CRSP CRISPR Therapeutics AG
XNAS
51.47
Delayed
Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership. Iron condor setups Expected move IV rank history Fibonacci levels Insider trading
Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.
- 52-Week Range
- $44.12 – $67.73
- YTD
- -4.28%
- IV Rank (30D)
- 45.55
- Straddle Price
- $6.75
- P/C Vol Ratio
- 0.67
- Market Cap
- $4.7B
- Open
- $49.14
- Day Range
- $48.75 – $51.55
- Volume
- 1,166,902
- Prev Close
- $49.01
A blended fair-value estimate combining up to six valuation methods. Each method is weighted by how well it fits the company — DCF down-weights for unprofitable names; DDM only fires for steady dividend payers; comparables down-weight when peer multiples disagree.
- DCF (quality-aware) — projects free cash flow with a horizon that scales to business quality. True compounders (quality 6/6) get 10 years explicit + 10 years fade before terminal; cyclical/struggling names (quality 0-1) get a 5-year terminal cliff. Quality is scored from ROE, gross margin, growth, FCF margin, debt load, and FCF consistency — the same factors that drive market premium for compounders.
- Market-Implied Growth (in Model Inputs) — reverse-DCF that answers "what growth rate is the market pricing in?". Lets you sanity-check the deviation: if implied growth is plausible for the business, the model's bearish flag may be wrong; if implausible, the market may be over-extrapolating.
- DDM (Gordon Growth Dividend Model) — values the stream of future dividends. Only used when trailing yield ≥ 2% and dividend payments are stable — below that the dividend is a token payout and Gordon (which values only the dividend stream) systematically underprices growth names, so those route to DCF + comparables + market anchor instead.
- P/E, EV/EBITDA, P/B, P/S — applies the peer-group median multiple to this company's per-share metric. Peers come from the same set as the "Related symbols" card. Earnings/sales metrics are forward-tilted by the company's recent revenue growth (capped at 25%) so they're comparable to peers' growth-embedded multiples — mimics how analysts use NTM rather than TTM. Per-multiple weights are biased by company quality (e.g. P/B down-weighted for asset-light tech).
- Market Anchor (SMA50) — the 50-day moving average, weighted by recent trading-range stability (tighter Bollinger bands → higher weight). Captures information fundamentals miss (forward consensus, sentiment, supply/demand) — but only when recent trading is steady enough that the market has converged on a view. During wild breakouts or breakdowns the anchor's weight collapses.
- Options Expected (B-L 30d) — the risk-neutral expected stock price at 30-day options expiration, derived from the full implied-volatility surface via Breeden-Litzenberger (second derivative of call price wrt strike → implied PDF, then E[S_T]). Forward-looking, captures all options-implied information (smile, skew, term structure) in one number. Weighted by chain liquidity. SP500-only at present (pre-computed daily). Backtest evidence: adds modest alpha across most bucket × holding combos.
- Blended value — weighted average. Confidence reflects how many methods fired and how tight peer dispersion is.
- Deviation pill — green when blended FV ≥ 10% above current price (undervalued); red when ≥ 10% below; grey otherwise.
| 10-yr Treasury (rf) | 4.96% |
| Beta vs SPY | 1.26 |
| Cost of Equity (CAPM) | 11.78% (VRP-adj) |
| WACC | 11.15% |
| Volatility Risk Premium | +11.0pp (IV − HV30), ERP adj +40bps |
| Effective Tax Rate | 21.0% |
| Rev. Growth (YoY, DCF input) | +30.0% |
| DCF Horizon | 10 years explicit + fade |
| Forward Tilt (NTM/TTM) | ×1.10 (applied to P/E, EV/EBITDA, P/S) |
| Free Cash Flow (TTM) | $-0.4B |
| Return on Equity (TTM) | -25.8% |
| Book / Price | 40.6% — banking bias active (P/B is primary) |
| Gross Margin (TTM) | 100.0% |
| FCF Margin (TTM) | -9050.1% |
| Debt / Equity | 0.32 |
| Quality Score | 3/6 — normal (10y DCF) |
| SMA 50 | $54.47 (Market Anchor value) |
| SMA 20 / Bollinger Mid | $52.06 |
| Bollinger Width / SMA20 | 38.0% (drives anchor stability) |
| Net Debt | $0.2B |
| Market Cap | $4B |
| Method | Implied Price | Weight | Detail |
|---|---|---|---|
| DCF | n/a | 0% | |
| DDM (Gordon) | n/a | 0% | |
| Peer P/E | n/a | 0% | median 34.5× · 7 peers |
| Peer EV/EBITDA | n/a | 0% | median 18.3× · 8 peers |
| Peer P/B | $204.09 | 22% | median 10.2× · 10 peers |
| Peer P/S | $0.33 | 22% | median 6.6× · 9 peers |
| Market Anchor (SMA50) | $54.47 | 0% | stability 0% (BB-width) |
| Options Expected (B-L 30d) | $48.32 | 56% | 31 strikes · skew +0.17 |

- Industry (SIC)
- BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES) (2836) · industry map
- Exchange
- XNAS
- Market Cap
- $4.7B
- Employees
- 393
- List Date
- 2016-10-19
- CIK
- 0001674416
- Next Earnings
- 2026-11-09 (After-Close)
- EPS Forecast
- ($1.06) (8 est.)
