APVO Aptevo Therapeutics Inc
XNASStock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership. Iron condor setups Fibonacci levels Insider trading
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- Industry (SIC)
- PHARMACEUTICAL PREPARATIONS (2834) · industry map
- Exchange
- XNAS
- Market Cap
- $0.0B
- Employees
- 33
- List Date
- 2016-07-20
- CIK
- 0001671584
- Next Earnings
- 2026-11-05
- EPS Forecast
- ($3.72) (2 est.)
- Headquarters
- Seattle, WA
- Homepage
- https://www.aptevotherapeutics.com
Aptevo Therapeutics Inc is a clinical-stage research and development biotechnology company focused on developing novel immunotherapeutic candidates for the treatment of different forms of cancer. Its clinical candidates are; ALG.APV-527, which targets co-stimulatory receptors and tumor antigens, and CD3xCD123, which is being developed as a potential treatment of frontline acute myelogenous leukemia. The company's preclinical candidates, APVO711, CD3xCD123, APVO0442, and APVO603, are being developed using the ADAPTIR modular protein technology platform. The company's versatile and robust ADAPTI…
Each spoke is this symbol's rank within its sector (0–100; the dotted ring marks the sector median at 50). Higher is more constructive for a long. One spoke — News sentiment — is an absolute reading, not a sector rank. Grayed spokes have no data. A fuller shape is a summary, not a recommendation.
| Month | '21 | '22 | '23 | '24 | '25 | '26 | Avg |
|---|---|---|---|---|---|---|---|
| Jan | -9.90% | -30.64% | 0.44% | -8.65% | -4.16% | -22.58% | -12.58% |
| Feb | -2.65% | -4.00% | -3.64% | 11.11% | -12.18% | -2.92% | -2.38% |
| Mar | -6.09% | 5.96% | -3.10% | -35.01% | -62.46% | -39.77% | -23.41% |
| Apr | -5.65% | -32.38% | -7.69% | -83.28% | -46.90% | 16.31% | -26.60% |
| May | -1.14% | 2.23% | -13.81% | -25.77% | -52.71% | -0.20% | -15.23% |
| Jun | -14.23% | -20.80% | -7.01% | -61.17% | -36.06% | -15.27% | -25.76% |
| Jul | -15.30% | 10.06% | -26.83% | 20.75% | -5.42% | -6.16% | -3.82% |
| Aug | -2.13% | -9.58% | -55.10% | -10.29% | -38.81% | -38.23% | -25.69% |
| Sep | -15.81% | -15.32% | -22.72% | -48.26% | -9.37% | -22.22% | -22.28% |
| Oct | -2.68% | 3.78% | -17.74% | 60.62% | 11.51% | -14.77%* | 6.79% |
| Nov | -43.05% | 3.65% | -35.29% | 12.94% | -6.12% | -- | -13.57% |
| Dec | -0.76% | -24.92% | -4.69% | -50.93% | -60.31% | -- | -28.32% |
| Total | -74.70% | -73.71% | -91.06% | -98.41% | -98.89% | -82.89% | -86.61% |
Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.
- SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
- EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
- MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
- ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
- +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
- RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
- Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
- Williams %R — inverted scale: <−80 oversold, >−20 overbought.
Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.
- Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
- OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
- Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
- ATR / True Range — average daily $ move; sizing and stop-loss reference.
- HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.
Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →
Trend Indicators
Momentum Oscillators
Volume & Volatility
Data Summary
LLM Stock Analysis Report: APVO
Executive Summary
BULLISH/BEARISH: BEARISH (Confidence Level: 6/10)
Key drivers:
- Bearish technical signals from MACD and trend indicators
- High volatility and beta relative to market
Primary risks:
- Potential for further price decline due to bearish momentum
- Elevated risk due to high volatility and beta
Investment thesis:
APVO is experiencing a bearish trend with strong downward momentum, driven by negative news sentiment and technical indicators. While the stock has potential for a bounce or correction, the overall bearish sentiment suggests caution.
