EVENTIDE ASSET MANAGEMENT, LLC — 13F Holdings & Portfolio
CIK 1442891 · latest 13F-HR filed 2026-08-14
EVENTIDE ASSET MANAGEMENT, LLC manages $7.48B in 13F-reported U.S. long-equity assets across 301 reported positions as of its 2026-06-30 13F-HR filing. Its largest disclosed positions are GH (3.93%), LRCX (3.90%), XMTR (2.78%). Quarter over quarter (versus its 2026-03-31 filing) the fund opened 60 new positions, exited 37, added to 172, and trimmed 45.
AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.
$7.48B
Long-equity book
301
Distinct positions
2026-06-30
Filed 2026-08-14
+60 / −37 / ↑172 / ↓45
vs 2026-03-31
Portfolio charts
Latest quarter's book, what changed, and how the portfolio has evolved across filings.
| Name | Title / Status | Ownership | Type |
|---|
Quarter-over-quarter changes
Share-count changes vs the prior 13F.
Top Adds (vs prior quarter)
- LAM RESEARCH CORP$145.2M +99.0%
- XOMETRY INC$87.6M +72.5%
- GUARDANT HEALTH INC$75.7M +34.7%
- DELL TECHNOLOGIES INC$63.4M +397.0%
- DATADOG INC$60.7M +214.6%
Top Trims
- ROPER TECHNOLOGIES INC-$32.4M -95.8%
- INSMED INC-$27.1M -30.3%
- WASTE CONNECTIONS INC-$24.9M -49.6%
- TRANSMEDICS GROUP INC-$18.1M -33.1%
- INTUIT-$12.9M -88.4%
New Positions
- AVALYN PHARMACEUTICALS INC$45.3M
- REMITLY GLOBAL INC$29.9M
- TD SYNNEX CORPORATION$27.0M
- ORUKA THERAPEUTICS INC$22.8M
- SPYRE THERAPEUTICS INC$17.9M
Exited Positions
- PROLOGIS INC.$56.1M
- GLOBAL E ONLINE LTD$37.6M
- CENTESSA PHARMACEUTICALS PLC$26.5M
- EQT CORP$25.5M
- ADC THERAPEUTICS SA$21.4M
Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).
| # | Issuer | Symbol | CUSIP | Value | Weight | Shares | Type |
|---|---|---|---|---|---|---|---|
| 1 | GUARDANT HEALTH INC | GH | 40131M109 | $293.8M | 3.93% | 1,957,828 | SH |
| 2 | LAM RESEARCH CORP | LRCX | 512807306 | $291.7M | 3.90% | 673,431 | SH |
| 3 | XOMETRY INC | XMTR | 98423F109 | $208.4M | 2.78% | 2,151,845 | SH |
| 4 | TRANE TECHNOLOGIES PLC | TT | G8994E103 | $203.5M | 2.72% | 415,039 | SH |
| 5 | MIRUM PHARMACEUTICALS INC | MIRM | 604749101 | $146.2M | 1.95% | 1,248,389 | SH |
| 6 | ASML HLDG NV | ASML | N07059210 | $136.0M | 1.82% | 68,410 | SH |
| 7 | TARGA RES CORP | TRGP | 87612G101 | $131.7M | 1.76% | 490,719 | SH |
| 8 | OLD DOMINION FREIGHT LINE IN | ODFL | 679580100 | $129.9M | 1.74% | 599,458 | SH |
| 9 | GE VERNOVA INC | GEV | 36828A101 | $124.7M | 1.67% | 106,999 | SH |
| 10 | UNITED RENTALS INC | URI | 911363109 | $117.2M | 1.57% | 103,445 | SH |
| 11 | ARGENX SE | ARGX | 04016X101 | $116.6M | 1.56% | 125,668 | SH |
| 12 | SCHOLAR ROCK HLDG CORP | SRRK | 80706P103 | $116.1M | 1.55% | 2,111,410 | SH |
| 13 | IRHYTHM HOLDINGS INC | IRTC | 450056106 | $104.7M | 1.40% | 880,338 | SH |
| 14 | KLA CORP | KLAC | 482480100 | $100.9M | 1.35% | 339,253 | SH |
| 15 | BETA BIONICS INC | BBNX | 08659B102 | $98.1M | 1.31% | 6,253,673 | SH |
| 16 | LATTICE SEMICONDUCTOR CORP | LSCC | 518415104 | $93.5M | 1.25% | 611,272 | SH |
