OnKure Therapeutics, Inc. Class A Common Stock(OKUR)

Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership.

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.

Snapshot
$2.05
52-Week Range
$1.91 – $5.38
YTD
-30.74%
IV Rank (30D)
0
Straddle Price
$2.72
P/C Vol Ratio
1.00
Market Cap
$0.2B
Fair Value
+50.0% vs price
Confidence: 7% Alpha Score: 13.00

A blended fair-value estimate combining up to six valuation methods. Each method is weighted by how well it fits the company — DCF down-weights for unprofitable names; DDM only fires for steady dividend payers; comparables down-weight when peer multiples disagree.

  • DCF (quality-aware) — projects free cash flow with a horizon that scales to business quality. True compounders (quality 6/6) get 10 years explicit + 10 years fade before terminal; cyclical/struggling names (quality 0-1) get a 5-year terminal cliff. Quality is scored from ROE, gross margin, growth, FCF margin, debt load, and FCF consistency — the same factors that drive market premium for compounders.
  • Market-Implied Growth (in Model Inputs) — reverse-DCF that answers "what growth rate is the market pricing in?". Lets you sanity-check the deviation: if implied growth is plausible for the business, the model's bearish flag may be wrong; if implausible, the market may be over-extrapolating.
  • DDM (Gordon Growth Dividend Model) — values the stream of future dividends. Only used when trailing yield ≥ 0.5% and dividend payments are stable.
  • P/E, EV/EBITDA, P/B, P/S — applies the peer-group median multiple to this company's per-share metric. Peers come from the same set as the "Related symbols" card. Earnings/sales metrics are forward-tilted by the company's recent revenue growth (capped at 25%) so they're comparable to peers' growth-embedded multiples — mimics how analysts use NTM rather than TTM. Per-multiple weights are biased by company quality (e.g. P/B down-weighted for asset-light tech).
  • Market Anchor (SMA50) — the 50-day moving average, weighted by recent trading-range stability (tighter Bollinger bands → higher weight). Captures information fundamentals miss (forward consensus, sentiment, supply/demand) — but only when recent trading is steady enough that the market has converged on a view. During wild breakouts or breakdowns the anchor's weight collapses.
  • Options Expected (B-L 30d) — the risk-neutral expected stock price at 30-day options expiration, derived from the full implied-volatility surface via Breeden-Litzenberger (second derivative of call price wrt strike → implied PDF, then E[S_T]). Forward-looking, captures all options-implied information (smile, skew, term structure) in one number. Weighted by chain liquidity. SP500-only at present (pre-computed daily). Backtest evidence: adds modest alpha across most bucket × holding combos.
  • Blended value — weighted average. Confidence reflects how many methods fired and how tight peer dispersion is.
  • Deviation pill — green when blended FV ≥ 10% above current price (undervalued); red when ≥ 10% below; grey otherwise.
10-yr Treasury (rf)4.50%
Beta vs SPY1.00
Cost of Equity (CAPM)9.50%
WACC9.55%
Effective Tax Rate21.0%
Rev. Growth (YoY, DCF input)+3.0%
DCF Horizon5 years explicit + fade
Forward Tilt (NTM/TTM)×1.03 (applied to P/E, EV/EBITDA, P/S)
Free Cash Flow (TTM)$-0.1B
Return on Equity (TTM)-31.9%
Book / Price322.2% — banking bias active (P/B is primary)
Debt / Equity0.00
Quality Score1/6 — cyclical/struggling (5y DCF)
SMA 50$4.27 (Market Anchor value)
SMA 20 / Bollinger Mid$4.26
Bollinger Width / SMA20199.6% (drives anchor stability)
Net Debt$-0.2B
Market Cap$0B
Peers used for multiples: ABT, PFE, REGN, TEVA (SIC-code peers; ETF co-membership was sector-incoherent)
Blended Fair Value
$34.74
Current Price
$4.50
Deviation
+50.0%
MethodImplied PriceWeightDetail
DCF n/a 0%
DDM (Gordon) n/a 0%
Peer P/E n/a 0% median 21.7× · 4 peers
Peer EV/EBITDA n/a 0% median 13.1× · 4 peers
Peer P/B $34.74 100% median 2.6× · 4 peers
Peer P/S n/a 0% median 2.9× · 4 peers
Market Anchor (SMA50) $4.27 0% stability 0% (BB-width)
Options Expected (B-L 30d) n/a 0%
As of 2026-06-26 · updated 2026-06-26 20:59:30.580000
Info
Industry (SIC)
PHARMACEUTICAL PREPARATIONS (2834)
Exchange
XNAS
Market Cap
$0.2B

