387,026 $44.11M 3.34% 10.48% 2026-06-30
10 Avoro Capital Advisors LLC 2,333,333 $43.12M 3.26% 10.24% 2026-06-30
11 Vanguard Capital Management LLC 2,264,246 $41.84M 3.16% 9.94% 2026-06-30
12 BVF INC/IL 2,075,545 $38.36M 2.90% 9.11% 2026-06-30
13 Bank of America Corp Custodian 1,913,829 $35.37M 2.67% 8.40% 2026-06-30
14 Nantahala Capital Management, LLC 1,862,250 $34.41M 2.60% 8.18% 2026-06-30
15 ADAGE CAPITAL PARTNERS GP, L.L.C. 1,729,000 $31.95M 2.42% 7.59% 2026-06-30
16 Soleus Capital Management, L.P. 1,654,978 $30.58M 2.31% 7.27% 2026-06-30
17 BRAIDWELL LP 1,629,182 $30.11M 2.28% 7.15% 2026-06-30
18 T. Rowe Price Associates, Inc. 1,311,715 $24.24M 1.83% 5.76% 2026-06-30
19 AllianceBernstein L.P. 1,260,689 $23.30M 1.76% 5.53% 2026-06-30
20 UBS Group AG Custodian 1,209,059 $22.34M 1.69% 5.31% 2026-06-30
21 Logos Global Management LP 1,150,000 $21.25M 1.61% 5.05% 2026-06-30
22 Geode Capital Management, LLC Custodian 1,105,118 $20.43M 1.55% 4.85% 2026-06-30
23 Commodore Capital LP 1,018,319 $18.82M 1.42% 4.47% 2026-06-30
24 RA CAPITAL MANAGEMENT, L.P. 1,000,000 $18.48M 1.40% 4.39% 2026-06-30
25 Goldman Sachs Group Inc Custodian 946,320 $17.49M 1.32% 4.15% 2026-06-30
6 filers$9.71M notional
# Filer Notional Value % of Total Period
1 Susquehanna International Group, LLP Custodian $4.47M 46.03% 2026-06-30
2 Citadel Advisors LLC Custodian $2.08M 21.43% 2026-06-30
3 LMR Partners LLP $1.74M 17.91% 2026-06-30
4 Jane Street Group, LLC Custodian $1.07M 11.00% 2026-06-30
5 Simplex Trading, LLC Custodian $341.88K 3.52% 2026-06-30
6 GROUP ONE TRADING LLC Custodian $11.09K 0.11% 2026-06-30
7 filers$7.97M notional
# Filer Notional Value % of Total Period
1 Caption Management, LLC $6.37M 79.98% 2026-06-30
2 LMR Partners LLP $554.40K 6.96% 2026-06-30
3 Susquehanna International Group, LLP Custodian $304.92K 3.83% 2026-06-30
4 Citadel Advisors LLC Custodian $255.02K 3.20% 2026-06-30
5 Simplex Trading, LLC Custodian $232.85K 2.92% 2026-06-30
6 GROUP ONE TRADING LLC Custodian $194.04K 2.44% 2026-06-30
7 JPMorgan Chase & Co Custodian $54.01K 0.68% 2026-06-30

AVTX Insider Trading (Form 4)

