SAMUEL D ISALY

CIK 1055949 · last filed 2018-01-04

SAMUEL D ISALY is a corporate insider who has filed 36 SEC Form 4 insider transactions across 23 companies since 2008. The most recent filing shows the insider sold $37.7M of PIRS on Jan 4, 2018. Across all open-market trades the lifetime net is −$250.3M, making them a net seller over the disclosed history. Current disclosed insider exposure totals $2.05B across reported positions.

"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.

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Disclosed Exposure

$2.05B

Companies

23

Total Filings

36

Lifetime Open-Market Net

-$250.26M

Holdings By Company

Latest on-record share count from this person's most recent non-derivative Form 4 transaction in each company. Disclosed exposure = shares × current underlying price.
Symbol Role Shares Price Disclosed Exposure Lifetime OM Net Filings Latest Filed
PALVELLA THERAPEUTICS, INC. (PIRS) Delisted 10%+ Owner 68,759 $13.60 $935.1K -$40.22M 2 2018-01-04
Loxo Oncology, Inc. (LOXO) Delisted Director 1,191,000 -$109.49M 3 2017-11-27
X4 Pharmaceuticals, Inc (ASNS) Delisted 10%+ Owner 33 $0.08 $3 $0 1 2017-11-20
Roka BioScience, Inc. (ROKA) Delisted 10%+ Owner 0 -$1.44M 2 2017-10-05
BOLD 10%+ Owner 4,806,638 $2.48 $11.92M -$335.2K 1 2017-09-11
GKOS Director 1,628,111 $165.39 $269.27M -$89.00M 2 2017-08-17
KALA 10%+ Owner 951 $0.67 $641 $14.37M 1 2017-07-27
ALPINE IMMUNE SCIENCES, INC. (ALPN) Delisted Director 3,298,516 $64.97 $214.30M $0 1 2017-07-26
ASND Director 6,149,377 $255.23 $1.57B $15.00M 1 2017-03-28
CRVS Director 5,379,349 $13.39 $72.06M $464.3K 3 2016-06-27
OTONOMY, INC. (OTIC) Delisted Director 1,953,300 $0.08 $150.4K -$17.21M 1 2015-11-24
Sientra, Inc. (SIEN) Delisted 10%+ Owner 1,988 $0.17 $346 -$14.36M 1 2015-10-09
Sierra Oncology, Inc. (DNAI) Delisted Director 1,725,790 $8.93M 1 2015-07-21
INTERCEPT PHARMACEUTICALS, INC. (ICPT) Delisted Director 1,656,582 $19.00 $31.48M $0 2 2014-08-11
Anthera Pharmaceuticals Inc (ANTH) Delisted Director 27,531 $2.30M 2 2013-01-29
SUPN 10%+ Owner 0 $46.61 $0 -$6.19M 1 2012-12-19
GNOM 10%+ Owner 730,535 $54.46 $39.78M -$9.91M 1 2012-07-13
PCRX 10%+ Owner 2,546,100 $26.49 $67.45M -$1.40M 1 2012-02-29
CCXI 10%+ Owner 908,509 $13.87 $12.60M $0 1 2012-02-15
AMRN Director 345,455 $14.43 $4.98M -$1.72M 1 2011-03-07
NxStage Medical, Inc. (NXTM) Delisted Director 4,152,700 -$1.67M 2 2010-09-09
ALBIREO PHARMA, INC. (BIOD) Delisted Director 50,430 -$282.8K 1 2009-06-11
ATHERSYS, INC / NEW (ATHX) Delisted Director 137,920 $0.01 $1.9K $1.91M 2 2008-05-23

Recent Filings

36 filings
Insider activity across all companies, newest first. Form 4 rows are post-trade confirmations (buys, sells, grants, exercises). Notice (144) rows are pre-trade notices of intent to sell restricted or control stock under Rule 144 — they may not all execute. Compare adjacent dates to see which notices became actual sales.
Filed Symbol Action Net Shares Net $ Link
2018-01-04 PALVELLA THERAPEUTICS, INC. (PIRS) Delisted Sell (S) −5,128,860 -$37.70M EDGAR
2017-12-20 PALVELLA THERAPEUTICS, INC. (PIRS) Delisted Mixed -$1.60M EDGAR
2017-11-27 Loxo Oncology, Inc. (LOXO) Delisted Sell (S) −801,000 -$60.08M EDGAR
2017-11-20 X4 Pharmaceuticals, Inc (ASNS) Delisted Conv (C) +5,606,898 $15.00M EDGAR
2017-11-20 Loxo Oncology, Inc. (LOXO) Delisted Sell (S) −810,000 -$60.15M EDGAR
2017-10-05 Roka BioScience, Inc. (ROKA) Delisted Sell (S) −604,851 -$411.3K EDGAR
2017-10-02 Roka BioScience, Inc. (ROKA) Delisted Sell (S) −1,424,028 -$1.03M EDGAR
2017-09-11 BOLD Mixed -$109.8K EDGAR
2017-08-17 GKOS Sell (S) −975,000 -$36.98M EDGAR
2017-07-27 KALA Mixed +7,125,837 $14.37M EDGAR
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Form 4 codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (see filing footnote). Only P / S codes carry directional signal.
Notice (144 / 144/A): Form 144 is a notice of intent to sell restricted/control stock under Rule 144, filed before the sale; 144/A is an amendment. Many notices are pre-scheduled under Rule 10b5-1 plans. A Form 4 with code S typically follows within a few days when the planned sale executes; missing follow-up Form 4s suggest the notice was cancelled or modified.