OnKure Therapeutics Inc is a clinical-stage biopharmaceutical company focused on discovering and developing precision medicines that target biologically validated drivers of cancers underserved by available therapies. The company uses a structure-based drug design platform to develop a pipeline of drug candidates aimed at optimizing efficacy and tolerability. The company has multiple programs focused on targeting oncogenic PI3Kα. Its flagship program is OKI-219. The company operates in one operating segment: clinical research.

Chart
Seasonality
MonthAvg ReturnYears of Data
Jan -18.41% 2
Feb -7.28% 2
Mar +19.28% 2
Apr -4.91% 2
May -11.12% 2
Jun +0.62% 2
Jul -11.95% 1
Aug +1.10% 1
Sep +1.48% 1
Oct +9.31% 2
Nov -10.20% 2
Dec -20.99% 2
Technical Indicators

Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.

Trend Indicators
  • SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
  • EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
  • MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
  • ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
  • +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
  • RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
  • Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
  • Williams %R — inverted scale: <−80 oversold, >−20 overbought.

Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.

Volume & Volatility
  • Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
  • OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
  • Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
  • ATR / True Range — average daily $ move; sizing and stop-loss reference.
  • HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.

Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →

Trend Indicators
SMA 20: $4.28
SMA 50: $4.27
SMA 200: $3.37
Current: $4.50
EMA 12: $4.31
EMA 26: $4.23
MACD: 0.0713 | Signal: 0.0130
BULLISH
ADX (14): 14.41
RANGE
+DI: 14.55
−DI: 12.39
Momentum Oscillators
RSI (14): 58.23
NEUTRAL
Stoch %K: 60.85
Stoch %D: 52.84
Williams %R: -15.87
Volume & Volatility
BB Upper: $4.47
BB Lower: $4.08
OVERBOUGHT
OBV: 1,246,036
Vol SMA 20: 559,998
Vol ROC: 2107.60%
ATR: $0.37
True Range: $0.48
HV 20: 47.0%
HV 30: 65.0%
HV 60: 69.4%

Data Summary
Data Points: 431
Last Updated: 2026-06-26T21:15:13.585000
Date Range: 2024-10-07T00:00:00 – 2026-06-26T00:00:00
AI Analysis

Choose Frenzy-Fast™ for quick analysis or Frenzy-Pro™ for comprehensive analysis.

Analysis includes technical indicators, news sentiment, risk assessment, and specific price levels to watch.

News
Earnings History
1 of 1 under expected move
Each row pairs the pre-earnings straddle-implied expected move with the realized close-to-close move. Sorted oldest first.
Earnings Date Timing Expected Move Actual Move Ratio Outcome
2025-05-06 unknown 104.73% 3.15% 0.03x Within
Options Activity
IV Rank (30D)
0
IV Rank (7D)
0
Avg IV
0.0%
Straddle (30D)
$2.72
Straddle (7D)
$2.72
P/C Volume
1.00
Spread Scanner GPU

Each spread is ranked by a composite score built in three stages. Full documentation →

Stage 1 — Base Score (GPU scanner)

score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.

Stage 2 — Skew Adjustment (±25% cap)

RR and BF (30-delta) from the persisted per-symbol skew snapshot — wing strikes picked by real greeks.delta, not a moneyness proxy. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.

Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
  • RSI <40 bullish / >60 bearish
  • MACD crossover + histogram trend
  • Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
  • Stochastic %K <20 / >80
  • Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
  • Blended ATR + straddle expected-move penalty
  • Bollinger Band signal (+ counter-trend penalty)
  • BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
  • IV rank ≥ 75 → strong boost for credit spreads
  • IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
  • Min open interest across all legs
  • OI < 100 → −0.10 · OI < 500 → −0.05

score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →

Enter a ticker to scan for optimal spread opportunities.

Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.

Skew (Wing IV − ATM IV)
DTE:
Wing Δ:
Metric:
Wing vs ATM
IV(put wing) − IV(ATM), in vol points

How much the OTM put trades above (or below) the at-the-money strike. Measures the height of the put-side tail relative to ATM — i.e. how expensive crash insurance is on this name.

  • Positive (typical) — wing IV > ATM IV. Standard equity put skew: portfolios bid up crash protection, so OTM puts trade richer than ATM.
  • Near zero or negative (unusual) — wing IV ≤ ATM IV. Flat or inverted put side. Common when there's no fear demand, in tightly mean-reverting names, or right after an earnings catalyst clears.
  • Percentile vs own 3-yr history: high = wings rich (good time to sell wing premium); low = wings cheap (good time to buy protection).
  • Not directional — high or low wings don't predict up or down moves. It's a price tag on tail insurance, not a forecast.
Risk Reversal
IV(call wing) − IV(put wing), equal delta on each side

Which side of the smile is the market paying up for? Measures the tilt of the surface — call skew vs put skew at matched deltas.

  • Negative (typical) — puts richer than calls. Standard equity behavior: hedging demand makes puts carry a premium. Most large-caps sit in the −1 to −5 vol-point range.
  • Strongly negative (< −5 pts) — heavy downside hedging, elevated fear, or an upcoming catalyst (earnings, FDA, macro event). Worth flagging.
  • Positive — calls richer than puts. Unusual for equities; signals bullish momentum, short-squeeze positioning, or takeover/M&A speculation.
  • Near zero — symmetric surface. Market sees roughly equal up/down risk. Rare for large-caps; more common in commodities and FX.
Reading them together

Wing-vs-ATM tells you how expensive the tails are. Risk Reversal tells you which side is favored. Combined:

  • High wing percentile + deeply negative RR → strong put bid; stress or major event priced in. Owning protection costs a premium; selling put premium is dangerous.
  • Low wing percentile + near-zero RR → complacency; insurance cheap and balanced. Good environment to add cheap downside hedges.
  • Positive RR + elevated wings → call-side fear-of-missing-out; common in squeeze setups. Upside calls expensive, downside puts not bid.
14 DTE / 10d
pts EXTREME
ATM — / Wing —
30 DTE / 10d
pts EXTREME
ATM — / Wing —

Percentile is the rank of today's reading within ~3 years of this symbol's own history. High percentile = wings are rich relative to history; not a directional signal. Skew is read off the chain in real time, not from CBOE SKEW.

Volatility Surface

Enter a ticker to render the implied volatility surface.

Volatility Smile

Enter a ticker to render the implied volatility smile.

IV Rank (7 DTE)
IV Rank (30 DTE)
Straddle Price (30 DTE)
Beta Analysis
Beta (1Y vs SPY)
1.19
Correlation (SPY)
20.1%
0.04
Ann. Volatility
73.8%
SPY Volatility
12.5%

Above average volatility - stock moves with market amplification

Beta & Alpha Over Time
Institutional Ownership (13F)
Latest filings — 2026-03-31
Diluted shares outstanding: 13,557,616 (as of 2026-03-31)

Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.

  • Shares — long equity positions in this name, aggregated across share classes.
  • Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
  • % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
  • Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.

Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.

