Knott David M Jr — 13F Holdings & Portfolio
CIK 1892770 · latest 13F-HR filed 2026-08-12
Knott David M Jr manages $189.2M in 13F-reported U.S. long-equity assets across 86 reported positions as of its 2026-06-30 13F-HR filing. Its largest disclosed positions are GOOG (17.03%), APO (14.07%), SNDX (5.05%). Quarter over quarter (versus its 2026-03-31 filing) the fund opened 11 new positions, exited 12, added to 40, and trimmed 16.
AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.
485 UNDERHILL BOULEVARD, SUITE 205
SYOSSET, NY 11791
$189.2M
Long-equity book
86
Distinct positions
2026-06-30
Filed 2026-08-12
+11 / −12 / ↑40 / ↓16
vs 2026-03-31
| Name | Title / Status | Ownership | Type |
|---|
Top Adds (vs prior quarter)
- Alphabet Inc-Cl C$6.1M +23.2%
- Travere Therapeutics, Inc.$4.2M +100.3%
- Xeris Biopharma Holdings, Inc.$2.2M +36.6%
- Alkermes PLC$2.1M +50.3%
- Apollo Global Management, Inc.$1.6M +6.2%
Top Trims
- Bristol-Myers Squibb Company-$710.9K -86.1%
- LPL Financial Holdings Inc.-$316.0K -6.4%
- DocGo, Inc.-$301.8K -18.0%
- Viridian Therapeutics, Inc.-$215.4K -6.1%
- Canadian Natural Resources Limited-$155.1K -18.9%
New Positions
- Catalyst Pharmaceuticals, Inc.$3.6M
- Spruce Biosciences, Inc.$1.1M
- DuPont de Nemours, Inc.$511.0K
- Insmed Incorporated$453.5K
- LB Pharmaceuticals, Inc.$420.8K
Exited Positions
- Catalyst Pharmaceuticals, Inc.$3.0M
- Arcellx Inc$2.2M
- Cytokinetics, Incorporated$1.6M
- Centessa Pharmaceuticals PLC$1.5M
- ADMA Biologics, Inc.$542.4K
Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).
| # | Issuer | Symbol | CUSIP | Value | Weight | Shares | Type |
|---|---|---|---|---|---|---|---|
| 1 | Alphabet Inc-Cl C | GOOG | 02079K107 | $32.2M | 17.03% | 91,200 | SH |
| 2 | Apollo Global Management, Inc. | APO | 03769M106 | $26.6M | 14.07% | 225,000 | SH |
| 3 | Syndax Pharmaceutical, Inc. | SNDX | 87164F105 | $9.6M | 5.05% | 437,245 | SH |
| 4 | Xeris Biopharma Holdings, Inc. | XERS | 98422E103 | $8.4M | 4.44% | 1,060,000 | SH |
| 5 | Travere Therapeutics, Inc. | TVTX | 89422G107 | $8.4M | 4.42% | 147,282 | SH |
| 6 | Protagonist Therapeutics, Inc | PTGX | 74366E102 | $7.7M | 4.08% | 63,000 | SH |
| 7 | Bridgebio Pharma, Inc. | BBIO | 10806X102 | $6.9M | 3.66% | 92,850 | SH |
| 8 | Iovance Biotherapeutics, Inc. | IOVA | 462260100 | $6.7M | 3.52% | 1,600,000 | SH |
| 9 | Alkermes PLC | ALKS | G01767105 | $6.4M | 3.37% | 121,759 | SH |
| 10 | JPMorgan Chase & Co. | JPM | 46625H100 | $5.9M | 3.13% | 18,098 | SH |
| 11 | Janus Henderson AAA CLO ETF | JAAA | 47103U845 | $4.7M | 2.50% | 93,528 | SH |
| 12 | LPL Financial Holdings Inc. | LPLA | 52012V100 | $4.6M | 2.46% | 16,500 | SH |
| 13 | Cogent Biosciences Inc. | COGT | 19240Q201 | $4.3M | 2.27% | 111,081 | SH |
| 14 | TG Therapeutics, Inc. | TGTX | 88322Q108 | $3.7M | 1.94% | 66,839 | SH |
| 15 | Catalyst Pharmaceuticals, Inc. | CLST | 14888L101 | $3.6M | 1.89% | 114,000 | SH |
| 16 | Agios Pharmaceutical, Inc. | AGIO | 00847X104 | $3.5M | 1.86% | 95,058 | SH |
| 17 | Viridian Therapeutics, Inc. | VRDN | 92790C104 | $3.3M | 1.76% | 181,000 | SH |
