Blue Water Life Science Advisors, LP — 13F Holdings & Portfolio
CIK 1789778 · latest 13F-HR filed 2026-08-14
Blue Water Life Science Advisors, LP manages $158.8M in 13F-reported U.S. long-equity assets across 9 reported positions as of its 2026-06-30 13F-HR filing. Its largest disclosed positions are CDNA (21.36%), TXG (15.50%), PSNL (14.15%). Quarter over quarter (versus its 2026-03-31 filing) the fund opened 0 new positions and exited 1; 6 existing positions rose in reported value and 2 fell.
AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.
Long-equity book
Distinct positions
Filed 2026-08-14
vs 2026-03-31
Portfolio charts
Latest quarter's book, what changed, and how the portfolio has evolved across filings.
Portfolio map
Q2 26Box size = position value; colour = change in share count vs the prior quarter (green added, red trimmed, blue new). Rows split across managers or share classes are combined. Click a box for the stock.
Sector mix
% of 13F valueSectors from each company's SIC code; funds and ETFs grouped separately.
Biggest buys and sells
Q1 26 → Q2 26Estimated from the change in shares held × the quarter-end price, so price moves alone don't count as buying. New and exited positions are included.
13F assets and positions
4 quartersTotal reported 13F value (bars) and number of positions (line) each quarter. Value changes include market moves.
Top positions over time
reported valueThe eight largest current positions, valued at each quarter end.
Concentration
top 10 = 100%Cumulative share of the portfolio held in the largest N positions.
As of the firm’s regulatory filing dated Mar 26, 2026.
| Name | Title / Status | Ownership | Type |
|---|---|---|---|
| BLUE WATER LIFE SCIENCE FUND GP, LLC Control | GENERAL PARTNER since Dec 2021 | Less than 5% | Domestic Entity |
| CORNELL, NATHANIEL, THOMAS Control | PORTFOLIO MANAGER AND MANAGING MEMBER AND CHIEF COMPLIANCE OFFICER since Apr 2017 | 75% or more | Individual |
| CORNELL, NATHANIEL, THOMAS Control Indirect owner via BLUE WATER LIFE SCIENCE FUND GP, LLC | GENERAL PARTNER since Dec 2021 | 75% or more | Individual |
Ownership & leadership changes · 5 filings with changes since Jan 4, 2021
From the firm’s regulatory filings, newest first. Dates are filing dates: a filing that no longer lists someone does not say when they left.
- No longer listedBLUE WATER LIFE SCIENCE ADVISORS GP, LLC · GENERAL PARTNER · Less than 5% · control person · listed since Dec 2021
- No longer listedCAFIERO, YOLANDA, LUCILLE · CHIEF COMPLIANCE OFFICER / CHIEF OPERATING OFFICER / CHIEF FINANCIAL OFFICER · Less than 5% · control person · listed since Mar 2024
- No longer listedCORNELL, NATHANIEL, THOMAS · GENERAL PARTNER · 75% or more · indirect via BLUE WATER LIFE SCIENCE ADVISORS GP, LLC · control person · listed since Dec 2021
- AddedBLUE WATER LIFE SCIENCE FUND GP, LLC · GENERAL PARTNER · Less than 5% · control person
- AddedCORNELL, NATHANIEL, THOMAS · GENERAL PARTNER · 75% or more · indirect via BLUE WATER LIFE SCIENCE FUND GP, LLC · control person
- ChangedCORNELL, NATHANIEL, THOMAS · title PORTFOLIO MANAGER AND MANAGING MEMBER → PORTFOLIO MANAGER AND MANAGING MEMBER AND CHIEF COMPLIANCE OFFICER
- No longer listedAPEADU, EVANS · CHIEF COMPLIANCE OFFICER AND CHIEF OPERATING OFFICER · Less than 5% · control person · listed since Mar 2021
- AddedCAFIERO, YOLANDA, LUCILLE · CHIEF COMPLIANCE OFFICER / CHIEF OPERATING OFFICER / CHIEF FINANCIAL OFFICER · Less than 5% · control person
- AddedBLUE WATER LIFE SCIENCE ADVISORS GP, LLC · GENERAL PARTNER · Less than 5% · control person
- AddedCORNELL, NATHANIEL, THOMAS · GENERAL PARTNER · 75% or more · indirect via BLUE WATER LIFE SCIENCE ADVISORS GP, LLC · control person
- ChangedAPEADU, EVANS · title CHIEF COMPLIANCE OFFICER AND CHIEF FINANCIAL OFFICER → CHIEF COMPLIANCE OFFICER AND CHIEF OPERATING OFFICER
- AddedAPEADU, EVANS · CHIEF COMPLIANCE OFFICER AND CHIEF FINANCIAL OFFICER · Less than 5% · control person
- ChangedCORNELL, NATHANIEL, THOMAS · title CHIEF COMPLIANCE OFFICER, PORTFOLIO MANAGER AND MANAGING MEMBER → PORTFOLIO MANAGER AND MANAGING MEMBER
- ListedCORNELL, NATHANIEL, THOMAS · CHIEF COMPLIANCE OFFICER, PORTFOLIO MANAGER AND MANAGING MEMBER · 75% or more · control person
Quarter-over-quarter changes
Changes in reported position value vs the prior 13F, so price moves count too, not just shares bought or sold.
Top Adds (vs prior quarter)
- CAREDX INC$17.7M +108.9%
- PERSONALIS INC$11.8M +110.4%
- ADAPTIVE BIOTECHNOLOGIES COR$7.6M +54.5%
- QUANTERIX CORP$7.5M +99.0%
- BILLIONTOONE INC$6.8M +432.0%
Blue Water Life Science Advisors, LP Holdings (2026-06-30)
Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).
| # | Issuer | Symbol | CUSIP | Value | Weight | Shares | Type |
|---|---|---|---|---|---|---|---|
| 1 | CAREDX INC | CDNA | 14167L103 | $33.9M | 21.36% | 1,190,000 | SH |
| 2 | 10X GENOMICS INC | TXG | 88025U109 | $24.6M | 15.50% | 642,000 | SH |
| 3 | PERSONALIS INC | PSNL | 71535D106 | $22.5M | 14.15% | 1,676,300 | SH |
| 4 | ADAPTIVE BIOTECHNOLOGIES COR | ADPT | 00650F109 | $21.7M | 13.65% | 1,010,145 | SH |
| 5 | GUARDANT HEALTH INC | GH | 40131M109 | $17.2M | 10.84% | 114,747 | SH |
| 6 | QUANTERIX CORP | QTRX | 74766Q101 | $15.0M | 9.45% | 3,474,202 | SH |
| 7 | NATERA INC | NTRA | 632307104 | $9.4M | 5.90% | 34,494 | SH |
| 8 | BILLIONTOONE INC | BLLN | 090168105 | $8.4M | 5.29% | 70,000 | SH |
| 9 | TEMPUS AI INC | TEM | 88023B103 | $6.1M | 3.85% | 105,412 | SH |
| Period | Filed | AUM | Holdings | Accession |
|---|---|---|---|---|
| 2026-06-30 | 2026-08-14 | $158.8M | 9 | 0001420506-26-001647 |
| 2026-03-31 | 2026-05-14 | $124.7M | 10 | 0001420506-26-001003 |
| 2025-12-31 | 2026-02-17 | $159.3M | 9 | 0001420506-26-000497 |
| 2025-09-30 | 2025-11-14 | $109.6M | 7 | 0001420506-25-003275 |
STE 4A
LARKSPUR, CA 94939