Opaleye Management Inc.
CIK 1595855 · last filed 2026-10-21
"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.
Charts
Trading activity, where the exposure sits, and each trade against the stock price.
ETON price and trades
Daily close with each Form 4 filing on this company marked: green = open-market buy, red = open-market sale, purple = grants, exercises, gifts and other non-market transactions. Marker size scales with the dollar value.
Shares held
Shares owned after each reported transaction on this company (direct holdings as reported).
Open-market buying and selling
by monthDollar value of open-market purchases (code P, up) and sales (code S, down) across all companies, by filing month. Grants, exercises and gifts are excluded.
Exposure by company
latestMost recently reported shares × current price. Faded bars (*) have had no filing in 3 years, so the person may no longer hold them. Click a bar to chart that company.
Filer Profile
SUITE 2600
BOSTON, MA 02108
Holdings By Company
| Symbol | Role | Shares | Price | Disclosed Exposure | Lifetime OM Net | Filings | Latest Filed |
|---|---|---|---|---|---|---|---|
| GRCE | 10%+ Owner | 2,948,610 | $1.83 | $5.40M | $433.6K | 9 | 2026-10-21 |
| ACOG | 10%+ Owner | 3,259,894 | $8.67 | $28.26M | $7.90M | 23 | 2026-10-19 |
| SLGL | 10%+ Owner | 538,507 | $70.65 | $38.05M | $11.23M | 25 | 2026-09-14 |
| ETON | 10%+ Owner | 2,665,000 | $50.29 | $134.02M | -$13.95M | 17 | 2026-07-17 |
| SNWV | 10%+ Owner | 5,000 | $5.21 | $26.1K | -$669.0K | 4 | 2026-05-04 |
| HROW | 10%+ Owner | 3,756,000 | $28.82 | $108.25M | -$6.77M | 9 | 2026-03-05 |
| CDXS | 10%+ Owner | 179,989 | $1.29 | $233.1K | $11.11M | 28 | 2025-12-15 |
| HARROW, INC. (HROWM) Delisted | 10%+ Owner | 90,000 | $26.03 | $2.34M | -$571.8K | 16 | 2025-06-11 |
| TARA | 10%+ Owner | 51,500 | $2.44 | $125.9K | $5.07M | 24 | 2024-09-12 |
| Tracon Pharmaceuticals, Inc. (TCON) Delisted | 10%+ Owner | 0 | $0.03 | $0 | $7.74M | 36 | 2023-11-14 |
| TELA | 10%+ Owner | 124,813 | $0.98 | $122.3K | $3.99M | 19 | 2023-04-20 |
| HARROW, INC. (HROWL) Delisted | 10%+ Owner | 3,600,000 | $25.61 | $92.20M | $6.80M | 8 | 2022-12-14 |
| OCUL | 10%+ Owner | 207,500 | $6.61 | $1.37M | $137.9K | 3 | 2020-04-03 |
| HARROW, INC. (IMMY) Delisted | 10%+ Owner | 1,250,000 | — | — | $789.4K | 5 | 2016-03-14 |
Recent Filings · Page 9 of 23
227 filings| Filed | Symbol | Action | Net Shares | Net $ | Link |
|---|---|---|---|---|---|
| 2025-05-14 | HARROW, INC. (HROWM) Delisted | Sell (S) | −15,000 | -$391.9K | EDGAR |
| 2025-05-14 | HARROW, INC. (HROWM) Delisted | Sell (S) | −5,000 | -$148.2K | EDGAR |
| 2025-05-14 | HARROW, INC. (HROWM) Delisted | Sell (S) | −5,000 | -$150.1K | EDGAR |
| 2025-05-02 | CDXS | Buy (P) | +45,000 | $104.1K | EDGAR |
| 2025-04-30 | SNWV | Buy (P) | +7,998 | $203.9K | EDGAR |
| 2025-04-29 | CDXS | Buy (P) | +25,000 | $55.9K | EDGAR |
| 2025-04-17 | CDXS | Buy (P) | +140,000 | $298.8K | EDGAR |
| 2025-04-09 | CDXS | Buy (P) | +100,000 | $198.4K | EDGAR |
| 2025-04-03 | CDXS | Buy (P) | +115,000 | $271.8K | EDGAR |
| 2025-03-26 | HARROW, INC. (HROWM) Delisted | Sell (S) | −5,000 | -$150.1K | EDGAR |
Notice (144 / 144/A): Form 144 is a notice of intent to sell restricted/control stock under Rule 144, filed before the sale; 144/A is an amendment. Many notices are pre-scheduled under Rule 10b5-1 plans. A Form 4 with code S typically follows within a few days when the planned sale executes; missing follow-up Form 4s suggest the notice was cancelled or modified.