Protalix BioTherapeutics, Inc. Common Stock(PLX)

Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership.

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.

Snapshot
$2.22
52-Week Range
$1.32 – $3.19
YTD
+27.59%
IV Rank (30D)
67.85
Straddle Price
$0.53
P/C Vol Ratio
0.00
Market Cap
$0.2B
Fair Value
+50.0% vs price
Confidence: 15% Alpha Score: 6.19

A blended fair-value estimate combining up to six valuation methods. Each method is weighted by how well it fits the company — DCF down-weights for unprofitable names; DDM only fires for steady dividend payers; comparables down-weight when peer multiples disagree.

  • DCF (quality-aware) — projects free cash flow with a horizon that scales to business quality. True compounders (quality 6/6) get 10 years explicit + 10 years fade before terminal; cyclical/struggling names (quality 0-1) get a 5-year terminal cliff. Quality is scored from ROE, gross margin, growth, FCF margin, debt load, and FCF consistency — the same factors that drive market premium for compounders.
  • Market-Implied Growth (in Model Inputs) — reverse-DCF that answers "what growth rate is the market pricing in?". Lets you sanity-check the deviation: if implied growth is plausible for the business, the model's bearish flag may be wrong; if implausible, the market may be over-extrapolating.
  • DDM (Gordon Growth Dividend Model) — values the stream of future dividends. Only used when trailing yield ≥ 0.5% and dividend payments are stable.
  • P/E, EV/EBITDA, P/B, P/S — applies the peer-group median multiple to this company's per-share metric. Peers come from the same set as the "Related symbols" card. Earnings/sales metrics are forward-tilted by the company's recent revenue growth (capped at 25%) so they're comparable to peers' growth-embedded multiples — mimics how analysts use NTM rather than TTM. Per-multiple weights are biased by company quality (e.g. P/B down-weighted for asset-light tech).
  • Market Anchor (SMA50) — the 50-day moving average, weighted by recent trading-range stability (tighter Bollinger bands → higher weight). Captures information fundamentals miss (forward consensus, sentiment, supply/demand) — but only when recent trading is steady enough that the market has converged on a view. During wild breakouts or breakdowns the anchor's weight collapses.
  • Options Expected (B-L 30d) — the risk-neutral expected stock price at 30-day options expiration, derived from the full implied-volatility surface via Breeden-Litzenberger (second derivative of call price wrt strike → implied PDF, then E[S_T]). Forward-looking, captures all options-implied information (smile, skew, term structure) in one number. Weighted by chain liquidity. SP500-only at present (pre-computed daily). Backtest evidence: adds modest alpha across most bucket × holding combos.
  • Blended value — weighted average. Confidence reflects how many methods fired and how tight peer dispersion is.
  • Deviation pill — green when blended FV ≥ 10% above current price (undervalued); red when ≥ 10% below; grey otherwise.
10-yr Treasury (rf)4.43%
Beta vs SPY0.88
Cost of Equity (CAPM)8.85% (VRP-adj)
WACC9.61%
Volatility Risk Premium+144.8pp (IV − HV30)
Effective Tax Rate20.4%
Rev. Growth (YoY, DCF input)+30.0%
DCF Horizon12 years explicit + fade
Forward Tilt (NTM/TTM)×1.10 (applied to P/E, EV/EBITDA, P/S)
Free Cash Flow (TTM)$0.0B
Return on Equity (TTM)22.8%
Book / Price37.4% — banking bias active (P/B is primary)
Gross Margin (TTM)70.0%
FCF Margin (TTM)17.0%
Debt / Equity0.00
Quality Score5/6 — high quality (12y DCF)
Market-Implied Growth-2.3% (reverse-DCF on current price)
SMA 50$2.09 (Market Anchor value)
SMA 20 / Bollinger Mid$2.05
Bollinger Width / SMA20637.8% (drives anchor stability)
Net Debt$-0.0B
Market Cap$0B
Peers used for multiples: BIIB, MRNA, NBIX (filtered from 8 ETF-co-members; sector bias active)
Blended Fair Value
$9.64
Current Price
$2.22
Deviation
+50.0%
MethodImplied PriceWeightDetail
DCF $13.46 56%
DDM (Gordon) n/a 0%
Peer P/E n/a 0%
Peer EV/EBITDA n/a 0%
Peer P/B $2.75 10% median 3.3× · 3 peers
Peer P/S $5.35 34% median 5.2× · 3 peers
Market Anchor (SMA50) $2.09 0% stability 0% (BB-width)
Options Expected (B-L 30d) n/a 0%
As of 2026-06-19 · updated 2026-06-19 21:00:06.101000
Info
Industry (SIC)
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES) (2836)
Exchange
XASE
Market Cap
$0.2B

