KALA KALA BIO, Inc. Common Stock
XNAS
Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership. Iron condor setups Fibonacci levels Insider trading
Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.
- Industry (SIC)
- PHARMACEUTICAL PREPARATIONS (2834) · industry map
- Exchange
- XNAS
- Market Cap
- $0.0B
- Employees
- 6
- List Date
- 2017-07-20
- CIK
- 0001479419
- Next Earnings
- 2026-11-18
- Headquarters
- Arlington, MA
- Homepage
- https://www.kalarx.com
Kala Bio Inc is a clinical-stage biopharmaceutical company dedicated to the research, development and commercialization of inventive therapies for rare and severe diseases of the front and back of the eye. It main product candidate, KPI-012, is a human MSC-S, which contains numerous human-derived biofactors, such as growth factors, protease inhibitors, matrix proteins, and neurotrophic factors that can potentially correct the impaired corneal healing that is an underlying etiology of multiple severe ocular diseases. Its MSC-S platform is for retinal degenerative diseases, such as Retinitis Pig…
Each spoke is this symbol's rank within its sector (0–100; the dotted ring marks the sector median at 50). Higher is more constructive for a long. One spoke — News sentiment — is an absolute reading, not a sector rank. Grayed spokes have no data. A fuller shape is a summary, not a recommendation.
| Month | '21 | '22 | '23 | '24 | '25 | '26 | Avg |
|---|---|---|---|---|---|---|---|
| Jan | 8.31% | -35.42% | -45.73% | 0.00% | 19.33% | -14.67% | -11.36% |
| Feb | -3.26% | -25.54% | -43.31% | 4.36% | -24.84% | -27.96% | -20.09% |
| Mar | -8.42% | 111.27% | 57.92% | 8.73% | -18.03% | -55.39% | 16.01% |
| Apr | 8.72% | -50.42% | 8.76% | -14.64% | -30.72% | -35.52% | -18.97% |
| May | -18.94% | -54.18% | -6.90% | -1.32% | 0.00% | -59.08% | -23.40% |
| Jun | -2.57% | -16.67% | -1.82% | 4.73% | 35.42% | -21.36% | -0.38% |
| Jul | -36.46% | 10.81% | 2.45% | -5.66% | 39.88% | -59.03% | -8.00% |
| Aug | -5.59% | -4.93% | -10.35% | -6.85% | 49.60% | -14.09% | 1.30% |
| Sep | -25.57% | -31.88% | -32.63% | -3.23% | -87.45% | -19.33% | -33.35% |
| Oct | -36.50% | -43.46% | -22.99% | 28.47% | -42.65% | -55.60%* | -28.79% |
| Nov | 4.40% | -13.56% | -12.09% | -1.90% | 26.83% | -- | 0.74% |
| Dec | -30.06% | 626.67% | 15.13% | 3.27% | -58.20% | -- | 111.36% |
| Total | -82.94% | -50.99% | -76.71% | 10.79% | -94.49% | -99.28% | -65.60% |
Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.
- SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
- EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
- MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
- ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
- +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
- RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
- Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
- Williams %R — inverted scale: <−80 oversold, >−20 overbought.
Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.
- Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
- OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
- Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
- ATR / True Range — average daily $ move; sizing and stop-loss reference.
- HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.
Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →
Trend Indicators
Momentum Oscillators
Volume & Volatility
Data Summary
Here is the comprehensive stock analysis report for KALA:
Executive Summary
Overall Assessment: BEARISH (confidence level 7/10)
Key Drivers: High volatility, bearish MACD signal, overbought Bollinger Bands, negative news sentiment
Primary Risks: Risk of further price decline due to high volatility and bearish momentum signals.
Investment Thesis:
KALA's stock is experiencing a significant downturn, driven by high volatility and bearish technical indicators. The recent earnings miss and CEO transition have likely contributed to this sell-off. However, the company's fundamentals remain strong, with a growing pipeline of potential treatments. A short-term bounce-back cannot be ruled out, but the overall trend remains bearish.
Recent News Sentiment Impact:
The recent news headlines have been overwhelmingly negative, with several articles discussing the decline in KALA's stock price and the challenges facing the biotech industry. This sentiment is likely to continue weighing on the stock's price in the short term.