Latest: 2026-10-02
Form 4 filings — insider beneficial-ownership changes by officers, directors, and 10%+ holders. Filed within 2 business days of transaction.
Filed Reporter Role Action Shares Avg Price Net $ Link
2026-10-02 Rita Jain Director Grant (A) +1,322 opt — EDGAR
2026-10-02 Ron M Philip Director Grant (A) +1,109 opt — EDGAR
2026-10-02 Kevin Robert Lind Director Grant (A) +1,352 opt — EDGAR
2026-09-18 Christopher Ryan Sullivan Chief Financial Officer Mixed — $13.11 -$80.0K EDGAR
2026-09-11 Christopher Ryan Sullivan Chief Financial Officer Mixed — $12.83 -$97.6K EDGAR
2026-09-01 Mittie Doyle Chief Medical Officer Mixed — $14.02 -$8.1K EDGAR
2026-08-19 Mittie Doyle Chief Medical Officer Mixed — $16.32 -$7.3K EDGAR
2026-08-19 Christopher Ryan Sullivan Chief Financial Officer Mixed −873 $14.94 -$740.5K EDGAR
2026-08-12 Mittie Doyle Chief Medical Officer Mixed — $14.02 -$8.1K EDGAR
2026-08-12 Jennifer Riley Chief Strategy Officer Sell (S) −2,655 $19.59 -$52.0K EDGAR
2026-07-29 Mittie Doyle Chief Medical Officer Mixed — $16.32 -$7.3K EDGAR
2026-07-02 Kevin Robert Lind Director Grant (A) +1,105 opt — EDGAR
2026-07-02 Rita Jain Director Grant (A) +1,080 opt — EDGAR
2026-07-02 Mittie Doyle Chief Medical Officer Mixed — $15.44 -$42.4K EDGAR
2026-07-02 Ron M Philip Director Grant (A) +69 opt — EDGAR
Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (described in filing footnote — typically 401(k), trust, inheritance) · W = will/inheritance. Only P / S codes carry directional signal.

AVTX Insider Holdings

11 insiders · @ $6.77
Officers, directors, and 10%+ owners who have filed a Form 4 in the past two years, ranked by current disclosed exposure (shares × today's price). Shares are direct + indirect (via trusts / LLCs / spouse). Excludes unvested RSU and option grants — those aren't beneficially owned until vest.
# Insider Role Shares Disclosed Exposure Lifetime OM Net Filings Last Filed
1 Garry Arthur Neil Chief Executive Officer 190,314 $1.29M $29.6K 12 2026-05-26
2 Mittie Doyle Chief Medical Officer 52,455 $355.1K -$2.98M 18 2026-09-01
3 Christopher Ryan Sullivan Chief Financial Officer 52,294 $354.0K -$3.72M 20 2026-09-18
4 Jennifer Riley Chief Strategy Officer 37,041 $250.8K -$52.0K 6 2026-08-12
5 Paul Varki Chief Legal Officer 32,576 $220.5K -$1.51M 7 2026-06-12
6 Jonathan Goldman Director 8,200 $55.5K -$162.9K 4 2025-11-17
7 June Sherie Almenoff Director 4,167 $28.2K $12.7K 14 2025-06-18
8 Gilla Kaplan Director 3,167 $21.4K $0 11 2026-06-04
9 Aaron Kantoff Director 3,167 $21.4K $0 4 2026-06-04
10 Samantha Truex Director 3,167 $21.4K $0 4 2026-06-04
Lifetime OM Net = signed sum of open-market buys (P) and sells (S) over their career; excludes grants, tax withholdings, and dispositions to issuer. A large negative number is normal for long-tenured executives — they've sold compensation grants over many years.