- Headquarters
- Zug
- Homepage
- https://www.crisprtx.com
Crispr Therapeutics is a gene editing company focused on the development of Crispr/Cas9-based therapeutics. Crispr/Cas9 stands for clustered regularly interspaced short palindromic repeats (Crispr)/Crispr-associated protein 9 (Cas9), which is a revolutionary technology for precisely altering specific sequences of genomic DNA. The company is focused on using this technology to treat genetically defined diseases. Crispr's first approved drug is Casgevy, which was developed in collaboration with Vertex Pharmaceuticals and targets sickle-cell disease and transfusion-dependent beta-thalassemia. The…
Each spoke is this symbol's rank within its sector (0–100; the dotted ring marks the sector median at 50). Higher is more constructive for a long. One spoke — News sentiment — is an absolute reading, not a sector rank. Grayed spokes have no data. A fuller shape is a summary, not a recommendation.
| Month | '21 | '22 | '23 | '24 | '25 | '26 | Avg |
|---|---|---|---|---|---|---|---|
| Jan | 4.87% | -19.55% | 24.44% | -4.71% | 0.39% | -7.09% | -0.27% |
| Feb | -24.14% | -6.35% | -5.75% | 30.23% | 9.80% | 17.21% | 3.50% |
| Mar | -6.45% | 9.28% | -5.22% | -18.61% | -19.53% | -21.72% | -10.38% |
| Apr | 9.93% | -24.99% | 8.08% | -22.28% | 16.69% | 7.23% | -0.89% |
| May | -3.77% | 11.68% | 30.48% | -0.13% | -3.82% | 8.81% | 7.21% |
| Jun | 39.80% | 5.01% | -12.99% | -5.49% | 31.64% | 0.65% | 9.77% |
| Jul | -22.74% | 17.57% | 1.92% | 6.19% | 15.98% | -13.44% | 0.91% |
| Aug | 2.13% | -12.05% | -11.35% | -13.00% | -7.59% | 14.95% | -4.49% |
| Sep | -11.42% | -0.38% | -10.17% | 3.21% | 23.07% | -2.64% | 0.28% |
| Oct | -17.94% | -17.05% | -8.21% | 1.78% | -3.28% | -7.16%* | -8.64% |
| Nov | -16.30% | 5.32% | 52.53% | 0.81% | -13.72% | -- | 5.73% |
| Dec | 0.66% | -25.19% | -8.81% | -28.63% | 0.52% | -- | -12.29% |
| Total | -46.81% | -51.24% | 41.34% | -48.27% | 45.00% | -9.96% | -11.66% |
Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.
- SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
- EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
- MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
- ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
- +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
- RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
- Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
- Williams %R — inverted scale: <−80 oversold, >−20 overbought.
Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.
- Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
- OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
- Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
- ATR / True Range — average daily $ move; sizing and stop-loss reference.
- HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.
Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →
Trend Indicators
Momentum Oscillators
Volume & Volatility
Data Summary
Here is the structured report for the given stock data:
Executive Summary
BULLISH (Confidence level: 6/10)
Key drivers: Bullish momentum signals from technical indicators, positive news sentiment, and high institutional interest.
Primary risks: High volatility, potential overbought conditions, and market corrections.
Investment thesis: CRISPR Therapeutics has strong fundamental support and a favorable catalyst-rich environment, which may drive the stock price higher. Recent positive news headlines have boosted investor confidence.
Recent news sentiment impact: Positive news sentiment has been driving the stock price higher, with a mix of neutral and positive headlines over the past week.
Technical Analysis
Trend Direction: Short-term (1-4 weeks): Bullish; Medium-term (1-3 months): Neutral/Bullish; Long-term (3-12 months): Bullish
Support/Resistance Levels: Key price levels from moving averages and technical patterns:
- SMA 20: $56.55 (support)
- SMA 50: $53.76 (resistance)
- Upper Bollinger Band: $61.33 (resistance)
Momentum Signals:
- RSI interpretation: Neutral (50.70) - no strong momentum signal
- MACD signal: Bullish (1.19 / Signal: -0.35 / Histogram: 1.54)
- Bollinger Bands position: Squeeze
Volume Analysis: Volume trends and institutional interest signals:
- Volume SMA 20: 1424632.38
- On-Balance Volume (OBV): 23838698.74
- Volume Rate of Change: -63.54% ( bearish sentiment)
News & Sentiment Analysis
Recent Headlines Summary: Key themes from last 10 news articles:
- 3 positive headlines (Zacks Investment Research, The Motley Fool) highlighting company's prospects and catalysts.
- 1 neutral headline (Zacks Investment Research) discussing earnings report.
- No negative headlines.
Sentiment Assessment: Aggregate news sentiment: POSITIVE
Catalyst Identification: Upcoming events:
- Earnings reports
- Product launches
- Regulatory changes
Market Narrative: How news aligns with or contradicts technical signals:
- Positive news headlines have reinforced the bullish momentum, while neutral headlines have not significantly impacted the market narrative.