Protalix BioTherapeutics Inc is a commercial-stage biopharmaceutical company focused on the discovery, development, production, and commercialization of therapeutics for rare diseases with important unmet needs. ProCellEx, a proprietary plant cell-based protein expression system, represents a new method for developing recombinant proteins in an industrial-scale manner. corporate includes the development of treatments for rare and orphan diseases. The Company operates as a single operating segment in Israel.

Chart
Seasonality
MonthAvg ReturnYears of Data
Jan +8.32% 20
Feb +5.36% 20
Mar -1.07% 21
Apr +5.05% 21
May -4.33% 21
Jun -4.73% 21
Jul -4.00% 20
Aug -1.31% 19
Sep +5.25% 19
Oct -6.45% 19
Nov -1.12% 19
Dec -1.29% 19
Technical Indicators

Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.

Trend Indicators
  • SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
  • EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
  • MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
  • ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
  • +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
  • RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
  • Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
  • Williams %R — inverted scale: <−80 oversold, >−20 overbought.

Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.

Volume & Volatility
  • Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
  • OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
  • Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
  • ATR / True Range — average daily $ move; sizing and stop-loss reference.
  • HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.

Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →

Trend Indicators
SMA 20: $2.05
SMA 50: $2.09
SMA 200: $2.18
Current: $2.22
EMA 12: $2.06
EMA 26: $2.06
MACD: 0.0045 | Signal: 0.0206
BEARISH
ADX (14): 15.15
RANGE
+DI: 28.31
−DI: 16.44
Momentum Oscillators
RSI (14): 62.90
NEUTRAL
Stoch %K: 61.53
Stoch %D: 52.79
Williams %R: -1.79
Volume & Volatility
BB Upper: $2.19
BB Lower: $1.92
OVERBOUGHT
OBV: 13,962,794
Vol SMA 20: 669,104
Vol ROC: 206.83%
ATR: $0.09
True Range: $0.21
HV 20: 45.9%
HV 30: 44.8%
HV 60: 42.9%

Data Summary
Data Points: 500
Last Updated: 2026-06-19T21:15:20.690000
Date Range: 2024-06-21T00:00:00 – 2026-06-18T00:00:00
AI Analysis

Choose Frenzy-Fast™ for quick analysis or Frenzy-Pro™ for comprehensive analysis.

Analysis includes technical indicators, news sentiment, risk assessment, and specific price levels to watch.

News
Earnings History
6 of 8 under expected move
Each row pairs the pre-earnings straddle-implied expected move with the realized close-to-close move. Sorted oldest first.
Earnings Date Timing Expected Move Actual Move Ratio Outcome
2024-08-14 Pre-Market 211.54% 8.66% 0.04x Within
2024-11-14 Pre-Market 18.15% 17.74% 0.98x Within
2025-03-17 Pre-Market 24.44% 5.04% 0.21x Within
2025-05-09 Pre-Market 16.47% 40.18% 2.44x Exceeded
2025-08-14 Pre-Market 139.75% 5.59% 0.04x Within
2025-11-13 Pre-Market 29.21% 10.28% 0.35x Within
2026-03-18 Pre-Market 17.76% 21.31% 1.20x Exceeded
2026-05-13 Pre-Market 14.40% 1.05% 0.07x Within
Options Activity
IV Rank (30D)
67.85
IV Rank (7D)
100
Avg IV
189.6%
Straddle (30D)
$0.53
Straddle (7D)
$0.17
P/C Volume
0.00
Spread Scanner GPU

Each spread is ranked by a composite score built in three stages. Full documentation →

Stage 1 — Base Score (GPU scanner)

score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.

