Caribou Biosciences, Inc. Common Stock(CRBU)

Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership.

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.

Snapshot
$1.64
52-Week Range
$1.04 – $3.54
YTD
+3.14%
IV Rank (30D)
59.43
Straddle Price
$0.50
P/C Vol Ratio
0.21
Market Cap
$0.2B
Fair Value
+17.8% vs price
Confidence: 13% Alpha Score: 0.33

A blended fair-value estimate combining up to six valuation methods. Each method is weighted by how well it fits the company — DCF down-weights for unprofitable names; DDM only fires for steady dividend payers; comparables down-weight when peer multiples disagree.

  • DCF (quality-aware) — projects free cash flow with a horizon that scales to business quality. True compounders (quality 6/6) get 10 years explicit + 10 years fade before terminal; cyclical/struggling names (quality 0-1) get a 5-year terminal cliff. Quality is scored from ROE, gross margin, growth, FCF margin, debt load, and FCF consistency — the same factors that drive market premium for compounders.
  • Market-Implied Growth (in Model Inputs) — reverse-DCF that answers "what growth rate is the market pricing in?". Lets you sanity-check the deviation: if implied growth is plausible for the business, the model's bearish flag may be wrong; if implausible, the market may be over-extrapolating.
  • DDM (Gordon Growth Dividend Model) — values the stream of future dividends. Only used when trailing yield ≥ 0.5% and dividend payments are stable.
  • P/E, EV/EBITDA, P/B, P/S — applies the peer-group median multiple to this company's per-share metric. Peers come from the same set as the "Related symbols" card. Earnings/sales metrics are forward-tilted by the company's recent revenue growth (capped at 25%) so they're comparable to peers' growth-embedded multiples — mimics how analysts use NTM rather than TTM. Per-multiple weights are biased by company quality (e.g. P/B down-weighted for asset-light tech).
  • Market Anchor (SMA50) — the 50-day moving average, weighted by recent trading-range stability (tighter Bollinger bands → higher weight). Captures information fundamentals miss (forward consensus, sentiment, supply/demand) — but only when recent trading is steady enough that the market has converged on a view. During wild breakouts or breakdowns the anchor's weight collapses.
  • Options Expected (B-L 30d) — the risk-neutral expected stock price at 30-day options expiration, derived from the full implied-volatility surface via Breeden-Litzenberger (second derivative of call price wrt strike → implied PDF, then E[S_T]). Forward-looking, captures all options-implied information (smile, skew, term structure) in one number. Weighted by chain liquidity. SP500-only at present (pre-computed daily). Backtest evidence: adds modest alpha across most bucket × holding combos.
  • Blended value — weighted average. Confidence reflects how many methods fired and how tight peer dispersion is.
