Q32 Bio Inc. Common Stock(QTTB)

Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership.

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.

QTTB $13.09
Snapshot
$13.09
52-Week Range
$1.34 – $15.02
YTD
+280.52%
IV Rank (30D)
8.25
Straddle Price
$3.83
P/C Vol Ratio
167.58
Market Cap
$0.2B
Fair Value
MODEL: LONG

A blended fair-value estimate combining up to six valuation methods. Each method is weighted by how well it fits the company — DCF down-weights for unprofitable names; DDM only fires for steady dividend payers; comparables down-weight when peer multiples disagree.

  • DCF (quality-aware) — projects free cash flow with a horizon that scales to business quality. True compounders (quality 6/6) get 10 years explicit + 10 years fade before terminal; cyclical/struggling names (quality 0-1) get a 5-year terminal cliff. Quality is scored from ROE, gross margin, growth, FCF margin, debt load, and FCF consistency — the same factors that drive market premium for compounders.
  • Market-Implied Growth (in Model Inputs) — reverse-DCF that answers "what growth rate is the market pricing in?". Lets you sanity-check the deviation: if implied growth is plausible for the business, the model's bearish flag may be wrong; if implausible, the market may be over-extrapolating.
  • DDM (Gordon Growth Dividend Model) — values the stream of future dividends. Only used when trailing yield ≥ 0.5% and dividend payments are stable.
  • P/E, EV/EBITDA, P/B, P/S — applies the peer-group median multiple to this company's per-share metric. Peers come from the same set as the "Related symbols" card. Earnings/sales metrics are forward-tilted by the company's recent revenue growth (capped at 25%) so they're comparable to peers' growth-embedded multiples — mimics how analysts use NTM rather than TTM. Per-multiple weights are biased by company quality (e.g. P/B down-weighted for asset-light tech).
  • Market Anchor (SMA50) — the 50-day moving average, weighted by recent trading-range stability (tighter Bollinger bands → higher weight). Captures information fundamentals miss (forward consensus, sentiment, supply/demand) — but only when recent trading is steady enough that the market has converged on a view. During wild breakouts or breakdowns the anchor's weight collapses.
  • Options Expected (B-L 30d) — the risk-neutral expected stock price at 30-day options expiration, derived from the full implied-volatility surface via Breeden-Litzenberger (second derivative of call price wrt strike → implied PDF, then E[S_T]). Forward-looking, captures all options-implied information (smile, skew, term structure) in one number. Weighted by chain liquidity. SP500-only at present (pre-computed daily). Backtest evidence: adds modest alpha across most bucket × holding combos.
  • Blended value — weighted average. Confidence reflects how many methods fired and how tight peer dispersion is.
  • Deviation pill — green when blended FV ≥ 10% above current price (undervalued); red when ≥ 10% below; grey otherwise.
10-yr Treasury (rf)4.44%
Beta vs SPY0.64
Cost of Equity (CAPM)7.65% (VRP-adj)
WACC9.15%
Volatility Risk Premium+24.0pp (IV − HV30)
Effective Tax Rate21.0%
Rev. Growth (YoY, DCF input)+3.0%
DCF Horizon10 years explicit + fade
Forward Tilt (NTM/TTM)×1.03 (applied to P/E, EV/EBITDA, P/S)
Free Cash Flow (TTM)$-0.0B
Return on Equity (TTM)71.8%
Book / Price27.8%
Gross Margin (TTM)100.0%
FCF Margin (TTM)-51.0%
Debt / Equity0.04
Quality Score3/6 — normal (10y DCF)
SMA 50$9.25 (Market Anchor value)
SMA 20 / Bollinger Mid$12.65
Bollinger Width / SMA20174.2% (drives anchor stability)
Net Debt$-0.0B
Market Cap$0B
Peers used for multiples: AGIO, CLPT, LGND, MYGN, PGEN, RIGL, XNCR (filtered from 8 ETF-co-members; sector bias active)
Model Conviction
93%
20-Day Fair Value
$14.06
α +7.4% rank 86%
40-Day Fair Value
$15.19
α +16.0% rank 81%
60-Day Fair Value
$15.89
α +21.4% rank 80%
MethodImplied PriceWeightDetail
DCF n/a 0%
DDM (Gordon) n/a 0%
Peer P/E n/a 0%
Peer EV/EBITDA n/a 0%
Peer P/B $8.05 5% median 2.2× · 7 peers
Peer P/S $60.17 16% median 13.8× · 7 peers
Market Anchor (SMA50) $9.25 80% stability 76% (BB-width)
Options Expected (B-L 30d) n/a 0%
As of 2026-07-03 · updated 2026-07-03 20:15:30.722000
Info
Industry (SIC)
PHARMACEUTICAL PREPARATIONS (2834)
Exchange
XNAS
Market Cap
$0.2B

