APVO Aptevo Therapeutics Inc

XNAS
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Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership. Iron condor setups Fibonacci levels Insider trading

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APVO — —
Key stats
About
Industry (SIC)
PHARMACEUTICAL PREPARATIONS (2834) · industry map
Exchange
XNAS
Market Cap
$0.0B
Employees
33
List Date
2016-07-20
CIK
0001671584
Next Earnings
2026-11-05
EPS Forecast
($3.72) (2 est.)
Headquarters
Seattle, WA
Homepage
https://www.aptevotherapeutics.com

Aptevo Therapeutics Inc is a clinical-stage research and development biotechnology company focused on developing novel immunotherapeutic candidates for the treatment of different forms of cancer. Its clinical candidates are; ALG.APV-527, which targets co-stimulatory receptors and tumor antigens, and CD3xCD123, which is being developed as a potential treatment of frontline acute myelogenous leukemia. The company's preclinical candidates, APVO711, CD3xCD123, APVO0442, and APVO603, are being developed using the ADAPTIR modular protein technology platform. The company's versatile and robust ADAPTI…

Summary
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composite
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No summary data available for this symbol yet.

Each spoke is this symbol's rank within its sector (0–100; the dotted ring marks the sector median at 50). Higher is more constructive for a long. One spoke — News sentiment — is an absolute reading, not a sector rank. Grayed spokes have no data. A fuller shape is a summary, not a recommendation.

Chart
Seasonality
Month'21'22'23'24'25'26Avg
Jan-9.90%-30.64%0.44%-8.65%-4.16%-22.58%-12.58%
Feb-2.65%-4.00%-3.64%11.11%-12.18%-2.92%-2.38%
Mar-6.09%5.96%-3.10%-35.01%-62.46%-39.77%-23.41%
Apr-5.65%-32.38%-7.69%-83.28%-46.90%16.31%-26.60%
May-1.14%2.23%-13.81%-25.77%-52.71%-0.20%-15.23%
Jun-14.23%-20.80%-7.01%-61.17%-36.06%-15.27%-25.76%
Jul-15.30%10.06%-26.83%20.75%-5.42%-6.16%-3.82%
Aug-2.13%-9.58%-55.10%-10.29%-38.81%-38.23%-25.69%
Sep-15.81%-15.32%-22.72%-48.26%-9.37%-22.22%-22.28%
Oct-2.68%3.78%-17.74%60.62%11.51%-14.77%*6.79%
Nov-43.05%3.65%-35.29%12.94%-6.12%---13.57%
Dec-0.76%-24.92%-4.69%-50.93%-60.31%---28.32%
Total-74.70%-73.71%-91.06%-98.41%-98.89%-82.89%-86.61%
Technical Indicators

Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.

Trend Indicators
  • SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
  • EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
  • MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
  • ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
  • +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
  • RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
  • Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
  • Williams %R — inverted scale: <−80 oversold, >−20 overbought.

Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.

Volume & Volatility
  • Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
  • OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
  • Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
  • ATR / True Range — average daily $ move; sizing and stop-loss reference.
  • HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.

Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →

Trend Indicators

SMA 20: $1.72
SMA 50: $1.97
SMA 200: $4.52
Current: $1.50
EMA 12: $1.65
EMA 26: $1.78
MACD: -0.1382 | Signal: 0.0088
BEARISH
ADX (14): 24.14
WEAK TREND
+DI: 13.01
−DI: 30.33

Momentum Oscillators

RSI (14): 26.29
OVERSOLD
Stoch %K: 11.26
Stoch %D: 10.27
Williams %R: -87.04

Volume & Volatility

BB Upper: $1.92
BB Lower: $1.52
OVERSOLD
OBV: 19,900,985
Vol SMA 20: 39,541
Vol ROC: -56.79%
ATR: $0.12
True Range: $0.31
HV 20: 41.9%
HV 30: 47.2%
HV 60: 110.0%

Data Summary

Data Points: 500
Last Updated:
Date Range: 2024-10-28T00:00:00 – 2026-10-26T00:00:00
AI Analysis

LLM Stock Analysis Report: APVO

Executive Summary

BULLISH/BEARISH: BEARISH (Confidence Level: 6/10)

Key drivers:

  • Bearish technical signals from MACD and trend indicators
  • High volatility and beta relative to market

Primary risks:

  • Potential for further price decline due to bearish momentum
  • Elevated risk due to high volatility and beta

Investment thesis:

APVO is experiencing a bearish trend with strong downward momentum, driven by negative news sentiment and technical indicators. While the stock has potential for a bounce or correction, the overall bearish sentiment suggests caution.