  • Deviation pill — green when blended FV ≥ 10% above current price (undervalued); red when ≥ 10% below; grey otherwise.
10-yr Treasury (rf)4.53%
Beta vs SPY1.00
Cost of Equity (CAPM)10.03% (VRP-adj)
WACC10.01%
Volatility Risk Premium+134.9pp (IV − HV30), ERP adj +50bps
Effective Tax Rate21.0%
Rev. Growth (YoY, DCF input)-10.0%
DCF Horizon10 years explicit + fade
Free Cash Flow (TTM)$-0.1B
Return on Equity (TTM)-130.7%
Book / Price65.5% — banking bias active (P/B is primary)
Gross Margin (TTM)100.0%
FCF Margin (TTM)-907.3%
Debt / Equity0.00
Quality Score2/6 — normal (10y DCF)
SMA 50$2.05 (Market Anchor value)
SMA 20 / Bollinger Mid$2.07
Bollinger Width / SMA201878.7% (drives anchor stability)
Net Debt$-0.0B
Market Cap$0B
Peers used for multiples: BMRN, CRSP, VCYT (filtered from 8 ETF-co-members; sector bias active)
Blended Fair Value
$1.88
Current Price
$1.59
Deviation
+17.8%
Forward-Return Rank LONG gates ✓
?
Horizon Expected α z Pred Blended z Rank % Active?
21d -1.8% +0.34 +0.37 49.2%
42d -2.2% +0.54 +0.46 52.8%
63d +0.6% +0.99 +0.69 63.8%
Expected α = forward-return point estimate vs SPY (e.g., +7.5% means the predictor expects this stock to outperform SPY by 7.5% over that horizon). For SHORT direction the model uses a different ranking metric (conviction-weighted deviation, not the LGBM prediction); Expected α is shown for reference. flags rows where Expected α disagrees with the FV direction — two independent signals are in conflict; conviction is low even if rank looks extreme.
Forward-Return Rank. A proprietary ensemble of a machine-learning forward-return model and a conviction-weighted fundamental score, ranked cross-sectionally each day across the S&P 500 (and broader universes on the screener). Each stock is scored at three horizons (21/42/63 trading days). "Active" = top/bottom 5% AND all risk filters pass. Backtested mean alpha vs SPY on active picks: 21d LONG +13.4%, 63d +34.9% (S&P 500, walk-forward). Past performance is not indicative of future results.
Value vs momentum conflict ⚠. The "FV direction" (long/short) comes from the fundamentals-based engine — price vs intrinsic value. The "Expected α" comes from a separate machine-learning predictor trained on ~12 features (sector, options-implied move, beta, institutional flow, etc.). Sometimes the two disagree: a stock is overvalued by fundamentals but the predictor expects it to keep outperforming (sector or momentum tailwinds). When all 3 horizons disagree, treat the direction signal as low-conviction — neither model is strongly recommending a position.
MethodImplied PriceWeightDetail
DCF n/a 0%
DDM (Gordon) n/a 0%
Peer P/E n/a 0%
Peer EV/EBITDA n/a 0%
Peer P/B $2.91 50% median 2.7× · 3 peers
Peer P/S $0.85 50% median 7.1× · 3 peers
Market Anchor (SMA50) $2.05 0% stability 0% (BB-width)
Options Expected (B-L 30d) n/a 0%
As of 2026-06-12 · updated 2026-06-12 20:59:55.687000
Info
Industry (SIC)
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES) (2836)
Exchange
XNAS
Market Cap
$0.2B

