Karen L. Smith

CIK 1639637 · Chief Medical Officer · last filed 2026-04-02

"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.

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Disclosed Exposure

$7.06M

Companies

12

Total Filings

54

Lifetime Open-Market Net

-$2.68M

Holdings By Company

Latest on-record share count from this person's most recent non-derivative Form 4 transaction in each company. Disclosed exposure = shares × current underlying price.
Symbol Role Shares Price Disclosed Exposure Lifetime OM Net Filings Latest Filed
SKYE Director $0.79 $0 5 2026-04-02
SANGAMO THERAPEUTICS, INC (SGMO) Delisted Director 102,100 $0.18 $18.1K $0 9 2025-06-16
CNTX Director $1.39 $0 2 2025-06-12
AUPH Director 24,807 $15.82 $392.4K -$44.2K 3 2024-11-25
Tourmaline Bio, Inc. (TALS) Delisted Director $27.20 $0 3 2023-06-14
QNCX Chief Medical Officer $0.93 $0 1 2023-02-02
Quince Therapeutics, Inc. (CRTX) Delisted Chief Medical Officer 194,690 $1.95 $379.6K $0 2 2022-05-27
ACCELERON PHARMA INC (XLRN) Delisted Director 0 $178.75 $0 -$2.88M 8 2021-11-22
ANTARES PHARMA, INC. (ATRS) Delisted Director 79,645 $5.59 $445.2K $0 4 2021-06-14
EBS EVP, Chief Medical Officer 11,888 $8.32 $98.9K $0 2 2021-05-11
JAZZ EVP, R&D and CMO 28,474 $230.56 $6.56M $250.0K 13 2018-03-07
Sucampo Pharmaceuticals, Inc. (SCMP) Delisted Director $0 1 2018-02-13

Recent Filings · Page 2 of 6

54 filings
Form 4 transactions across all companies, newest first.
Filed Symbol Action Net Shares Net $ Link
2024-06-06 SANGAMO THERAPEUTICS, INC (SGMO) Delisted Grant (A) +25,000 $0 EDGAR
2023-08-21 AUPH Grant (A) $0 EDGAR
2023-06-14 Tourmaline Bio, Inc. (TALS) Delisted Grant (A) $0 EDGAR
2023-06-05 SANGAMO THERAPEUTICS, INC (SGMO) Delisted Grant (A) +13,900 $0 EDGAR
2023-02-02 QNCX Grant (A) $0 EDGAR
2022-06-13 Tourmaline Bio, Inc. (TALS) Delisted Grant (A) $0 EDGAR
2022-05-27 Quince Therapeutics, Inc. (CRTX) Delisted Grant (A) +170,354 $0 EDGAR
2022-05-26 Disp (D) −79,645 -$446.0K
2022-05-23 Quince Therapeutics, Inc. (CRTX) Delisted Grant (A) +24,336 $0 EDGAR
2022-05-17 Tourmaline Bio, Inc. (TALS) Delisted Grant (A) $0 EDGAR
Showing 1120 of 54
Page 2 of 6
Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (see filing footnote). Only P / S codes carry directional signal.