Stage 2 — Skew Adjustment (±25% cap)

RR and BF (30-delta) from the persisted per-symbol skew snapshot — wing strikes picked by real greeks.delta, not a moneyness proxy. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.

Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
  • RSI <40 bullish / >60 bearish
  • MACD crossover + histogram trend
  • Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
  • Stochastic %K <20 / >80
  • Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
  • Blended ATR + straddle expected-move penalty
  • Bollinger Band signal (+ counter-trend penalty)
  • BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
  • IV rank ≥ 75 → strong boost for credit spreads
  • IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
  • Min open interest across all legs
  • OI < 100 → −0.10 · OI < 500 → −0.05

score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →

Enter a ticker to scan for optimal spread opportunities.

Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.

Skew (Wing IV − ATM IV)
DTE:
Wing Δ:
Metric:
Wing vs ATM
IV(put wing) − IV(ATM), in vol points

How much the OTM put trades above (or below) the at-the-money strike. Measures the height of the put-side tail relative to ATM — i.e. how expensive crash insurance is on this name.

  • Positive (typical) — wing IV > ATM IV. Standard equity put skew: portfolios bid up crash protection, so OTM puts trade richer than ATM.
  • Near zero or negative (unusual) — wing IV ≤ ATM IV. Flat or inverted put side. Common when there's no fear demand, in tightly mean-reverting names, or right after an earnings catalyst clears.
  • Percentile vs own 3-yr history: high = wings rich (good time to sell wing premium); low = wings cheap (good time to buy protection).
  • Not directional — high or low wings don't predict up or down moves. It's a price tag on tail insurance, not a forecast.
Risk Reversal
IV(call wing) − IV(put wing), equal delta on each side

Which side of the smile is the market paying up for? Measures the tilt of the surface — call skew vs put skew at matched deltas.

  • Negative (typical) — puts richer than calls. Standard equity behavior: hedging demand makes puts carry a premium. Most large-caps sit in the −1 to −5 vol-point range.
  • Strongly negative (< −5 pts) — heavy downside hedging, elevated fear, or an upcoming catalyst (earnings, FDA, macro event). Worth flagging.
  • Positive — calls richer than puts. Unusual for equities; signals bullish momentum, short-squeeze positioning, or takeover/M&A speculation.
  • Near zero — symmetric surface. Market sees roughly equal up/down risk. Rare for large-caps; more common in commodities and FX.
Reading them together

Wing-vs-ATM tells you how expensive the tails are. Risk Reversal tells you which side is favored. Combined:

  • High wing percentile + deeply negative RR → strong put bid; stress or major event priced in. Owning protection costs a premium; selling put premium is dangerous.
  • Low wing percentile + near-zero RR → complacency; insurance cheap and balanced. Good environment to add cheap downside hedges.
  • Positive RR + elevated wings → call-side fear-of-missing-out; common in squeeze setups. Upside calls expensive, downside puts not bid.
14 DTE / 10d
pts EXTREME
ATM — / Wing —
30 DTE / 10d
pts EXTREME
ATM — / Wing —

Percentile is the rank of today's reading within ~3 years of this symbol's own history. High percentile = wings are rich relative to history; not a directional signal. Skew is read off the chain in real time, not from CBOE SKEW.

Volatility Surface

Enter a ticker to render the implied volatility surface.

Volatility Smile

Enter a ticker to render the implied volatility smile.

IV Rank (7 DTE)
IV Rank (30 DTE)
Straddle Price (30 DTE)
Beta Analysis
Beta (1Y vs SPY)
1.71
Correlation (SPY)
31.7%
0.10
Ann. Volatility
66.9%
SPY Volatility
12.4%

High volatility - stock moves more than market

Beta & Alpha Over Time
Institutional Ownership (13F)
Latest filings — 2026-03-31
Diluted shares outstanding: 80,920,251 (as of 2026-03-31)

Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.

  • Shares — long equity positions in this name, aggregated across share classes.
  • Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
  • % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
  • Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.

Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.