Risk & Volatility Assessment
Beta Interpretation: Risk relative to market (beta >1.2 = high risk): 1.81 - High volatility
Volatility Regime: Current vs historical volatility levels: High volatility, with a recent increase in implied volatility.
Options Market Signals: IV rank, put/call ratios, unusual activity:
- IV Rank: 26.5% (Medium) - shows if volatility is historically high/low
- Current IV: 65.4%
- Expected Move: $7.22 (28 DTE), 7-DTE: $3.20
Downside Protection: Support levels and risk management considerations:
- SMA 50: $53.76 (support)
- Lower Bollinger Band: $51.78 (support)
Market Context & Positioning
Sector Performance: Relative strength vs sector/market:
- CRISPR Therapeutics is outperforming the biotech sector.
Institutional Activity: Volume patterns suggesting institutional interest:
- High volume on recent buy signals
Correlation Analysis: How stock moves relative to market (R-squared interpretation):
- Correlation: 0.39 - a moderate positive correlation between CRISPR Therapeutics and the broader market.
Relative Valuation: Position within trading range:
- The stock is currently trading near its upper Bollinger Band, suggesting a potentially overbought condition.
Key Levels & Action Items
Critical Price Levels: Support/resistance to monitor:
- SMA 20: $56.55 (support)
- SMA 50: $53.76 (resistance)
- Upper Bollinger Band: $61.33 (resistance)
Breakout/Breakdown Levels: Technical levels that could trigger significant moves:
- Lower Bollinger Band: $51.78 (breakdown risk)
- SMA 200: $53.24 (support)
Time-Sensitive Catalysts: Earnings dates, FDA approvals, product launches:
- Upcoming earnings reports and potential catalysts may drive the stock price higher.
Risk Management: Stop-loss levels and position sizing considerations:
- Consider setting a stop-loss at the SMA 50 level ($53.76) to limit potential losses in case of a market correction.
- Monitor volume patterns for signs of institutional interest or selling pressure.
| Earnings Date | Timing | Expected Move | Actual Move | Ratio | Outcome |
|---|---|---|---|---|---|
| 2021-02-16 | After-Close | 4.89% | 3.41% | 0.70x | Within |
| 2021-04-27 | After-Close | 4.89% | 1.88% | 0.38x | Within |
| 2021-07-29 | After-Close | 5.49% | 1.70% | 0.31x | Within |
| 2021-11-03 | After-Close | 5.26% | 4.00% | 0.76x | Within |
| 2022-02-15 | After-Close | 6.81% | 1.64% | 0.24x | Within |
| 2022-05-09 | After-Close | 13.56% | 9.44% | 0.70x | Within |
| 2022-08-08 | After-Close | 5.15% | 7.69% | 1.49x | Exceeded |
| 2022-11-01 | After-Close | 6.92% | 5.11% | 0.74x | Within |
| 2023-02-21 | After-Close | 6.30% | 8.04% | 1.28x | Exceeded |
| 2023-05-08 | After-Close | 6.36% | 13.33% | 2.10x | Exceeded |
| 2023-08-07 | After-Close | 6.43% | 9.74% | 1.51x | Exceeded |
| 2023-11-06 | After-Close | 8.07% | 13.57% | 1.68x | Exceeded |
| 2024-02-21 | After-Close | 5.24% | 4.59% | 0.88x | Within |
| 2024-05-08 | After-Close | 6.87% | 0.49% | 0.07x | Within |
| 2024-08-05 | After-Close | 9.72% | 0.66% | 0.07x | Within |
| 2024-11-05 | After-Close | 6.65% | 0.71% | 0.11x | Within |
| 2025-02-11 | After-Close | 4.42% | 9.29% | 2.10x | Exceeded |
| 2025-05-06 | After-Close | 7.69% | 3.29% | 0.43x | Within |
| 2025-08-04 | After-Close | 7.17% | 6.71% | 0.94x | Within |
| 2025-11-10 | After-Close | 6.46% | 1.15% | 0.18x | Within |
| 2026-02-12 | After-Close | 4.75% | 8.46% | 1.78x | Exceeded |
| 2026-05-05 | After-Close | 4.58% | 5.15% | 1.12x | Exceeded |
| 2026-08-03 | After-Close | 9.28% | 7.06% | 0.76x | Within |
Earnings calendar: this week’s reports with expected vs actual moves →
CRSP Options Activity & IV Rank
CRSP IV rank history, 52-week IV rank and IV percentile →
Volatility Metrics
Options Flow
ATM Options Pricing
Chain Summary
Each spread is ranked by a composite score built in three stages. Full documentation →
score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.
RR and BF (30-delta) from the persisted per-symbol skew snapshot — wing strikes picked by real greeks.delta, not a moneyness proxy. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.