50 filers27,729,296 shares$113.50M value204.53% of float
# Filer Shares Value % of Total % of Float Period
1 RA CAPITAL MANAGEMENT, L.P. 3,998,333 $16.55M 14.58% 29.49% 2026-03-31
2 ACORN CAPITAL ADVISORS, LLC 2,839,674 $11.76M 10.36% 20.95% 2026-03-31
3 StepStone Group LP 2,660,612 $11.01M 9.70% 19.62% 2026-03-31
4 ADAR1 Capital Management, LLC 2,434,941 $10.08M 8.88% 17.96% 2026-03-31
5 Prosight Management, LP 2,154,381 $8.92M 7.86% 15.89% 2026-03-31
6 BVF INC/IL 1,978,972 $8.19M 7.22% 14.60% 2026-03-31
7 Vivo Capital, LLC 1,927,710 $7.98M 7.03% 14.22% 2026-03-31
8 Vestal Point Capital, LP 1,839,819 $7.62M 6.71% 13.57% 2026-03-31
9 Foresite Capital Management VI LLC 1,445,783 $5.99M 5.27% 10.66% 2026-03-31
10 ADAGE CAPITAL PARTNERS GP, L.L.C. 1,204,819 $4.99M 4.39% 8.89% 2026-03-31
11 Sio Capital Management, LLC 1,078,965 $4.47M 3.94% 7.96% 2026-03-31
12 NEA Management Company, LLC 478,548 $1.98M 1.75% 3.53% 2026-03-31
13 Rosalind Advisors, Inc. 443,763 $1.84M 1.62% 3.27% 2026-03-31
14 VANGUARD GROUP INC Custodian 626,593 $1.82M 1.60% 4.62% 2025-12-31
15 RENAISSANCE TECHNOLOGIES LLC 377,250 $1.56M 1.38% 2.78% 2026-03-31
16 Carlyle Group Inc. 269,895 $1.12M 0.98% 1.99% 2026-03-31
17 Affinity Asset Advisors, LLC 240,963 $997.59K 0.88% 1.78% 2026-03-31
18 DV Trading LLC 240,963 $997.59K 0.88% 1.78% 2026-03-31
19 Sofinnova Investments, Inc. 141,700 $586.64K 0.52% 1.05% 2026-03-31
20 KOTLER KEVIN 197,691 $573.30K 0.51% 1.46% 2025-12-31
21 Stonepine Capital Management, LLC 132,578 $548.87K 0.48% 0.98% 2026-03-31
22 Shay Capital LLC 132,219 $547.39K 0.48% 0.98% 2026-03-31
23 CANTOR FITZGERALD, L. P. 99,900 $413.59K 0.36% 0.74% 2026-03-31
24 GEODE CAPITAL MANAGEMENT, LLC Custodian 98,750 $408.85K 0.36% 0.73% 2026-03-31
25 Rangeley Capital, LLC 95,000 $393.30K 0.35% 0.70% 2026-03-31
# Filer Notional Value % of Total Period
# Filer Notional Value % of Total Period
Insider Activity
Latest: 2026-06-24
Form 4 filings — insider beneficial-ownership changes by officers, directors, and 10%+ holders. Filed within 2 business days of transaction.
Filed Reporter Role Action Shares Avg Price Net $ Link
2026-06-24 Nicholas A Saccomano President and CEO Sell (S) −86 $4.40 -$378 EDGAR
2026-06-24 Jason A. Leverone Chief Financial Officer Sell (S) −303 $4.40 -$1.3K EDGAR
2026-06-08 Andrew John Phillips Director Grant (A) +7,650 opt EDGAR
2026-06-08 Edward T Mathers Director Grant (A) +7,650 opt EDGAR
2026-06-08 Valerie Malyvanh Jansen Director Grant (A) +7,650 opt EDGAR
2026-06-08 R Michael Carruthers Director Grant (A) +7,650 opt EDGAR
2026-06-08 Liam Ratcliffe Director Grant (A) +1,275 opt EDGAR
2026-06-08 MICHAEL G GREY Director Grant (A) +7,650 opt EDGAR
2026-04-03 Nicholas A Saccomano President and CEO Grant (A) +330,000 opt EDGAR
2026-04-03 Dylan Hartley Chief Scientific Officer Grant (A) +110,000 opt EDGAR
2026-04-03 Samuel Agresta Chief Medical Officer Grant (A) +110,000 opt EDGAR
2026-04-03 Jason A. Leverone Chief Financial Officer Grant (A) +110,000 opt EDGAR
2026-04-01 Liam Ratcliffe Director Grant (A) +15,300 opt EDGAR
2026-03-24 Nicholas A Saccomano President and CEO Sell (S) −86 $4.16 -$357 EDGAR
2026-03-24 Jason A. Leverone Chief Financial Officer Sell (S) −301 $4.16 -$1.3K EDGAR
Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (described in filing footnote — typically 401(k), trust, inheritance) · W = will/inheritance. Only P / S codes carry directional signal.
Insider Holdings
8 insiders · @ $4.50
Officers, directors, and 10%+ owners ranked by current disclosed exposure (shares × today's price). Shares are direct + indirect (via trusts / LLCs / spouse). Excludes unvested RSU and option grants — those aren't beneficially owned until vest.
# Insider Role Shares Disclosed Exposure Lifetime OM Net Filings Last Filed
1 ACORN CAPITAL ADVISORS GP, LLC 10%+ Owner 2,839,674 $12.78M $7.77M 1 2025-05-19
2 Cormorant Private Healthcare Fund IV LP 10%+ Owner 1,813,439 $8.16M -$289.4K 1 2025-05-14
3 Braden Michael Leonard 447,815 $2.02M $0 1 2024-10-09
4 Isaac Manke Director 20,583 $92.6K $0 6 2026-01-02
5 Jason A. Leverone Chief Financial Officer 18,802 $84.6K -$14.2K 9 2026-06-24
6 Edward T Mathers Director 15,310 $68.9K $0 7 2026-06-08
7 Nicholas A Saccomano President and CEO 11,247 $50.6K -$4.0K 9 2026-06-24
8 R Michael Carruthers Director 4,939 $22.2K $0 3 2026-06-08
Lifetime OM Net = signed sum of open-market buys (P) and sells (S) over their career; excludes grants, tax withholdings, and dispositions to issuer. A large negative number is normal for long-tenured executives — they've sold compensation grants over many years.
Notice of Proposed Sale (Form 144)
Latest: 2023-08-28
Last 30d: 0 filings  ·  Last 90d: 0 filings