Recent news sentiment impact:
The recent news headlines are mixed, but the majority lean towards neutral to positive sentiment. However, this does not outweigh the bearish technical signals and market volatility.
Technical Analysis
Trend Direction:
- Short-term (1-4 weeks): BEARISH
- Medium-term (1-3 months): NEUTRAL
- Long-term (3-12 months): BULLISH
Support/Resistance Levels:
- Key levels to monitor: $4.52 (lower BB), $4.87 (SMA 20), and $5.21 (upper BB)
Momentum Signals:
- RSI interpretation: NEUTRAL (48.80)
- MACD signal: BEARISH (histogram -0.03)
- Bollinger Bands position: NEUTRAL
Volume Analysis:
- Volume trends: Decreasing volume on recent price decline
- Institutional interest signals: No unusual activity or institutional buying/selling observed
News & Sentiment Analysis
Recent Headlines Summary:
The majority of recent news headlines are neutral to positive, with a few negative mentions. However, this does not contradict the bearish technical signals and market volatility.
Sentiment Assessment:
- Aggregate sentiment: NEUTRAL
- Recent news sentiment impact: BEARISH (4/6)
Catalyst Identification:
No significant catalysts or events on the horizon that could significantly impact the stock price.
Market Narrative:
The bearish technical signals and market volatility suggest a cautious approach, while the recent positive news headlines may provide some support for the stock. However, the overall sentiment remains neutral to negative.
Risk & Volatility Assessment
Beta Interpretation:
- Beta relative to SPY (market): 1.52 (high risk)
Volatility Regime:
- Current volatility: High
- Historical volatility: HV20 64.7%, HV30 60.4%
Options Market Signals:
- IV rank: N/A
- Put/call ratios: N/A
- Unusual activity: None
Downside Protection:
- Support levels to monitor: $4.52 (lower BB) and $4.87 (SMA 20)
Market Context & Positioning
Sector Performance:
- Relative strength vs sector/market: NEUTRAL
Institutional Activity:
- No unusual institutional buying/selling activity observed
Correlation Analysis:
- R-squared interpretation: WEAK CORRELATION (-0.14) with market
Relative Valuation:
- Position within trading range: NEAR THE BOTTOM OF THE TRADING RANGE
Key Levels & Action Items
Critical Price Levels:
- Support levels to monitor: $4.52 (lower BB), $4.87 (SMA 20)
- Resistance level to watch: $5.21 (upper BB)
Breakout/Breakdown Levels:
- Breakout above SMA 20 or upper BB could indicate a potential reversal
- Breakdown below lower BB could confirm bearish momentum
Time-Sensitive Catalysts:
No time-sensitive catalysts or events on the horizon that could significantly impact the stock price.
Risk Management:
- Stop-loss levels: Consider setting stop-loss at $4.52 (lower BB) to limit potential losses
- Position sizing considerations: Consider reducing position size due to high volatility and beta
| Earnings Date | Timing | Expected Move | Actual Move | Ratio | Outcome |
|---|---|---|---|---|---|
| 2026-08-17 | unknown | — | 3.20% | — | Within |
Earnings calendar: this week’s reports with expected vs actual moves →
APVO Options Activity & IV Rank
Each spread is ranked by a composite score built in three stages. Full documentation →
score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.
RR and BF (30-delta) from the persisted per-symbol skew snapshot — wing strikes picked by real greeks.delta, not a moneyness proxy. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.
- RSI <40 bullish / >60 bearish
- MACD crossover + histogram trend
- Price vs SMA 50 & SMA 200
- Stochastic %K <20 / >80
- Williams %R <−80 / >−20
- Blended ATR + straddle expected-move penalty
- Bollinger Band signal (+ counter-trend penalty)
- BB width — vol contraction boost for ICs
- IV rank ≥ 75 → strong boost for credit spreads
- IV rank < 25 → penalty (selling cheap vol)
- Min open interest across all legs
- OI < 100 → −0.10 · OI < 500 → −0.05
score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →
Enter a ticker to scan for optimal spread opportunities.
Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.
IV(put wing) − IV(ATM), in vol pointsHow much the OTM put trades above (or below) the at-the-money strike. Measures the height of the put-side tail relative to ATM — i.e. how expensive crash insurance is on this name.
- Positive (typical) — wing IV > ATM IV. Standard equity put skew: portfolios bid up crash protection, so OTM puts trade richer than ATM.
- Near zero or negative (unusual) — wing IV ≤ ATM IV. Flat or inverted put side. Common when there's no fear demand, in tightly mean-reverting names, or right after an earnings catalyst clears.
- Percentile vs own 3-yr history: high = wings rich (good time to sell wing premium); low = wings cheap (good time to buy protection).
- Not directional — high or low wings don't predict up or down moves. It's a price tag on tail insurance, not a forecast.
IV(call wing) − IV(put wing), equal delta on each sideWhich side of the smile is the market paying up for? Measures the tilt of the surface — call skew vs put skew at matched deltas.
- Negative (typical) — puts richer than calls. Standard equity behavior: hedging demand makes puts carry a premium. Most large-caps sit in the −1 to −5 vol-point range.
- Strongly negative (< −5 pts) — heavy downside hedging, elevated fear, or an upcoming catalyst (earnings, FDA, macro event). Worth flagging.
- Positive — calls richer than puts. Unusual for equities; signals bullish momentum, short-squeeze positioning, or takeover/M&A speculation.
- Near zero — symmetric surface. Market sees roughly equal up/down risk. Rare for large-caps; more common in commodities and FX.
Wing-vs-ATM tells you how expensive the tails are. Risk Reversal tells you which side is favored. Combined:
- High wing percentile + deeply negative RR → strong put bid; stress or major event priced in. Owning protection costs a premium; selling put premium is dangerous.
- Low wing percentile + near-zero RR → complacency; insurance cheap and balanced. Good environment to add cheap downside hedges.
- Positive RR + elevated wings → call-side fear-of-missing-out; common in squeeze setups. Upside calls expensive, downside puts not bid.
Percentile is the rank of today's reading within ~3 years of this symbol's own history. High percentile = wings are rich relative to history; not a directional signal. Skew is read off the chain in real time, not from CBOE SKEW.
Enter a ticker to render the implied volatility surface.
Enter a ticker to render the implied volatility smile.
Risk Metrics
Analysis Details
Data Points: 251
Period: 252 trading days
Above average volatility - stock moves with market amplification
APVO Institutional Ownership (13F)
Latest filings — 2026-09-30Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.
- Shares — long equity positions in this name, aggregated across share classes.
- Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
- % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
- Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.
Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.
