CALC CalciMedica, Inc. Common Stock
XNAS
0.69
Delayed
Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership. Iron condor setups Fibonacci levels Insider trading
Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.
- 52-Week Range
- $1.00 – $36.00
- YTD
- -97.95%
- Straddle Price
- $2.48
- P/C Vol Ratio
- 0.10
- Market Cap
- $0.0B
- Open
- $1.26
- Day Range
- $1.25 – $1.50
- Volume
- 157,985
- Prev Close
- $1.23
A blended fair-value estimate combining up to six valuation methods. Each method is weighted by how well it fits the company — DCF down-weights for unprofitable names; DDM only fires for steady dividend payers; comparables down-weight when peer multiples disagree.
- DCF (quality-aware) — projects free cash flow with a horizon that scales to business quality. True compounders (quality 6/6) get 10 years explicit + 10 years fade before terminal; cyclical/struggling names (quality 0-1) get a 5-year terminal cliff. Quality is scored from ROE, gross margin, growth, FCF margin, debt load, and FCF consistency — the same factors that drive market premium for compounders.
- Market-Implied Growth (in Model Inputs) — reverse-DCF that answers "what growth rate is the market pricing in?". Lets you sanity-check the deviation: if implied growth is plausible for the business, the model's bearish flag may be wrong; if implausible, the market may be over-extrapolating.
- DDM (Gordon Growth Dividend Model) — values the stream of future dividends. Only used when trailing yield ≥ 2% and dividend payments are stable — below that the dividend is a token payout and Gordon (which values only the dividend stream) systematically underprices growth names, so those route to DCF + comparables + market anchor instead.
- P/E, EV/EBITDA, P/B, P/S — applies the peer-group median multiple to this company's per-share metric. Peers come from the same set as the "Related symbols" card. Earnings/sales metrics are forward-tilted by the company's recent revenue growth (capped at 25%) so they're comparable to peers' growth-embedded multiples — mimics how analysts use NTM rather than TTM. Per-multiple weights are biased by company quality (e.g. P/B down-weighted for asset-light tech).
- Market Anchor (SMA50) — the 50-day moving average, weighted by recent trading-range stability (tighter Bollinger bands → higher weight). Captures information fundamentals miss (forward consensus, sentiment, supply/demand) — but only when recent trading is steady enough that the market has converged on a view. During wild breakouts or breakdowns the anchor's weight collapses.
- Options Expected (B-L 30d) — the risk-neutral expected stock price at 30-day options expiration, derived from the full implied-volatility surface via Breeden-Litzenberger (second derivative of call price wrt strike → implied PDF, then E[S_T]). Forward-looking, captures all options-implied information (smile, skew, term structure) in one number. Weighted by chain liquidity. SP500-only at present (pre-computed daily). Backtest evidence: adds modest alpha across most bucket × holding combos.
- Blended value — weighted average. Confidence reflects how many methods fired and how tight peer dispersion is.
- Deviation pill — green when blended FV ≥ 10% above current price (undervalued); red when ≥ 10% below; grey otherwise.
| 10-yr Treasury (rf) | 4.96% |
| Beta vs SPY | 0.69 |
| Cost of Equity (CAPM) | 8.41% (VRP-adj) |
| WACC | 7.49% |
| Volatility Risk Premium | +398.8pp (IV − HV30) |
| Effective Tax Rate | 21.0% |
| Rev. Growth (YoY, DCF input) | +3.0% |
| DCF Horizon | 5 years explicit + fade |
| Forward Tilt (NTM/TTM) | ×1.03 (applied to P/E, EV/EBITDA, P/S) |
| Free Cash Flow (TTM) | $-0.0B |
| Return on Equity (TTM) | -385.3% |
| Book / Price | 26.4% |
| Debt / Equity | 1.67 |
| Quality Score | 0/6 — cyclical/struggling (5y DCF) |
| SMA 50 | $1.88 (Market Anchor value) |
| SMA 20 / Bollinger Mid | $1.30 |
| Bollinger Width / SMA20 | 5112.9% (drives anchor stability) |
| Net Debt | $-0.0B |
| Market Cap | $0B |
| Method | Implied Price | Weight | Detail |
|---|---|---|---|
| DCF | n/a | 0% | |
| DDM (Gordon) | n/a | 0% | |
| Peer P/E | n/a | 0% | median 39.5× · 3 peers |
| Peer EV/EBITDA | n/a | 0% | median 19.2× · 3 peers |
| Peer P/B | $1.20 | 19% | median 3.5× · 3 peers |
| Peer P/S | n/a | 0% | median 3.9× · 3 peers |
| Market Anchor (SMA50) | $1.88 | 81% | stability 85% (BB-width) |
| Options Expected (B-L 30d) | n/a | 0% |

- Industry (SIC)
- PHARMACEUTICAL PREPARATIONS (2834) · industry map
- Exchange
- XNAS
- Market Cap
- $0.0B
- Employees
- 15
- List Date
- 2020-09-25
- CIK
- 0001534133
- Next Earnings
- 2026-11-11 (After-Close)
- EPS Forecast
- ($0.75) (1 est.)
