Invesco Biotechnology & Genome ETF(PBE · ETF)

ETF quote, holdings, sector allocation, technicals, and options analytics.

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.

PBE $97.26 —
Snapshot
$97.26
After hours $97.26 +0.00%
52-Week Range
$67.69 – $98.82
YTD
+18.11%
IV Rank (30D)
17.47
Straddle Price
$4.30
Info

Invesco Biotechnology & Genome ETF (PBE) ETF

Exchange
ARCX
Inception
2005-06-23
Has Options
Yes
ETF Profile
holdings as of 2026-09-23
Holdings
34
AUM
$419.8M
Provider
Invesco
Inception
2005-06-23
Exchange
ARCX
Data As Of
2026-09-23
Expense Ratio
—
Dividend Yield
1.37%
Distribution
Quarterly
Recent distributions
Ex-Date Pay Date Amount Type
2026-09-21 2026-09-25 $0.0187 CD
2026-06-22 2026-06-26 $0.8106 CD
2026-03-23 2026-03-27 $0.0824 CD
2025-12-22 2025-12-26 $0.4197 CD
2025-09-22 2025-09-26 $0.2341 CD
2025-06-23 2025-06-27 $0.1305 CD
Asset Allocation
Top Holdings
top 33 of 34 holdings
Symbol Name Weight % Asset Class Country
NTRA Natera Inc 5.95% Equity (US) US
ILMN Illumina Inc 5.82% Equity (US) US
BIIB Biogen Inc 5.28% Equity (US) US
GILD Gilead Sciences Inc 5.24% Equity (US) US
REGN Regeneron Pharmaceuticals Inc 4.93% Equity (US) US
VRTX Vertex Pharmaceuticals Inc 4.79% Equity (US) US
RPRX Royalty Pharma PLC 4.76% Equity (US) —
AMGN Amgen Inc 4.71% Equity (US) US
MRNA Moderna Inc 3.20% Equity (US) US
NVAX Novavax Inc 3.12% Equity (US) US
HALO Halozyme Therapeutics Inc 2.87% Equity (US) US
RGEN Repligen Corp 2.84% Equity (US) US
TGTX TG Therapeutics Inc 2.82% Equity (US) US
SRPT Sarepta Therapeutics Inc 2.80% Equity (US) US
QGEN QIAGEN NV 2.80% Equity (US) —
EXEL Exelixis Inc 2.80% Equity (US) US
VCYT Veracyte Inc 2.78% Equity (US) US
INCY Incyte Corp 2.69% Equity (US) US
UTHR United Therapeutics Corp 2.64% Equity (US) US
BMRN BioMarin Pharmaceutical Inc 2.63% Equity (US) US
PTGX Protagonist Therapeutics Inc 2.57% Equity (US) US
ARDX Ardelyx Inc 2.57% Equity (US) US
NBIX Neurocrine Biosciences Inc 2.54% Equity (US) US
VCEL Vericel Corp 2.51% Equity (US) US
BCRX BioCryst Pharmaceuticals Inc 2.44% Equity (US) US
ANAB AnaptysBio Inc 2.43% Equity (US) US
LEGN Legend Biotech Corp 2.42% Cash/Money Market —
PTCT PTC Therapeutics Inc 2.37% Equity (US) US
ACAD ACADIA Pharmaceuticals Inc 2.33% Equity (US) US
COLL Collegium Pharmaceutical Inc 2.28% Equity (US) US
AGPXX Invesco Government & Agency Portfolio 0.07% Cash/Money Market —
USD CASH & EQUIVALENTS 0.00% Other US
— SECURITIES LENDING - BNYM 0.00% Cash/Money Market —
Geographic Breakdown
Non-Equity Breakdown
Invesco Biotechnology & Genome ETF · NPORT-P period 2026-04-30 (filed 2026-03-30)
Net assets: $263M · 33 total positions · equity 100.01% · non-equity 14.17%
Non-equity holdings — 3 positions, 14.17% of NAV
Category Weight Value Positions
Short-term investment 14.17% $37.3M 3
Chart
Seasonality
MonthAvg ReturnYears of Data
Jan -0.10% 6
Feb -1.32% 6
Mar -2.15% 6
Apr -2.99% 6
May +1.32% 6
Jun +3.28% 6
Jul +3.13% 6
Aug +2.42% 6
Sep -3.22% 6
Oct +1.80% 5
Nov +3.23% 5
Dec +0.86% 5
Technical Indicators

Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.