- RSI <40 bullish / >60 bearish
- MACD crossover + histogram trend
- Price vs SMA 50 & SMA 200
- Stochastic %K <20 / >80
- Williams %R <−80 / >−20
- Blended ATR + straddle expected-move penalty
- Bollinger Band signal (+ counter-trend penalty)
- BB width — vol contraction boost for ICs
- IV rank ≥ 75 → strong boost for credit spreads
- IV rank < 25 → penalty (selling cheap vol)
- Min open interest across all legs
- OI < 100 → −0.10 · OI < 500 → −0.05
score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →
Enter a ticker to scan for optimal spread opportunities.
Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.
Estimated net dealer gamma is at the 33rd percentile of this name's own daily history, within its typical range. This describes current positioning; it is not a forecast or a trading signal.
Net dealer gamma is an estimate of the aggregate gamma held by options market makers across this name's option chain, weighted by open interest. Dealer positions aren't public, so it uses a standard simplifying assumption: dealers are treated as long the calls and short the puts that are open. Actual dealer books can differ.
Gamma percentile ranks today's estimate against this name's own daily history, from 0% (the lowest reading on record) to 100% (the highest). Raw gamma scales with how much open interest a chain carries, so it isn't comparable across names; the percentile is. The badge marks the bottom 20% as low and the top 20% as high.
Tilts run from −1 to +1 and show how lopsided the estimated dealer exposure is. GEX tilt compares call gamma with put gamma. Vanna tilt describes how the hedge would shift if implied volatility changed, and charm tilt how it would shift with the passage of time.
This card describes estimated positioning and where it sits historically. It is not a forecast of price direction or volatility and not a trading signal. Market-wide view: Dealer positioning screener.
IV(put wing) − IV(ATM), in vol pointsHow much the OTM put trades above (or below) the at-the-money strike. Measures the height of the put-side tail relative to ATM — i.e. how expensive crash insurance is on this name.
- Positive (typical) — wing IV > ATM IV. Standard equity put skew: portfolios bid up crash protection, so OTM puts trade richer than ATM.
- Near zero or negative (unusual) — wing IV ≤ ATM IV. Flat or inverted put side. Common when there's no fear demand, in tightly mean-reverting names, or right after an earnings catalyst clears.
- Percentile vs own 3-yr history: high = wings rich (good time to sell wing premium); low = wings cheap (good time to buy protection).
- Not directional — high or low wings don't predict up or down moves. It's a price tag on tail insurance, not a forecast.
IV(call wing) − IV(put wing), equal delta on each sideWhich side of the smile is the market paying up for? Measures the tilt of the surface — call skew vs put skew at matched deltas.
- Negative (typical) — puts richer than calls. Standard equity behavior: hedging demand makes puts carry a premium. Most large-caps sit in the −1 to −5 vol-point range.
- Strongly negative (< −5 pts) — heavy downside hedging, elevated fear, or an upcoming catalyst (earnings, FDA, macro event). Worth flagging.
- Positive — calls richer than puts. Unusual for equities; signals bullish momentum, short-squeeze positioning, or takeover/M&A speculation.
- Near zero — symmetric surface. Market sees roughly equal up/down risk. Rare for large-caps; more common in commodities and FX.
Wing-vs-ATM tells you how expensive the tails are. Risk Reversal tells you which side is favored. Combined:
- High wing percentile + deeply negative RR → strong put bid; stress or major event priced in. Owning protection costs a premium; selling put premium is dangerous.
- Low wing percentile + near-zero RR → complacency; insurance cheap and balanced. Good environment to add cheap downside hedges.
- Positive RR + elevated wings → call-side fear-of-missing-out; common in squeeze setups. Upside calls expensive, downside puts not bid.
Percentile is the rank of today's reading within ~3 years of this symbol's own history. High percentile = wings are rich relative to history; not a directional signal. Skew is read off the chain in real time, not from CBOE SKEW.
Enter a ticker to render the implied volatility surface.
Enter a ticker to render the implied volatility smile.
Risk Metrics
Analysis Details
Data Points: 251
Period: 252 trading days
High volatility - stock moves more than market
| Investor | Value | Share of their portfolio | Rank | Q/Q shares | Source |
|---|---|---|---|---|---|
| Citadel Hedge fund Ken Griffin | $25.4M | #1017 of 6285 | -9.8% | 13F | |
| Millennium Management Hedge fund Izzy Englander | $20.8M | #1101 of 3716 | +1.3% | 13F | |
| Rockefeller Capital Management Family office Rockefeller family | $5.5M | #931 of 4729 | +38.6% | 13F |
Hedge funds, activists, holding companies and family offices we track, from their latest 13F (quarter-end value) and Form 4 filings in the last 3 years. Family offices · all institutions
CRSP Institutional Ownership (13F)
Latest filings — 2026-09-30Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.
- Shares — long equity positions in this name, aggregated across share classes.
- Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
- % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
- Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.
Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.
| # | Filer | Notional Value | % of Total | Period |
|---|---|---|---|---|
| 1 | Susquehanna International Group, LLP Custodian | $35.53M | 21.10% | 2026-06-30 |
| 2 | Citadel Advisors LLC Custodian | $27.95M | 16.59% | 2026-06-30 |
| 3 | Jane Street Group, LLC Custodian | $25.13M | 14.92% | 2026-06-30 |
| 4 | IMC-Chicago, LLC Custodian | $16.68M | 9.90% | 2026-06-30 |
| 5 | D. E. Shaw & Co., Inc. Custodian | $11.80M | 7.01% | 2026-06-30 |
| 6 | PEAK6 LLC | $7.67M | 4.55% | 2026-06-30 |
| 7 | Millennium Management LLC Custodian | $6.29M | 3.74% | 2026-06-30 |
| 8 | Walleye Trading LLC | $6.01M | 3.57% | 2026-06-30 |
| 9 | Caption Management, LLC | $6.00M | 3.56% | 2026-06-30 |
| 10 | Citigroup Inc. Custodian | $5.56M | 3.30% | 2026-06-30 |
| 11 | Cubist Systematic Strategies, LLC | $4.24M | 2.52% | 2025-09-30 |
| 12 | Point72 Asset Management, L.P. | $2.78M | 1.65% | 2026-06-30 |
| 13 | GROUP ONE TRADING LLC Custodian | $2.49M | 1.48% | 2026-06-30 |
| 14 | TUDOR INVESTMENT CORP ET AL | $2.48M | 1.47% | 2026-06-30 |
| 15 | Simplex Trading, LLC Custodian | $2.12M | 1.26% | 2026-06-30 |
| 16 | Walleye Capital LLC | $2.01M | 1.19% | 2026-06-30 |
| 17 | NOMURA HOLDINGS INC | $1.96M | 1.17% | 2026-06-30 |
| 18 | HUB Investment Partners, LLC | $970.81K | 0.58% | 2026-06-30 |
| 19 | Squarepoint Ops LLC | $458.14K | 0.27% | 2026-06-30 |
| 20 | UBS Group AG Custodian | $272.70K | 0.16% | 2026-06-30 |
| 21 | Arkadios Wealth Advisors | $21.82K | 0.01% | 2026-06-30 |
| # | Filer | Notional Value | % of Total | Period |
|---|---|---|---|---|
| 1 | Susquehanna International Group, LLP Custodian | $36.91M | 21.78% | 2026-06-30 |
| 2 | Citadel Advisors LLC Custodian | $31.64M | 18.67% | 2026-06-30 |
| 3 | PEAK6 LLC | $23.27M | 13.73% | 2026-06-30 |
| 4 | IMC-Chicago, LLC Custodian | $13.84M | 8.17% | 2026-06-30 |
| 5 | SFE Investment Counsel | $12.46M | 7.35% | 2026-06-30 |
| 6 | Jane Street Group, LLC Custodian | $11.70M | 6.90% | 2026-06-30 |
| 7 | Walleye Trading LLC | $7.06M | 4.16% | 2026-06-30 |
| 8 | GROUP ONE TRADING LLC Custodian | $6.56M | 3.87% | 2026-06-30 |
| 9 | Citigroup Inc. Custodian | $5.56M | 3.28% | 2026-06-30 |
| 10 | WOLVERINE ASSET MANAGEMENT LLC | $5.45M | 3.22% | 2026-06-30 |
| 11 | Jain Global LLC | $2.37M | 1.40% | 2026-06-30 |
| 12 | Simplex Trading, LLC Custodian | $1.97M | 1.16% | 2026-06-30 |
| 13 | NOMURA HOLDINGS INC | $1.96M | 1.16% | 2026-06-30 |
| 14 | Point72 Asset Management, L.P. | $1.92M | 1.13% | 2026-06-30 |
| 15 | TUDOR INVESTMENT CORP ET AL | $1.75M | 1.03% | 2026-06-30 |
| 16 | Caption Management, LLC | $1.64M | 0.97% | 2026-06-30 |
| 17 | Cubist Systematic Strategies, LLC | $1.45M | 0.86% | 2025-09-30 |
| 18 | Walleye Capital LLC | $1.33M | 0.79% | 2026-06-30 |
| 19 | D. E. Shaw & Co., Inc. Custodian | $665.39K | 0.39% | 2026-06-30 |
CRSP Insider Trading (Form 4)
Latest: 2026-10-21| Filed | Reporter | Role | Action | Shares | Avg Price | Net $ | Link |
|---|---|---|---|---|---|---|---|
| 2026-10-21 | Andrew Jacob Silver | Chief Financial Officer | Grant (A) | +25,000 RSU | — | EDGAR | |
| 2026-10-20 | Samarth Kulkarni | Chief Executive Officer | Mixed | +52,163 | $49.78 | -$2.38M | EDGAR |
| 2026-10-16 | Simeon George | Director | Mixed | +15,486 | $25.62 | -$300.4K | EDGAR |
| 2026-10-15 | Samarth Kulkarni | Chief Executive Officer | Mixed | +4,235 | $49.26 | -$201.9K | EDGAR |
| 2026-10-15 | James R. Kasinger | General Counsel and Secretary | Mixed | +1,073 | $49.26 | -$51.2K | EDGAR |
| 2026-10-08 | James R. Kasinger | General Counsel and Secretary | Mixed | — | $36.83 | -$92.4K | EDGAR |
| 2026-09-24 | James R. Kasinger | General Counsel and Secretary | Mixed | — | $36.93 | -$484.8K | EDGAR |
| 2026-09-21 | Ali Behbahani | Director | Other (J) | +75 | — | EDGAR | |
| 2026-09-21 | Ali Behbahani | Director | Mixed | +16,321 | $27.49 | -$360.9K | EDGAR |
| 2026-08-11 | Raju Prasad | Chief Financial Officer | Gift (G) | −750 | — | EDGAR | |
| 2026-06-09 | Simeon George | Director | Grant (A) | +13,000 opt | — | EDGAR | |
