ACORN CAPITAL ADVISORS, LLC — 13F Holdings & Portfolio

CIK 2054410 · latest 13F-HR filed 2026-05-15

ACORN CAPITAL ADVISORS, LLC manages $351.8M in 13F-reported U.S. long-equity assets across 22 reported positions as of its 2026-03-31 13F-HR filing. Its largest disclosed positions are TERN (26.17%), CGON (21.77%), URGN (8.55%). Quarter over quarter (versus its 2025-12-31 filing) the fund opened 2 new positions, exited 1, added to 10, and trimmed 7.

AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.

Loading holdings…
AUM

$351.8M

Long-equity book

Holdings

22

Distinct positions

Period

2026-03-31

Filed 2026-05-15

Q/Q Activity

+2 / −1 / ↑10 / ↓7

vs 2025-12-31

Firm Profile & Key People
Name Title / Status Ownership Type

Top Adds (vs prior quarter)

  • CG ONCOLOGY INC$29.6M +63.0%
  • TERNS PHARMACEUTICALS INC$21.5M +30.5%
  • ONKURE THERAPEUTICS INC$3.5M +42.8%
  • LEONABIO, INC.$2.7M +71.7%
  • CANDEL THERAPEUTICS INC$2.6M +18.0%
Show all 10

Top Trims

  • HELUS PHARMA INC.-$5.5M -42.6%
  • UROGEN PHARMA LTD-$3.8M -11.3%
  • VERASTEM INC-$3.6M -31.3%
  • CARDIF ONCOLOGY INC-$2.7M -48.2%
  • JASPER THERAPEUTICS-$2.0M -62.0%
Show all 7

New Positions

  • JADE BIOSCEINCES INC$11.1M
  • KARYOPHARM THERAPEUTICS INC$1.6M
Show all 2

Exited Positions

  • ACRIVON THERAPEUTICS INC$976.6K
Show all 1
All Holdings

Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).

# Issuer Symbol CUSIP Value Weight Shares Type
1 TERNS PHARMACEUTICALS INC TERN 880881107 $92.1M 26.17% 1,746,264 SH
2 CG ONCOLOGY INC CGON 156944100 $76.6M 21.77% 1,130,501 SH
3 UROGEN PHARMA LTD URGN M96088105 $30.1M 8.55% 1,673,420 SH
4 PUMA BIOTECHNOLOGY INC PBYI 74587V107 $26.4M 7.50% 4,131,299 SH
5 TREVI THERAPEUTICS INC TRVI 89532M101 $25.6M 7.27% 2,144,844 SH
6 CANDEL THERAPEUTICS INC CADL 137404109 $17.2M 4.89% 3,497,948 SH
7 BICARA THERAPEUTICS BCAX 055477103 $12.8M 3.64% 643,382 SH
8 ONKURE THERAPEUTICS INC OKUR 68277Q105 $11.8M 3.34% 2,839,674 SH
9 JADE BIOSCEINCES INC JBIO 008064206 $11.1M 3.14% 786,760 SH
10 PROTARA THERAPEUTICS INC TARA 74365U107 $9.1M 2.59% 1,752,115 SH
11 VERASTEM INC VSTM 92337C203 $7.8M 2.21% 1,469,153 SH
12 HELUS PHARMA INC. HELP 23256X407 $7.4M 2.10% 1,540,266 SH
13 LEONABIO, INC. LONA 04746L203 $6.5M 1.85% 634,539 SH
14 AURA BIOSCIENCES INC AURA 05153U107 $4.0M 1.13% 595,744 SH
15 WHITEHAWK THERAPEUTICS INC WHWK 00032Q104 $3.9M 1.12% 1,139,363 SH
16 CARDIF ONCOLOGY INC CRDF 14147L108 $2.9M 0.81% 1,762,084 SH
17 Q32 BIO INC. QTTB 746964105 $2.0M 0.57% 315,052 SH
18 KARYOPHARM THERAPEUTICS INC KPTI 48576U205 $1.6M 0.46% 287,826 SH
19 JASPER THERAPEUTICS JSPR 471871202 $1.2M 0.35% 1,411,492 SH
20 X4 PHARMACEUTICALS INC XFOR 98420X103 $966.6K 0.27% 234,039 SH
21 BIOATLA INC BCAB 09077B104 $865.0K 0.25% 5,406,345 SH
22 VYNE THERAPEUTICS INC VYNE 92941V308 $855 0.00% 1,425 SH
Filing History
Period Filed AUM Holdings Accession
2026-03-31 2026-05-15 $351.8M 22 0001636587-26-000029
2025-12-31 2026-02-17 $295.1M 21 0001636587-26-000005
2025-09-30 2025-11-17 $197.0M 20 0001636587-25-000060