- Headquarters
- La Jolla, CA
- Homepage
- https://www.calcimedica.com
CalciMedica Inc is a clinical-stage biopharmaceutical company focused on developing therapeutics that treat serious illnesses driven by inflammatory and immunologic processes and direct cellular damage. Its product candidates act upon calcium release-activated calcium (CRAC) channels and would constitute a new class of drugs. Its product candidate is Auxora, a potent and selective intravenous formulated small molecule CRAC channel inhibitor containing the active compound zegocractin (formerly referred to as CM4620) that, in animal models, reduced acute epithelial and/or endothelial cell injury…
Each spoke is this symbol's rank within its sector (0–100; the dotted ring marks the sector median at 50). Higher is more constructive for a long. One spoke — News sentiment — is an absolute reading, not a sector rank. Grayed spokes have no data. A fuller shape is a summary, not a recommendation.
| Month | '23 | '24 | '25 | '26 | Avg |
|---|---|---|---|---|---|
| Jan | -- | 142.74% | -22.19% | -86.65% | 11.30% |
| Feb | -- | -29.35% | -15.91% | -22.94% | -22.73% |
| Mar | -21.01% | -6.94% | -13.18% | 6.51% | -8.66% |
| Apr | 9.94% | 45.80% | -19.49% | 0.31% | 9.14% |
| May | 7.89% | -4.70% | 10.32% | 38.80% | 13.08% |
| Jun | -15.76% | -30.40% | -2.44% | 22.33% | -6.57% |
| Jul | -10.94% | 9.88% | 120.51% | -3.85% | 28.90% |
| Aug | -7.01% | -6.92% | -8.16% | -43.14% | -16.31% |
| Sep | -17.26% | -1.34% | -0.78% | -19.00% | -9.60% |
| Oct | -11.65% | -12.53% | -3.27% | -21.21%* | -12.17% |
| Nov | 93.02% | -1.71% | 42.81% | -- | 44.71% |
| Dec | -27.23% | 3.21% | 53.61% | -- | 9.86% |
| Total | -32.88% | 38.19% | 109.88% | -93.49% | 5.43% |
Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.
- SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
- EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
- MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
- ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
- +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
- RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
- Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
- Williams %R — inverted scale: <−80 oversold, >−20 overbought.
Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.
- Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
- OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
- Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
- ATR / True Range — average daily $ move; sizing and stop-loss reference.
- HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.
Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →
Trend Indicators
Momentum Oscillators
Volume & Volatility
Data Summary
LLM Stock Analysis Report
SYMBOL: CALC
Executive Summary Overall Assessment: NEUTRAL (Confidence Level: 6/10) Key Drivers:
- Technical indicators suggest a neutral market with no clear trend
- Recent news headlines show mixed sentiment, with no significant catalysts impacting the stock price
Primary Risks:
- Low volatility and beta indicate low risk, but could also mean limited upside potential
- Options market pricing suggests a $0.50 move by expiration, which may not be significant enough to drive meaningful returns
2-3 sentence investment thesis: Calcimedica (CALC) presents a neutral investment opportunity with no clear direction or catalysts driving the stock price. While the company has shown promise in its CARPO trial for Auxora™ in acute pancreatitis, recent news headlines have been mixed and may not be enough to move the needle significantly.
Recent News Sentiment Impact: The most significant recent news headline is the announcement of the first patient enrolled in the international expansion of the CARPO trial (GlobeNewswire Inc., 2023-08-09). This neutral sentiment event did not appear to impact the stock price significantly.
Technical Analysis Trend Direction:
- Short-term: Neutral (no clear trend)
- Medium-term: Uptrend (SMA 50 above SMA 20 and 200)
- Long-term: Downtrend (SMA 200 below SMA 50 and 20)
Support/Resistance Levels:
- Key price levels to monitor include the upper Bollinger Band ($0.89), middle band ($0.67), and lower band ($0.46).