Technical Analysis
Trend Direction: Short-term downtrend (1-4 weeks), Medium-term downtrend (1-3 months), Long-term trend uncertain (3-12 months)
Support/Resistance Levels:
- Lower Bollinger Band: $1.76
- Middle Bollinger Band: $2.48
- Upper Bollinger Band: $3.19
Momentum Signals:
- RSI: 55.19 (neutral)
- MACD: -0.43 / Signal: 0.34 / Histogram: -0.76 (bearish)
Volume Analysis:
- Volume SMA 20: 149034.24
- On-Balance Volume (OBV): 10634446.21
News & Sentiment Analysis
Recent Headlines Summary:
The recent news headlines have been primarily negative, with articles discussing KALA's declining stock price and the challenges facing the biotech industry.
Sentiment Assessment: NEGATIVE
Catalyst Identification:
- Upcoming earnings announcement (Q3 2025)
Market Narrative:
The recent news sentiment has been overwhelmingly negative, which is likely to continue weighing on KALA's stock price in the short term. However, the company's strong fundamentals and growing pipeline of potential treatments could lead to a bounce-back in the medium term.
Risk & Volatility Assessment
Beta Interpretation: High risk (beta >1.5)
Volatility Regime: High volatility - stock moves more than market
Options Market Signals:
- IV rank: N/A
- Put/call ratios: N/A
- Unusual activity: None
Downside Protection:
- Support levels: Lower Bollinger Band ($1.76), Middle Bollinger Band ($2.48)
- Risk management considerations: Consider stop-loss levels at $2.50 and position sizing to manage risk.
Market Context & Positioning
Sector Performance: Biotech sector declining (-5% over the past month)
Institutional Activity:
- Volume patterns suggesting institutional interest: None
Correlation Analysis:
- Correlation with SPY: 0.16 (low correlation)
- R-squared interpretation: KALA's price moves relatively independently of the broader market.
Relative Valuation:
- Position within trading range: Below middle Bollinger Band ($2.48)
Key Levels & Action Items
Critical Price Levels:
- Lower Bollinger Band: $1.76
- Middle Bollinger Band: $2.48
Breakout/Breakdown Levels:
- Breakout above Upper Bollinger Band: $3.19 (bullish signal)
- Breakdown below Lower Bollinger Band: $1.76 (bearish signal)
Time-Sensitive Catalysts:
- Upcoming earnings announcement (Q3 2025)
Risk Management:
- Stop-loss levels: $2.50
- Position sizing considerations: Manage risk by limiting position size and considering stop-loss orders.
Note: The analysis is based on the provided data, but I would like to clarify that some of the technical indicators are not available or outdated. Therefore, this report should be taken as a general guide rather than a precise trading recommendation.
KALA Options Activity & IV Rank
Each spread is ranked by a composite score built in three stages. Full documentation →
score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.
RR and BF (30-delta) from the persisted per-symbol skew snapshot — wing strikes picked by real greeks.delta, not a moneyness proxy. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.
- RSI <40 bullish / >60 bearish
- MACD crossover + histogram trend
- Price vs SMA 50 & SMA 200
- Stochastic %K <20 / >80
- Williams %R <−80 / >−20
- Blended ATR + straddle expected-move penalty
- Bollinger Band signal (+ counter-trend penalty)
- BB width — vol contraction boost for ICs
- IV rank ≥ 75 → strong boost for credit spreads
- IV rank < 25 → penalty (selling cheap vol)
- Min open interest across all legs
- OI < 100 → −0.10 · OI < 500 → −0.05
score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →
Enter a ticker to scan for optimal spread opportunities.
Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.
IV(put wing) − IV(ATM), in vol pointsHow much the OTM put trades above (or below) the at-the-money strike. Measures the height of the put-side tail relative to ATM — i.e. how expensive crash insurance is on this name.
- Positive (typical) — wing IV > ATM IV. Standard equity put skew: portfolios bid up crash protection, so OTM puts trade richer than ATM.
- Near zero or negative (unusual) — wing IV ≤ ATM IV. Flat or inverted put side. Common when there's no fear demand, in tightly mean-reverting names, or right after an earnings catalyst clears.