Caribou Biosciences Inc is a clinical-stage Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) genome-editing biopharmaceutical company dedicated to developing transformative therapies for patients with devastating diseases. The company is focused on advancing two clinical-stage allogeneic CAR-T cell therapy product candidates for the treatment of patients with hematologic malignancies: Vispacabtagene regedleucel and CB-011. It operates in one reportable segment, which is the business of developing allogeneic CAR-T cell therapies. Geographically, it operates in the United State…

Price History
Seasonality
MonthAvg ReturnYears of Data
Jan -7.91% 5
Feb +4.34% 5
Mar -9.28% 5
Apr -14.88% 5
May +6.86% 5
Jun -13.57% 5
Jul +43.67% 5
Aug +8.45% 5
Sep -2.50% 5
Oct -4.98% 5
Nov -2.51% 5
Dec -17.55% 5
Technical Indicators

Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.

Trend Indicators
  • SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
  • EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
  • MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
  • ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
  • +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
  • RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
  • Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
  • Williams %R — inverted scale: <−80 oversold, >−20 overbought.

Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.

Volume & Volatility
  • Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
  • OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
  • Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
  • ATR / True Range — average daily $ move; sizing and stop-loss reference.
  • HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.

Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →

Trend Indicators
SMA 20: $2.04
SMA 50: $2.04
SMA 200: $1.95
Current: $1.59
EMA 12: $1.90
EMA 26: $1.99
MACD: -0.0881 | Signal: -0.0685
BEARISH
ADX (14): 21.35
WEAK TREND
+DI: 15.66
−DI: 29.26
Momentum Oscillators
RSI (14): 30.82
NEUTRAL
Stoch %K: 3.00
Stoch %D: 4.29
Williams %R: -99.44
Volume & Volatility
BB Upper: $2.49
BB Lower: $1.59
NEUTRAL
OBV: 65,631,991
Vol SMA 20: 1,869,394
Vol ROC: 65.03%
ATR: $0.16
True Range: $0.18
HV 20: 80.9%
HV 30: 72.1%
HV 60: 70.3%

Data Summary
Data Points: 500
Last Updated: 2026-06-13T13:41:23.146000
Date Range: 2024-06-14T00:00:00 – 2026-06-12T00:00:00
AI Analysis

Choose Frenzy-Fast™ for quick analysis or Frenzy-Pro™ for comprehensive analysis.

Analysis includes technical indicators, news sentiment, risk assessment, and specific price levels to watch.

Earnings History
8 of 8 under expected move
Each row pairs the pre-earnings straddle-implied expected move with the realized close-to-close move. Sorted oldest first.
Earnings Date Timing Expected Move Actual Move Ratio Outcome
2024-08-06 After-Close 40.00% 0.00% 0.00x Within
2024-11-06 Pre-Market 23.53% 3.14% 0.13x Within
2025-03-10 Pre-Market 247.84% 1.77% 0.01x Within
2025-05-08 Pre-Market 664.98% 5.57% 0.01x Within
2025-08-12 After-Close 48.85% 12.07% 0.25x Within
2025-11-12 After-Close 30.27% 10.99% 0.36x Within
2026-03-05 After-Close 54.57% 5.47% 0.10x Within
2026-05-07 After-Close 26.60% 3.19% 0.12x Within
Options Activity
IV Rank (30D)
59.43
IV Rank (7D)
100
Avg IV
222.1%
Straddle (30D)
$0.50
Straddle (7D)
$0.42
P/C Volume
0.21
Spread Scanner GPU

Each spread is ranked by a composite score built in three stages. Full documentation →

Stage 1 — Base Score (GPU scanner)

score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.

Stage 2 — Skew Adjustment (±25% cap)

RR25 and BF25 from the live options chain. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.

Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
  • RSI <40 bullish / >60 bearish
  • MACD crossover + histogram trend
  • Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
  • Stochastic %K <20 / >80
  • Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
  • Blended ATR + straddle expected-move penalty
  • Bollinger Band signal (+ counter-trend penalty)
  • BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
  • IV rank ≥ 75 → strong boost for credit spreads
  • IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
  • Min open interest across all legs
  • OI < 100 → −0.10 · OI < 500 → −0.05

score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →

Enter a ticker to scan for optimal spread opportunities.

Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.

Volatility Surface

Enter a ticker to render the implied volatility surface.

IV Rank (7 DTE)
IV Rank (30 DTE)
Straddle Price (30 DTE)
Beta Analysis
Beta (1Y vs SPY)
2.51
Correlation (SPY)
37.5%
0.14
Ann. Volatility
82.5%
SPY Volatility
12.3%

High volatility - stock moves more than market

Beta & Alpha Over Time
Institutional Ownership (13F)
Latest filings — 2026-03-31
Diluted shares outstanding: 93,893,199 (as of 2026-03-31)

Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.

  • Shares — long equity positions in this name, aggregated across share classes.
  • Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
  • % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
  • Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.

Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.

