Darren S Cline

CIK 1633639 · Chief Commercial Officer · last filed 2026-06-12

"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.

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Disclosed Exposure

$807.0K

Companies

7

Total Filings

52

Lifetime Open-Market Net

-$5.37M

Filer Profile

Reported Address
C/O XENON PHARMACEUTICALS INC.
3650 GILMORE WAY
BURNABY V5G 4W8
Profile details as reported on the filer's SEC submissions — for individual insiders the address is often in care of the issuer. Related filers are identified from jointly filed SEC submissions and shared reported addresses. View filings on SEC EDGAR.

Holdings By Company

Latest on-record share count from this person's most recent non-derivative Form 4 transaction in each company. Disclosed exposure = shares × current underlying price.
Symbol Role Shares Price Disclosed Exposure Lifetime OM Net Filings Latest Filed
PLRX Director $1.17 $0 5 2026-06-12
PYXS Director 251,405 $3.21 $807.0K $93.9K 7 2026-03-25
XENE Chief Commercial Officer $58.65 $0 2 2026-01-09
IPI Legacy Liquidation Co (IMPL) Delisted Director $0.24 $0 2 2023-06-20
GW PHARMACEUTICALS PLC (GWPH) Delisted U.S. Chief Commercial Officer 5,556 $218.96 $1.22M $0 5 2021-03-04
STEMLINE THERAPEUTICS INC (STML) Delisted Director 0 $0 3 2020-06-10
Seagen Inc. (SGEN) Delisted EVP, Commercial 72,556 $228.74 $16.60M -$5.46M 27 2018-11-30

Recent Filings · Page 2 of 6

52 filings
Insider activity across all companies, newest first. Form 4 rows are post-trade confirmations (buys, sells, grants, exercises). Notice (144) rows are pre-trade notices of intent to sell restricted or control stock under Rule 144 — they may not all execute. Compare adjacent dates to see which notices became actual sales.
Filed Symbol Action Net Shares Net $ Link
2023-04-14 IPI Legacy Liquidation Co (IMPL) Delisted Grant (A) $0 EDGAR
2023-03-28 PYXS Grant (A) +139,355 $0 EDGAR
2023-03-08 PLRX Grant (A) $0 EDGAR
2022-04-04 PYXS Grant (A) +66,831 $0 EDGAR
2021-12-09 PYXS Buy (P) +10,000 $93.9K EDGAR
2021-10-12 PYXS Grant (A) $0 EDGAR
2021-05-07 Disp (D) −5,556 $0
2021-03-04 GW PHARMACEUTICALS PLC (GWPH) Delisted Grant (A) $0 EDGAR
2021-02-24 GW PHARMACEUTICALS PLC (GWPH) Delisted Grant (A) $0 EDGAR
2020-06-10 STEMLINE THERAPEUTICS INC (STML) Delisted U −35,468 $0 EDGAR
Showing 1120 of 52
Page 2 of 6
Form 4 codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (see filing footnote). Only P / S codes carry directional signal.
Notice (144 / 144/A): Form 144 is a notice of intent to sell restricted/control stock under Rule 144, filed before the sale; 144/A is an amendment. Many notices are pre-scheduled under Rule 10b5-1 plans. A Form 4 with code S typically follows within a few days when the planned sale executes; missing follow-up Form 4s suggest the notice was cancelled or modified.