| 17 | NVENT ELEC PLC | NVT | G6700G107 | $90.6M | 1.21% | 536,108 | SH |
| 18 | GENERAC HLDGS INC | GNRC | 368736104 | $89.8M | 1.20% | 306,850 | SH |
| 19 | DATADOG INC | DDOG | 23804L103 | $89.0M | 1.19% | 342,324 | SH |
| 20 | PALO ALTO NETWORKS INC | PANW | 697435105 | $85.7M | 1.14% | 251,535 | SH |
| 21 | ENTERGY CORP NEW | ETR | 29364G103 | $83.9M | 1.12% | 728,019 | SH |
| 22 | VAXCYTE INC | PCVX | 92243G108 | $80.2M | 1.07% | 1,380,219 | SH |
| 23 | MONOLITHIC PWR SYS INC | MPWR | 609839105 | $79.7M | 1.07% | 57,790 | SH |
| 24 | VISTRA CORP | VST | 92840M102 | $79.4M | 1.06% | 499,466 | SH |
| 25 | DELL TECHNOLOGIES INC | DELL | 24703L202 | $79.3M | 1.06% | 185,502 | SH |
| 26 | ROYALTY PHARMA PLC | RPRX | G7709Q104 | $77.7M | 1.04% | 1,380,261 | SH |
| 27 | AXSOME THERAPEUTICS INC. | AXSM | 05464T104 | $77.5M | 1.04% | 316,820 | SH |
| 28 | TERADYNE INC | TER | 880770102 | $71.4M | 0.95% | 147,984 | SH |
| 29 | D R HORTON INC | DHI | 23331A109 | $71.1M | 0.95% | 436,562 | SH |
| 30 | TOAST INC | TOST | 888787108 | $69.4M | 0.93% | 2,494,706 | SH |
| 31 | QUANTA SVCS INC | PWR | 74762E102 | $67.1M | 0.90% | 93,231 | SH |
| 32 | WILLIAMS COS INC | WMB | 969457100 | $66.9M | 0.89% | 898,241 | SH |
| 33 | METTLER TOLEDO INTERNATIONAL | MTD | 592688105 | $66.5M | 0.89% | 52,116 | SH |
| 34 | INSMED INC | INSM | 457669307 | $62.2M | 0.83% | 583,665 | SH |
| 35 | RB GLOBAL INC | RBA | 74935Q107 | $61.5M | 0.82% | 528,645 | SH |
| 36 | LIBERTY ENERGY INC | LBRT | 53115L104 | $60.6M | 0.81% | 2,314,729 | SH |
| 37 | BELITE BIO INC | BLTE | 07782B104 | $60.2M | 0.80% | 390,829 | SH |
| 38 | DT MIDSTREAM INC | DTM | 23345M107 | $59.8M | 0.80% | 407,626 | SH |
| 39 | KYMERA THERAPEUTICS INC | KYMR | 501575104 | $57.8M | 0.77% | 504,210 | SH |
| 40 | NASDAQ INC | NDAQ | 631103108 | $55.9M | 0.75% | 711,213 | SH |
| 41 | SITIME CORP | SITM | 82982T106 | $55.1M | 0.74% | 74,014 | SH |
| 42 | NISOURCE INC | NI | 65473P105 | $55.1M | 0.74% | 1,158,290 | SH |
| 43 | ELEMENT SOLUTIONS INC | ESI | 28618M106 | $54.7M | 0.73% | 1,149,055 | SH |
| 44 | NVIDIA CORPORATION | NVDA | 67066G104 | $54.4M | 0.73% | 273,735 | SH |
| 45 | ABIVAX SA | ABVX | 00370M103 | $52.6M | 0.70% | 394,957 | SH |
| 46 | VULCAN MATLS CO | VMC | 929160109 | $50.1M | 0.67% | 169,825 | SH |
| 47 | OREILLY AUTOMOTIVE INC | ORLY | 67103H107 | $50.0M | 0.67% | 544,082 | SH |
| 48 | TREVI THERAPEUTICS INC | TRVI | 89532M101 | $49.6M | 0.66% | 2,660,000 | SH |
| 49 | COLLEGIUM PHARMACEUTICAL INC | COLL | 19459J104 | $49.3M | 0.66% | 1,361,228 | SH |
| 50 | EASTGROUP PPTYS INC | EGP | 277276101 | $48.9M | 0.65% | 241,049 | SH |
| Period | Filed | AUM | Holdings | Accession |
|---|---|---|---|---|
| 2026-06-30 | 2026-08-14 | $7.48B | 301 | 0001580642-26-005306 |
| 2026-03-31 | 2026-05-15 | $6.05B | 278 | 0001580642-26-003193 |
| 2025-12-31 | 2026-02-13 | $6.40B | 268 | 0001580642-26-001080 |
| 2025-09-30 | 2025-11-14 | $6.08B | 240 | 0001580642-25-007287 |
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