Opaleye Management Inc.
CIK 1595855 · last filed 2026-06-11
Opaleye Management Inc. is a corporate insider who has filed 198 SEC Form 4 insider transactions across 13 companies since 2015. The most recent filing shows the insider bought $183.7K of ACOG on Jun 11, 2026. Across all open-market trades the lifetime net is +$30.7M, making them a net buyer over the disclosed history. Current disclosed insider exposure totals $283.4M across reported positions.
"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.
$283.38M
13
198
$30.74M
Holdings By Company
| Symbol | Role | Shares | Price | Disclosed Exposure | Lifetime OM Net | Filings | Latest Filed |
|---|---|---|---|---|---|---|---|
| ACOG | 10%+ Owner | 2,644,889 | $5.99 | $15.84M | $3.08M | 14 | 2026-06-11 |
| SLGL | 10%+ Owner | 490,000 | $73.44 | $35.99M | $7.07M | 17 | 2026-05-22 |
| SNWV | 10%+ Owner | 5,000 | $14.91 | $74.5K | -$669.0K | 4 | 2026-05-04 |
| HROW | 10%+ Owner | 3,756,000 | $37.64 | $141.38M | -$6.77M | 9 | 2026-03-05 |
| CDXS | 10%+ Owner | 179,989 | $2.40 | $432.0K | $11.11M | 28 | 2025-12-15 |
| ETON | 10%+ Owner | 2,770,000 | $31.59 | $87.50M | -$7.05M | 14 | 2025-06-12 |
| HARROW, INC. (HROWM) Delisted | 10%+ Owner | 90,000 | $26.03 | $2.34M | -$571.8K | 16 | 2025-06-11 |
| TARA | 10%+ Owner | 51,500 | $3.90 | $200.8K | $5.07M | 24 | 2024-09-12 |
| Tracon Pharmaceuticals, Inc. (TCON) Delisted | 10%+ Owner | 0 | $0.03 | $0 | $7.74M | 36 | 2023-11-14 |
| TELA | 10%+ Owner | 124,813 | $0.86 | $107.3K | $3.99M | 19 | 2023-04-20 |
| HARROW, INC. (HROWL) Delisted | 10%+ Owner | 3,600,000 | $25.61 | $92.20M | $6.80M | 8 | 2022-12-14 |
| OCUL | 10%+ Owner | 207,500 | $8.94 | $1.86M | $137.9K | 3 | 2020-04-03 |
| HARROW, INC. (IMMY) Delisted | 10%+ Owner | 1,250,000 | — | — | $789.4K | 5 | 2016-03-14 |
Recent Filings
198 filings| Filed | Symbol | Action | Net Shares | Net $ | Link |
|---|---|---|---|---|---|
| 2026-06-11 | ACOG | Buy (P) | +30,728 | $183.7K | EDGAR |
| 2026-06-09 | ACOG | Buy (P) | +10,054 | $58.6K | EDGAR |
| 2026-05-29 | ACOG | Buy (P) | +73,738 | $434.7K | EDGAR |
| 2026-05-22 | ACOG | Buy (P) | +24,376 | $140.5K | EDGAR |
| 2026-05-22 | SLGL | Buy (P) | +1,563 | $100.7K | EDGAR |
| 2026-05-19 | ACOG | Buy (P) | +34,043 | $196.0K | EDGAR |
| 2026-05-14 | SLGL | Buy (P) | +3,437 | $231.5K | EDGAR |
| 2026-05-04 | SNWV | Sell (S) | −35,581 | -$574.2K | EDGAR |
| 2026-04-21 | SNWV | Sell (S) | −16,469 | -$337.0K | EDGAR |
| 2026-03-26 | ACOG | Buy (P) | +20,082 | $108.6K | EDGAR |