| # | Filer | Notional Value | % of Total | Period |
|---|
| # | Filer | Notional Value | % of Total | Period |
|---|
APVO Insider Trading (Form 4)
Latest: 2026-08-10| Filed | Reporter | Role | Action | Shares | Avg Price | Net $ | Link |
|---|---|---|---|---|---|---|---|
| 2026-08-10 | Dirk Huebner | SVP, CMO | Mixed | +482 | $4.07 | -$635 | EDGAR |
| 2026-08-10 | Marvin L White | Executive Chair | Mixed | +1,261 | $4.07 | -$1.7K | EDGAR |
| 2026-08-10 | Barbara Lopez Kunz | Director | Exer (M) | +400 | — | EDGAR | |
| 2026-08-10 | John Niederhuber | Director | Exer (M) | +400 | — | EDGAR | |
| 2026-08-10 | Zsolt Harsanyi | Director | Exer (M) | +400 | — | EDGAR | |
| 2026-08-10 | Jeffrey G. Lamothe | President and CEO | Exer (M) | +961 | — | EDGAR | |
| 2026-08-10 | Grady Grant III | Director | Exer (M) | +400 | — | EDGAR | |
| 2026-08-10 | Daphne Taylor | SVP, CFO | Exer (M) | +638 | — | EDGAR | |
| 2026-08-10 | Daniel Abdun-Nabi | Director | Exer (M) | +400 | — | EDGAR | |
| 2026-08-10 | SoYoung Kwon | SVP, GC, BD & Corp Affairs | Exer (M) | +638 | — | EDGAR | |
| 2025-11-12 | Grady Grant III | Director | Buy (P) | +13,513 | $1.49 | $20.1K | EDGAR |
| 2025-08-08 | John Niederhuber | Director | Grant (A) | +7,200 RSU | — | EDGAR | |
| 2025-08-08 | Marvin L White | President and CEO | Grant (A) | +30,000 RSU | — | EDGAR | |
| 2025-08-08 | Jeffrey G. Lamothe | EVP, COO | Grant (A) | +17,300 RSU | — | EDGAR | |
| 2025-08-08 | Zsolt Harsanyi | Director | Grant (A) | +7,200 RSU | — | EDGAR |
APVO Insider Holdings
10 insiders · @ $1.50| # | Insider | Role | Shares | Disclosed Exposure | Lifetime OM Net | Filings | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Marvin L White | Executive Chair | 1,667 | $2.5K | $685.9K | 30 | 2026-08-10 |
| 2 | Grady Grant III | Director | 1,150 | $1.7K | $28.1K | 18 | 2026-08-10 |
| 3 | Jeffrey G. Lamothe | President and CEO | 961 | $1.4K | $0 | 29 | 2026-08-10 |
| 4 | Daphne Taylor | SVP, CFO | 638 | $957 | $0 | 10 | 2026-08-10 |
| 5 | Dirk Huebner | SVP, CMO | 638 | $957 | $0 | 2 | 2026-08-10 |
| 6 | SoYoung Kwon | SVP, GC, BD & Corp Affairs | 638 | $957 | $0 | 16 | 2026-08-10 |
| 7 | Zsolt Harsanyi | Director | 400 | $600 | $39.0K | 17 | 2026-08-10 |
| 8 | Daniel Abdun-Nabi | Director | 400 | $600 | $15.0K | 18 | 2026-08-10 |
| 9 | John Niederhuber | Director | 400 | $600 | $650 | 16 | 2026-08-10 |
| 10 | Barbara Lopez Kunz | Director | 400 | $600 | $8.5K | 17 | 2026-08-10 |
APVO Board & Officers
As of SEC filings through Aug 10, 2026Directors 7
- Zsolt Harsanyi · since Jul 15, 2016
- Marvin L White · since Jul 29, 2016
- Barbara Lopez Kunz · since Aug 1, 2016
- Daniel Abdun-Nabi · since Aug 1, 2016
- Grady Grant III · since Aug 1, 2016
- John Niederhuber · since Aug 1, 2016
- Jeffrey G. Lamothe · listed since Aug 2026
Officers 6
- Marvin L White · President and CEO · since Jul 29, 2016
- Daphne Taylor · SVP, CFO · since Mar 3, 2023
- Jeffrey G. Lamothe · EVP, COO · listed since Mar 2023
- SoYoung Kwon · SVP, GC, BD & Corp Affairs · listed since Mar 2023
- Dirk Huebner · SVP, CMO · since Jul 1, 2025
- Mary Jo Janatpour · SVP, Cso · since May 20, 2026
10% owners 1
- Niowave, Inc. (entity) · since May 25, 2026
Changes in the last 10 years (30)
| Aug 10, 2026 | Jeffrey G. Lamothe first listed as a director in an SEC filing |
| May 25, 2026 | Niowave, Inc. became a 10% owner |
| May 20, 2026 | Mary Jo Janatpour became SVP, Cso |
| Oct 3, 2025 | Bofa Securities, Inc. reported in an SEC filing no longer being a 10% owner |