Q32 Bio Inc is a clinical-stage biotechnology company focused on developing novel biologics to restore healthy immune balance in patients with alopecia areata (AA) and other autoimmune and inflammatory diseases driven by immune dysfunction. Its product candidate, bempikibart (ADX 914), is a fully human anti-interleukin 7 receptor alpha (IL-7R) antagonist monoclonal antibody designed to block signaling mediated by interleukin 7 (IL 7) and thymic stromal lymphopoietin (TSLP) and re-regulate adaptive immune function. The company has completed two Phase 2a clinical trials evaluating bempikibart, S…

Chart
Seasonality
MonthAvg ReturnYears of Data
Jan +6.17% 2
Feb +1.55% 2
Mar +8.49% 3
Apr +10.06% 3
May +34.86% 3
Jun -13.22% 3
Jul +51.79% 3
Aug -0.72% 2
Sep +13.15% 2
Oct +29.39% 2
Nov -33.85% 2
Dec -55.20% 2
Technical Indicators

Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.

Trend Indicators
  • SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
  • EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
  • MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
  • ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
  • +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
  • RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
  • Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
  • Williams %R — inverted scale: <−80 oversold, >−20 overbought.

Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.

Volume & Volatility
  • Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
  • OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
  • Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
  • ATR / True Range — average daily $ move; sizing and stop-loss reference.
  • HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.

Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →

Trend Indicators
SMA 20: $12.65
SMA 50: $9.25
SMA 200: $5.17
Current: $13.09
EMA 12: $12.62
EMA 26: $11.68
MACD: 0.9435 | Signal: -0.1680
BULLISH
ADX (14): 32.94
TREND
+DI: 26.27
−DI: 15.10
Momentum Oscillators
RSI (14): 57.89
NEUTRAL
Stoch %K: 50.71
Stoch %D: 59.25
Williams %R: -43.18
Volume & Volatility
BB Upper: $14.05
BB Lower: $11.26
NEUTRAL
OBV: 241,507,954
Vol SMA 20: 473,704
Vol ROC: -35.32%
ATR: $1.39
True Range: $0.76
HV 20: 107.7%
HV 30: 215.5%
HV 60: 168.5%

Data Summary
Data Points: 500
Last Updated: 2026-07-02T21:15:12.536000
Date Range: 2024-07-05T00:00:00 – 2026-07-02T00:00:00
AI Analysis

Choose Frenzy-Fast™ for quick analysis or Frenzy-Pro™ for comprehensive analysis.

Analysis includes technical indicators, news sentiment, risk assessment, and specific price levels to watch.

News
Earnings History
5 of 5 under expected move
Each row pairs the pre-earnings straddle-implied expected move with the realized close-to-close move. Sorted oldest first.
Earnings Date Timing Expected Move Actual Move Ratio Outcome
2024-08-08 After-Close 19.11% 7.39% 0.39x Within
2024-11-07 After-Close 17.80% 4.57% 0.26x Within
2025-03-11 After-Close 33.93% 0.03% 0.00x Within
2025-05-08 After-Close 97.40% 0.65% 0.01x Within
2025-08-06 After-Close 53.85% 8.21% 0.15x Within
Options Activity
IV Rank (30D)
8.25
IV Rank (7D)
8.25
Avg IV
239.5%
Straddle (30D)
$3.83
Straddle (7D)
$3.83
P/C Volume
167.58
Spread Scanner GPU

Each spread is ranked by a composite score built in three stages. Full documentation →

Stage 1 — Base Score (GPU scanner)

score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.

Stage 2 — Skew Adjustment (±25% cap)

RR and BF (30-delta) from the persisted per-symbol skew snapshot — wing strikes picked by real greeks.delta, not a moneyness proxy. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.

Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
  • RSI <40 bullish / >60 bearish
  • MACD crossover + histogram trend
  • Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
  • Stochastic %K <20 / >80
  • Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
  • Blended ATR + straddle expected-move penalty
  • Bollinger Band signal (+ counter-trend penalty)
  • BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
  • IV rank ≥ 75 → strong boost for credit spreads
  • IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
  • Min open interest across all legs
  • OI < 100 → −0.10 · OI < 500 → −0.05

score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →

Enter a ticker to scan for optimal spread opportunities.

Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.

Skew (Wing IV − ATM IV)
DTE:
Wing Δ:
Metric:
Wing vs ATM
IV(put wing) − IV(ATM), in vol points

How much the OTM put trades above (or below) the at-the-money strike. Measures the height of the put-side tail relative to ATM — i.e. how expensive crash insurance is on this name.

  • Positive (typical) — wing IV > ATM IV. Standard equity put skew: portfolios bid up crash protection, so OTM puts trade richer than ATM.
  • Near zero or negative (unusual) — wing IV ≤ ATM IV. Flat or inverted put side. Common when there's no fear demand, in tightly mean-reverting names, or right after an earnings catalyst clears.
  • Percentile vs own 3-yr history: high = wings rich (good time to sell wing premium); low = wings cheap (good time to buy protection).
  • Not directional — high or low wings don't predict up or down moves. It's a price tag on tail insurance, not a forecast.
Risk Reversal
IV(call wing) − IV(put wing), equal delta on each side

Which side of the smile is the market paying up for? Measures the tilt of the surface — call skew vs put skew at matched deltas.

  • Negative (typical) — puts richer than calls. Standard equity behavior: hedging demand makes puts carry a premium. Most large-caps sit in the −1 to −5 vol-point range.
  • Strongly negative (< −5 pts) — heavy downside hedging, elevated fear, or an upcoming catalyst (earnings, FDA, macro event). Worth flagging.
  • Positive — calls richer than puts. Unusual for equities; signals bullish momentum, short-squeeze positioning, or takeover/M&A speculation.
  • Near zero — symmetric surface. Market sees roughly equal up/down risk. Rare for large-caps; more common in commodities and FX.
Reading them together

Wing-vs-ATM tells you how expensive the tails are. Risk Reversal tells you which side is favored. Combined:

  • High wing percentile + deeply negative RR → strong put bid; stress or major event priced in. Owning protection costs a premium; selling put premium is dangerous.
  • Low wing percentile + near-zero RR → complacency; insurance cheap and balanced. Good environment to add cheap downside hedges.
  • Positive RR + elevated wings → call-side fear-of-missing-out; common in squeeze setups. Upside calls expensive, downside puts not bid.
14 DTE / 10d
pts EXTREME
ATM — / Wing —
30 DTE / 10d
pts EXTREME
ATM — / Wing —

Percentile is the rank of today's reading within ~3 years of this symbol's own history. High percentile = wings are rich relative to history; not a directional signal. Skew is read off the chain in real time, not from CBOE SKEW.

Volatility Surface

Enter a ticker to render the implied volatility surface.

Volatility Smile

Enter a ticker to render the implied volatility smile.

IV Rank (7 DTE)
IV Rank (30 DTE)
Straddle Price (30 DTE)
Beta Analysis
Beta (1Y vs SPY)
0.52
Correlation (SPY)
3.3%
0.00
Ann. Volatility
196.3%
SPY Volatility
12.6%

Low volatility - stock moves less than market

Beta & Alpha Over Time
Institutional Ownership (13F)
Latest filings — 2026-03-31
Diluted shares outstanding: 12,712,081 (as of 2026-03-31)

Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.

  • Shares — long equity positions in this name, aggregated across share classes.
  • Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
  • % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
  • Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.

Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.