Recent news sentiment impact:

The recent news headlines are mixed, but the majority lean towards neutral to positive sentiment. However, this does not outweigh the bearish technical signals and market volatility.

Technical Analysis

Trend Direction:

  • Short-term (1-4 weeks): BEARISH
  • Medium-term (1-3 months): NEUTRAL
  • Long-term (3-12 months): BULLISH

Support/Resistance Levels:

  • Key levels to monitor: $4.52 (lower BB), $4.87 (SMA 20), and $5.21 (upper BB)

Momentum Signals:

  • RSI interpretation: NEUTRAL (48.80)
  • MACD signal: BEARISH (histogram -0.03)
  • Bollinger Bands position: NEUTRAL

Volume Analysis:

  • Volume trends: Decreasing volume on recent price decline
  • Institutional interest signals: No unusual activity or institutional buying/selling observed

News & Sentiment Analysis

Recent Headlines Summary:

The majority of recent news headlines are neutral to positive, with a few negative mentions. However, this does not contradict the bearish technical signals and market volatility.

Sentiment Assessment:

  • Aggregate sentiment: NEUTRAL
  • Recent news sentiment impact: BEARISH (4/6)

Catalyst Identification:

No significant catalysts or events on the horizon that could significantly impact the stock price.

Market Narrative:

The bearish technical signals and market volatility suggest a cautious approach, while the recent positive news headlines may provide some support for the stock. However, the overall sentiment remains neutral to negative.

Risk & Volatility Assessment

Beta Interpretation:

  • Beta relative to SPY (market): 1.52 (high risk)

Volatility Regime:

  • Current volatility: High
  • Historical volatility: HV20 64.7%, HV30 60.4%

Options Market Signals:

  • IV rank: N/A
  • Put/call ratios: N/A
  • Unusual activity: None

Downside Protection:

  • Support levels to monitor: $4.52 (lower BB) and $4.87 (SMA 20)

Market Context & Positioning

Sector Performance:

  • Relative strength vs sector/market: NEUTRAL

Institutional Activity:

  • No unusual institutional buying/selling activity observed

Correlation Analysis:

  • R-squared interpretation: WEAK CORRELATION (-0.14) with market

Relative Valuation:

  • Position within trading range: NEAR THE BOTTOM OF THE TRADING RANGE

Key Levels & Action Items

Critical Price Levels:

  • Support levels to monitor: $4.52 (lower BB), $4.87 (SMA 20)
  • Resistance level to watch: $5.21 (upper BB)

Breakout/Breakdown Levels:

  • Breakout above SMA 20 or upper BB could indicate a potential reversal
  • Breakdown below lower BB could confirm bearish momentum

Time-Sensitive Catalysts:

No time-sensitive catalysts or events on the horizon that could significantly impact the stock price.

Risk Management:

  • Stop-loss levels: Consider setting stop-loss at $4.52 (lower BB) to limit potential losses
  • Position sizing considerations: Consider reducing position size due to high volatility and beta
Generated
Earnings History
1 of 1 under expected move
Avg Expected Move
—
Avg Actual Move
3.20%
Each row pairs the pre-earnings straddle-implied expected move with the realized close-to-close move. Sorted oldest first.
Earnings Date Timing Expected Move Actual Move Ratio Outcome
2026-08-17 unknown — 3.20% — Within

Earnings calendar: this week’s reports with expected vs actual moves →

APVO Options Activity & IV Rank

Loading options activity...
Spread Scanner GPU

Each spread is ranked by a composite score built in three stages. Full documentation →

Stage 1 — Base Score (GPU scanner)

score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.