139 filers38,016,613 shares$66.37M value40.49% of float
# Filer Shares Value % of Total % of Float Period
1 PFIZER INC 4,690,431 $8.35M 12.58% 5.00% 2026-03-31
2 VANGUARD GROUP INC Custodian 4,304,198 $6.84M 10.31% 4.58% 2025-12-31
3 RENAISSANCE TECHNOLOGIES LLC 2,590,497 $4.92M 7.42% 2.76% 2026-03-31
4 Kynam Capital Management, LP 2,503,302 $4.76M 7.17% 2.67% 2026-03-31
5 BlackRock, Inc. Custodian 2,143,085 $4.07M 6.13% 2.28% 2026-03-31
6 TWO SIGMA INVESTMENTS, LP 1,759,934 $3.34M 5.04% 1.87% 2026-03-31
7 BANK OF AMERICA CORP /DE/ Custodian 1,297,167 $2.46M 3.71% 1.38% 2026-03-31
8 Aberdeen Group plc 1,212,541 $2.30M 3.47% 1.29% 2026-03-31
9 MARSHALL WACE, LLP Custodian 1,205,668 $2.29M 3.45% 1.28% 2026-03-31
10 MILLENNIUM MANAGEMENT LLC Custodian 1,074,421 $2.04M 3.08% 1.14% 2026-03-31
11 GEODE CAPITAL MANAGEMENT, LLC Custodian 1,017,959 $1.93M 2.92% 1.08% 2026-03-31
12 PFM Health Sciences, LP 957,787 $1.82M 2.74% 1.02% 2026-03-31
13 MACKENZIE FINANCIAL CORP 942,786 $1.79M 2.70% 1.00% 2026-03-31
14 SUSQUEHANNA INTERNATIONAL GROUP, LLP Custodian 836,903 $1.59M 2.40% 0.89% 2026-03-31
15 FMR LLC Custodian 723,959 $1.38M 2.07% 0.77% 2026-03-31
16 DIMENSIONAL FUND ADVISORS LP Custodian 673,200 $1.28M 1.93% 0.72% 2026-03-31
17 MAVERICK CAPITAL LTD 652,542 $1.24M 1.87% 0.69% 2026-03-31
18 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 559,642 $1.06M 1.60% 0.60% 2026-03-31
19 72 Investment Holdings, LLC 474,067 $900.73K 1.36% 0.50% 2026-03-31
20 STATE STREET CORP 423,263 $804.20K 1.21% 0.45% 2026-03-31
21 GOLDMAN SACHS GROUP INC Custodian 376,589 $715.52K 1.08% 0.40% 2026-03-31
22 Green Alpha Advisors, LLC 373,650 $709.93K 1.07% 0.40% 2026-03-31
23 JACOBS LEVY EQUITY MANAGEMENT, INC 358,941 $681.99K 1.03% 0.38% 2026-03-31
24 XTX Topco Ltd 323,469 $614.59K 0.93% 0.34% 2026-03-31
25 WELLS FARGO & COMPANY/MN Custodian 303,655 $576.95K 0.87% 0.32% 2026-03-31
5 filers$751.07K notional
# Filer Notional Value % of Total Period
1 SUSQUEHANNA INTERNATIONAL GROUP, LLP Custodian $307.99K 41.01% 2026-03-31
2 JANE STREET GROUP, LLC Custodian $164.35K 21.88% 2026-03-31
3 CITADEL ADVISORS LLC Custodian $126.35K 16.82% 2026-03-31
4 GROUP ONE TRADING LLC Custodian $92.72K 12.35% 2026-03-31
5 SIMPLEX TRADING, LLC Custodian $59.66K 7.94% 2026-03-31
4 filers$244.15K notional
# Filer Notional Value % of Total Period
1 CITADEL ADVISORS LLC Custodian $137.56K 56.34% 2026-03-31
2 SUSQUEHANNA INTERNATIONAL GROUP, LLP Custodian $91.58K 37.51% 2026-03-31
3 SIMPLEX TRADING, LLC Custodian $7.79K 3.19% 2026-03-31
4 GROUP ONE TRADING LLC Custodian $7.22K 2.96% 2026-03-31
Insider Activity
Latest: 2026-02-27
Form 4 filings — insider beneficial-ownership changes by officers, directors, and 10%+ holders. Filed within 2 business days of transaction.
Filed Reporter Role Action Shares Avg Price Net $ Link
2026-02-27 Timothy P Kelly Chief Technology Officer Sell (S) −6,228 $1.93 -$12.0K EDGAR
2026-02-24 Ruhi Ahmad Khan Chief Business Officer Mixed +38,062 $1.96 -$13.6K EDGAR
2026-02-24 Tina M. Albertson Chief Medical Officer Mixed +53,934 $1.96 -$2.1K EDGAR
2026-02-24 BARBARA G MCCLUNG Chief Legal Officer Mixed +38,062 $1.96 -$13.6K EDGAR