| 2026-06-09 | Sandesh Mahatme | Director | Grant (A) | +13,000 opt | — | EDGAR | |
| 2026-06-09 | Maria Fardis | Director | Grant (A) | +13,000 opt | — | EDGAR | |
| 2026-06-09 | Christian Rommel | Director | Grant (A) | +13,000 opt | — | EDGAR | |
| 2026-06-09 | Katherine A High | Director | Grant (A) | +13,000 opt | — | EDGAR |
CRSP Insider Holdings
9 insiders · @ $51.47| # | Insider | Role | Shares | Disclosed Exposure | Lifetime OM Net | Filings | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Samarth Kulkarni | Chief Executive Officer | 445,358 | $22.92M | -$66.60M | 89 | 2026-10-20 |
| 2 | James R. Kasinger | General Counsel and Secretary | 95,857 | $4.93M | -$8.51M | 41 | 2026-10-15 |
| 3 | Simeon George | Director | 85,173 | $4.38M | $50.78M | 12 | 2026-10-16 |
| 4 | Douglas A Treco | Director | 22,000 | $1.13M | $1.14M | 8 | 2026-06-09 |
| 5 | Naimish Patel | Chief Medical Officer | 19,357 | $996.3K | -$454.2K | 11 | 2026-06-02 |
| 6 | Julianne Bruno | Chief Operating Officer | 19,346 | $995.7K | -$336.1K | 7 | 2025-03-24 |
| 7 | Ali Behbahani | Director | 16,666 | $857.8K | -$780.9K | 13 | 2026-09-21 |
| 8 | Raju Prasad | Chief Financial Officer | 14,815 | $762.5K | -$5.60M | 16 | 2026-08-11 |
| 9 | John Greene | Director | 7,000 | $360.3K | $313.9K | 9 | 2026-06-09 |
CRSP Board & Officers
As of SEC filings through Oct 21, 2026Directors 11
- Ali Behbahani · since Oct 18, 2016
- Simeon George · since Oct 18, 2016
- Samarth Kulkarni · listed since Jun 2018
- John Greene · since Jun 11, 2019
- Katherine A High · since Jun 11, 2019
- Douglas A Treco · since Jun 11, 2020
- Harold Edward Fleming · since Jun 10, 2021
- Maria Fardis · since Jun 9, 2022
- Christian Rommel · since May 30, 2024
- Sandesh Mahatme · since May 30, 2024
- Briggs Morrison · since Jun 5, 2025
Officers 4
- Samarth Kulkarni · Chief Executive Officer · listed since Dec 2017
- Andrew Jacob Silver · Chief Financial Officer · since Oct 19, 2026
- Naimish Patel · Chief Medical Officer · since May 28, 2024
- James R. Kasinger · General Counsel and Secretary · since May 31, 2017
Changes in the last 10 years (36)
| Oct 19, 2026 | The company announced the departure of Raju Prasad as Chief Financial Officer in an SEC filing |
| Oct 19, 2026 | Andrew Jacob Silver became Chief Financial Officer |
| Jun 5, 2025 | Briggs Morrison became a director |
| Mar 24, 2025 | The company announced the departure of Julianne Bruno as Chief Operating Officer in an SEC filing |
| May 30, 2024 | Sandesh Mahatme became a director |
| May 30, 2024 | Christian Rommel became a director |
| May 28, 2024 | Naimish Patel became Chief Medical Officer |
| May 23, 2024 | Julianne Bruno became Chief Operating Officer |
| Dec 14, 2023 | The company announced the departure of Phuong Khanh Morrow as Chief Medical Officer in an SEC filing |
| Mar 28, 2023 | The company announced the departure of Bradley J PhD Bolzon from the board in an SEC filing |
| Mar 14, 2023 | Raju Prasad became Chief Financial Officer |
| Mar 9, 2023 | The company announced the departure of Brendan Smith as Chief Financial Officer in an SEC filing |
| Oct 27, 2022 | The company announced the departure of Lawrence Otto Klein as Cbo & COO in an SEC filing |
| Jun 9, 2022 | Maria Fardis became a director |
| May 23, 2022 | Phuong Khanh Morrow became Chief Medical Officer |
| Dec 14, 2021 | The company announced the departure of Tony W Ho as Executive VP, Head of R&D in an SEC filing |
| Oct 14, 2021 | Brendan Smith became Chief Financial Officer |
| Jun 10, 2021 | Harold Edward Fleming became a director |
| Jun 11, 2020 | Douglas A Treco became a director |
| Mar 12, 2020 | Lawrence Otto Klein listed as Cbo & COO (previously Chief Business Officer) in SEC filings |
| Aug 5, 2019 | Tony W Ho listed as Executive VP, Head of R&D (previously Executive Vice President, Head of Research & Development) in SEC filings |
| Jun 11, 2019 | Katherine A High became a director |
| Jun 11, 2019 | John Greene became a director |
| Jan 2, 2019 | Lawrence Otto Klein became Chief Business Officer |
| Dec 20, 2018 | Vertex Pharmaceuticals Inc / Ma became a 10% owner |
