Spruce Biosciences, Inc. Common Stock (SPRB) Stock Quote & Options Analysis | Frenzy Capital

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.

Snapshot
$78.74
After hours $53.78 +0.00%
52-Week Range
$7.26 – $240.00
YTD
-13.19%
IV Rank (30D)
0.0
Straddle Price
$6.25
P/C Vol Ratio
0.00
Market Cap
$0.2B
Info
Industry (SIC)
PHARMACEUTICAL PREPARATIONS (2834)
Exchange
XNAS
Market Cap
$0.2B

Spruce Biosciences Inc is a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare endocrine disorders with unmet medical needs. The company develops biologics and small-molecule product candidates aimed at addressing diseases with unmet medical needs and limited or no approved therapies. Its product candidate, TA-ERT for the treatment of Mucopolysaccharidosis Type IIIB (MPS IIIB), is a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase (rhNAGLU) intended as an enzyme replacement therapy for patients who lack rhNAGLU enz…

Price History
Seasonality
MonthAvg ReturnYears of Data
Jan +22.30% 6
Feb -4.78% 6
Mar -14.85% 6
Apr -14.02% 6
May -1.79% 5
Jun -12.37% 4
Jul -2.02% 4
Aug -3.49% 4
Sep -14.90% 5
Oct +208.54% 5
Nov -9.37% 5
Dec +28.61% 5
Technical Indicators

Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.

Trend Indicators
  • SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
  • EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
  • MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
  • ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
  • +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
  • RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
  • Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
  • Williams %R — inverted scale: <−80 oversold, >−20 overbought.

Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.

Volume & Volatility
  • Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
  • OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
  • Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
  • ATR / True Range — average daily $ move; sizing and stop-loss reference.
  • HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.

Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →

Trend Indicators
SMA 20: $56.87
SMA 50: $61.03
SMA 200: $68.48
Current: $53.78
EMA 12: $57.13
EMA 26: $58.65
MACD: -1.5201 | Signal: 0.0621
BEARISH
ADX (14): 14.91
RANGE
+DI: 16.06
−DI: 25.94
Momentum Oscillators
RSI (14): 40.42
NEUTRAL
Stoch %K: 49.08
Stoch %D: 56.74
Williams %R: -93.11
Volume & Volatility
BB Upper: $64.17
BB Lower: $49.57
NEUTRAL
OBV: 23,700,748
Vol SMA 20: 86,777
Vol ROC: 60.76%
ATR: $4.18
True Range: $5.70
HV 20: 118.7%
HV 30: 105.5%
HV 60: 99.5%

Data Summary
Data Points: 500
Last Updated: 2026-05-15T21:15:18.211000
Date Range: 2024-01-02T00:00:00 – 2026-05-15T00:00:00
AI Analysis

Choose Frenzy-Fast™ for quick analysis or Frenzy-Pro™ for comprehensive analysis.

Analysis includes technical indicators, news sentiment, risk assessment, and specific price levels to watch.

News
Options Activity
IV Rank (30D)
0.0
IV Rank (7D)
0.0
Avg IV
0.0%
Straddle (30D)
$6.25
Straddle (7D)
$6.25
P/C Volume
0.00
Spread Scanner GPU

Each spread is ranked by a composite score built in three stages. Full documentation →

Stage 1 — Base Score (GPU scanner)

score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.

Stage 2 — Skew Adjustment (±25% cap)

RR25 and BF25 from the live options chain. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.

Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
  • RSI <40 bullish / >60 bearish
  • MACD crossover + histogram trend
  • Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
  • Stochastic %K <20 / >80
  • Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
  • Blended ATR + straddle expected-move penalty
  • Bollinger Band signal (+ counter-trend penalty)
  • BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
  • IV rank ≥ 75 → strong boost for credit spreads
  • IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
  • Min open interest across all legs
  • OI < 100 → −0.10 · OI < 500 → −0.05

score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →

Enter a ticker to scan for optimal spread opportunities.

Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.

Volatility Surface

Enter a ticker to render the implied volatility surface.

IV Rank (7 DTE)
IV Rank (30 DTE)
Straddle Price (30 DTE)
Beta Analysis
Beta (1Y vs SPY)
4.98
Correlation (SPY)
3.8%
0.00
Ann. Volatility
1689.1%
SPY Volatility
13.0%

High volatility - stock moves more than market

Beta & Alpha Over Time
Institutional Ownership (13F)
Latest filings — 2026-03-31

Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.

  • Shares — long equity positions in this name, aggregated across share classes.
  • Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
  • % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
  • Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.

Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.

34 filers767,674 shares$64.40M value
# Filer Shares Value % of Total % of Float Period
1 Ikarian Capital, LLC 121,356 $10.57M 16.42% 2025-12-31
2 Squadron Capital Management LLC 70,000 $6.10M 9.47% 2025-12-31
3 CITADEL ADVISORS LLC Custodian 69,999 $6.10M 9.47% 2025-12-31
4 WELLINGTON MANAGEMENT GROUP LLP Custodian 58,949 $5.14M 7.97% 2025-12-31
5 ADAR1 Capital Management, LLC 58,000 $5.05M 7.85% 2025-12-31
6 Alyeska Investment Group, L.P. 51,671 $4.50M 6.99% 2025-12-31
7 BOOTHBAY FUND MANAGEMENT, LLC 47,933 $4.18M 6.48% 2025-12-31
8 BALYASNY ASSET MANAGEMENT L.P. 40,000 $3.48M 5.41% 2025-12-31
9 Carlyle Group Inc. 38,620 $2.52M 3.92% 2026-03-31
10 ExodusPoint Capital Management, LP 25,271 $2.20M 3.42% 2025-12-31
11 Schonfeld Strategic Advisors LLC 24,767 $2.16M 3.35% 2025-12-31
12 Quinn Opportunity Partners LLC 22,810 $1.99M 3.09% 2025-12-31
13 Caligan Partners LP 20,514 $1.79M 2.77% 2025-12-31
14 Stonepine Capital Management, LLC 19,742 $1.72M 2.67% 2025-12-31
15 VANGUARD GROUP INC Custodian 17,873 $1.56M 2.42% 2025-12-31
16 BlackRock, Inc. Custodian 16,938 $1.48M 2.29% 2025-12-31
17 GEODE CAPITAL MANAGEMENT, LLC Custodian 12,732 $1.11M 1.72% 2025-12-31
18 SUPERSTRING CAPITAL MANAGEMENT LP 12,137 $1.06M 1.64% 2025-12-31
19 STATE STREET CORP 6,400 $557.50K 0.87% 2025-12-31
20 Resolute Capital Asset Partners LLC 4,000 $348.44K 0.54% 2025-12-31
21 UBS Group AG Custodian 3,919 $256.11K 0.40% 2026-03-31
22 NORTHERN TRUST CORP Custodian 2,422 $210.98K 0.33% 2025-12-31
23 BNP PARIBAS FINANCIAL MARKETS Custodian 2,000 $174.22K 0.27% 2025-12-31
24 Lion Point Capital, LP 1,000 $87.11K 0.14% 2025-12-31
25 MORGAN STANLEY Custodian 388 $33.80K 0.05% 2025-12-31
# Filer Notional Value % of Total Period
# Filer Notional Value % of Total Period
Fundamentals

Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.

Metrics
  • Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
  • Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
  • Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
  • Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
How to read the bars
  • Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
  • YoY growth — compare to the same quarter a year earlier to remove seasonality.
  • Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
  • Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.

TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.