Fred A Middleton

CIK 1267959 · last filed 2026-06-29

Fred A Middleton is a corporate insider who has filed 129 SEC Form 4 insider transactions across 10 companies since 2007. The most recent filing shows the insider bought $200.0K of CALC on Jun 29, 2026. Across all open-market trades the lifetime net is −$73.5M, making them a net seller over the disclosed history. Current disclosed insider exposure totals $2.7M across reported positions. 14 SEC filings were submitted jointly with Pacira BioSciences, Inc.

"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.

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Disclosed Exposure

$2.73M

Companies

10

Total Filings

129

Lifetime Open-Market Net

-$73.53M

Filer Profile

Reported Address
1300 S. EL CAMINO REAL STE 203
SAN MATEO, CA 94402-1708
Formerly Known As
MIDDLETON FRED A (2004–2025)
Related Filers
Pacira BioSciences, Inc. — 14 joint filings, latest 2013-06-25
Sanderling VI Beteiligungs GmbH & Co KG — 3 joint filings, latest 2013-04-15
Sanderling VI Limited Partnership — 3 joint filings, latest 2013-04-15
Sanderling Venture Partners VI LP — 3 joint filings, latest 2013-04-15
Sanderling Venture Partners VI Co Investment Fund LP — 2 joint filings, latest 2013-04-15
Sanderling Ventures Management VI — 2 joint filings, latest 2013-04-15
SANDERLING VENTURE PARTNERS IV CO INVESTMENT FUND LP — 1 joint filings, latest 2013-04-15
Profile details as reported on the filer's SEC submissions — for individual insiders the address is often in care of the issuer. Related filers are identified from jointly filed SEC submissions and shared reported addresses. View filings on SEC EDGAR.

Holdings By Company

Latest on-record share count from this person's most recent non-derivative Form 4 transaction in each company. Disclosed exposure = shares × current underlying price.
Symbol Role Shares Price Disclosed Exposure Lifetime OM Net Filings Latest Filed
CALC Director 196,652 $1.98 $389.4K $2.77M 9 2026-06-29
CHIMERIX INC (CMRX) Delisted Director 0 $8.54 $0 $464.2K 20 2025-04-21
CalciMedica, Inc. (SCPH) Delisted Director 39,170 $5.67 $222.1K $404.0K 2 2024-11-05
CalciMedica, Inc. (GRAY) Delisted Director 17,682 $5.50 $97.3K $0 1 2023-03-22
ENDOCYTE INC (ECYT) Delisted Director 0 $5.32M 16 2018-12-21
STXS Director 343,244 $1.29 $442.8K $5.97M 50 2018-03-05
Stereotaxis, Inc. (STXS.R) Delisted Director $0 4 2013-11-22
PCRX Director 70,399 $25.36 $1.79M -$61.29M 10 2013-06-25
BEAT Director 279,237 $0.41 $113.5K -$27.16M 11 2010-05-11
MMRGlobal, Inc. (FVRL) Delisted Director 116,678 $0 2 2007-11-06

Recent Filings

129 filings
Insider activity across all companies, newest first. Form 4 rows are post-trade confirmations (buys, sells, grants, exercises). Notice (144) rows are pre-trade notices of intent to sell restricted or control stock under Rule 144 — they may not all execute. Compare adjacent dates to see which notices became actual sales.
Filed Symbol Action Net Shares Net $ Link
2026-06-29 CALC Buy (P) +248,972 $200.0K EDGAR
2025-06-26 CALC Grant (A) $0 EDGAR
2025-04-21 CHIMERIX INC (CMRX) Delisted Disp (D) −3,615,477 -$30.91M EDGAR
2024-12-06 CALC Buy (P) +4,800 $12.7K EDGAR
2024-11-05 CalciMedica, Inc. (SCPH) Delisted Buy (P) +107,744 $404.0K EDGAR
2024-10-30 CHIMERIX INC (CMRX) Delisted Gift (G) −60,000 $0 EDGAR
2024-08-28 CalciMedica, Inc. (SCPH) Delisted Grant (A) $0 EDGAR
2024-06-21 CHIMERIX INC (CMRX) Delisted Grant (A) $0 EDGAR
2024-04-22 CALC Grant (A) $0 EDGAR
2024-01-25 CALC Buy (P) +679,384 $2.52M EDGAR
Showing 110 of 129
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Form 4 codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (see filing footnote). Only P / S codes carry directional signal.
Notice (144 / 144/A): Form 144 is a notice of intent to sell restricted/control stock under Rule 144, filed before the sale; 144/A is an amendment. Many notices are pre-scheduled under Rule 10b5-1 plans. A Form 4 with code S typically follows within a few days when the planned sale executes; missing follow-up Form 4s suggest the notice was cancelled or modified.