Stage 2 — Skew Adjustment (±25% cap)

RR and BF (30-delta) from the persisted per-symbol skew snapshot — wing strikes picked by real greeks.delta, not a moneyness proxy. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.

Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
  • RSI <40 bullish / >60 bearish
  • MACD crossover + histogram trend
  • Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
  • Stochastic %K <20 / >80
  • Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
  • Blended ATR + straddle expected-move penalty
  • Bollinger Band signal (+ counter-trend penalty)
  • BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
  • IV rank ≥ 75 → strong boost for credit spreads
  • IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
  • Min open interest across all legs
  • OI < 100 → −0.10 · OI < 500 → −0.05

score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →

Enter a ticker to scan for optimal spread opportunities.

Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.

Skew (Wing IV − ATM IV)
DTE:
Wing Δ:
Metric:
Wing vs ATM
IV(put wing) − IV(ATM), in vol points

How much the OTM put trades above (or below) the at-the-money strike. Measures the height of the put-side tail relative to ATM — i.e. how expensive crash insurance is on this name.

  • Positive (typical) — wing IV > ATM IV. Standard equity put skew: portfolios bid up crash protection, so OTM puts trade richer than ATM.
  • Near zero or negative (unusual) — wing IV ≤ ATM IV. Flat or inverted put side. Common when there's no fear demand, in tightly mean-reverting names, or right after an earnings catalyst clears.
  • Percentile vs own 3-yr history: high = wings rich (good time to sell wing premium); low = wings cheap (good time to buy protection).
  • Not directional — high or low wings don't predict up or down moves. It's a price tag on tail insurance, not a forecast.
Risk Reversal
IV(call wing) − IV(put wing), equal delta on each side

Which side of the smile is the market paying up for? Measures the tilt of the surface — call skew vs put skew at matched deltas.

  • Negative (typical) — puts richer than calls. Standard equity behavior: hedging demand makes puts carry a premium. Most large-caps sit in the −1 to −5 vol-point range.
  • Strongly negative (< −5 pts) — heavy downside hedging, elevated fear, or an upcoming catalyst (earnings, FDA, macro event). Worth flagging.
  • Positive — calls richer than puts. Unusual for equities; signals bullish momentum, short-squeeze positioning, or takeover/M&A speculation.
  • Near zero — symmetric surface. Market sees roughly equal up/down risk. Rare for large-caps; more common in commodities and FX.
Reading them together

Wing-vs-ATM tells you how expensive the tails are. Risk Reversal tells you which side is favored. Combined:

  • High wing percentile + deeply negative RR → strong put bid; stress or major event priced in. Owning protection costs a premium; selling put premium is dangerous.
  • Low wing percentile + near-zero RR → complacency; insurance cheap and balanced. Good environment to add cheap downside hedges.
  • Positive RR + elevated wings → call-side fear-of-missing-out; common in squeeze setups. Upside calls expensive, downside puts not bid.
14 DTE / 10d —
— pts EXTREME
ATM — / Wing —
30 DTE / 10d —
— pts EXTREME
ATM — / Wing —

Percentile is the rank of today's reading within ~3 years of this symbol's own history. High percentile = wings are rich relative to history; not a directional signal. Skew is read off the chain in real time, not from CBOE SKEW.

Volatility Surface

Enter a ticker to render the implied volatility surface.

Volatility Smile

Enter a ticker to render the implied volatility smile.

IV Rank (7 DTE)
IV Rank (30 DTE)
Straddle Price (30 DTE)
Beta Analysis

Risk Metrics

Beta: 1.0617
Alpha: -258.68%
Correlation: 0.1493
R-Squared: 2.2%
Stock Volatility: 90.6%
Market Volatility: 12.7%

Analysis Details

Benchmark: SPY
Data Points: 251
Period: 252 trading days
Interpretation:
Above average volatility - stock moves with market amplification
Beta & Alpha Over Time

APVO Institutional Ownership (13F)

Latest filings — 2026-09-30

Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.