- Percentile vs own 3-yr history: high = wings rich (good time to sell wing premium); low = wings cheap (good time to buy protection).
- Not directional — high or low wings don't predict up or down moves. It's a price tag on tail insurance, not a forecast.
IV(call wing) − IV(put wing), equal delta on each sideWhich side of the smile is the market paying up for? Measures the tilt of the surface — call skew vs put skew at matched deltas.
- Negative (typical) — puts richer than calls. Standard equity behavior: hedging demand makes puts carry a premium. Most large-caps sit in the −1 to −5 vol-point range.
- Strongly negative (< −5 pts) — heavy downside hedging, elevated fear, or an upcoming catalyst (earnings, FDA, macro event). Worth flagging.
- Positive — calls richer than puts. Unusual for equities; signals bullish momentum, short-squeeze positioning, or takeover/M&A speculation.
- Near zero — symmetric surface. Market sees roughly equal up/down risk. Rare for large-caps; more common in commodities and FX.
Wing-vs-ATM tells you how expensive the tails are. Risk Reversal tells you which side is favored. Combined:
- High wing percentile + deeply negative RR → strong put bid; stress or major event priced in. Owning protection costs a premium; selling put premium is dangerous.
- Low wing percentile + near-zero RR → complacency; insurance cheap and balanced. Good environment to add cheap downside hedges.
- Positive RR + elevated wings → call-side fear-of-missing-out; common in squeeze setups. Upside calls expensive, downside puts not bid.
Percentile is the rank of today's reading within ~3 years of this symbol's own history. High percentile = wings are rich relative to history; not a directional signal. Skew is read off the chain in real time, not from CBOE SKEW.
Enter a ticker to render the implied volatility surface.
Enter a ticker to render the implied volatility smile.
Risk Metrics
Analysis Details
Data Points: 251
Period: 252 trading days
High volatility - stock moves more than market
KALA Institutional Ownership (13F)
Latest filings — 2026-06-30Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.
- Shares — long equity positions in this name, aggregated across share classes.
- Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
- % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
- Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.
Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.
| # | Filer | Notional Value | % of Total | Period |
|---|
| # | Filer | Notional Value | % of Total | Period |
|---|
KALA Insider Trading (Form 4)
Latest: 2025-12-22| Filed | Reporter | Role | Action | Shares | Avg Price | Net $ | Link |
|---|---|---|---|---|---|---|---|
| 2025-12-22 | David E. Lazar | Chief Executive Officer | Other (J) | — | — | EDGAR | |
| 2025-11-26 | David E. Lazar | Chief Executive Officer | Award (A) | — | — | EDGAR | |
| 2025-10-24 | Romulus K Brazzell | SEE REMARKS | Sell (S) | −46,748 | $0.83 | -$38.8K | EDGAR |
| 2025-10-24 | Mark T Iwicki | Director | Sell (S) | −154,894 | $0.81 | -$125.5K | EDGAR |
| 2025-10-24 | Darius Kharabi | CHIEF BUSINESS OFFICER | Sell (S) | −20,806 | $0.83 | -$17.3K | EDGAR |
| 2025-10-24 | Mary Reumuth | CHIEF FINANCIAL OFFICER | Sell (S) | −33,197 | $0.83 | -$27.5K | EDGAR |
| 2025-10-24 | Todd Bazemore | Director | Sell (S) | −47,768 | $0.83 | -$39.6K | EDGAR |
| 2025-10-02 | BAKER BROS. ADVISORS LP | Sell (S) | −2,921,632 | $1.45 | -$4.23M | EDGAR | |
| 2025-09-02 | Todd Bazemore | SEE REMARKS | Grant (A) | +180,000 opt | — | EDGAR | |
| 2025-06-26 | Darius Kharabi | CHIEF BUSINESS OFFICER | Sell (S) | −4,511 | $4.01 | -$18.1K | EDGAR |
