Alexis Borisy

CIK 1319446 · Executive Chairman · last filed 2026-06-23

"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.

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Disclosed Exposure

$512.46M

Companies

12

Total Filings

71

Lifetime Open-Market Net

-$25.83M

Filer Profile

Reported Address
C/O COMBINATORX, INCORPORATED
245 FIRST STREET, 16TH FLOOR
CAMBRIDGE, MA 02142
Related Filers
OPKO HEALTH, INC. — 5 joint filings, latest 2023-06-23
Tango Therapeutics, Inc. — 5 joint filings, latest 2025-06-09
Profile details as reported on the filer's SEC submissions — for individual insiders the address is often in care of the issuer. Related filers are identified from jointly filed SEC submissions and shared reported addresses. View filings on SEC EDGAR.

Holdings By Company

Latest on-record share count from this person's most recent non-derivative Form 4 transaction in each company. Disclosed exposure = shares × current underlying price.
Symbol Role Shares Price Disclosed Exposure Lifetime OM Net Filings Latest Filed
RVMD Director 2,340,075 $203.77 $476.84M $0 6 2026-06-23
PBLS Director 105,414 $36.88 $3.89M $0 2 2026-06-15
RLAY Director 234,175 $18.87 $4.42M $0 10 2026-06-10
Blueprint Medicines Corp (BPMC) Delisted Director 74,160 $129.46 $9.60M -$2.01M 18 2025-07-21
RVMDW Director 2,338,884 $11.29 $26.41M $0 3 2025-06-30
TNGX Director 17,500 $23.78 $416.1K $0 4 2025-06-09
EQRx, Inc. (EQRXW) Delisted Executive Chairman 0 $0.05 $0 $0 3 2023-11-09
OPK Director 312,612 $1.57 $490.8K $0 4 2023-06-23
Dianthus Therapeutics, Inc. /DE/ (MGTA) Delisted Director 256 $11.19 $2.9K $0 5 2021-09-23
Foundation Medicine, Inc. (FMI) Delisted Director 6,642,818 -$23.82M 7 2017-06-22
EDIT Director 0 $2.70 $0 $0 2 2017-06-19
EPIRUS Biopharmaceuticals, Inc. (CRXX) Delisted CEO & President 312,204 -$3.3K 6 2009-01-28

Recent Filings · Page 7 of 8

71 filings
Insider activity across all companies, newest first. Form 4 rows are post-trade confirmations (buys, sells, grants, exercises). Notice (144) rows are pre-trade notices of intent to sell restricted or control stock under Rule 144 — they may not all execute. Compare adjacent dates to see which notices became actual sales.
Filed Symbol Action Net Shares Net $ Link
2015-06-22 Foundation Medicine, Inc. (FMI) Delisted Grant (A) +5,997 $193.3K EDGAR
2015-05-15 Foundation Medicine, Inc. (FMI) Delisted Other (J) +448 $0 EDGAR
2015-04-16 Foundation Medicine, Inc. (FMI) Delisted Sell (S) −241,768 -$12.09M EDGAR
2015-04-09 Foundation Medicine, Inc. (FMI) Delisted Sell (S) −234,542 -$11.73M EDGAR
2013-10-02 Foundation Medicine, Inc. (FMI) Delisted Conv (C) +6,219,645 $0 EDGAR
2009-01-28 EPIRUS Biopharmaceuticals, Inc. (CRXX) Delisted Sell (S) −5,256 -$3.3K EDGAR
2008-07-17 EPIRUS Biopharmaceuticals, Inc. (CRXX) Delisted Grant (A) $0 EDGAR
2008-01-29 EPIRUS Biopharmaceuticals, Inc. (CRXX) Delisted Tax (F) −3,969 -$20.4K EDGAR
2008-01-17 EPIRUS Biopharmaceuticals, Inc. (CRXX) Delisted Grant (A) $0 EDGAR
2007-07-13 EPIRUS Biopharmaceuticals, Inc. (CRXX) Delisted Grant (A) $0 EDGAR
Showing 6170 of 71
Page 7 of 8
Form 4 codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (see filing footnote). Only P / S codes carry directional signal.
Notice (144 / 144/A): Form 144 is a notice of intent to sell restricted/control stock under Rule 144, filed before the sale; 144/A is an amendment. Many notices are pre-scheduled under Rule 10b5-1 plans. A Form 4 with code S typically follows within a few days when the planned sale executes; missing follow-up Form 4s suggest the notice was cancelled or modified.