53 filers8,346,197 shares$50.66M value65.66% of float
# Filer Shares Value % of Total % of Float Period
1 ORBIMED ADVISORS LLC 2,252,987 $14.46M 28.55% 17.72% 2026-03-31
2 Atlas Venture Life Science Advisors, LLC 2,092,106 $13.43M 26.51% 16.46% 2026-03-31
3 Carlyle Group Inc. 1,102,741 $7.08M 13.98% 8.67% 2026-03-31
4 ARCH Venture Management, LLC 320,482 $2.06M 4.06% 2.52% 2026-03-31
5 ACORN CAPITAL ADVISORS, LLC 315,052 $2.02M 3.99% 2.48% 2026-03-31
6 MACKENZIE FINANCIAL CORP 246,304 $1.58M 3.12% 1.94% 2026-03-31
7 Sanofi 244,083 $1.57M 3.09% 1.92% 2026-03-31
8 RENAISSANCE TECHNOLOGIES LLC 206,915 $1.33M 2.62% 1.63% 2026-03-31
9 VANGUARD GROUP INC Custodian 321,051 $1.07M 2.10% 2.53% 2025-12-31
10 MONIMUS CAPITAL MANAGEMENT, LP 134,310 $862.27K 1.70% 1.06% 2026-03-31
11 GEODE CAPITAL MANAGEMENT, LLC Custodian 118,152 $758.74K 1.50% 0.93% 2026-03-31
12 PFIZER INC 101,618 $736.73K 1.45% 0.80% 2026-03-31
13 Opaleye Management Inc. 213,363 $708.37K 1.40% 1.68% 2025-12-31
14 BlackRock, Inc. Custodian 86,147 $553.06K 1.09% 0.68% 2026-03-31
15 JANE STREET GROUP, LLC Custodian 65,599 $421.14K 0.83% 0.52% 2026-03-31
16 MARSHALL WACE, LLP Custodian 52,440 $336.66K 0.66% 0.41% 2026-03-31
17 TWO SIGMA INVESTMENTS, LP 42,346 $271.86K 0.54% 0.33% 2026-03-31
18 STATE STREET CORP 41,514 $266.52K 0.53% 0.33% 2026-03-31
19 ADAR1 Capital Management, LLC 35,000 $224.70K 0.44% 0.28% 2026-03-31
20 Affinity Asset Advisors, LLC 27,777 $178.33K 0.35% 0.22% 2026-03-31
21 NORTHERN TRUST CORP Custodian 25,033 $160.71K 0.32% 0.20% 2026-03-31
22 Cetera Investment Advisers 20,695 $132.86K 0.26% 0.16% 2026-03-31
23 AMERICAN CENTURY COMPANIES INC 18,770 $120.50K 0.24% 0.15% 2026-03-31
24 CITADEL ADVISORS LLC Custodian 15,481 $99.39K 0.20% 0.12% 2026-03-31
25 BRIDGEWAY CAPITAL MANAGEMENT, LLC 12,613 $80.97K 0.16% 0.10% 2026-03-31
# Filer Notional Value % of Total Period
# Filer Notional Value % of Total Period
Insider Activity
Latest: 2026-06-16
Form 4 filings — insider beneficial-ownership changes by officers, directors, and 10%+ holders. Filed within 2 business days of transaction.
Filed Reporter Role Action Shares Avg Price Net $ Link
2026-06-16 KATHLEEN LAPORTE Director Grant (A) +9,810 opt EDGAR
2026-06-16 Mark T Iwicki Director Grant (A) +9,810 opt EDGAR
2026-06-16 DAVID S. GRAYZEL Director Grant (A) +9,810 opt EDGAR
2026-06-16 Mary Thistle Director Grant (A) +9,810 opt EDGAR
2026-06-16 ARTHUR TZIANABOS Director Grant (A) +9,810 opt EDGAR
2026-06-16 Isaac Manke Director Grant (A) +9,810 opt EDGAR
2026-06-16 Diyong Xu Director Grant (A) +9,810 opt EDGAR
2026-06-16 Sven Ante Lundberg Director Grant (A) +9,810 opt EDGAR
2026-06-01 OrbiMed Genesis GP LLC Director Buy (P) +5,625,000 $8.00 $45.00M EDGAR
2026-06-01 Diyong Xu Director Buy (P) +1,875,000 $8.00 $15.00M EDGAR
2026-03-20 Jodie Pope Morrison CEO Award (A) +132,000 EDGAR
2026-03-20 Lee Kalowski CFO and President Award (A) +53,250 EDGAR
2026-03-20 Shelia M. Violette Chief Scientific Officer Award (A) +37,500 EDGAR
2026-02-27 Jodie Pope Morrison CEO Sell (S) −9,896 $4.51 -$44.7K EDGAR
2026-02-27 Lee Kalowski CFO and President Sell (S) −3,995 $4.51 -$18.0K EDGAR
Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (described in filing footnote — typically 401(k), trust, inheritance) · W = will/inheritance. Only P / S codes carry directional signal.
Insider Holdings
9 insiders · @ $13.09
Officers, directors, and 10%+ owners ranked by current disclosed exposure (shares × today's price). Shares are direct + indirect (via trusts / LLCs / spouse). Excludes unvested RSU and option grants — those aren't beneficially owned until vest.
# Insider Role Shares Disclosed Exposure Lifetime OM Net Filings Last Filed
1 OrbiMed Genesis GP LLC Director 625,000 $8.18M $45.00M 1 2026-06-01
2 Diyong Xu Director 625,000 $8.18M $15.00M 5 2026-06-16
3 Jodie Pope Morrison CEO 221,104 $2.89M -$141.4K 6 2026-03-20
4 Shelia M. Violette Chief Scientific Officer 129,346 $1.69M -$18.1K 7 2026-03-20
5 Lee Kalowski CFO and President 89,193 $1.17M -$57.1K 6 2026-03-20
6 Jason Campagna Chief Medical Officer 37,500 $490.9K $0 2 2025-02-26
7 ARTHUR TZIANABOS Director 7,983 $104.5K -$6.4K 5 2026-06-16
8 Paul Alloway See Remarks 2,596 $34.0K -$6.5K 2 2024-04-23
9 Charles Jr Michaud See Remarks 927 $12.1K -$1.8K 2 2024-04-23
Lifetime OM Net = signed sum of open-market buys (P) and sells (S) over their career; excludes grants, tax withholdings, and dispositions to issuer. A large negative number is normal for long-tenured executives — they've sold compensation grants over many years.
Notice of Proposed Sale (Form 144)
Latest: 2025-12-02
Last 30d: 0 filings  ·  Last 90d: 0 filings