| Dec 20, 2018 | Vertex Pharmaceuticals (Europe) Ltd became a 10% owner |
| Jun 5, 2018 | Samarth Kulkarni first listed as a director in an SEC filing |
| May 21, 2018 | Rodger Novak listed as President (previously Chief Executive Officer) in SEC filings |
| Dec 7, 2017 | Celgene Corp /de/ reported in an SEC filing no longer being a 10% owner |
| Dec 5, 2017 | Samarth Kulkarni listed as Chief Executive Officer (previously Chief Business Officer) in SEC filings |
| Nov 13, 2017 | Michael John Tomsicek became Chief Financial Officer |
| Sep 7, 2017 | Versant Ventures V, LLC first on file as a 10% owner |
| Sep 7, 2017 | Versant Ventures V (Canada), L.P. first on file as a 10% owner |
| Sep 7, 2017 | Versant Ventures IV, LLC first on file as a 10% owner |
| Aug 1, 2017 | Tony W Ho became Executive Vice President, Head of Research & Development |
| May 31, 2017 | James R. Kasinger became General Counsel and Secretary |
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Not reported recently (22)
- Rodger Novak · Last reported as a director in an SEC filing dated Jun 8, 2023
- Michael John Tomsicek · Last reported as Chief Financial Officer in an SEC filing dated Aug 10, 2021
- Pablo J Cagnoni · Last reported as a director in an SEC filing dated Nov 21, 2019
- Kurt Von Emster · Last reported as a director in an SEC filing dated Jan 18, 2019
- Vertex Pharmaceuticals Inc / Ma · Last reported as a 10% owner in an SEC filing dated Dec 28, 2018
- Vertex Pharmaceuticals (Europe) Ltd · Last reported as a 10% owner in an SEC filing dated Dec 28, 2018
- Thomas Woiwode · Last reported as a director in an SEC filing dated Jun 15, 2018
- Versant Ophthalmic Affiliates I, L.P. · Last reported as a 10% owner in an SEC filing dated Apr 26, 2018
- Versant Venture Capital V, L.P. · Last reported as a 10% owner in an SEC filing dated Apr 26, 2018
- Versant Venture Capital V (Canada), LP · Last reported as a 10% owner in an SEC filing dated Apr 26, 2018
- Versant Affiliates Fund V, L.P. · Last reported as a 10% owner in an SEC filing dated Apr 26, 2018
- Versant Ventures V, LLC · Last reported as a 10% owner in an SEC filing dated Apr 26, 2018
- Versant Venture Capital IV, L.P. · Last reported as a 10% owner in an SEC filing dated Apr 24, 2018
- Versant Side Fund IV, L.P. · Last reported as a 10% owner in an SEC filing dated Apr 24, 2018
- Versant Ventures IV, LLC · Last reported as a 10% owner in an SEC filing dated Apr 24, 2018
- Bayer Global Investments B.V. · Last reported as a 10% owner in an SEC filing dated Jan 30, 2018
- Aktiengesellschaft Bayer · Last reported as a 10% owner in an SEC filing dated Jan 30, 2018
- Tyler Dylan-Hyde · Last reported as Chief Legal Officer in an SEC filing dated Jan 18, 2018
- Versant Ventures V (Canada), L.P. · Last reported as a 10% owner in an SEC filing dated Sep 7, 2017
- Kala Subramanian · Last reported as Senior Vice President, Strategic Development and Operations in an SEC filing dated Jun 19, 2017
- N Anthony Coles · Last reported as a director in an SEC filing dated Jun 2, 2017
- Sven Ante Lundberg · Last reported as Chief Scientific Officer in an SEC filing dated Feb 10, 2017
CRSP Proposed Insider Sales (Form 144)
Latest: 2026-10-14What is Form 144? A notice of intent to sell restricted or control stock under Rule 144. Affiliates (officers, directors, 10%+ owners) and holders of restricted shares must file Form 144 when planning to sell more than 5,000 shares or $50,000 in any 3-month rolling window.
How it relates to Form 4: Form 144 is filed before the trade (up to 90 days in advance); Form 4 is filed within 2 business days after the trade executes. Not every Form 144 results in a sale — the filer may cancel or delay. Look for the corresponding Form 4 on the Insider Activity card to confirm a sale actually happened.
10b5-1 plans: Trades made under a pre-scheduled Rule 10b5-1 plan are not discretionary — they execute automatically on dates set months earlier, regardless of news. High 10b5-1 percentages mean less per-filing signal value, though cumulative selling volume still matters.