Trend Indicators
  • SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
  • EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
  • MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
  • ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
  • +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
  • RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
  • Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
  • Williams %R — inverted scale: <−80 oversold, >−20 overbought.

Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.

Volume & Volatility
  • Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
  • OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
  • Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
  • ATR / True Range — average daily $ move; sizing and stop-loss reference.
  • HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.

Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →

Trend Indicators

SMA 20: $95.79
SMA 50: $94.22
SMA 200: $85.30
Current: $97.53
EMA 12: $96.07
EMA 26: $95.51
MACD: 0.5623 | Signal: 0.1561
BULLISH
ADX (14): 22.01
WEAK TREND
+DI: 28.85
−DI: 16.82

Momentum Oscillators

RSI (14): 58.12
NEUTRAL
Stoch %K: 79.16
Stoch %D: 73.69
Williams %R: -8.06

Volume & Volatility

BB Upper: $99.48
BB Lower: $92.10
NEUTRAL
OBV: 1,514,701
Vol SMA 20: 20,537
Vol ROC: -42.34%
ATR: $1.49
True Range: $1.40
HV 20: 21.8%
HV 30: 21.6%
HV 60: 19.7%

Data Summary

Data Points: 500
Last Updated:
Date Range: 2024-09-26T00:00:00 – 2026-09-24T00:00:00
AI Analysis

Here is a comprehensive stock analysis report for PBE (Invesco Biotechnology & Genome ETF) based on the provided technical indicators, options metrics, beta analysis, market data, and recent news headlines.

Executive Summary

Overall Assessment: NEUTRAL with confidence level 6/10

Key Drivers:

  • Bullish MACD signal indicating a trend reversal
  • RSI neutral at 58.27, suggesting no overbought or oversold conditions

Primary Risks:

  • Volatility regime indicates low volatility - stock moves less than market (Stock Volatility: 0.19)
  • Beta of 0.60 suggests PBE is relatively defensive compared to the broader market

Investment Thesis: PBE's recent trend reversal and neutral RSI suggest a balanced risk-reward profile. However, the low volatility regime and defensive beta may limit potential upside.

Recent News Sentiment Impact: NEUTRAL

Technical Analysis

Trend Direction:

  • Short-term (1-4 weeks): Bullish
  • Medium-term (1-3 months): Neutral
  • Long-term (3-12 months): Bearish

Support/Resistance Levels: PBE's recent high at $100.14 provides immediate resistance, while the 20-day SMA at $94.92 acts as support.

Momentum Signals:

  • RSI: 58.27 - neutral
  • MACD: Bullish signal above signal line (1.97 / 0.10)
  • Bollinger Bands: Neutral signal with no significant band breaches

Volume Analysis: PBE's volume SMA 20 at 58340.30 indicates a relatively stable trading environment.

News & Sentiment Analysis

Recent Headlines Summary: 6 recent news headlines all have neutral sentiment, discussing PBE as a health care ETF or comparing it to other biotech ETFs (VHT vs. PBE).

Sentiment Assessment: NEUTRAL

Catalyst Identification: No specific catalysts identified in recent news headlines.

Market Narrative: PBE's market narrative remains neutral due to the lack of significant news sentiment, which does not strongly contradict technical signals.

Risk & Volatility Assessment

Beta Interpretation: PBE's beta of 0.60 indicates a relatively defensive position compared to the broader market.

Volatility Regime: Low volatility regime suggests PBE is less likely to experience large price swings.

Options Market Signals: IV rank at 92.1% (high) shows historical volatility, while the current IV at 66.7% and expected move at $4.92 indicate a relatively calm options market.

Downside Protection: Support levels at 20-day SMA ($94.92) and Bollinger Bands provide some downside protection.

Market Context & Positioning

Sector Performance: PBE's health care sector performance is neutral, moving in line with the broader market.

Institutional Activity: No significant institutional activity flags are present.

Correlation Analysis: PBE's correlation with SPY at 0.40 indicates a relatively low relationship between the two assets.

Relative Valuation: PBE trades within its historical range, indicating no significant relative undervaluation or overvaluation.

Key Levels & Action Items

Critical Price Levels:

  • Resistance: $100.14
  • Support: $94.92

Breakout/Breakdown Levels:

  • Breakout above $100.14 would suggest a strong bullish trend
  • Breakdown below $94.92 could indicate a bearish reversal

Time-Sensitive Catalysts: No specific catalysts identified in recent news headlines.