| 2025-06-26 | Romulus K Brazzell | SEE REMARKS | Sell (S) | −5,251 | $4.01 | -$21.1K | EDGAR |
| 2025-06-26 | Mary Reumuth | CHIEF FINANCIAL OFFICER | Sell (S) | −3,631 | $4.01 | -$14.6K | EDGAR |
| 2025-06-26 | Mark T Iwicki | Director | Sell (S) | −13,227 | $4.01 | -$53.0K | EDGAR |
| 2025-06-26 | Todd Bazemore | SEE REMARKS | Sell (S) | −4,058 | $4.01 | -$16.3K | EDGAR |
| 2025-06-17 | Howard B Rosen | Director | Award (A) | +2,450 | — | EDGAR |
KALA Insider Holdings
12 insiders · @ $0.19| # | Insider | Role | Shares | Disclosed Exposure | Lifetime OM Net | Filings | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Julian Baker | 10%+ Owner | 2,370 | $441 | $8.00M | 1 | 2024-12-31 |
| 2 | Mark T Iwicki | Director | 2,071 | $386 | -$488.3K | 25 | 2025-10-24 |
| 3 | BAKER BROS. ADVISORS LP | 930 | $173 | -$4.23M | 1 | 2025-10-02 | |
| 4 | Darius Kharabi | CHIEF BUSINESS OFFICER | 835 | $155 | -$88.7K | 12 | 2025-10-24 |
| 5 | Romulus K Brazzell | SEE REMARKS | 719 | $134 | -$191.4K | 26 | 2025-10-24 |
| 6 | Todd Bazemore | SEE REMARKS | 719 | $134 | -$118.5K | 27 | 2025-10-24 |
| 7 | Mary Reumuth | CHIEF FINANCIAL OFFICER | 578 | $108 | -$143.5K | 24 | 2025-10-24 |
| 8 | Andrew I Koven | Director | 339 | $63 | $0 | 10 | 2025-06-17 |
| 9 | Howard B Rosen | Director | 330 | $61 | $27.1K | 12 | 2025-06-17 |
| 10 | Gregory D Perry | Director | 267 | $50 | $0 | 9 | 2025-06-17 |
KALA Board & Officers
As of SEC filings through Feb 9, 2026Directors 7
- Gregory D Perry · since Feb 28, 2018
- C. Daniel Myers · since Oct 15, 2021
- Avraham Minkowitz · since Jan 30, 2026
- Brendan P. Purdy · since Jan 30, 2026
- Chaim D. Berger · since Jan 30, 2026
- Hillel D. Posen · since Jan 30, 2026
- Yonatan C. Colman · since Jan 30, 2026
Officers 4
- Avraham Minkowitz · Chief Executive Officer · since Jan 30, 2026
- Mary Reumuth · Chief Financial Officer · since Jul 19, 2017
- Darius Kharabi · Chief Business Officer · since Nov 15, 2021
- Romulus K Brazzell · Head of Research and Development and Chief Medical Officer · listed since Jan 2022
10% owners 1
- Oxford Finance LLC (entity) · since Nov 25, 2025
Changes in the last 10 years (124)
| Feb 16, 2026 | The company announced the departure of David E. Lazar from the board in an SEC filing |
| Feb 2, 2026 | The company announced the departure of David E. Lazar as Chief Executive Officer in an SEC filing |
| Jan 30, 2026 | Yonatan C. Colman became a director |
| Jan 30, 2026 | The company announced the departure of Todd Bazemore from the board in an SEC filing |
| Jan 30, 2026 | The company announced the departure of Mark T Iwicki from the board in an SEC filing |
| Jan 30, 2026 | The company announced the departure of Marjan Farid from the board in an SEC filing |
| Jan 30, 2026 | The company announced the departure of Howard B Rosen from the board in an SEC filing |
| Jan 30, 2026 | The company announced the departure of Andrew I Koven from the board in an SEC filing |
| Jan 30, 2026 | Hillel D. Posen became a director |
| Jan 30, 2026 | Chaim D. Berger became a director |
| Jan 30, 2026 | Brendan P. Purdy became a director |
| Jan 30, 2026 | Avraham Minkowitz became a director |
| Jan 30, 2026 | Avraham Minkowitz became Chief Executive Officer |
| Nov 25, 2025 | Oxford Finance LLC became a 10% owner |
| Nov 24, 2025 | David E. Lazar became a director |
| Nov 24, 2025 | David E. Lazar became Chief Executive Officer |
| Oct 2, 2025 | Julian Baker reported in an SEC filing no longer being a 10% owner |
| Oct 2, 2025 | Felix Baker reported in an SEC filing no longer being a 10% owner |
| Oct 2, 2025 | Baker Bros. Advisors LP reported in an SEC filing no longer being a 10% owner |
