RA CAPITAL MANAGEMENT, L.P.
CIK 1346824 · last filed 2026-08-26
RA CAPITAL MANAGEMENT, L.P. is a corporate insider who has filed 102 SEC Form 4 insider transactions across 45 companies since 2007. The most recent filing shows the insider exercised options covering $22.4K of VOR on Aug 26, 2026. Across all open-market trades the lifetime net is −$102.39B, making them a net seller over the disclosed history. Current disclosed insider exposure totals $1.12B across reported positions. The firm reports its address in Boston, MA. 480 SEC filings were submitted jointly with Peter Kolchinsky.
"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.
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Disclosed Exposure
$1.12B
Companies
45
Total Filings
102
Lifetime Open-Market Net
-$102.39B
Filer Profile
Reported Address
200 BERKELEY STREET, 18TH FLOORBOSTON, MA 02116
Phone
(617) 778-2500
State of Incorporation
DE
Formerly Known As
RA CAPITAL MANAGEMENT, LLC (2005–2019)
Related Filers
Peter Kolchinsky — 480 joint filings, latest 2026-08-26
RA Capital Healthcare Fund LP — 461 joint filings, latest 2026-08-26
Rajeev M. Shah — 354 joint filings, latest 2026-08-26
RA Capital Nexus Fund II, L.P. — 97 joint filings, latest 2026-07-22
RA Capital Nexus Fund, L.P. — 86 joint filings, latest 2026-07-31
RA Capital Nexus Fund III, L.P. — 57 joint filings, latest 2026-08-14
RA Capital Healthcare Fund II, L.P. — 42 joint filings, latest 2009-05-11
RICHARD ALDRICH — 36 joint filings, latest 2008-11-21
Profile details as reported on the filer's SEC submissions — for individual insiders the address is often in care of the issuer. Related filers are identified from jointly filed SEC submissions and shared reported addresses.
View filings on SEC EDGAR.
Holdings By Company
Latest on-record share count from this person's most recent non-derivative Form 4 transaction in each company. Disclosed exposure = shares × current underlying price.
| Symbol | Role | Shares | Price | Disclosed Exposure | Lifetime OM Net | Filings | Latest Filed |
|---|---|---|---|---|---|---|---|
| VOR | Director | 1,500 | $22.30 | $33.5K | $214.53M | 5 | 2026-08-26 |
| FRNM | Director | 908,103 | — | — | $0 | 1 | 2026-07-22 |
| HOWL | Director | 303,719 | $0.98 | $298.3K | -$583.7K | 3 | 2026-06-22 |
| SION | Director | 661,019 | $7.85 | $5.19M | $114.30M | 3 | 2026-06-18 |
| NKTX | Director | 2,271,796 | $2.91 | $6.61M | $180.00M | 2 | 2026-06-11 |
| BCAX | Director | — | $22.81 | — | $0 | 1 | 2026-06-10 |
| COAG | 10%+ Owner | 6,375,972 | $39.40 | $251.21M | $479.1K | 1 | 2026-05-21 |
| ACET | 10%+ Owner | 1,033,605 | $9.52 | $9.84M | $6.42M | 1 | 2026-04-13 |
| WVE | Director | 23,157,567 | $4.59 | $106.29M | $328.50M | 5 | 2026-03-30 |
| Climb Bio, Inc. (ELYM) Delisted | Director | 2,866,375 | $5.11 | $14.65M | $174.2K | 1 | 2026-01-07 |
| MLYS | Director | 1,867,229 | $28.20 | $52.66M | $150.00M | 3 | 2025-09-08 |
| SEPN | Director | — | $38.51 | — | $0 | 1 | 2025-06-20 |
| Cidara Therapeutics, Inc. (CDTX) Delisted | Director | — | $221.38 | — | $0 | 1 | 2025-06-18 |
| TYRA | Director | 442,721 | $22.03 | $9.75M | $9.52M | 2 | 2025-06-11 |
| SLDB | Director | 4,192,216 | $8.70 | $36.47M | $25.00M | 3 | 2025-02-21 |
| ANTX | 10%+ Owner | 1,725,348 | $5.41 | $9.33M | $105.98M | 3 | 2024-08-13 |
| SPRY | Director | 2,106,774 | $4.76 | $10.03M | $0 | 2 | 2024-06-24 |
| ABOS | Director | — | $2.92 | — | $0 | 3 | 2024-06-10 |
| BOLD | 10%+ Owner | 1,587,912 | $2.83 | $4.49M | $25.00M | 1 | 2024-04-04 |
| Icosavax, Inc. (ICVX) Delisted | Director | — | $15.31 | — | $0 | 1 | 2023-06-08 |
| DICE | Director | 786,407 | $24.83 | $19.53M | $141.28M | 3 | 2023-03-30 |
| Enliven Therapeutics, Inc. (IMRA) Delisted | 10%+ Owner | 970,005 | $14.59 | $14.15M | $10.06M | 1 | 2023-01-05 |
| FULC | 10%+ Owner | 7,824,600 | $3.80 | $29.73M | $52.30M | 1 | 2022-12-16 |
| JANX | Director | — | $17.10 | — | $0 | 1 | 2022-06-16 |