2026-02-24 Timothy P Kelly Chief Technology Officer Mixed +41,853 $1.96 -$6.2K EDGAR
2026-02-20 Dara Richardson-Heron Director Grant (A) +45,000 opt EDGAR
2026-02-20 Natalie Sacks Director Grant (A) +45,000 opt EDGAR
2026-02-20 DAVID LEE JOHNSON Director Grant (A) +45,000 opt EDGAR
2026-02-20 Nancy Whiting Director Grant (A) +45,000 opt EDGAR
2026-02-20 Ran Zheng Director Grant (A) +45,000 opt EDGAR
2026-02-20 ANDREW GUGGENHIME Director Grant (A) +45,000 opt EDGAR
2026-02-20 Scott Braunstein Director Grant (A) +45,000 opt EDGAR
2026-02-20 Rachel E. Haurwitz President and CEO Award (A) +151,700 EDGAR
2026-02-20 Sriram Ryali Chief Financial Officer Award (A) +55,000 EDGAR
2025-03-17 Rachel E. Haurwitz President and CEO Buy (P) +20,000 $1.02 $20.4K EDGAR
Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (described in filing footnote — typically 401(k), trust, inheritance) · W = will/inheritance. Only P / S codes carry directional signal.
Insider Holdings
11 insiders · @ $1.59
Officers, directors, and 10%+ owners ranked by current disclosed exposure (shares × today's price). Shares are direct + indirect (via trusts / LLCs / spouse). Excludes unvested RSU and option grants — those aren't beneficially owned until vest.
# Insider Role Shares Disclosed Exposure Lifetime OM Net Filings Last Filed
1 Rachel E. Haurwitz President and CEO 3,816,545 $6.09M $20.4K 11 2026-02-20
2 BARBARA G MCCLUNG Chief Legal Officer 481,564 $768.1K $22.9K 8 2026-02-24
3 Steven Kanner Chief Scientific Officer 431,556 $688.3K -$269.3K 10 2025-02-21
4 Ryan Fischesser VP of Finance and Controller 118,854 $189.6K -$70.7K 8 2024-11-22
5 Ruhi Ahmad Khan Chief Business Officer 111,936 $178.5K -$18.4K 6 2026-02-24
6 Timothy P Kelly Chief Technology Officer 73,125 $116.6K -$18.2K 4 2026-02-27
7 Sriram Ryali Chief Financial Officer 72,360 $115.4K $24.7K 3 2026-02-20
8 Tina M. Albertson Chief Medical Officer 69,589 $111.0K -$2.1K 3 2026-02-24
9 Syed Ali-aamir Rizvi Chief Medical Officer 59,373 $94.7K -$35.5K 3 2023-02-23
10 Jason O'Byrne Chief Financial Officer 59,224 $94.5K $0 4 2024-02-22
11 FMR LLC 17,572 $28.0K $0 1 2021-07-29
Lifetime OM Net = signed sum of open-market buys (P) and sells (S) over their career; excludes grants, tax withholdings, and dispositions to issuer. A large negative number is normal for long-tenured executives — they've sold compensation grants over many years.
ETF Holders
# ETF Provider Weight $ Exposure ETF AUM As Of
Fundamentals

Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.

Metrics
  • Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
  • Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
  • Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
  • Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
How to read the bars
  • Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
  • YoY growth — compare to the same quarter a year earlier to remove seasonality.
  • Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
  • Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.

TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.

P/B Ratio1.6
P/S Ratio14.7
EV/EBITDA-1.3
TTM Revenue$0.0B
TTM Net Income$-0.1B
TTM EPS$-1.42
ROE-130.7%