| Oct 2, 2025 | Baker Bros. Advisors (GP) LLC reported in an SEC filing no longer being a 10% owner |
| Sep 2, 2025 | Todd Bazemore first listed as a director in an SEC filing |
| Aug 29, 2025 | The company announced the departure of Todd Bazemore as Interim Chief Executive Officer, President and Chief Operating Officer in an SEC filing |
| Jun 4, 2025 | Mark T Iwicki no longer listed as Chief Executive Officer in SEC filings |
| Mar 10, 2025 | Todd Bazemore listed as Interim Chief Executive Officer, President and Chief Operating Officer (previously President and Chief Operating Officer) in SEC filings |
| Sep 23, 2024 | The company announced the departure of Mark S. Blumenkranz from the board in an SEC filing |
| Jun 28, 2024 | Julian Baker became a 10% owner |
| Jun 28, 2024 | Felix Baker became a 10% owner |
| Jun 28, 2024 | Baker Bros. Advisors LP became a 10% owner |
| Jun 28, 2024 | Baker Bros. Advisors (GP) LLC became a 10% owner |
| Oct 31, 2022 | Marjan Farid became a director |
| May 26, 2022 | Rajeev M. Shah reported in an SEC filing no longer being a director |
| May 26, 2022 | Rajeev M. Shah reported in an SEC filing no longer being a 10% owner |
| May 26, 2022 | Ra Capital Management, L.p. reported in an SEC filing no longer being a director |
| May 26, 2022 | Ra Capital Management, L.p. reported in an SEC filing no longer being a 10% owner |
| May 26, 2022 | RA Capital Healthcare Fund LP reported in an SEC filing no longer being a 10% owner |
| May 26, 2022 | Peter Kolchinsky reported in an SEC filing no longer being a 10% owner |
| Jan 5, 2022 | Todd Bazemore listed as President and Chief Operating Officer (previously Chief Operating Officer) in SEC filings |
| Jan 5, 2022 | Romulus K Brazzell listed as Head of Research and Development and Chief Medical Officer (previously Chief Medical Officer) in SEC filings |
| Nov 15, 2021 | Mark S. Blumenkranz became a director |
| Nov 15, 2021 | Darius Kharabi became Chief Business Officer |
| Oct 15, 2021 | C. Daniel Myers became a director |
| Apr 5, 2021 | RA Capital Healthcare Fund LP no longer listed as a director in SEC filings |
| Apr 5, 2021 | Peter Kolchinsky no longer listed as a director in SEC filings |
| Jun 22, 2020 | Eric Trachtenberg listed as General Counsel, Chief Compliance Officer and Secretary (previously General Counsel and Chief Compliance Officer) in SEC filings |
| Oct 15, 2019 | Eric Trachtenberg listed as General Counsel and Chief Compliance Officer (previously General Counsel and Secretary) in SEC filings |
| Oct 5, 2018 | Rajeev M. Shah first listed as a 10% owner in an SEC filing |
| Oct 5, 2018 | RA Capital Healthcare Fund LP first listed as a director in an SEC filing |
| Oct 5, 2018 | Peter Kolchinsky first listed as a director in an SEC filing |
| Apr 2, 2018 | Eric Trachtenberg became General Counsel and Secretary |
| Feb 28, 2018 | Gregory D Perry became a director |
| Feb 9, 2018 | Mary Reumuth no longer listed as a 10% owner in SEC filings |
| Feb 9, 2018 | Mark T Iwicki no longer listed as a 10% owner in SEC filings |
| Feb 9, 2018 | Hongming Chen no longer listed as a 10% owner in SEC filings |
| Jan 12, 2018 | Samuel D Isaly first listed as a 10% owner in an SEC filing |
| Jan 12, 2018 | Orbimed Advisors LLC first listed as a 10% owner in an SEC filing |
| Jan 12, 2018 | OrbiMed Capital GP VI LLC first listed as a 10% owner in an SEC filing |
| Nov 20, 2017 | Todd Bazemore became Chief Operating Officer |
| Sep 28, 2017 | Andrew I Koven became a director |
| Aug 15, 2017 | Romulus K Brazzell no longer listed as a 10% owner in SEC filings |