| iTeos Therapeutics, Inc. (ITOS) Delisted | Director | 3,155,667 | $10.15 | $32.03M | $0 | 2 | 2022-06-10 |
| Forma Therapeutics Holdings, Inc. (FMTX) Delisted | Director | 1,511,425 | $20.01 | $30.24M | $0 | 1 | 2022-06-09 |
| KALA | Director | 2,819 | $0.57 | $1.6K | $16.58M | 4 | 2022-05-26 |
| PEPG | Director | 1,052,851 | $2.98 | $3.14M | $193.75M | 2 | 2022-05-12 |
| Satsuma Pharmaceuticals, Inc. (STSA) Delisted | Director | 4,681,858 | $1.10 | $5.15M | $60.00M | 2 | 2020-12-07 |
| RYTM | 4,568,464 | $104.71 | $478.36M | -$28.12M | 1 | 2020-12-04 | |
| PMVP | 10%+ Owner | 1,710,265 | $1.40 | $2.39M | $51.30M | 1 | 2020-09-29 |
| VSTM | 10%+ Owner | 1,345,171 | $7.32 | $9.85M | -$8.88M | 1 | 2020-06-29 |
| PHAT | 10%+ Owner | 3,707,408 | $8.36 | $30.99M | $5.96M | 1 | 2020-03-31 |
| THOR | 10%+ Owner | 0 | $26.17 | $0 | $100.00M | 2 | 2020-01-24 |
| Ra Pharmaceuticals, Inc. (RARX) Delisted | Director | 4,858,260 | — | — | $98.10M | 5 | 2019-06-13 |
| ARVN | 3,138,412 | $8.45 | $26.52M | $48.00M | 1 | 2018-10-03 | |
| KalVista Pharmaceuticals, Inc. (KALV) Delisted | Director | 591,070 | $27.00 | $15.96M | $0 | 1 | 2016-11-23 |
| ACRS | 10%+ Owner | 2,469,552 | $5.32 | $13.14M | $59.06M | 3 | 2015-10-30 |
| SANGAMO THERAPEUTICS, INC (SGMO) Delisted | 2,829,441 | $0.18 | $502.5K | -$82.39M | 2 | 2015-02-18 | |
| ACHILLION PHARMACEUTICALS INC (ACHN) Delisted | 10%+ Owner | 9,700,000 | — | — | -$104.29B | 8 | 2014-09-26 |
| DERMA SCIENCES, INC. (DSCI) Delisted | 1,884,876 | — | — | -$10.65M | 1 | 2014-01-13 | |
| BIOSPECIFICS TECHNOLOGIES CORP (BSTC) Delisted | 10%+ Owner | 626,462 | — | — | -$3.54M | 6 | 2010-02-26 |
| SEQUENOM INC (SQNM) Delisted | 10%+ Owner | 5,506,093 | — | — | $28.98M | 3 | 2008-07-15 |
| LIPID SCIENCES INC/ (LIPD) Delisted | 10%+ Owner | 3,705,312 | — | — | -$56.2K | 1 | 2008-03-31 |
| ARADIGM CORP (ARDM) Delisted | 10%+ Owner | 187,245 | — | — | $5.21M | 2 | 2007-11-05 |
Recent Filings
102 filingsInsider activity across all companies, newest first. Form 4 rows are post-trade confirmations (buys, sells, grants, exercises). Notice (144) rows are pre-trade notices of intent to sell restricted or control stock under Rule 144 — they may not all execute. Compare adjacent dates to see which notices became actual sales.
| Filed | Symbol | Action | Net Shares | Net $ | Link |
|---|---|---|---|---|---|
| 2026-08-26 | VOR | Exer (M) | +6,000 | $22.4K | EDGAR |
| 2026-07-22 | FRNM | Grant (A) | +102,320,890 | $367.88M | EDGAR |
| 2026-06-22 | HOWL | Sell (S) | −1,667,644 | -$583.7K | EDGAR |
| 2026-06-18 | SION | Grant (A) | — | $0 | EDGAR |
| 2026-06-11 | NKTX | Grant (A) | — | $0 | EDGAR |
| 2026-06-10 | BCAX | Grant (A) | — | $0 | EDGAR |
| 2026-05-21 | COAG | Buy (P) | +19,192 | $479.1K | EDGAR |
| 2026-04-13 | ACET | Buy (P) | +894,384 | $6.42M | EDGAR |
| 2026-03-30 | WVE | Buy (P) | +35,089,984 | $218.50M | EDGAR |
| 2026-01-09 | — | Mixed | −13,462,092 | -$4.12B |
Showing 1–10 of 102
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Form 4 codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (see filing footnote). Only P / S codes carry directional signal.
Notice (144 / 144/A): Form 144 is a notice of intent to sell restricted/control stock under Rule 144, filed before the sale; 144/A is an amendment. Many notices are pre-scheduled under Rule 10b5-1 plans. A Form 4 with code S typically follows within a few days when the planned sale executes; missing follow-up Form 4s suggest the notice was cancelled or modified.
Notice (144 / 144/A): Form 144 is a notice of intent to sell restricted/control stock under Rule 144, filed before the sale; 144/A is an amendment. Many notices are pre-scheduled under Rule 10b5-1 plans. A Form 4 with code S typically follows within a few days when the planned sale executes; missing follow-up Form 4s suggest the notice was cancelled or modified.