JAMES S J MANUSO

CIK 1236365 · President and CEO · last filed 2026-04-22

JAMES S J MANUSO is a President and CEO who has filed 53 SEC Form 4 insider transactions across 4 companies since 2007. The most recent filing, for OCUP, was dated Apr 22, 2026. Across all open-market trades the lifetime net is −$549.8K, making them a net seller over the disclosed history. Current disclosed insider exposure totals $359.2K across reported positions.

"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.

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Disclosed Exposure

$359.2K

Companies

4

Total Filings

53

Lifetime Open-Market Net

-$549.8K

Holdings By Company

Latest on-record share count from this person's most recent non-derivative Form 4 transaction in each company. Disclosed exposure = shares × current underlying price.
Symbol Role Shares Price Disclosed Exposure Lifetime OM Net Filings Latest Filed
Opus Genetics, Inc. (OCUP) Delisted Director 317,318 $1.17 $371.3K $16.9K 18 2026-04-22
HURA Director $2.32 $0 3 2026-02-17
ASTX Chief Executive Officer 13,970 $25.71 $359.2K -$571.3K 8 2013-09-06
Astex Pharmaceuticals, Inc (SUPG) Delisted Chief Executive Officer 3,470 $4.6K 16 2011-07-22

Recent Filings

53 filings
Form 4 transactions across all companies, newest first.
Filed Symbol Action Net Shares Net $ Link
2026-04-22 Opus Genetics, Inc. (OCUP) Delisted Grant (A) +24,367 $0 EDGAR
2026-02-17 HURA Grant (A) $0 EDGAR
2026-01-05 Opus Genetics, Inc. (OCUP) Delisted Grant (A) +31,188 $0 EDGAR
2025-05-02 Opus Genetics, Inc. (OCUP) Delisted Grant (A) +79,504 $0 EDGAR
2025-01-06 HURA Grant (A) $0 EDGAR
2025-01-06 Opus Genetics, Inc. (OCUP) Delisted Grant (A) +50,222 $0 EDGAR
2024-10-22 HURA Grant (A) $0 EDGAR
2024-06-13 Opus Genetics, Inc. (OCUP) Delisted Grant (A) +41,143 $0 EDGAR
2024-01-03 Opus Genetics, Inc. (OCUP) Delisted Grant (A) +22,090 $0 EDGAR
2023-06-08 Opus Genetics, Inc. (OCUP) Delisted Grant (A) +10,976 $0 EDGAR
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Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (see filing footnote). Only P / S codes carry directional signal.