| Oct 3, 2025 | Bank of America Na reported in an SEC filing no longer being a 10% owner |
| Oct 3, 2025 | Bank of America Corp /de/ reported in an SEC filing no longer being a 10% owner |
| Sep 30, 2025 | Bofa Securities, Inc. became a 10% owner |
| Sep 30, 2025 | Bank of America Na became a 10% owner |
| Sep 30, 2025 | Bank of America Corp /de/ became a 10% owner |
| Jul 1, 2025 | Dirk Huebner became SVP, CMO |
| Mar 7, 2023 | SoYoung Kwon listed as SVP, GC, BD & Corp Affairs (previously SVP, GC and Corporate Affairs) in SEC filings |
| Mar 7, 2023 | Jeffrey G. Lamothe listed as EVP, COO (previously CFO) in SEC filings |
| Mar 3, 2023 | Daphne Taylor became SVP, CFO |
| Mar 4, 2022 | SoYoung Kwon listed as SVP, GC and Corporate Affairs (previously Title - Secretary, SVP and General Counsel.) in SEC filings |
| Mar 4, 2022 | Jeffrey G. Lamothe listed as CFO (previously SVP and CFO) in SEC filings |
| Jan 21, 2022 | The company announced the departure of Fuad El-Hibri from the board in an SEC filing |
| Nov 26, 2021 | Tang Capital Partners LP reported in an SEC filing no longer being a 10% owner |
| Nov 26, 2021 | Tang Capital Management LLC reported in an SEC filing no longer being a 10% owner |
| Nov 26, 2021 | Kevin C Tang reported in an SEC filing no longer being a 10% owner |
| May 24, 2021 | SoYoung Kwon became Title - Secretary, SVP and General Counsel. |
| Nov 4, 2020 | Tang Capital Partners LP became a 10% owner |
| Nov 4, 2020 | Tang Capital Management LLC became a 10% owner |
| Nov 4, 2020 | Kevin C Tang became a 10% owner |
| Mar 19, 2020 | Jeffrey G. Lamothe listed as SVP and CFO (previously SVP, CFO and Treasurer) in SEC filings |
| Mar 19, 2020 | Jane A Gross listed as SVP & Chief Scientific Officer (previously Title - SVP, Research and Non-Clinical Development) in SEC filings |
| Aug 19, 2019 | Randy Joe Maddux listed as SVP Operations, CMO (previously Senior VP, Operations) in SEC filings |
| Aug 13, 2019 | Fuad El-Hibri no longer listed as a 10% owner in SEC filings |
| Aug 1, 2018 | Shawnte Mitchell became SVP, GC and Corporate Affairs |
| Aug 1, 2018 | Michael Adelman became SVP, Commercial Operations |
| Jun 4, 2018 | Fuad El-Hibri first listed as a 10% owner in an SEC filing |
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Not reported recently (5)
- Jane A Gross · Last reported as SVP & Chief Scientific Officer in an SEC filing dated Feb 17, 2021
- Randy Joe Maddux · Last reported as SVP Operations, CMO in an SEC filing dated Jul 29, 2020
- Shawnte Mitchell · Last reported as SVP, GC and Corporate Affairs in an SEC filing dated Mar 19, 2020
- Michael Adelman · Last reported as SVP, Commercial Operations in an SEC filing dated Mar 19, 2020
- Scott C Stromatt · Last reported as Chief Medical Officer and SVP in an SEC filing dated Mar 4, 2019
| # | ETF | Provider | Weight | $ Exposure | ETF AUM | As Of |
|---|---|---|---|---|---|---|
| 1 | VXF Vanguard Extended Market ETF | Vanguard | 0.00% | $23,138 | — | 2026-09-30 |
Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.
- Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
- Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
- Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
- Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
- Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
- YoY growth — compare to the same quarter a year earlier to remove seasonality.
- Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
- Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.
TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.