Xeris Biopharma Holdings, Inc. Common Stock (XERS) Stock Quote & Options Analysis | Frenzy Capital

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Snapshot
$6.16
52-Week Range
$4.30 – $10.08
YTD
-16.15%
IV Rank (30D)
21.53
Straddle Price
$1.65
P/C Vol Ratio
0.18
Market Cap
$1.1B
Info
Industry (SIC)
PHARMACEUTICAL PREPARATIONS (2834)
Exchange
XNAS
Market Cap
$1.1B

Xeris Biopharma Holdings Inc is a commercial-stage biopharmaceutical company focused on developing and commercializing therapies for people with chronic endocrine and neurological diseases in the United States. It offers Recorlev for the treatment of endogenous hypercortisolemia in patients with Cushing's syndrome; Gvoke for the treatment of severe hypoglycemia; and Keveyis for the treatment of Primary Periodic Paralysis (PPP). Additionally, the company is advancing its Phase 3-ready pipeline product, XP-8121, a once-weekly subcutaneous injection of levothyroxine, which leverages its proprieta…

Price History
Seasonality
MonthAvg ReturnYears of Data
Jan -3.47% 6
Feb +3.99% 6
Mar +4.17% 6
Apr -2.34% 6
May +7.23% 6
Jun -1.32% 5
Jul +0.93% 5
Aug +7.22% 5
Sep -7.01% 5
Oct -0.89% 5
Nov -5.32% 5
Dec +13.56% 5
Technical Indicators

Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.

Trend Indicators
  • SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
  • EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
  • MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
  • ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
  • +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
  • RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
  • Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
  • Williams %R — inverted scale: <−80 oversold, >−20 overbought.

Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.

Volume & Volatility
  • Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
  • OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
  • Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
  • ATR / True Range — average daily $ move; sizing and stop-loss reference.
  • HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.

Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →

Trend Indicators
SMA 20: $6.24
SMA 50: $5.98
SMA 200: $7.14
Current: $6.17
EMA 12: $6.22
EMA 26: $6.19
MACD: 0.0338 | Signal: -0.0226
BULLISH
ADX (14): 21.48
WEAK TREND
+DI: 25.66
−DI: 16.05
Momentum Oscillators
RSI (14): 49.50
NEUTRAL
Stoch %K: 36.45
Stoch %D: 27.10
Williams %R: -71.49
Volume & Volatility
BB Upper: $6.59
BB Lower: $5.90
NEUTRAL
OBV: 94,040,276
Vol SMA 20: 1,697,540
Vol ROC: -74.00%
ATR: $0.28
True Range: $0.31
HV 20: 45.1%
HV 30: 44.9%
HV 60: 49.3%

Data Summary
Data Points: 500
Last Updated: 2026-05-22T19:45:21.156000
Date Range: 2024-05-23T00:00:00 – 2026-05-21T00:00:00
AI Analysis

Choose Frenzy-Fast™ for quick analysis or Frenzy-Pro™ for comprehensive analysis.

Analysis includes technical indicators, news sentiment, risk assessment, and specific price levels to watch.

News
Options Activity
IV Rank (30D)
21.53
IV Rank (7D)
21.53
Avg IV
114.8%
Straddle (30D)
$1.65
Straddle (7D)
$1.65
P/C Volume
0.18
Spread Scanner GPU

Each spread is ranked by a composite score built in three stages. Full documentation →

Stage 1 — Base Score (GPU scanner)

score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.

Stage 2 — Skew Adjustment (±25% cap)

RR25 and BF25 from the live options chain. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.

Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
  • RSI <40 bullish / >60 bearish
  • MACD crossover + histogram trend
  • Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
  • Stochastic %K <20 / >80
  • Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
  • Blended ATR + straddle expected-move penalty
  • Bollinger Band signal (+ counter-trend penalty)
  • BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
  • IV rank ≥ 75 → strong boost for credit spreads
  • IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
  • Min open interest across all legs
  • OI < 100 → −0.10 · OI < 500 → −0.05

score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →

Enter a ticker to scan for optimal spread opportunities.

Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.

Volatility Surface

Enter a ticker to render the implied volatility surface.

IV Rank (7 DTE)
IV Rank (30 DTE)
Straddle Price (30 DTE)
Beta Analysis
Beta (1Y vs SPY)
1.00
Correlation (SPY)
21.3%
0.05
Ann. Volatility
56.5%
SPY Volatility
12.1%

Moderate volatility - stock generally follows market

Beta & Alpha Over Time
Institutional Ownership (13F)
Latest filings — 2026-03-31
Diluted shares outstanding: 171,862,648 (as of 2026-03-31)

Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.

  • Shares — long equity positions in this name, aggregated across share classes.
  • Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
  • % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
  • Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.

Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.