Momentum Signals:
- RSI (14): Neutral at 36.60
- MACD: Bearish with a histogram of -0.21
Volume Analysis:
- Volume SMA 20: 293624.39
- On-Balance Volume (OBV): -49807898.00
- Volume Rate of Change: -43.01%
News & Sentiment Analysis Recent Headlines Summary: The most recent news headlines are neutral, with no clear trend or catalyst driving the stock price.
Sentiment Assessment: Aggregate news sentiment is NEUTRAL due to mixed signals from various sources.
Catalyst Identification: There are no immediate (1-7 days) or near-term (1-4 weeks) catalysts that could significantly impact the stock price.
Market Narrative: The market narrative suggests a neutral market with no clear direction, which aligns with the technical indicators and news sentiment.
Risk & Volatility Assessment Beta Interpretation: CALC has a low beta of 0.30 compared to SPY, indicating low risk relative to the overall market.
Volatility Regime: Current volatility is low (1.34), with no significant changes expected in the near term.
Options Market Signals: IV Rank: Medium (42.4%), indicating historically average volatility Put/Call Volume Ratio: Neutral (1.22), suggesting no strong sentiment bias
Downside Protection: Support levels to monitor include the lower Bollinger Band ($0.46) and SMA 20 ($0.67).
Market Context & Positioning Sector Performance: CALC is performing similarly to its sector peers, with no significant relative strength or weakness.
Institutional Activity: There is moderate institutional interest in CALC, with a volume flow of 18 calls vs 22 puts.
Correlation Analysis: CALC has a low correlation (0.04) with the overall market, indicating limited sensitivity to broader market movements.
Relative Valuation: CALC is trading near its long-term moving averages, suggesting no clear relative value or over/under valuation.
Key Levels & Action Items Critical Price Levels:
- Upper Bollinger Band ($0.89)
- Middle band ($0.67)
- Lower band ($0.46)
Breakout/Breakdown Levels:
- SMA 20 ($0.67) and SMA 50 ($1.03)
Time-Sensitive Catalysts: No immediate or near-term catalysts are expected to significantly impact the stock price.
Risk Management: Stop-loss levels should be set at the lower Bollinger Band ($0.46), with position sizing considerations based on volatility and beta.
Data Interpretation Guidelines RSI: 36.60 (neutral) MACD: Bearish with a histogram of -0.21 Moving Averages: No clear trend direction
News Impact Assessment: Recent news headlines are neutral, with no significant impact on the stock price.
Risk Assessment Criteria: High Risk: None Medium Risk: None Low Risk: Low volatility and beta indicate low risk
Output Format Requirements Be Objective: Present both bullish and bearish cases. Use Specific Data: Reference actual numbers from technical indicators. Highlight Conflicts: Note when technical and news signals diverge. Assess Data Quality: Comment on data completeness and reliability.
This comprehensive analysis provides a neutral investment thesis for CALC, highlighting the importance of monitoring key price levels, institutional activity, and options market signals. The report also notes the low risk profile of the stock, which may not be sufficient to drive meaningful returns in the near term.
| Earnings Date | Timing | Expected Move | Actual Move | Ratio | Outcome |
|---|---|---|---|---|---|
| 2023-11-02 | After-Close | 334.74% | 20.25% | 0.06x | Within |
| 2026-03-03 | After-Close | 172.35% | 7.55% | 0.04x | Within |
Earnings calendar: this week’s reports with expected vs actual moves →
CALC Options Activity & IV Rank
Volatility Metrics
Options Flow
ATM Options Pricing
Chain Summary
Each spread is ranked by a composite score built in three stages. Full documentation →
score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.
RR and BF (30-delta) from the persisted per-symbol skew snapshot — wing strikes picked by real greeks.delta, not a moneyness proxy. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.
- RSI <40 bullish / >60 bearish
- MACD crossover + histogram trend
- Price vs SMA 50 & SMA 200
- Stochastic %K <20 / >80
- Williams %R <−80 / >−20
- Blended ATR + straddle expected-move penalty
- Bollinger Band signal (+ counter-trend penalty)
- BB width — vol contraction boost for ICs
- IV rank ≥ 75 → strong boost for credit spreads
- IV rank < 25 → penalty (selling cheap vol)
- Min open interest across all legs
- OI < 100 → −0.10 · OI < 500 → −0.05
score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →
Enter a ticker to scan for optimal spread opportunities.
Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.
Not enough history yet to rank today's net dealer gamma against this name's own record.
Net dealer gamma is an estimate of the aggregate gamma held by options market makers across this name's option chain, weighted by open interest. Dealer positions aren't public, so it uses a standard simplifying assumption: dealers are treated as long the calls and short the puts that are open. Actual dealer books can differ.
Gamma percentile ranks today's estimate against this name's own daily history, from 0% (the lowest reading on record) to 100% (the highest). Raw gamma scales with how much open interest a chain carries, so it isn't comparable across names; the percentile is. The badge marks the bottom 20% as low and the top 20% as high.
Tilts run from −1 to +1 and show how lopsided the estimated dealer exposure is. GEX tilt compares call gamma with put gamma. Vanna tilt describes how the hedge would shift if implied volatility changed, and charm tilt how it would shift with the passage of time.
This card describes estimated positioning and where it sits historically. It is not a forecast of price direction or volatility and not a trading signal. Market-wide view: Dealer positioning screener.
IV(put wing) − IV(ATM), in vol pointsHow much the OTM put trades above (or below) the at-the-money strike. Measures the height of the put-side tail relative to ATM — i.e. how expensive crash insurance is on this name.
- Positive (typical) — wing IV > ATM IV. Standard equity put skew: portfolios bid up crash protection, so OTM puts trade richer than ATM.
- Near zero or negative (unusual) — wing IV ≤ ATM IV. Flat or inverted put side. Common when there's no fear demand, in tightly mean-reverting names, or right after an earnings catalyst clears.
- Percentile vs own 3-yr history: high = wings rich (good time to sell wing premium); low = wings cheap (good time to buy protection).
- Not directional — high or low wings don't predict up or down moves. It's a price tag on tail insurance, not a forecast.
IV(call wing) − IV(put wing), equal delta on each sideWhich side of the smile is the market paying up for? Measures the tilt of the surface — call skew vs put skew at matched deltas.
- Negative (typical) — puts richer than calls. Standard equity behavior: hedging demand makes puts carry a premium. Most large-caps sit in the −1 to −5 vol-point range.
- Strongly negative (< −5 pts) — heavy downside hedging, elevated fear, or an upcoming catalyst (earnings, FDA, macro event). Worth flagging.
- Positive — calls richer than puts. Unusual for equities; signals bullish momentum, short-squeeze positioning, or takeover/M&A speculation.
- Near zero — symmetric surface. Market sees roughly equal up/down risk. Rare for large-caps; more common in commodities and FX.
Wing-vs-ATM tells you how expensive the tails are. Risk Reversal tells you which side is favored. Combined:
- High wing percentile + deeply negative RR → strong put bid; stress or major event priced in. Owning protection costs a premium; selling put premium is dangerous.
- Low wing percentile + near-zero RR → complacency; insurance cheap and balanced. Good environment to add cheap downside hedges.
- Positive RR + elevated wings → call-side fear-of-missing-out; common in squeeze setups. Upside calls expensive, downside puts not bid.
Percentile is the rank of today's reading within ~3 years of this symbol's own history. High percentile = wings are rich relative to history; not a directional signal. Skew is read off the chain in real time, not from CBOE SKEW.
Enter a ticker to render the implied volatility surface.
Enter a ticker to render the implied volatility smile.
Risk Metrics
Analysis Details
Data Points: 251
Period: 252 trading days
Low volatility - stock moves less than market
| Investor | Value | Share of their portfolio | Rank | Q/Q shares | Source |
|---|---|---|---|---|---|
| Renaissance Technologies Hedge fund Jim Simons | $100K | #2977 of 3138 | -24.0% | 13F | |
| Rockefeller Capital Management Family office Rockefeller family | $21K | #3719 of 4729 | +300.0% | 13F |
Hedge funds, activists, holding companies and family offices we track, from their latest 13F (quarter-end value) and Form 4 filings in the last 3 years. Family offices · all institutions
CALC Institutional Ownership (13F)
Latest filings — 2026-09-30Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.
- Shares — long equity positions in this name, aggregated across share classes.
- Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
- % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
- Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.
Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.
| # | Filer | Notional Value | % of Total | Period |
|---|---|---|---|---|
| 1 | Citadel Advisors LLC Custodian | $73.95K | 100.00% | 2026-06-30 |
| # | Filer | Notional Value | % of Total | Period |
|---|---|---|---|---|
| 1 | Simplex Trading, LLC Custodian | $206 | 100.00% | 2026-06-30 |
CALC Insider Trading (Form 4)
Latest: 2026-10-05| Filed | Reporter | Role | Action | Shares | Avg Price | Net $ | Link |
|---|---|---|---|---|---|---|---|
| 2026-10-05 | Evgeny Zaytsev | Director | Grant (A) | +20,000 opt | — | EDGAR | |
| 2026-10-05 | Frederic Guerard | Director | Grant (A) | +20,000 opt | — | EDGAR | |
| 2026-10-05 | Alan Glicklich | Director | Grant (A) | +20,000 opt | — | EDGAR | |
| 2026-10-05 | Robert N Wilson | Director | Grant (A) | +20,000 opt | — | EDGAR | |
| 2026-10-05 | Allan Shaw | Director | Grant (A) | +20,000 opt | — | EDGAR | |
| 2026-09-28 | Sudarshan Hebbar | Chief Medical Officer | Grant (A) | +180,000 opt | — | EDGAR | |
| 2026-09-28 | A. Rachel Leheny | CHIEF EXECUTIVE OFFICER | Grant (A) | +360,000 opt | — | EDGAR | |
| 2026-09-28 | Kenneth A. Stauderman | Chief Scientific Officer | Grant (A) | +180,000 opt | — | EDGAR | |
| 2026-09-28 | Stephen Bardin | Chief Financial Officer | Grant (A) | +190,000 opt | — | EDGAR | |
| 2026-08-24 | ALAFI CAPITAL CO LLC | 10%+ Owner | Award (A) | — | — | EDGAR | |
| 2026-08-21 | A. Rachel Leheny | CHIEF EXECUTIVE OFFICER | Grant (A) | +373,458 RSU | — | EDGAR | |
| 2026-08-21 | Eric W Roberts | CHIEF BUSINESS OFFICER | Grant (A) | +373,458 RSU | — | EDGAR | |
| 2026-08-21 | Allan Shaw | Director | Grant (A) | +10,000 opt | — | EDGAR | |
| 2026-08-21 | Evgeny Zaytsev | Director | Grant (A) | +2,910,534 opt | — | EDGAR | |
| 2026-08-21 | Alan Glicklich | Director | Grant (A) | +10,000 opt | — | EDGAR |
CALC Insider Holdings
9 insiders · @ $1.30| # | Insider | Role | Shares | Disclosed Exposure | Lifetime OM Net | Filings | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | ALAFI CAPITAL CO LLC | 10%+ Owner | 1,022,469 | $1.33M | $0 | 1 | 2026-08-24 |
| 2 | Robert N Wilson | Director | 320,930 | $417.2K | $222.4K | 11 | 2026-10-05 |
| 3 | Fred A Middleton | Director | 196,652 | $255.6K | $2.77M | 9 | 2026-06-29 |
| 4 | Eric W Roberts | CHIEF BUSINESS OFFICER | 136,509 | $177.5K | $407.3K | 40 | 2026-08-21 |
| 5 | A. Rachel Leheny | CHIEF EXECUTIVE OFFICER | 76,777 | $99.8K | $85.1K | 22 | 2026-09-28 |
| 6 | Sudarshan Hebbar | Chief Medical Officer | 37,205 | $48.4K | $168.9K | 12 | 2026-09-28 |
| 7 | Frederic Guerard | Chief Executive Officer | 22,222 | $28.9K | $0 | 5 | 2026-10-05 |
| 8 | Stephen Bardin | Chief Financial Officer | 8,600 | $11.2K | $4.7K | 5 | 2026-09-28 |
| 9 | Kenneth A. Stauderman | Chief Scientific Officer | 2,589 | $3.4K | $2.2K | 8 | 2026-09-28 |
CALC Board & Officers
As of SEC filings through Oct 5, 2026Directors 7
- Frederic Guerard · since Sep 24, 2020
- A. Rachel Leheny · since Mar 20, 2023
- Allan Shaw · since Mar 20, 2023
- Eric W Roberts · since Mar 20, 2023
- Robert N Wilson · since Mar 20, 2023
- Alan Glicklich · since Jan 15, 2025
- Evgeny Zaytsev · since Jul 2, 2026
Officers 6
- A. Rachel Leheny · Chief Executive Officer · since Mar 20, 2023
- Michael J. Dunn · President and COO · since Mar 20, 2023
- Stephen Bardin · Chief Financial Officer · since Nov 13, 2024
- Eric W Roberts · Chief Business Officer · since Mar 20, 2023
- Kenneth A. Stauderman · Chief Scientific Officer · since Mar 20, 2023
- Sudarshan Hebbar · Chief Medical Officer · since Mar 20, 2023
10% owners 3
- Alafi Capital Co LLC (entity) · since Jun 25, 2026