98 filers18,817,942 shares$39.22M value23.25% of float
# Filer Shares Value % of Total % of Float Period
1 BlackRock, Inc. Custodian 3,616,962 $7.85M 20.01% 4.47% 2026-03-31
2 MAK CAPITAL ONE LLC 3,544,139 $7.69M 19.61% 4.38% 2026-03-31
3 Opaleye Management Inc. 2,478,176 $4.46M 11.37% 3.06% 2025-12-31
4 RENAISSANCE TECHNOLOGIES LLC 1,224,800 $2.66M 6.78% 1.51% 2026-03-31
5 STATE STREET CORP 972,815 $2.11M 5.38% 1.20% 2026-03-31
6 NORTHERN TRUST CORP Custodian 885,448 $1.92M 4.90% 1.09% 2026-03-31
7 GEODE CAPITAL MANAGEMENT, LLC Custodian 865,298 $1.88M 4.79% 1.07% 2026-03-31
8 Stratos Wealth Partners, LTD. 500,000 $1.08M 2.77% 0.62% 2026-03-31
9 Prospera Financial Services Inc 418,570 $908.27K 2.32% 0.52% 2026-03-31
10 VANGUARD GROUP INC Custodian 488,552 $879.39K 2.24% 0.60% 2025-12-31
11 DIMENSIONAL FUND ADVISORS LP Custodian 296,843 $643.79K 1.64% 0.37% 2026-03-31
12 UBS Group AG Custodian 265,535 $576.21K 1.47% 0.33% 2026-03-31
13 GOLDMAN SACHS GROUP INC Custodian 251,345 $545.42K 1.39% 0.31% 2026-03-31
14 Bank of New York Mellon Corp Custodian 219,307 $475.90K 1.21% 0.27% 2026-03-31
15 Connor, Clark & Lunn Investment Management Ltd. 207,275 $449.79K 1.15% 0.26% 2026-03-31
16 BRIDGEWAY CAPITAL MANAGEMENT, LLC 189,100 $410.35K 1.05% 0.23% 2026-03-31
17 Main Street Financial Solutions, LLC 214,100 $385.38K 0.98% 0.26% 2025-12-31
18 EVERGREEN CAPITAL MANAGEMENT LLC 171,338 $371.80K 0.95% 0.21% 2026-03-31
19 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 159,311 $345.70K 0.88% 0.20% 2026-03-31
20 Round Rock Advisors LLC 155,102 $279.18K 0.71% 0.19% 2025-12-31
21 Diametric Capital, LP 124,195 $269.50K 0.69% 0.15% 2026-03-31
22 MORGAN STANLEY Custodian 131,987 $237.58K 0.61% 0.16% 2025-12-31
23 Nuveen, LLC Custodian 90,188 $195.71K 0.50% 0.11% 2026-03-31
24 LAZARD ASSET MANAGEMENT LLC 86,617 $187.96K 0.48% 0.11% 2026-03-31
25 BANK OF AMERICA CORP /DE/ Custodian 79,079 $171.60K 0.44% 0.10% 2026-03-31
5 filers$651.00K notional
# Filer Notional Value % of Total Period
1 SUSQUEHANNA INTERNATIONAL GROUP, LLP Custodian $383.22K 58.87% 2026-03-31
2 JANE STREET GROUP, LLC Custodian $125.86K 19.33% 2026-03-31
3 CITADEL ADVISORS LLC Custodian $56.20K 8.63% 2026-03-31
4 SIMPLEX TRADING, LLC Custodian $54.47K 8.37% 2026-03-31
5 GROUP ONE TRADING LLC Custodian $31.25K 4.80% 2026-03-31
6 filers$453.85K notional
# Filer Notional Value % of Total Period
1 SUSQUEHANNA INTERNATIONAL GROUP, LLP Custodian $129.55K 28.54% 2026-03-31
2 CITADEL ADVISORS LLC Custodian $94.83K 20.89% 2026-03-31
3 WOLVERINE TRADING, LLC Custodian $70.85K 15.61% 2025-09-30
4 JANE STREET GROUP, LLC Custodian $68.79K 15.16% 2026-03-31
5 SIMPLEX TRADING, LLC Custodian $56.42K 12.43% 2026-03-31
6 GROUP ONE TRADING LLC Custodian $33.42K 7.36% 2026-03-31
Insider Activity
Latest: 2025-12-23
Form 4 filings — insider beneficial-ownership changes by officers, directors, and 10%+ holders. Filed within 2 business days of transaction.
Filed Reporter Role Action Shares Avg Price Net $ Link
2025-12-23 Dror Bashan PRESIDENT AND CEO Buy (P) +56,000 $1.81 $101.4K EDGAR
2025-11-19 Amos Bar-Shalev Director Sell (S) −168 $1.87 -$314 EDGAR