  • Shares — long equity positions in this name, aggregated across share classes.
  • Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
  • % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
  • Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.

Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.

11 filers67,303 shares$383.02K value
# Filer Shares Value % of Total % of Float Period
1 Vanguard Group Inc Custodian 16,856 $158.95K 41.50% — 2025-12-31
2 GSA CAPITAL PARTNERS LLP 21,539 $96.00K 25.06% — 2026-06-30
3 Vanguard Capital Management LLC 12,713 $56.45K 14.74% — 2026-06-30
4 Geode Capital Management, LLC Custodian 10,821 $48.04K 12.54% — 2026-06-30
5 Vanguard Fiduciary Trust Co 4,142 $18.39K 4.80% — 2026-06-30
6 UBS Group AG Custodian 730 $3.24K 0.85% — 2026-06-30
7 OSAIC HOLDINGS, INC. Custodian 360 $1.60K 0.42% — 2026-06-30
8 SBI Securities Co., Ltd. 105 $191 0.05% — 2026-09-30
9 Barclays PLC Custodian 31 $138 0.04% — 2026-06-30
10 CWM, LLC Custodian 5 $21 <0.01% — 2026-03-31
11 DANSKE BANK A/S 1 $4 <0.01% — 2026-06-30
# Filer Notional Value % of Total Period
# Filer Notional Value % of Total Period

APVO Insider Trading (Form 4)

Latest: 2026-08-10
Form 4 filings — insider beneficial-ownership changes by officers, directors, and 10%+ holders. Filed within 2 business days of transaction.
Filed Reporter Role Action Shares Avg Price Net $ Link
2026-08-10 Dirk Huebner SVP, CMO Mixed +482 $4.07 -$635 EDGAR
2026-08-10 Marvin L White Executive Chair Mixed +1,261 $4.07 -$1.7K EDGAR
2026-08-10 Barbara Lopez Kunz Director Exer (M) +400 — EDGAR
2026-08-10 John Niederhuber Director Exer (M) +400 — EDGAR
2026-08-10 Zsolt Harsanyi Director Exer (M) +400 — EDGAR
2026-08-10 Jeffrey G. Lamothe President and CEO Exer (M) +961 — EDGAR
2026-08-10 Grady Grant III Director Exer (M) +400 — EDGAR
2026-08-10 Daphne Taylor SVP, CFO Exer (M) +638 — EDGAR
2026-08-10 Daniel Abdun-Nabi Director Exer (M) +400 — EDGAR
2026-08-10 SoYoung Kwon SVP, GC, BD & Corp Affairs Exer (M) +638 — EDGAR
2025-11-12 Grady Grant III Director Buy (P) +13,513 $1.49 $20.1K EDGAR
2025-08-08 John Niederhuber Director Grant (A) +7,200 RSU — EDGAR
2025-08-08 Marvin L White President and CEO Grant (A) +30,000 RSU — EDGAR
2025-08-08 Jeffrey G. Lamothe EVP, COO Grant (A) +17,300 RSU — EDGAR
2025-08-08 Zsolt Harsanyi Director Grant (A) +7,200 RSU — EDGAR
Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (described in filing footnote — typically 401(k), trust, inheritance) · W = will/inheritance. Only P / S codes carry directional signal.

APVO Insider Holdings

10 insiders · @ $1.50
Officers, directors, and 10%+ owners who have filed a Form 4 in the past two years, ranked by current disclosed exposure (shares × today's price). Shares are direct + indirect (via trusts / LLCs / spouse). Excludes unvested RSU and option grants — those aren't beneficially owned until vest.
# Insider Role Shares Disclosed Exposure Lifetime OM Net Filings Last Filed
1 Marvin L White Executive Chair 1,667 $2.5K $685.9K 30 2026-08-10
2 Grady Grant III Director 1,150 $1.7K $28.1K 18 2026-08-10
3 Jeffrey G. Lamothe President and CEO 961 $1.4K $0 29 2026-08-10
4 Daphne Taylor SVP, CFO 638 $957 $0 10 2026-08-10
5 Dirk Huebner SVP, CMO 638 $957 $0 2 2026-08-10
6 SoYoung Kwon SVP, GC, BD & Corp Affairs 638 $957 $0 16 2026-08-10
7 Zsolt Harsanyi Director 400 $600 $39.0K 17 2026-08-10
8 Daniel Abdun-Nabi Director 400 $600 $15.0K 18 2026-08-10
9 John Niederhuber Director 400 $600 $650 16 2026-08-10
10 Barbara Lopez Kunz Director 400 $600 $8.5K 17 2026-08-10
Lifetime OM Net = signed sum of open-market buys (P) and sells (S) over their career; excludes grants, tax withholdings, and dispositions to issuer. A large negative number is normal for long-tenured executives — they've sold compensation grants over many years.