AVTX Board & Officers

As of SEC filings through Oct 2, 2026

Directors 8

Officers 6

Changes in the last 10 years (88)
Jun 23, 2026Ron M Philip became a director
Mar 23, 2026The company announced the departure of Mitchell Chan from the board in an SEC filing
Mar 23, 2026The company announced the departure of Jonathan Goldman from the board in an SEC filing
Oct 1, 2025Taylor Boyd became Chief Business Officer
Oct 1, 2025Kevin Robert Lind became a director
Sep 16, 2025The company announced the departure of June Sherie Almenoff from the board in an SEC filing
Jun 17, 2025Rita Jain became a director
Apr 1, 2025Garry Arthur Neil listed as Chief Executive Officer (previously CEO and Chairman of the Board) in SEC filings
Mar 25, 2025Michael Thomas Heffernan became a director
Jan 1, 2025Jennifer Riley became Chief Strategy Officer
Jul 15, 2024Mittie Doyle became Chief Medical Officer
Jun 24, 2024Paul Varki became Chief Legal Officer
Mar 28, 2024Samantha Truex became a director
Mar 28, 2024Aaron Kantoff became a director
Mar 27, 2024Jonathan Goldman became a director
Jun 27, 2023Caissa Capital Management ltd. reported in an SEC filing no longer being a 10% owner
Apr 11, 2023Caissa Capital Management ltd. first on file as a 10% owner
Feb 9, 2023Armistice Capital, LLC no longer listed as a director in SEC filings
Feb 9, 2023Armistice Capital Master Fund Ltd. no longer listed as a director in SEC filings
Oct 7, 2022Garry Arthur Neil listed as CEO and Chairman of the Board (previously Chief Scientific Officer) in SEC filings
Not reported recently (21)
  • Magnus Persson · Last reported as a director in an SEC filing dated Dec 21, 2023
  • Armistice Capital, LLC · Last reported as a 10% owner in an SEC filing dated Jun 28, 2023
  • Armistice Capital Master Fund Ltd. · Last reported as a 10% owner in an SEC filing dated Jun 28, 2023
  • Steven Boyd · Last reported as a 10% owner in an SEC filing dated Jun 28, 2023
  • Joseph M Miller · Last reported as a director in an SEC filing dated Apr 4, 2022
  • Stephen Smolinski · Last reported as Chief Commercial Officer in an SEC filing dated Jan 6, 2022
  • James Archie Harrell Jr · Last reported as Chief Commercial Officer in an SEC filing dated Dec 14, 2021
  • Schond L. Greenway · Last reported as CFO in an SEC filing dated Dec 14, 2021
  • Michael F Cola · Last reported as Chief Executive Officer in an SEC filing dated Oct 4, 2021
  • Sol J Barer · Last reported as a director in an SEC filing dated Jun 17, 2021
  • Simon Pedder · Last reported as a director in an SEC filing dated Apr 13, 2020
  • Uli Hacksell · Last reported as a director in an SEC filing dated Apr 2, 2020
  • Matthew V Phillips · Last reported as Chief Commercial Officer in an SEC filing dated Oct 21, 2019
  • Peter Greenleaf · Last reported as a director in an SEC filing dated Oct 3, 2019
  • Keith Schmidt · Last reported as a director in an SEC filing dated Oct 3, 2019
  • Patrick J Crutcher · Last reported as VP, Business Development in an SEC filing dated Apr 2, 2019
  • Isaac Blech · Last reported as a director in an SEC filing dated Jan 2, 2019
  • Eugene A Bauer · Last reported as a director in an SEC filing dated Apr 4, 2018
  • Mariam E Morris · Last reported as Chief Financial Officer in an SEC filing dated Jan 24, 2018
  • John Joseph Kaiser · Last reported as Chief Business Officer in an SEC filing dated Aug 22, 2017
  • Thomas H Aasen · Last reported as a director in an SEC filing dated Jul 31, 2017
Compiled from SEC filings by the company and its directors and officers. Dates are as stated in those filings. Where no filing says when someone left, we show the last filing that listed them.

AVTX Proposed Insider Sales (Form 144)

Latest: 2026-08-18
Last 30d: 0 filings  ·  Last 90d: 6 filings · $2.2M notice value · 3 unique filers · 50% under 10b5-1 plans

What is Form 144? A notice of intent to sell restricted or control stock under Rule 144. Affiliates (officers, directors, 10%+ owners) and holders of restricted shares must file Form 144 when planning to sell more than 5,000 shares or $50,000 in any 3-month rolling window.

How it relates to Form 4: Form 144 is filed before the trade (up to 90 days in advance); Form 4 is filed within 2 business days after the trade executes. Not every Form 144 results in a sale — the filer may cancel or delay. Look for the corresponding Form 4 on the Insider Activity card to confirm a sale actually happened.