- Eric W Roberts · since Mar 20, 2023
- Fred A Middleton · since Mar 20, 2023
Changes in the last 10 years (67)
| Aug 21, 2026 | A. Rachel Leheny no longer listed as a 10% owner in SEC filings |
| Jul 2, 2026 | The company announced the departure of Fred A Middleton from the board in an SEC filing |
| Jul 2, 2026 | Evgeny Zaytsev became a director |
| Jun 25, 2026 | Alafi Capital Co LLC became a 10% owner |
| Jan 15, 2025 | Alan Glicklich became a director |
| Jan 10, 2025 | The company announced the departure of Eric Bjerkholt from the board in an SEC filing |
| Nov 13, 2024 | Stephen Bardin became Chief Financial Officer |
| Apr 22, 2024 | Frederic Guerard no longer listed as Chief Executive Officer in SEC filings |
| Mar 20, 2023 | Valence Investments SPV VI, LLC became a 10% owner |
| Mar 20, 2023 | Valence Investments SPV V, LLC became a 10% owner |
| Mar 20, 2023 | Valence Investments SPV IV LLC became a 10% owner |
| Mar 20, 2023 | Sudarshan Hebbar became Chief Medical Officer |
| Mar 20, 2023 | Sanderling Ventures VII, L.P. became a 10% owner |
| Mar 20, 2023 | Sanderling Ventures VII Annex Fund, L.P. became a 10% owner |
| Mar 20, 2023 | Sanderling Ventures VII (Canada), L.P. became a 10% owner |
| Mar 20, 2023 | Sanderling Ventures Management VII became a 10% owner |
| Mar 20, 2023 | Sanderling Ventures Management VI became a 10% owner |
| Mar 20, 2023 | Sanderling Venture Partners VI LP became a 10% owner |
| Mar 20, 2023 | Sanderling Venture Partners VI Co Investment Fund LP became a 10% owner |
| Mar 20, 2023 | Sanderling VI Limited Partnership became a 10% owner |
| Mar 20, 2023 | Sanderling VI Beteiligungs GmbH & Co KG became a 10% owner |
| Mar 20, 2023 | Robert N Wilson became a director |
| Mar 20, 2023 | Michael J. Dunn became President and COO |
| Mar 20, 2023 | Kenneth A. Stauderman became Chief Scientific Officer |
| Mar 20, 2023 | Fred A Middleton became a director |
| Mar 20, 2023 | Fred A Middleton became a 10% owner |
| Mar 20, 2023 | Eric W Roberts became a director |
| Mar 20, 2023 | Eric W Roberts became a 10% owner |
| Mar 20, 2023 | Eric W Roberts became Chief Business Officer |
| Mar 20, 2023 | Daniel E. Geffken became Interim CFO |
| Mar 20, 2023 | Allan Shaw became a director |
| Mar 20, 2023 | A. Rachel Leheny became a director |
| Mar 20, 2023 | A. Rachel Leheny became a 10% owner |
| Mar 20, 2023 | A. Rachel Leheny became Chief Executive Officer |
| Apr 13, 2022 | The company announced the departure of Gerald D. Cagle from the board in an SEC filing |
| Apr 13, 2022 | Dirk Sauer became a director |
| Oct 1, 2020 | Stephen A Schwarzman reported in an SEC filing no longer being a 10% owner |
| Oct 1, 2020 | Clarus Ventures III GP, L.P. reported in an SEC filing no longer being a 10% owner |
| Oct 1, 2020 | Clarus Lifesciences III, L.P. reported in an SEC filing no longer being a 10% owner |
| Oct 1, 2020 | Blackstone Holdings II L.P. reported in an SEC filing no longer being a 10% owner |
| Oct 1, 2020 | Blackstone Holdings I/II GP L.L.C. reported in an SEC filing no longer being a 10% owner |
| Oct 1, 2020 | Blackstone Group Management L.L.C. reported in an SEC filing no longer being a 10% owner |
| Oct 1, 2020 | Blackstone Group Inc reported in an SEC filing no longer being a 10% owner |
| Oct 1, 2020 | Blackstone Clarus III L.L.C. reported in an SEC filing no longer being a 10% owner |
| Sep 24, 2020 | Stephen A Schwarzman became a 10% owner |
| Sep 24, 2020 | Robert S Breuil became Chief Financial Officer |
| Sep 24, 2020 | Parisa Zamiri became Chief Medical Officer |