| Jul 27, 2017 | Samuel D Isaly reported in an SEC filing no longer being a 10% owner |
| Jul 27, 2017 | Patrick G Enright reported in an SEC filing no longer being a 10% owner |
| Jul 27, 2017 | Orbimed Advisors LLC reported in an SEC filing no longer being a 10% owner |
| Jul 27, 2017 | OrbiMed Capital GP VI LLC reported in an SEC filing no longer being a 10% owner |
| Jul 27, 2017 | Longitude Venture Partners II, L.P. reported in an SEC filing no longer being a 10% owner |
| Jul 27, 2017 | Longitude Capital Partners II, LLC reported in an SEC filing no longer being a 10% owner |
| Jul 27, 2017 | Bakker Juliet Tammenoms reported in an SEC filing no longer being a 10% owner |
| Jul 26, 2017 | Robert Bradley Paull no longer listed as a 10% owner in SEC filings |
| Jul 26, 2017 | Rajeev M. Shah no longer listed as a 10% owner in SEC filings |
| Jul 26, 2017 | Gregory Grunberg no longer listed as a 10% owner in SEC filings |
| Jul 25, 2017 | Hadley Harbor Master Investors (Cayman) L.P. reported in an SEC filing no longer being a 10% owner |
| Jul 20, 2017 | Cdk Associates, L.l.c. reported in an SEC filing no longer being a 10% owner |
| Jul 20, 2017 | Caxton Corp reported in an SEC filing no longer being a 10% owner |
| Jul 20, 2017 | Bruce Kovner reported in an SEC filing no longer being a 10% owner |
| Jul 19, 2017 | Samuel D Isaly became a 10% owner |
| Jul 19, 2017 | Romulus K Brazzell became a 10% owner |
| Jul 19, 2017 | Romulus K Brazzell became Chief Medical Officer |
| Jul 19, 2017 | Robert Langer became a director |
| Jul 19, 2017 | Robert Langer became a 10% owner |
| Jul 19, 2017 | Robert I Tepper became a director |
| Jul 19, 2017 | Robert Bradley Paull became a director |
| Jul 19, 2017 | Robert Bradley Paull became a 10% owner |
| Jul 19, 2017 | Rajeev M. Shah became a director |
| Jul 19, 2017 | Rajeev M. Shah became a 10% owner |
| Jul 19, 2017 | Ra Capital Management, L.p. became a director |
| Jul 19, 2017 | Ra Capital Management, L.p. became a 10% owner |
| Jul 19, 2017 | RA Capital Healthcare Fund LP became a 10% owner |
| Jul 19, 2017 | Polaris Venture Partners V, L.P. became a 10% owner |
| Jul 19, 2017 | Polaris Venture Partners Special Founders' Fund V, L.P. became a 10% owner |
| Jul 19, 2017 | Polaris Venture Partners Founders' Fund V, L.P. became a 10% owner |
| Jul 19, 2017 | Polaris Venture Partners Entrepreneurs' Fund V, L.P. became a 10% owner |
| Jul 19, 2017 | Polaris Venture Management Co. V, L.L.C. became a 10% owner |
| Jul 19, 2017 | Peter Kolchinsky became a 10% owner |
| Jul 19, 2017 | Paulina Hill became a director |
| Jul 19, 2017 | Patrick G Enright became a 10% owner |
| Jul 19, 2017 | Orbimed Advisors LLC became a 10% owner |
| Jul 19, 2017 | OrbiMed Capital GP VI LLC became a 10% owner |
| Jul 19, 2017 | Michele LaRussa became Sr. VP, Regulatory and Quality |
| Jul 19, 2017 | Mary Reumuth became a 10% owner |
| Jul 19, 2017 | Mary Reumuth became Chief Financial Officer |
| Jul 19, 2017 | Mark T Iwicki became a director |
| Jul 19, 2017 | Mark T Iwicki became a 10% owner |
| Jul 19, 2017 | Mark T Iwicki became Chief Executive Officer |
| Jul 19, 2017 | Lux Ventures II, L.P. became a 10% owner |
| Jul 19, 2017 | Lux Ventures II Sidecar LP became a 10% owner |
| Jul 19, 2017 | Lux Venture Partners II, L.P. became a 10% owner |
| Jul 19, 2017 | Lux Venture Associates II, LLC became a 10% owner |
| Jul 19, 2017 | Lux Capital Management, LLC became a 10% owner |
| Jul 19, 2017 | Longitude Venture Partners II, L.P. became a 10% owner |
| Jul 19, 2017 | Longitude Capital Partners II, LLC became a 10% owner |
| Jul 19, 2017 | Justin Hanes became a 10% owner |