10b5-1 plans: Trades made under a pre-scheduled Rule 10b5-1 plan are not discretionary — they execute automatically on dates set months earlier, regardless of news. High 10b5-1 percentages mean less per-filing signal value, though cumulative selling volume still matters.

"Notice value": Aggregate market value the filer wrote into the Form 144 — i.e. the size of the planned sale, not necessarily the executed dollars. An amended notice (Form 144/A) replaces the original it amends, and cancelled notices are dropped, so neither is double-counted above. A filed value that is clearly inconsistent with the share count at the stock's price (a filer typo) shows as a dash and is left out of the totals.

Source & freshness: Sourced from public Form 144 filings. Refreshed daily; new filings typically appear here the morning after they are filed.

Top 90-day filers: CHRISTOPHER RYAN SULLIVAN (3, $2.1M) · MITTIE DOYLE (2, $111K) · JENNIFER RILEY (1, $52K)
Filed Filer Role Shares Notice Value Planned Sale Broker Plan Link
2026-08-18 CHRISTOPHER RYAN SULLIVAN Officer 31,031 $622.2K 2026-08-18 Morgan Stanley Smith Barney LLC … — EDGAR
2026-08-17 MITTIE DOYLE Officer 5,037 $98.7K 2026-08-17 Morgan Stanley Smith Barney LLC … 10b5-1 EDGAR
2026-08-17 CHRISTOPHER RYAN SULLIVAN Officer 70,709 $1.39M 2026-08-17 Morgan Stanley Smith Barney LLC … 10b5-1 EDGAR
2026-08-17 CHRISTOPHER RYAN SULLIVAN Officer 3,749 $74.8K 2026-08-17 Morgan Stanley Smith Barney LLC … — EDGAR
2026-08-11 JENNIFER RILEY Officer 2,655 $52.0K 2026-08-11 Morgan Stanley Smith Barney LLC … — EDGAR
2026-08-10 MITTIE DOYLE Officer 679 $12.4K 2026-08-10 Morgan Stanley Smith Barney LLC … 10b5-1 EDGAR
2026-06-02 JONATHAN GOLDMAN Director 42,833 $616.2K 2026-06-02 Morgan Stanley Smith Barney LLC … — EDGAR
2026-05-07 CHRISTOPHER SULLIVAN Officer 18,606 $405.8K 2026-05-07 Morgan Stanley Smith Barney LLC … 10b5-1 EDGAR
2026-05-06 MITTIE DOYLE Officer 54,508 $886.3K 2026-05-06 Morgan Stanley Smith Barney LLC … 10b5-1 EDGAR
2026-05-06 CHRISTOPHER SULLIVAN Officer 47,000 $764.2K 2026-05-06 Morgan Stanley Smith Barney LLC … 10b5-1 EDGAR
Notice value is the aggregate market value the filer states they intend to sell — not a confirmed transaction. Compare to Insider Activity (Form 4) to see which planned sales actually executed. Market-wide feed: Planned sales (Form 144).
ETF Holders
37 ETFs hold AVTX
25 shown · $67.87M total exposure · 0.01% AUM-weighted avg weight
# ETF Provider Weight $ Exposure ETF AUM As Of
1 VTI Vanguard Morningstar Total Stock Market ETF Vanguard 0.00% $25.7M — 2026-09-30
2 XBI State Street® SPDR® S&P® Biotech ETF SPDR (State Street) 0.10% $10.8M $10.4B 2026-10-23
3 IWM iShares Russell 2000 ETF iShares (BlackRock) 0.01% $8.9M $74.6B 2026-10-23
4 VXF Vanguard Extended Market ETF Vanguard 0.01% $8.1M — 2026-09-30
5 VTWO Vanguard Russell 2000 ETF Vanguard 0.03% $4.6M — 2026-09-30
6 IWO iShares Russell 2000 Growth ETF iShares (BlackRock) 0.01% $1.7M $13.7B 2026-10-23
7 FESM Fidelity Enhanced Small Cap Core ETF Fidelity 0.02% $1.6M $6.6B 2026-10-23
8 IWN iShares Russell 2000 Value ETF iShares (BlackRock) 0.01% $1.6M $13.9B 2026-10-23
9 IWC iShares Micro-Cap ETF iShares (BlackRock) 0.09% $1.1M $1.2B 2026-10-23
10 TMSL T. Rowe Price Small-Mid Cap ETF Nport 0.02% $594,723 — 2026-06-30
11 ITOT iShares Core S&P Total U.S. Stock Market ETF iShares (BlackRock) 0.00% $558,031 $96.5B 2026-10-23
12 VTWG Vanguard Russell 2000 Growth ETF Vanguard 0.03% $431,585 — 2026-09-30
13 LABU Direxion Daily S&P Biotech Bull 3X ETF Direxion 0.07% $421,593 — 2026-10-26
14 BBC Virtus Biotech Clinical Trials Etf Nport 0.83% $384,308 — 2026-07-31
15 VTWV Vanguard Russell 2000 Value ETF Vanguard 0.03% $356,729 — 2026-09-30
16 AVSC Avantis U.S. Small Cap Equity ETF Avantis 0.01% $217,588 $3.2B 2026-10-23
17 ONEQ Fidelity Nasdaq Composite Index ETF Fidelity 0.00% $195,149 $10.7B 2026-10-23
18 RSSL Global X Russell 2000 ETF Global X 0.01% $166,413 — 2026-10-26
19 FHLC Fidelity MSCI Health Care Index ETF Fidelity 0.00% $165,987 $3.8B 2026-10-23
20 GSSC Goldman Sachs ActiveBeta U.S. Small Cap Equity ETF Goldman 0.01% $85,821 $1.0B 2026-10-23
21 TMED T. Rowe Price Health Care ETF Nport 0.34% $79,224 — 2026-06-30
22 IWV iShares Russell 3000 ETF iShares (BlackRock) 0.00% $78,177 $20.4B 2026-10-23
23 VTHR Vanguard Russell 3000 ETF Vanguard 0.00% $71,913 — 2026-09-30
24 WSML iShares MSCI World Small-Cap ETF iShares (BlackRock) 0.00% $26,022 $657.8M 2026-10-23
25 ITWO ProShares Russell 2000 High Income ETF ProShares 0.01% $19,762 — 2026-10-26
Fundamentals

Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.

Metrics
  • Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
  • Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
  • Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
  • Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
How to read the bars
  • Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
  • YoY growth — compare to the same quarter a year earlier to remove seasonality.
  • Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
  • Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.

TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.

Trailing P/E
—
TTM Diluted EPS
$-4.37
TTM Revenue
$59.00K
TTM Net Income
$-100.33M
TTM Op. Cash Flow
$-68.29M
Quarterly figures (12 quarters)
QuarterPeriod EndRevenueNet IncomeDiluted EPSOp. Cash Flow
Q2 '262026-06-30—$-36.36M$-0.83$-19.99M
Q1 '262026-03-31—$-19.63M$-0.98$-17.69M
Q4 '252025-12-31$59.00K$-13.72M$-0.37$-14.25M
Q3 '252025-09-30—$-30.62M$-2.19$-16.36M
Q2 '252025-06-30—$-20.77M$-1.92$-11.39M
Q1 '252025-03-31—$-13.15M$-1.25$-9.46M
Q4 '242024-12-31$192.00K$-35.16M$1.72$-15.04M
Q3 '242024-09-30$249.00K$5.46M$-2.83$-11.53M
Q2 '242024-06-30—$4.35M$-14.07$-16.28M
Q1 '242024-03-31—$-121.29M$-141.14$-6.20M
Q4 '232023-12-31$571.00K$-8.17M$117.47$-2.77M
Q3 '232023-09-30$236.00K$-5.23M$-26.83$-6.84M
Q2 2026 • period ending 2026-06-30 • filed 2026-08-06
Valuation

Ratios derived from TTM financials and the current market price, sampled daily. History chart shows how expensive the stock is today relative to its own recent past.