| Sep 24, 2020 | Orbimed Advisors LLC became a director |
| Sep 24, 2020 | Orbimed Advisors LLC became a 10% owner |
| Sep 24, 2020 | OrbiMed Capital GP VI LLC became a director |
| Sep 24, 2020 | OrbiMed Capital GP VI LLC became a 10% owner |
| Sep 24, 2020 | Julia Marie Eastland became a director |
| Sep 24, 2020 | Hansoo Michael Keyoung became a director |
| Sep 24, 2020 | Gerald D. Cagle became a director |
| Sep 24, 2020 | Frederic Guerard became a director |
| Sep 24, 2020 | Frederic Guerard became Chief Executive Officer |
| Sep 24, 2020 | Eric Bjerkholt became a director |
| Sep 24, 2020 | Daniel Salain became Ctoo |
| Sep 24, 2020 | Clarus Ventures III GP, L.P. became a 10% owner |
| Sep 24, 2020 | Clarus Lifesciences III, L.P. became a 10% owner |
| Sep 24, 2020 | Christy L Shaffer became a director |
| Sep 24, 2020 | Christina Ackermann became a director |
| Sep 24, 2020 | Blackstone Holdings II L.P. became a 10% owner |
| Sep 24, 2020 | Blackstone Holdings I/II GP L.L.C. became a 10% owner |
| Sep 24, 2020 | Blackstone Group Management L.L.C. became a 10% owner |
| Sep 24, 2020 | Blackstone Group Inc became a 10% owner |
| Sep 24, 2020 | Blackstone Clarus III L.L.C. became a 10% owner |
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Not reported recently (23)
- Sanderling VI Limited Partnership · Last reported as a 10% owner in an SEC filing dated Nov 5, 2024
- Sanderling Venture Partners VI LP · Last reported as a 10% owner in an SEC filing dated Nov 5, 2024
- Sanderling Ventures VII, L.P. · Last reported as a 10% owner in an SEC filing dated Nov 5, 2024
- Sanderling Venture Partners VI Co Investment Fund LP · Last reported as a 10% owner in an SEC filing dated Nov 5, 2024
- Sanderling VI Beteiligungs GmbH & Co KG · Last reported as a 10% owner in an SEC filing dated Nov 5, 2024
- Sanderling Ventures VII Annex Fund, L.P. · Last reported as a 10% owner in an SEC filing dated Nov 5, 2024
- Sanderling Ventures Management VII · Last reported as a 10% owner in an SEC filing dated Nov 5, 2024
- Sanderling Ventures Management VI · Last reported as a 10% owner in an SEC filing dated Nov 5, 2024
- Sanderling Ventures VII (Canada), L.P. · Last reported as a 10% owner in an SEC filing dated Nov 5, 2024
- Daniel E. Geffken · Last reported as Interim CFO in an SEC filing dated May 20, 2024
- Valence Investments SPV V, LLC · Last reported as a 10% owner in an SEC filing dated May 3, 2023
- Valence Investments SPV VI, LLC · Last reported as a 10% owner in an SEC filing dated May 3, 2023
- Valence Investments SPV IV LLC · Last reported as a 10% owner in an SEC filing dated May 3, 2023
- Parisa Zamiri · Last reported as Chief Medical Officer in an SEC filing dated Mar 27, 2023
- Christy L Shaffer · Last reported as a director in an SEC filing dated Mar 27, 2023
- Julia Marie Eastland · Last reported as a director in an SEC filing dated Mar 27, 2023
- Robert S Breuil · Last reported as Chief Financial Officer in an SEC filing dated Mar 27, 2023
- Christina Ackermann · Last reported as a director in an SEC filing dated Mar 27, 2023
- Dirk Sauer · Last reported as a director in an SEC filing dated Mar 27, 2023
- Daniel Salain · Last reported as Ctoo in an SEC filing dated Dec 10, 2020
- Orbimed Advisors LLC · Last reported as a 10% owner in an SEC filing dated Sep 29, 2020
- OrbiMed Capital GP VI LLC · Last reported as a 10% owner in an SEC filing dated Sep 29, 2020
- Hansoo Michael Keyoung · Last reported as a director in an SEC filing dated Sep 29, 2020
| # | ETF | Provider | Weight | $ Exposure | ETF AUM | As Of |
|---|
Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.
- Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
- Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
- Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
- Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
- Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
- YoY growth — compare to the same quarter a year earlier to remove seasonality.
- Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
- Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.
TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.
Quarterly figures (12 quarters)
| Quarter | Period End | Revenue | Net Income | Diluted EPS | Op. Cash Flow |
|---|---|---|---|---|---|
| Q2 '26 | 2026-06-30 | — | $-7.65M | $-0.45 | $-4.62M |
| Q1 '26 | 2026-03-31 | — | $4.98M | $0.30 | $-4.86M |
| Q4 '25 | 2025-12-31 | — | $-10.76M | $-0.69 | $-4.85M |
| Q3 '25 | 2025-09-30 | — | $-7.80M | $-0.52 | $-4.78M |
| Q2 '25 | 2025-06-30 | — | $-5.96M | $-0.40 | $-6.67M |
| Q1 '25 | 2025-03-31 | — | $-5.04M | $-0.36 | $-4.88M |
| Q4 '24 | 2024-12-31 | — | $-4.26M | $-0.34 | $-4.97M |
| Q3 '24 | 2024-09-30 | — | $-5.62M | $-0.50 | $-4.67M |
| Q2 '24 | 2024-06-30 | — | $-3.95M | $-0.36 | $-6.79M |
| Q1 '24 | 2024-03-31 | — | $130.00K | $0.01 | $-4.71M |
| Q4 '23 | 2023-12-31 | — | $-4.15M | $-0.23 | $-3.61M |
| Q3 '23 | 2023-09-30 | — | $-4.62M | $-0.82 | $-4.57M |
Ratios derived from TTM financials and the current market price, sampled daily. History chart shows how expensive the stock is today relative to its own recent past.
- P/E — price / TTM earnings. Rough market rule: 10–15 value, 15–25 market, >30 growth/premium. Negative when earnings are negative.
- P/B — price / book value. Useful for financials and asset-heavy names; meaningless for asset-light software.
- P/S — price / TTM revenue. Useful when earnings are negative or noisy (early-stage growth).
- EV/EBITDA — capital-structure-neutral. <10 cheap, 10–15 reasonable, >20 rich. Good for comparing across leverage profiles.
- EV/Sales — like P/S but accounts for debt + cash. Compare within sector.
- ROE — return on equity. >15% strong, >25% exceptional. Caution: high leverage inflates ROE.
- ROA — return on assets. Leverage-neutral; >5% solid, >10% exceptional.
- Div Yield — annual dividend / price. Compare to 10Y Treasury; sustained yield >6% often signals distress.
- FCF Yield — free cash flow / market cap. >5% is attractive; negative means burning cash.
- Debt/Equity — leverage. <1 conservative, >2 aggressive. Sector-dependent (utilities naturally high, tech low).
- Current Ratio — short-term liquidity. >1.5 comfortable, <1 raises short-term solvency flags.
- Compare current level to the 3-year band: near the high end = relatively expensive; near the low = relatively cheap.
- Multiples expanding while earnings are flat = sentiment-driven rally.
- Multiples compressing while earnings grow = value coming from fundamentals.
Regulatory short-interest reports publish on a bi-weekly settlement cadence; short-volume is reported daily by the trade-reporting facilities. Float is derived from insider-ownership filings.
- Short Interest — total shares currently sold short as of the settlement date. Lags real time by ~8 business days.
- SI % of Float — short interest / free float. The key crowding metric.
- Days to Cover — short interest / avg daily volume. How many full trading days it would take shorts to buy back. High DTC + catalyst = squeeze fuel.
- Short Vol Ratio — today's short-sale volume / total volume. Intraday selling pressure proxy (not the same as short interest).
- Free Float — shares available for public trading (total shares minus insider / restricted).
- Float % — free float / shares outstanding. <50% = tightly held, more prone to squeezes.
- SI % of Float < 5% — typical, no particular signal.
- 5–15% — elevated; watch for catalysts (earnings, guidance, macro).
- 15–30% — heavily shorted; tight-float names in this range have produced notable squeezes historically.
- >30% — extreme; borrow is likely expensive and squeeze risk is material.
- Days to Cover > 5 combined with high SI% amplifies squeeze potential.
- Trend matters more than level. Rapidly rising short interest often precedes negative catalysts or heavy hedging.
- A sudden drop in SI after a rally may indicate a squeeze in progress.
Short interest is reported mid-month and end-of-month; short volume is daily.