BIOS Capital Management, LP — 13F Holdings & Portfolio
CIK 1813845 · latest 13F-HR filed 2026-05-13
BIOS Capital Management, LP manages $52.9M in 13F-reported U.S. long-equity assets across 10 reported positions as of its 2026-03-31 13F-HR filing. Its largest disclosed positions are ACTU (44.54%), IRD (31.70%), CGTX (7.91%). Quarter over quarter (versus its 2025-12-31 filing) the fund opened 0 new positions, exited 0, added to 2, and trimmed 4.
AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.
$52.9M
Long-equity book
10
Distinct positions
2026-03-31
Filed 2026-05-13
+0 / −0 / ↑2 / ↓4
vs 2025-12-31
| Name | Title / Status | Ownership | Type |
|---|
Top Adds (vs prior quarter)
- OPUS GENETICS INC$9.4M +126.4%
- REIN THERAPEUTICS INC$615.8K +31.4%
Top Trims
- ACTUATE THERAPEUTICS INC-$34.0M -55.2%
- COGNITION THERAPEUTICS INC-$3.5M -43.7%
- LANTERN PHARMA INC-$1.9M -61.3%
- IN8BIO INC-$344.6K -58.1%
Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).
| # | Issuer | Symbol | CUSIP | Value | Weight | Shares | Type |
|---|---|---|---|---|---|---|---|
| 1 | ACTUATE THERAPEUTICS INC | ACTU | 005083100 | $23.5M | 44.54% | 8,594,141 | SH |
| 2 | OPUS GENETICS INC | IRD | 67577R102 | $16.8M | 31.70% | 3,683,429 | SH |
| 3 | COGNITION THERAPEUTICS INC | CGTX | 19243B102 | $4.2M | 7.91% | 5,499,905 | SH |
| 4 | ACTUATE THERAPEUTICS INC | ACTU | 005083100 | $4.0M | 7.55% | 1,455,855 | SH |
| 5 | REIN THERAPEUTICS INC | RNTX | 00887A204 | $2.3M | 4.32% | 1,758,375 | SH |
| 6 | LANTERN PHARMA INC | LTRN | 51654W101 | $1.2M | 2.24% | 864,435 | SH |
| 7 | COGNITION THERAPEUTICS INC | CGTX | 19243B102 | $380.1K | 0.72% | 500,095 | SH |
| 8 | REIN THERAPEUTICS INC | RNTX | 00887A204 | $291.2K | 0.55% | 224,000 | SH |
| 9 | IN8BIO INC | INAB | 45674E208 | $128.5K | 0.24% | 86,848 | SH |
| 10 | IN8BIO INC | INAB | 45674E208 | $119.8K | 0.23% | 80,957 | SH |
| Period | Filed | AUM | Holdings | Accession |
|---|---|---|---|---|
| 2026-03-31 | 2026-05-13 | $52.9M | 10 | 0001813845-26-000003 |
| 2025-12-31 | 2026-02-13 | $82.6M | 9 | 0001813845-26-000002 |
| 2025-09-30 | 2025-11-12 | $88.9M | 9 | 0001104659-25-110482 |