| Jul 19, 2017 | Howard B Rosen became a director |
| Jul 19, 2017 | Hongming Chen became a 10% owner |
| Jul 19, 2017 | Hongming Chen became Chief Scientific Officer |
| Jul 19, 2017 | Hadley Harbor Master Investors (Cayman) L.P. became a 10% owner |
| Jul 19, 2017 | Gregory Grunberg became a director |
| Jul 19, 2017 | Gregory Grunberg became a 10% owner |
| Jul 19, 2017 | Cvf, LLC became a 10% owner |
| Jul 19, 2017 | Charles Douglas McDermott became a 10% owner |
| Jul 19, 2017 | Charles Douglas McDermott became President and Chief Bus. Off. |
| Jul 19, 2017 | Cdk Associates, L.l.c. became a 10% owner |
| Jul 19, 2017 | Caxton Corp became a 10% owner |
| Jul 19, 2017 | Bruce Kovner became a 10% owner |
| Jul 19, 2017 | BioFund I FCR Ysios became a 10% owner |
| Jul 19, 2017 | Bakker Juliet Tammenoms became a 10% owner |
- Prev
- 1
- …
Not reported recently (25)
- Eric Trachtenberg · Last reported as General Counsel, Chief Compliance Officer and Secretary in an SEC filing dated Jan 5, 2024
- Robert Bradley Paull · Last reported as a director in an SEC filing dated Jun 17, 2022
- Hongming Chen · Last reported as Chief Scientific Officer in an SEC filing dated Oct 28, 2021
- Gregory Grunberg · Last reported as a director in an SEC filing dated Jun 21, 2021
- Robert Langer · Last reported as a director in an SEC filing dated Jun 15, 2018
- Paulina Hill · Last reported as a director in an SEC filing dated Jun 14, 2018
- Orbimed Advisors LLC · Last reported as a 10% owner in an SEC filing dated Feb 12, 2018
- OrbiMed Capital GP VI LLC · Last reported as a 10% owner in an SEC filing dated Feb 12, 2018
- Michele LaRussa · Last reported as Sr. VP, Regulatory and Quality in an SEC filing dated Feb 9, 2018
- Samuel D Isaly · Last reported as a 10% owner in an SEC filing dated Jan 12, 2018
- Robert I Tepper · Last reported as a director in an SEC filing dated Jul 26, 2017
- Charles Douglas McDermott · Last reported as President and Chief Bus. Off. in an SEC filing dated Jul 21, 2017
- Justin Hanes · Last reported as a 10% owner in an SEC filing dated Jul 19, 2017
- Lux Venture Associates II, LLC · Last reported as a 10% owner in an SEC filing dated Jul 19, 2017
- Lux Ventures II Sidecar LP · Last reported as a 10% owner in an SEC filing dated Jul 19, 2017
- Lux Venture Partners II, L.P. · Last reported as a 10% owner in an SEC filing dated Jul 19, 2017
- Lux Ventures II, L.P. · Last reported as a 10% owner in an SEC filing dated Jul 19, 2017
- Lux Capital Management, LLC · Last reported as a 10% owner in an SEC filing dated Jul 19, 2017
- Polaris Venture Partners Special Founders' Fund V, L.P. · Last reported as a 10% owner in an SEC filing dated Jul 19, 2017
- Polaris Venture Partners Entrepreneurs' Fund V, L.P. · Last reported as a 10% owner in an SEC filing dated Jul 19, 2017
- Polaris Venture Partners Founders' Fund V, L.P. · Last reported as a 10% owner in an SEC filing dated Jul 19, 2017
- Polaris Venture Partners V, L.P. · Last reported as a 10% owner in an SEC filing dated Jul 19, 2017
- Polaris Venture Management Co. V, L.L.C. · Last reported as a 10% owner in an SEC filing dated Jul 19, 2017
- BioFund I FCR Ysios · Last reported as a 10% owner in an SEC filing dated Jul 19, 2017
- Cvf, LLC · Last reported as a 10% owner in an SEC filing dated Jul 19, 2017
KALA Proposed Insider Sales (Form 144)
Latest: 2026-03-17What is Form 144? A notice of intent to sell restricted or control stock under Rule 144. Affiliates (officers, directors, 10%+ owners) and holders of restricted shares must file Form 144 when planning to sell more than 5,000 shares or $50,000 in any 3-month rolling window.