What is Form 144? A notice of intent to sell restricted or control stock under Rule 144. Affiliates (officers, directors, 10%+ owners) and holders of restricted shares must file Form 144 when planning to sell more than 5,000 shares or $50,000 in any 3-month rolling window.

How it relates to Form 4: Form 144 is filed before the trade (up to 90 days in advance); Form 4 is filed within 2 business days after the trade executes. Not every Form 144 results in a sale — the filer may cancel or delay. Look for the corresponding Form 4 on the Insider Activity card to confirm a sale actually happened.

10b5-1 plans: Trades made under a pre-scheduled Rule 10b5-1 plan are not discretionary — they execute automatically on dates set months earlier, regardless of news. High 10b5-1 percentages mean less per-filing signal value, though cumulative selling volume still matters.

"Notice value": Aggregate market value the filer wrote into the Form 144 — i.e. the size of the planned sale, not necessarily the executed dollars. Amendments (Form 144/A) and post-cancellation refilings can inflate this if you sum naively; the rollup above excludes filings with zero stated value.

Source & freshness: Parsed directly from EDGAR primary-doc XML. Daily refresh; new filings typically appear here the morning after they hit EDGAR.

Filed Filer Role Shares Notice Value Planned Sale Broker Plan Link
2025-12-02 JODIE MORRISON Officer, Director 22,506 $77.9K 2025-12-02 Morgan Stanley Smith Barney LLC … EDGAR
2025-12-02 LEE KALOWSKI Officer 9,072 $31.4K 2025-12-02 Morgan Stanley Smith Barney LLC … EDGAR
Notice value is the aggregate market value the filer states they intend to sell — not a confirmed transaction. Compare to Insider Activity (Form 4) to see which planned sales actually executed.
ETF Holders
# ETF Provider Weight $ Exposure ETF AUM As Of
Fundamentals

Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.

Metrics
  • Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
  • Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
  • Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
  • Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
How to read the bars
  • Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
  • YoY growth — compare to the same quarter a year earlier to remove seasonality.
  • Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
  • Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.

TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.

P/E Ratio4.7
P/B Ratio4.6
P/S Ratio4.0
EV/EBITDA7.9
TTM Revenue$0.1B
TTM Net Income$0.0B
TTM EPS$2.79
ROE71.8%
Debt/Equity0.18