James N Topper

CIK 1341382 · last filed 2026-05-21

"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.

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Disclosed Exposure

$907.23M

Companies

17

Total Filings

114

Lifetime Open-Market Net

$281.48M

Holdings By Company

Latest on-record share count from this person's most recent non-derivative Form 4 transaction in each company. Disclosed exposure = shares × current underlying price.
Symbol Role Shares Price Disclosed Exposure Lifetime OM Net Filings Latest Filed
PHAT Director 126,121 $10.37 $1.31M $100.19M 10 2026-05-21
NAMSW Director 3,801,000 $18.80 $71.46M $586.2K 8 2025-09-17
MBX 10%+ Owner 4,552,774 $35.51 $161.67M $40.00M 1 2024-09-17
ALPINE IMMUNE SCIENCES, INC. (ALPN) Delisted Director 1,371,450 $64.97 $89.10M $2.00M 13 2024-05-20
HilleVax, Inc. (HLVX) Delisted 10%+ Owner 8,544,187 $2.09 $17.86M $641.6K 1 2024-04-08
ANAB Director 280,341 $56.07 $15.72M $6.00M 10 2023-01-10
Allena Pharmaceuticals, Inc. (ALNA) Delisted Director 1,466,805 $0.07 $110.0K $7.00M 4 2020-11-18
Aptinyx Inc. (APTX) Delisted Director 3,195,055 $0.06 $194.9K $2.40M 7 2020-04-02
PASG 10%+ Owner 2,977,242 $5.81 $17.30M $39.60M 1 2020-03-03
MIRM 10%+ Owner 3,116,912 $99.34 $309.65M $27.00M 1 2019-07-24
Entasis Therapeutics Holdings Inc. (ETTX) Delisted Director 337,707 $2.19 $739.6K $5.64M 2 2019-01-22
Sierra Oncology, Inc. (SRRA) Delisted Director 5,925,926 $54.99 $325.87M $8.00M 1 2017-02-16
Sierra Oncology, Inc. (DNAI) Delisted Director 1,966,195 $3.74M 2 2016-06-20
GKOS 10%+ Owner 2,603,362 $126.81 $330.13M $0 1 2015-06-30
AMICUS THERAPEUTICS, INC. (FOLD) Delisted Director 907,464 $14.49 $13.15M $34.05M 46 2013-06-17
PORTOLA PHARMACEUTICALS INC (PTLA) Delisted Director 7,252 $0 2 2013-06-07
LA JOLLA PHARMACEUTICAL CO (LJPC) Delisted Director 4,210,711 $6.22 $26.19M $4.63M 4 2009-02-26

Recent Filings · Page 4 of 12

114 filings
Form 4 transactions across all companies, newest first.
Filed Symbol Action Net Shares Net $ Link
2020-11-18 Allena Pharmaceuticals, Inc. (ALNA) Delisted Grant (A) $0 EDGAR
2020-05-22 PHAT Grant (A) $0 EDGAR
2020-04-02 Aptinyx Inc. (APTX) Delisted Grant (A) +4,976 $10.7K EDGAR
2020-03-03 PASG Mixed +20,036,876 $39.60M EDGAR
2020-02-13 ANAB Grant (A) $0 EDGAR
2020-01-06 ALPINE IMMUNE SCIENCES, INC. (ALPN) Delisted Grant (A) $0 EDGAR
2020-01-03 Aptinyx Inc. (APTX) Delisted Grant (A) $0 EDGAR
2019-10-30 PHAT Mixed +12,031,355 $202.88M EDGAR
2019-10-02 Aptinyx Inc. (APTX) Delisted Grant (A) $0 EDGAR
2019-07-24 MIRM Mixed +14,267,648 $27.00M EDGAR
Showing 3140 of 114
Page 4 of 12
Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (see filing footnote). Only P / S codes carry directional signal.