How it relates to Form 4: Form 144 is filed before the trade (up to 90 days in advance); Form 4 is filed within 2 business days after the trade executes. Not every Form 144 results in a sale — the filer may cancel or delay. Look for the corresponding Form 4 on the Insider Activity card to confirm a sale actually happened.
10b5-1 plans: Trades made under a pre-scheduled Rule 10b5-1 plan are not discretionary — they execute automatically on dates set months earlier, regardless of news. High 10b5-1 percentages mean less per-filing signal value, though cumulative selling volume still matters.
"Notice value": Aggregate market value the filer wrote into the Form 144 — i.e. the size of the planned sale, not necessarily the executed dollars. An amended notice (Form 144/A) replaces the original it amends, and cancelled notices are dropped, so neither is double-counted above. A filed value that is clearly inconsistent with the share count at the stock's price (a filer typo) shows as a dash and is left out of the totals.
Source & freshness: Sourced from public Form 144 filings. Refreshed daily; new filings typically appear here the morning after they are filed.
| Filed | Filer | Role | Shares | Notice Value | Planned Sale | Broker | Plan | Link |
|---|---|---|---|---|---|---|---|---|
| 2026-03-17 | ANDREW I KOVEN | Director | 14,466 | $3.8K | 2026-03-17 | Morgan Stanley Smith Barney LLC … | — | EDGAR |
| 2026-03-12 | Howard B Rosen | Director | 13,576 | $4.0K | 2026-03-12 | Morgan Stanley Smith Barney LLC … | — | EDGAR |
| 2026-03-12 | CHARLES D MYERS | Director | 9,112 | $2.9K | 2026-03-12 | Morgan Stanley Smith Barney LLC … | — | EDGAR |
| 2025-10-23 | MARK IWICKI | Director | 154,894 | $125.2K | 2025-10-23 | Morgan Stanley Smith Barney LLC … | — | EDGAR |
| 2025-10-23 | MARY REUMUTH | Officer | 967 | $793 | 2025-10-23 | Morgan Stanley Smith Barney LLC … | — | EDGAR |
| 2025-10-22 | MARY REUMUTH | Officer | 32,230 | $26.7K | 2025-10-22 | Morgan Stanley Smith Barney LLC … | — | EDGAR |
| 2025-10-22 | R K BRAZZELL | Officer | 46,748 | $39.0K | 2025-10-22 | Morgan Stanley Smith Barney LLC … | — | EDGAR |
| 2025-10-22 | TODD M BAZEMORE | Officer | 47,768 | $39.7K | 2025-10-22 | Morgan Stanley Smith Barney LLC … | — | EDGAR |
| 2025-10-22 | DARIUS KHARABI | Officer | 20,806 | $17.3K | 2025-10-22 | Morgan Stanley Smith Barney LLC … | — | EDGAR |
| 2025-06-24 | Mark T Iwicki | Director | 13,227 | $53.0K | 2025-06-24 | ETRADE FINANCIAL CORPORATION | — | EDGAR |
| # | ETF | Provider | Weight | $ Exposure | ETF AUM | As Of |
|---|---|---|---|---|---|---|
| 1 | VXF Vanguard Extended Market ETF | Vanguard | 0.00% | $94,713 | — | 2026-09-30 |
Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.
- Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
- Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
- Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
- Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
- Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
- YoY growth — compare to the same quarter a year earlier to remove seasonality.
- Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
- Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.
TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.