What is Form 144? A notice of intent to sell restricted or control stock under Rule 144. Affiliates (officers, directors, 10%+ owners) and holders of restricted shares must file Form 144 when planning to sell more than 5,000 shares or $50,000 in any 3-month rolling window.

How it relates to Form 4: Form 144 is filed before the trade (up to 90 days in advance); Form 4 is filed within 2 business days after the trade executes. Not every Form 144 results in a sale — the filer may cancel or delay. Look for the corresponding Form 4 on the Insider Activity card to confirm a sale actually happened.

10b5-1 plans: Trades made under a pre-scheduled Rule 10b5-1 plan are not discretionary — they execute automatically on dates set months earlier, regardless of news. High 10b5-1 percentages mean less per-filing signal value, though cumulative selling volume still matters.

"Notice value": Aggregate market value the filer wrote into the Form 144 — i.e. the size of the planned sale, not necessarily the executed dollars. Amendments (Form 144/A) and post-cancellation refilings can inflate this if you sum naively; the rollup above excludes filings with zero stated value.

Source & freshness: Parsed directly from EDGAR primary-doc XML. Daily refresh; new filings typically appear here the morning after they hit EDGAR.

Filed Filer Role Shares Notice Value Planned Sale Broker Plan Link
2023-08-28 Hall Ashley Officer 15,625 $98.1K 2023-08-28 ETRADE FINANCIAL CORPORATION EDGAR
2023-06-23 Novo Holdings A/S 10% Stockholder 100,000 $735.0K 2023-06-23 Morgan Stanley & Co. LLC EDGAR
Notice value is the aggregate market value the filer states they intend to sell — not a confirmed transaction. Compare to Insider Activity (Form 4) to see which planned sales actually executed.
ETF Holders
# ETF Provider Weight $ Exposure ETF AUM As Of
Fundamentals

Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.

Metrics
  • Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
  • Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
  • Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
  • Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
How to read the bars
  • Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
  • YoY growth — compare to the same quarter a year earlier to remove seasonality.
  • Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
  • Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.

TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.

P/B Ratio0.9
EV/EBITDA0.3
TTM Net Income$-0.1B
TTM EPS$-4.33
ROE-31.9%