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TRV GP V, LLC — 13F Holdings & Portfolio

CIK 1990717 · latest 13F-HR filed 2026-05-07

Backtest portfolio

TRV GP V, LLC manages $401.0M in 13F-reported U.S. long-equity assets across 3 reported positions as of its 2026-03-31 13F-HR filing. Its largest disclosed positions are RAPP (55.68%), SEPN (37.25%), MAZE (7.08%). Quarter over quarter (versus its 2025-12-31 filing) the fund opened 0 new positions, exited 0, added to 0, and trimmed 2.

AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.

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AUM

$401.0M

Long-equity book

Holdings

3

Distinct positions

Period

2026-03-31

Filed 2026-05-07

Q/Q Activity

+0 / −0 / ↑0 / ↓2

vs 2025-12-31

Firm Profile & Key People
Name Title / Status Ownership Type

Top Adds (vs prior quarter)

  • No increased positions.
Show all 0 →

Top Trims

  • SEPTERNA, INC.-$23.9M -13.8%
  • MAZE THERAPEUTICS, INC.-$11.0M -28.0%
Show all 2 →

New Positions

  • No new positions this quarter.
Show all 0 →

Exited Positions

  • No exits this quarter.
Show all 0 →
All Holdings

Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).

# Issuer Symbol CUSIP Value Weight Shares Type
1 RAPPORT THERAPEUTICS, INC. RAPP 75383L102 $223.3M 55.68% 7,135,233 SH
2 SEPTERNA, INC. SEPN 81734D104 $149.4M 37.25% 6,215,591 SH
3 MAZE THERAPEUTICS, INC. MAZE 578784100 $28.4M 7.08% 950,800 SH
Filing History
Period Filed AUM Holdings Accession
2026-03-31 2026-05-07 $401.0M 3 0001193125-26-212010
2025-12-31 2026-02-13 $429.2M 3 0001193125-26-051785