241 filers149,556,721 shares$755.97M value87.02% of float
# Filer Shares Value % of Total % of Float Period
1 VANGUARD GROUP INC Custodian 11,186,677 $87.82M 11.62% 6.51% 2025-12-31
2 BlackRock, Inc. Custodian 12,945,785 $75.09M 9.93% 7.53% 2026-03-31
3 CAPSTONE INVESTMENT ADVISORS, LLC 23,074,000 $47.18M 6.24% 13.43% 2026-03-31
4 D. E. Shaw & Co., Inc. Custodian 7,788,811 $45.18M 5.98% 4.53% 2026-03-31
5 VANGUARD CAPITAL MANAGEMENT LLC 6,980,882 $40.49M 5.36% 4.06% 2026-03-31
6 STATE STREET CORP 4,658,174 $27.02M 3.57% 2.71% 2026-03-31
7 GEODE CAPITAL MANAGEMENT, LLC Custodian 4,290,629 $24.89M 3.29% 2.50% 2026-03-31
8 Qube Research & Technologies Ltd 4,114,425 $23.86M 3.16% 2.39% 2026-03-31
9 Polar Asset Management Partners Inc. 10,500,000 $21.49M 2.84% 6.11% 2026-03-31
10 Rosalind Advisors, Inc. 3,231,700 $18.74M 2.48% 1.88% 2026-03-31
11 Nuveen, LLC Custodian 2,916,598 $16.92M 2.24% 1.70% 2026-03-31
12 VANGUARD PORTFOLIO MANAGEMENT LLC 2,665,608 $15.46M 2.05% 1.55% 2026-03-31
13 MORGAN STANLEY Custodian 2,572,654 $14.92M 1.97% 1.50% 2026-03-31
14 MILLENNIUM MANAGEMENT LLC Custodian 2,265,974 $13.14M 1.74% 1.32% 2026-03-31
15 WELLINGTON MANAGEMENT GROUP LLP Custodian 2,171,354 $12.59M 1.67% 1.26% 2026-03-31
16 TWO SIGMA INVESTMENTS, LP 1,924,202 $11.16M 1.48% 1.12% 2026-03-31
17 ARMISTICE CAPITAL, LLC 1,909,838 $11.08M 1.47% 1.11% 2026-03-31
18 Legal & General Group Plc Custodian 1,908,289 $11.07M 1.46% 1.11% 2026-03-31
19 Parkman Healthcare Partners LLC 1,721,264 $9.98M 1.32% 1.00% 2026-03-31
20 UBS Group AG Custodian 1,646,378 $9.55M 1.26% 0.96% 2026-03-31
21 GOLDMAN SACHS GROUP INC Custodian 1,613,650 $9.36M 1.24% 0.94% 2026-03-31
22 NORTHERN TRUST CORP Custodian 1,444,617 $8.38M 1.11% 0.84% 2026-03-31
23 AQR CAPITAL MANAGEMENT LLC Custodian 1,394,376 $8.09M 1.07% 0.81% 2026-03-31
24 Voss Capital, LP 1,386,927 $8.04M 1.06% 0.81% 2026-03-31
25 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 1,359,657 $7.89M 1.04% 0.79% 2026-03-31
8 filers$5.19M notional
# Filer Notional Value % of Total Period
1 Caption Management, LLC $2.34M 45.10% 2026-03-31
2 Stonepine Capital Management, LLC $1.62M 31.31% 2026-03-31
3 SUSQUEHANNA INTERNATIONAL GROUP, LLP Custodian $603.20K 11.63% 2026-03-31
4 IMC-Chicago, LLC Custodian $198.36K 3.82% 2026-03-31
5 Voss Capital, LP $130.50K 2.52% 2026-03-31
6 SIMPLEX TRADING, LLC Custodian $115.42K 2.23% 2026-03-31
7 GROUP ONE TRADING LLC Custodian $114.26K 2.20% 2026-03-31
8 CITADEL ADVISORS LLC Custodian $62.06K 1.20% 2026-03-31
6 filers$3.37M notional
# Filer Notional Value % of Total Period
1 Caption Management, LLC $2.57M 76.24% 2026-03-31
2 CITADEL ADVISORS LLC Custodian $318.42K 9.44% 2026-03-31
3 SUSQUEHANNA INTERNATIONAL GROUP, LLP Custodian $307.98K 9.13% 2026-03-31
4 JANE STREET GROUP, LLC Custodian $107.30K 3.18% 2026-03-31
5 SIMPLEX TRADING, LLC Custodian $35.96K 1.07% 2026-03-31
6 GROUP ONE TRADING LLC Custodian $31.90K 0.95% 2026-03-31
Fundamentals

Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.

Metrics
  • Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
  • Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
  • Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
  • Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
How to read the bars
  • Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
  • YoY growth — compare to the same quarter a year earlier to remove seasonality.
  • Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
  • Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.

TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.

P/B Ratio82.7
P/S Ratio3.4
EV/EBITDA24.6
ROE92.3%
Debt/Equity17.00