EcoR1 Capital, LLC

CIK 1587114 · last filed 2026-05-11

EcoR1 Capital, LLC is a corporate insider who has filed 43 SEC Form 4 insider transactions across 16 companies since 2014. The most recent filing shows the insider bought $4.7M of ATRA on May 11, 2026. Across all open-market trades the lifetime net is +$269.0M, making them a net buyer over the disclosed history. Current disclosed insider exposure totals $1.36B across reported positions. The firm reports its address in San Francisco, CA. 28 SEC filings were submitted jointly with OLEG NODELMAN.

"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.

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Disclosed Exposure

$1.36B

Companies

16

Total Filings

43

Lifetime Open-Market Net

$269.05M

Filer Profile

Reported Address
357 TEHAMA STREET #3
SAN FRANCISCO, CA 94103
Phone
(415) 448-6534
State of Incorporation
DE
Related Filers
OLEG NODELMAN — 28 joint filings, latest 2026-01-12
ANAPTYSBIO, INC — 15 joint filings, latest 2025-01-02
EcoR1 Capital Fund Qualified, L.P. — 12 joint filings, latest 2023-09-22
Biotech Opportunity GP, LLC — 10 joint filings, latest 2023-09-22
EcoR1 Venture Opportunity Fund, LP — 10 joint filings, latest 2023-09-22
Xencor Inc — 7 joint filings, latest 2026-05-15
Tango Therapeutics, Inc. — 6 joint filings, latest 2026-02-17
EcoR1 Panacea Holdings, LLC — 4 joint filings, latest 2021-04-13
Profile details as reported on the filer's SEC submissions — for individual insiders the address is often in care of the issuer. Related filers are identified from jointly filed SEC submissions and shared reported addresses. View filings on SEC EDGAR.

Holdings By Company

Latest on-record share count from this person's most recent non-derivative Form 4 transaction in each company. Disclosed exposure = shares × current underlying price.
Symbol Role Shares Price Disclosed Exposure Lifetime OM Net Filings Latest Filed
ATRA 10%+ Owner 1,552,000 $9.38 $14.56M $4.74M 1 2026-05-11
TRAX 10%+ Owner 3,174,519 $36.44 $115.68M $65.00M 1 2026-04-22
Adaptimmune Therapeutics PLC (ADAP) Delisted 10%+ Owner 127,805,220 $0.06 $7.40M -$6.89M 1 2025-07-30
iTeos Therapeutics, Inc. (ITOS) Delisted 10%+ Owner 7,388,978 $10.15 $75.00M $38.69M 1 2025-05-16
PRTA 10%+ Owner 8,266,342 $8.93 $73.82M -$5.40M 10 2025-05-06
ZYME Director 15,720,161 $26.24 $412.50M $81.32M 13 2025-01-21
ANAB Director 7,880,094 $53.87 $424.50M $92.83M 6 2025-01-02
Mersana Therapeutics, Inc. (MRSN) Delisted 10%+ Owner 453,120 $29.08 $13.18M $0 1 2024-12-23
TNGX 10%+ Owner 11,836,178 $23.78 $281.46M -$8.44M 1 2024-11-08
VYGR 10%+ Owner 3,961,507 $3.19 $12.64M -$4.48M 2 2023-01-11
Odonate Therapeutics, Inc. (ODT) Delisted 10%+ Owner 545,000 $1.12 $610.4K -$9.43M 1 2021-12-10
CRVS 10%+ Owner 2,081,077 $12.91 $26.87M -$25.06M 1 2021-10-01
Surface Oncology, Inc. (SURF) Delisted 10%+ Owner 4,701,081 $1.07 $5.03M -$2.38M 1 2020-09-03
Nuvation Bio Inc. (PANA.U) Delisted Director 390,000 $27.30M 1 2020-07-06
Akouos, Inc. (AKUS) Delisted 10%+ Owner 1,975,984 $13.29 $26.26M $19.99M 1 2020-07-02
GENVEC INC (GNVC) Delisted 10%+ Owner 111,767 $1.25M 1 2014-03-28

Recent Filings

43 filings
Insider activity across all companies, newest first. Form 4 rows are post-trade confirmations (buys, sells, grants, exercises). Notice (144) rows are pre-trade notices of intent to sell restricted or control stock under Rule 144 — they may not all execute. Compare adjacent dates to see which notices became actual sales.
Filed Symbol Action Net Shares Net $ Link
2026-05-11 ATRA Buy (P) +507,407 $4.74M EDGAR
2026-04-22 TRAX Sell (S) +4,705,575 $65.00M EDGAR
2025-07-30 Adaptimmune Therapeutics PLC (ADAP) Delisted Sell (S) −64,052,538 -$6.89M EDGAR
2025-05-16 iTeos Therapeutics, Inc. (ITOS) Delisted Buy (P) +4,958,978 $38.69M EDGAR
2025-05-06 PRTA Sell (S) −6,279,684 -$50.84M EDGAR
2025-01-21 ZYME Buy (P) +141,429 $1.96M EDGAR
2025-01-15 ZYME Buy (P) +167,654 $2.28M EDGAR
2025-01-10 ZYME Buy (P) +225,119 $2.97M EDGAR
2025-01-02 ANAB Buy (P) +170,196 $2.20M EDGAR
2025-01-02 ZYME Buy (P) +363,369 $5.32M EDGAR
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Form 4 codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (see filing footnote). Only P / S codes carry directional signal.
Notice (144 / 144/A): Form 144 is a notice of intent to sell restricted/control stock under Rule 144, filed before the sale; 144/A is an amendment. Many notices are pre-scheduled under Rule 10b5-1 plans. A Form 4 with code S typically follows within a few days when the planned sale executes; missing follow-up Form 4s suggest the notice was cancelled or modified.