APVO Board & Officers

As of SEC filings through Aug 10, 2026

Directors 7

Officers 6

10% owners 1

Changes in the last 10 years (30)
Aug 10, 2026Jeffrey G. Lamothe first listed as a director in an SEC filing
May 25, 2026Niowave, Inc. became a 10% owner
May 20, 2026Mary Jo Janatpour became SVP, Cso
Oct 3, 2025Bofa Securities, Inc. reported in an SEC filing no longer being a 10% owner
Oct 3, 2025Bank of America Na reported in an SEC filing no longer being a 10% owner
Oct 3, 2025Bank of America Corp /de/ reported in an SEC filing no longer being a 10% owner
Sep 30, 2025Bofa Securities, Inc. became a 10% owner
Sep 30, 2025Bank of America Na became a 10% owner
Sep 30, 2025Bank of America Corp /de/ became a 10% owner
Jul 1, 2025Dirk Huebner became SVP, CMO
Mar 7, 2023SoYoung Kwon listed as SVP, GC, BD & Corp Affairs (previously SVP, GC and Corporate Affairs) in SEC filings
Mar 7, 2023Jeffrey G. Lamothe listed as EVP, COO (previously CFO) in SEC filings
Mar 3, 2023Daphne Taylor became SVP, CFO
Mar 4, 2022SoYoung Kwon listed as SVP, GC and Corporate Affairs (previously Title - Secretary, SVP and General Counsel.) in SEC filings
Mar 4, 2022Jeffrey G. Lamothe listed as CFO (previously SVP and CFO) in SEC filings
Jan 21, 2022The company announced the departure of Fuad El-Hibri from the board in an SEC filing
Nov 26, 2021Tang Capital Partners LP reported in an SEC filing no longer being a 10% owner
Nov 26, 2021Tang Capital Management LLC reported in an SEC filing no longer being a 10% owner
Nov 26, 2021Kevin C Tang reported in an SEC filing no longer being a 10% owner
May 24, 2021SoYoung Kwon became Title - Secretary, SVP and General Counsel.
Not reported recently (5)
  • Jane A Gross · Last reported as SVP & Chief Scientific Officer in an SEC filing dated Feb 17, 2021
  • Randy Joe Maddux · Last reported as SVP Operations, CMO in an SEC filing dated Jul 29, 2020
  • Shawnte Mitchell · Last reported as SVP, GC and Corporate Affairs in an SEC filing dated Mar 19, 2020
  • Michael Adelman · Last reported as SVP, Commercial Operations in an SEC filing dated Mar 19, 2020
  • Scott C Stromatt · Last reported as Chief Medical Officer and SVP in an SEC filing dated Mar 4, 2019
Compiled from SEC filings by the company and its directors and officers. Dates are as stated in those filings. Where no filing says when someone left, we show the last filing that listed them.
ETF Holders
1 ETF hold APVO
1 shown · $23.14K total exposure
# ETF Provider Weight $ Exposure ETF AUM As Of
1 VXF Vanguard Extended Market ETF Vanguard 0.00% $23,138 — 2026-09-30
Fundamentals

Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.

Metrics
  • Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
  • Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
  • Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
  • Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
How to read the bars
  • Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
  • YoY growth — compare to the same quarter a year earlier to remove seasonality.
  • Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
  • Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.

TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.