Risk Management: Stop-loss levels should be set around $96.51, with position sizing considerations based on the expected move of $4.92.

Please let me know if you would like me to revise or expand this analysis in any way!

Generated
News
Options Activity
IV Rank (30D)
17.47
IV Rank (7D)
17.47
Avg IV
30.5%
Straddle (30D)
$4.30
Straddle (7D)
$4.30
Spread Scanner GPU

Each spread is ranked by a composite score built in three stages. Full documentation →

Stage 1 — Base Score (GPU scanner)

score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.

Stage 2 — Skew Adjustment (±25% cap)

RR and BF (30-delta) from the persisted per-symbol skew snapshot — wing strikes picked by real greeks.delta, not a moneyness proxy. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.

Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
  • RSI <40 bullish / >60 bearish
  • MACD crossover + histogram trend
  • Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
  • Stochastic %K <20 / >80
  • Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
  • Blended ATR + straddle expected-move penalty
  • Bollinger Band signal (+ counter-trend penalty)
  • BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
  • IV rank ≥ 75 → strong boost for credit spreads
  • IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
  • Min open interest across all legs
  • OI < 100 → −0.10 · OI < 500 → −0.05

score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →

Enter a ticker to scan for optimal spread opportunities.

Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.

Skew (Wing IV − ATM IV)
DTE:
Wing Δ:
Metric:
Wing vs ATM
IV(put wing) − IV(ATM), in vol points

How much the OTM put trades above (or below) the at-the-money strike. Measures the height of the put-side tail relative to ATM — i.e. how expensive crash insurance is on this name.

  • Positive (typical) — wing IV > ATM IV. Standard equity put skew: portfolios bid up crash protection, so OTM puts trade richer than ATM.
  • Near zero or negative (unusual) — wing IV ≤ ATM IV. Flat or inverted put side. Common when there's no fear demand, in tightly mean-reverting names, or right after an earnings catalyst clears.
  • Percentile vs own 3-yr history: high = wings rich (good time to sell wing premium); low = wings cheap (good time to buy protection).
  • Not directional — high or low wings don't predict up or down moves. It's a price tag on tail insurance, not a forecast.
Risk Reversal
IV(call wing) − IV(put wing), equal delta on each side

Which side of the smile is the market paying up for? Measures the tilt of the surface — call skew vs put skew at matched deltas.

  • Negative (typical) — puts richer than calls. Standard equity behavior: hedging demand makes puts carry a premium. Most large-caps sit in the −1 to −5 vol-point range.
  • Strongly negative (< −5 pts) — heavy downside hedging, elevated fear, or an upcoming catalyst (earnings, FDA, macro event). Worth flagging.
  • Positive — calls richer than puts. Unusual for equities; signals bullish momentum, short-squeeze positioning, or takeover/M&A speculation.
  • Near zero — symmetric surface. Market sees roughly equal up/down risk. Rare for large-caps; more common in commodities and FX.
Reading them together

Wing-vs-ATM tells you how expensive the tails are. Risk Reversal tells you which side is favored. Combined:

  • High wing percentile + deeply negative RR → strong put bid; stress or major event priced in. Owning protection costs a premium; selling put premium is dangerous.
  • Low wing percentile + near-zero RR → complacency; insurance cheap and balanced. Good environment to add cheap downside hedges.
  • Positive RR + elevated wings → call-side fear-of-missing-out; common in squeeze setups. Upside calls expensive, downside puts not bid.
14 DTE / 10d —
— pts EXTREME
ATM — / Wing —
30 DTE / 10d —
— pts EXTREME
ATM — / Wing —

Percentile is the rank of today's reading within ~3 years of this symbol's own history. High percentile = wings are rich relative to history; not a directional signal. Skew is read off the chain in real time, not from CBOE SKEW.

Volatility Surface

Enter a ticker to render the implied volatility surface.

Volatility Smile

Enter a ticker to render the implied volatility smile.

IV Rank (7 DTE)
IV Rank (30 DTE)
Straddle Price (30 DTE)
Beta Analysis
Beta (1Y vs SPY)
0.64
Correlation (SPY)
43.6%
R²
0.19
Ann. Volatility
19.0%
SPY Volatility
13.0%

Low volatility - stock moves less than market

Beta & Alpha Over Time
Constituent Performance

Click any bar to view the full quote for that stock.

Constituents
Symbol Name Weight % Price 1 Day 1 Week 1 Month