| 18 | Relmada Therapeutics, Inc. | RLMD | 75955J402 | $3.1M | 1.65% | 451,000 | SH |
| 19 | Arcus Biosciences, Inc. | RCUS | 03969F109 | $2.5M | 1.32% | 81,241 | SH |
| 20 | Cybin Inc | HELP | 23256X407 | $2.4M | 1.29% | 370,000 | SH |
| 21 | SPDR S&P Biotech ETF | XBI | 78464A870 | $2.4M | 1.25% | 15,000 | SH |
| 22 | Rezolute, Inc. | RZLT | 76200L309 | $1.9M | 1.02% | 370,000 | SH |
| 23 | AllianceBernstein Holding L.P. | AB | 01881G106 | $1.7M | 0.89% | 48,000 | SH |
| 24 | Madrigal Pharmaaceuticals, Inc. | MDGL | 558868105 | $1.6M | 0.85% | 3,000 | SH |
| 25 | AtriCure, Inc. | ATRC | 04963C209 | $1.4M | 0.76% | 51,400 | SH |
| 26 | DocGo, Inc. | DCGO | 256086109 | $1.4M | 0.73% | 2,670,850 | SH |
| 27 | Ardelyx, Inc. | ARDX | 039697107 | $1.3M | 0.71% | 263,168 | SH |
| 28 | Ultragenyx Pharmaceutical Inc. | RARE | 90400D108 | $1.3M | 0.67% | 38,069 | SH |
| 29 | The Panagram BBB-B CLO ETF | CLOZ | 81752T528 | $1.3M | 0.67% | 47,807 | SH |
| 30 | Cullinan Therapeutics, Inc. | CGEM | 230031106 | $1.3M | 0.67% | 69,182 | SH |
| 31 | Vera Therapeutics, Inc. | VERA | 92337R101 | $1.1M | 0.59% | 26,000 | SH |
| 32 | Orchestra Biomed Holdings, Inc. | OBIO | 68572M106 | $1.1M | 0.58% | 253,651 | SH |
| 33 | Spruce Biosciences, Inc. | SPRB | 85209E208 | $1.1M | 0.57% | 20,000 | SH |
| 34 | Connect Biopharma Holdings Limited | CNTB | G23549101 | $1.1M | 0.56% | 444,862 | SH |
| 35 | iShares Biotechnology ETF | IBB | 464287556 | $1.0M | 0.55% | 5,500 | SH |
| 36 | Johnson & Johnson | JNJ | 478160104 | $1.0M | 0.54% | 4,000 | SH |
| 37 | Biogen Inc. | BIIB | 09062X103 | $864.2K | 0.46% | 4,000 | SH |
| 38 | Pfizer Inc. | PFE | 717081103 | $778.7K | 0.41% | 32,337 | SH |
| 39 | Apple Inc. | AAPL | 037833100 | $721.7K | 0.38% | 2,494 | SH |
| 40 | Canadian Natural Resources Limited | CNQ | 136385101 | $663.6K | 0.35% | 16,800 | SH |
| 41 | Pelthos Therapeutics, Inc. | PTHS | 171126204 | $623.8K | 0.33% | 22,073 | SH |
| 42 | International Business Machines | IBM | 459200101 | $602.4K | 0.32% | 2,142 | SH |
| 43 | Microsoft Corporation | MSFT | 594918104 | $596.8K | 0.32% | 1,600 | SH |
| 44 | Verastem Inc. | VSTM | 92337C203 | $592.1K | 0.31% | 155,000 | SH |
| 45 | Kura Oncology, Inc. | KURA | 50127T109 | $578.9K | 0.31% | 52,767 | SH |
| 46 | Solid Bioscience Inc. | SLDB | 83422E204 | $561.5K | 0.30% | 56,208 | SH |
| 47 | DuPont de Nemours, Inc. | DD | 36614N201 | $511.0K | 0.27% | 3,767 | SH |
| 48 | Insmed Incorporated | INSM | 457669307 | $453.5K | 0.24% | 4,253 | SH |
| 49 | LB Pharmaceuticals, Inc. | LBRX | 50180M108 | $420.8K | 0.22% | 12,965 | SH |
| 50 | CareDx, Inc. | CDNA | 14167L103 | $388.5K | 0.21% | 13,630 | SH |
| Period | Filed | AUM | Holdings | Accession |
|---|---|---|---|---|
| 2026-06-30 | 2026-08-12 | $189.2M | 86 | 0001104659-26-094536 |
| 2026-03-31 | 2026-05-14 | $168.0M | 88 | 0001104659-26-060750 |
| 2025-12-31 | 2026-02-12 | $215.9M | 91 | 0001104659-26-014058 |
| 2025-09-30 | 2025-11-12 | $248.0M | 92 | 0001104659-25-110124 |