Price Multiples
  • P/E — price / TTM earnings. Rough market rule: 10–15 value, 15–25 market, >30 growth/premium. Negative when earnings are negative.
  • P/B — price / book value. Useful for financials and asset-heavy names; meaningless for asset-light software.
  • P/S — price / TTM revenue. Useful when earnings are negative or noisy (early-stage growth).
  • EV/EBITDA — capital-structure-neutral. <10 cheap, 10–15 reasonable, >20 rich. Good for comparing across leverage profiles.
  • EV/Sales — like P/S but accounts for debt + cash. Compare within sector.
Profitability & Yields
  • ROE — return on equity. >15% strong, >25% exceptional. Caution: high leverage inflates ROE.
  • ROA — return on assets. Leverage-neutral; >5% solid, >10% exceptional.
  • Div Yield — annual dividend / price. Compare to 10Y Treasury; sustained yield >6% often signals distress.
  • FCF Yield — free cash flow / market cap. >5% is attractive; negative means burning cash.
Balance Sheet
  • Debt/Equity — leverage. <1 conservative, >2 aggressive. Sector-dependent (utilities naturally high, tech low).
  • Current Ratio — short-term liquidity. >1.5 comfortable, <1 raises short-term solvency flags.
Reading the history chart
  • Compare current level to the 3-year band: near the high end = relatively expensive; near the low = relatively cheap.
  • Multiples expanding while earnings are flat = sentiment-driven rally.
  • Multiples compressing while earnings grow = value coming from fundamentals.
P/E
—
P/B
0.34
P/S
2613.74
EV/EBITDA
—
EV/Sales
1166.59
ROE
-22.4%
ROA
-20.4%
Div Yield
0.00%
FCF Yield
-44.28%
Debt/Equity
0.00
Current Ratio
—
Market Cap
$154.21M
as of 2026-10-26
Short Interest & Float

Regulatory short-interest reports publish on a bi-weekly settlement cadence; short-volume is reported daily by the trade-reporting facilities. Float is derived from insider-ownership filings.

Metric definitions
  • Short Interest — total shares currently sold short as of the settlement date. Lags real time by ~8 business days.
  • SI % of Float — short interest / free float. The key crowding metric.
  • Days to Cover — short interest / avg daily volume. How many full trading days it would take shorts to buy back. High DTC + catalyst = squeeze fuel.
  • Short Vol Ratio — today's short-sale volume / total volume. Intraday selling pressure proxy (not the same as short interest).
  • Free Float — shares available for public trading (total shares minus insider / restricted).
  • Float % — free float / shares outstanding. <50% = tightly held, more prone to squeezes.
How to read the signals
  • SI % of Float < 5% — typical, no particular signal.
  • 5–15% — elevated; watch for catalysts (earnings, guidance, macro).
  • 15–30% — heavily shorted; tight-float names in this range have produced notable squeezes historically.
  • >30% — extreme; borrow is likely expensive and squeeze risk is material.
  • Days to Cover > 5 combined with high SI% amplifies squeeze potential.
History chart
  • Trend matters more than level. Rapidly rising short interest often precedes negative catalysts or heavy hedging.
  • A sudden drop in SI after a rally may indicate a squeeze in progress.

Short interest is reported mid-month and end-of-month; short volume is daily.

Short Interest
11.41M
SI % of Float
23.47%
Days to Cover
8.80
Short Vol Ratio
32.3%
Free Float
48.59M
Float %
90.6%
Short interest 2026-09-30 • Short volume 2026-10-26 • Float 2026-09-22