2025-09-04 Gwen A Melincoff Director Award (A) +7,500 EDGAR
2025-09-04 Christian Elze Director Award (A) +7,500 EDGAR
2025-09-04 Zvi Shmuel Ben Director Award (A) +7,500 EDGAR
2025-09-04 Aharon Schwartz Director Award (A) +7,500 EDGAR
2025-09-04 Amos Bar-Shalev Director Award (A) +7,500 EDGAR
2025-09-04 Pol F Boudes Director Award (A) +7,500 EDGAR
2025-09-04 Dror Bashan PRESIDENT AND CEO Award (A) +195,000 EDGAR
2025-09-04 Yaron Naos Sr. VP, Operations Award (A) +25,000 EDGAR
2025-09-04 Eliot Forster Director Award (A) +7,500 EDGAR
2025-08-12 Aharon Schwartz Director Buy (P) +129,000 $1.60 $205.9K EDGAR
2024-11-05 Eyal Rubin Sr. VP and CFO Award (A) +90,909 EDGAR
2024-09-24 Yaron Naos Sr. VP, Operations Grant (A) +100,000 opt EDGAR
2024-09-24 Eyal Rubin Sr. VP and CFO Award (A) +99,010 EDGAR
Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (described in filing footnote — typically 401(k), trust, inheritance) · W = will/inheritance. Only P / S codes carry directional signal.
Insider Holdings
26 insiders · @ $2.22
Officers, directors, and 10%+ owners ranked by current disclosed exposure (shares × today's price). Shares are direct + indirect (via trusts / LLCs / spouse). Excludes unvested RSU and option grants — those aren't beneficially owned until vest.
# Insider Role Shares Disclosed Exposure Lifetime OM Net Filings Last Filed
1 Camber Capital Management LP 10%+ Owner 10,775,000 $23.92M $3.21M 2 2016-12-06
2 Frost Gamma Investments Trust 10%+ Owner 7,944,081 $17.64M -$16.06M 9 2009-08-26
3 PHILLIP MD ET AL FROST 10%+ Owner 7,704,187 $17.10M -$11.55M 8 2009-09-11
4 Eli Hurvitz Director 5,354,222 $11.89M -$13.91M 1 2009-11-13
5 Alfred Akirov Director 4,927,713 $10.94M -$903.3K 4 2013-08-16
6 Dexcel Pharma Technologies Ltd. 10%+ Owner 4,494,820 $9.98M -$4.18M 1 2021-06-03
7 Dror Bashan PRESIDENT AND CEO 2,532,934 $5.62M $293.8K 11 2025-12-23
8 Zeev Bronfeld Director 2,162,481 $4.80M -$10.87M 5 2022-09-09
9 Bio-Cell Ltd 10%+ Owner 1,509,948 $3.35M -$10.87M 2 2014-09-18
10 Yoseph Shaaltiel Executive VP, R&D 795,916 $1.77M -$7.14M 19 2018-09-14
Lifetime OM Net = signed sum of open-market buys (P) and sells (S) over their career; excludes grants, tax withholdings, and dispositions to issuer. A large negative number is normal for long-tenured executives — they've sold compensation grants over many years.
ETF Holders
# ETF Provider Weight $ Exposure ETF AUM As Of
Fundamentals

Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.

Metrics
  • Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
  • Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
  • Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
  • Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
How to read the bars
  • Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
  • YoY growth — compare to the same quarter a year earlier to remove seasonality.
  • Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
  • Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.

TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.

P/E Ratio12.3
P/B Ratio2.7
P/S Ratio2.3
EV/EBITDA6.5
TTM Revenue$0.1B
TTM Net Income$0.0B
TTM EPS$0.18
ROE22.8%