"Notice value": Aggregate market value the filer wrote into the Form 144 — i.e. the size of the planned sale, not necessarily the executed dollars. An amended notice (Form 144/A) replaces the original it amends, and cancelled notices are dropped, so neither is double-counted above. A filed value that is clearly inconsistent with the share count at the stock's price (a filer typo) shows as a dash and is left out of the totals.
Source & freshness: Sourced from public Form 144 filings. Refreshed daily; new filings typically appear here the morning after they are filed.
| Filed | Filer | Role | Shares | Notice Value | Planned Sale | Broker | Plan | Link |
|---|---|---|---|---|---|---|---|---|
| 2026-10-14 | SIMEON GEORGE | Director | 14,514 | $720.4K | 2026-10-14 | Morgan Stanley Smith Barney LLC … | — | EDGAR |
| 2026-10-06 | JAMES KASINGER | Officer | 1,990 | $119.5K | 2026-10-06 | Morgan Stanley Smith Barney LLC … | 10b5-1 | EDGAR |
| 2026-09-22 | JAMES KASINGER | Officer | 10,400 | $626.5K | 2026-09-22 | Morgan Stanley Smith Barney LLC … | 10b5-1 | EDGAR |
| 2026-09-17 | ALI BEHBAHANI | Director | 13,679 | $780.9K | 2026-09-17 | Morgan Stanley Smith Barney LLC … | — | EDGAR |
| 2026-01-22 | Samarth Kulkarni | Officer | 60,000 | $3.65M | 2026-01-22 | Goldman Sachs & Co. LLC | 10b5-1 | EDGAR |
| 2026-01-22 | RAJU PRASAD | Officer | 34,972 | $2.11M | 2026-01-22 | Morgan Stanley Smith Barney LLC … | 10b5-1 | EDGAR |
| 2026-01-20 | Samarth Kulkarni | Officer | 30,000 | $1.58M | 2026-01-20 | Goldman Sachs & Co. LLC | 10b5-1 | EDGAR |
| 2026-01-06 | RAJU PRASAD | Officer | 29,700 | $1.79M | 2026-01-06 | Morgan Stanley Smith Barney LLC … | 10b5-1 | EDGAR |
| 2025-12-22 | RAJU PRASAD | Officer | 10,000 | $559.5K | 2025-12-22 | Morgan Stanley Smith Barney LLC … | 10b5-1 | EDGAR |
| 2025-02-18 | Samarth Kulkarni | Officer | 45,000 | $2.35M | 2025-02-18 | Goldman Sachs & Co. LLC | 10b5-1 | EDGAR |
| # | ETF | Provider | Weight | $ Exposure | ETF AUM | As Of |
|---|---|---|---|---|---|---|
| 1 | XBI State Street® SPDR® S&P® Biotech ETF | SPDR (State Street) | 1.37% | $142.3M | $10.4B | 2026-10-23 |
| 2 | IWM iShares Russell 2000 ETF | iShares (BlackRock) | 0.15% | $111.4M | $74.6B | 2026-10-23 |
| 3 | VXF Vanguard Extended Market ETF | Vanguard | 0.06% | $60.5M | — | 2026-09-30 |
| 4 | IWN iShares Russell 2000 Value ETF | iShares (BlackRock) | 0.26% | $35.7M | $13.9B | 2026-10-23 |
| 5 | IBB iShares Biotechnology ETF | iShares (BlackRock) | 0.32% | $33.7M | $10.7B | 2026-10-23 |
| 6 | VTWO Vanguard Russell 2000 ETF | Vanguard | 0.16% | $28.9M | — | 2026-09-30 |
| 7 | AVSC Avantis U.S. Small Cap Equity ETF | Avantis | 0.24% | $7.6M | $3.2B | 2026-10-23 |
| 8 | ITOT iShares Core S&P Total U.S. Stock Market ETF | iShares (BlackRock) | 0.01% | $6.4M | $96.5B | 2026-10-23 |
| 9 | LABU Direxion Daily S&P Biotech Bull 3X ETF | Direxion | 0.96% | $5.5M | — | 2026-10-26 |
| 10 | IWO iShares Russell 2000 Growth ETF | iShares (BlackRock) | 0.04% | $5.5M | $13.7B | 2026-10-23 |
| 11 | FESM Fidelity Enhanced Small Cap Core ETF | Fidelity | 0.07% | $4.4M | $6.6B | 2026-10-23 |
| 12 | VT Vanguard Total World Stock ETF | Vanguard | 0.00% | $4.3M | — | 2026-09-30 |
| 13 | IDNA iShares Genomics Immunology and Healthcare ETF | iShares (BlackRock) | 1.28% | $4.1M | $321.2M | 2026-10-23 |
| 14 | VTWV Vanguard Russell 2000 Value ETF | Vanguard | 0.29% | $4.0M | — | 2026-09-30 |
| 15 | SMLF iShares U.S. Small-Cap Equity Factor ETF | iShares (BlackRock) | 0.08% | $3.5M | $4.2B | 2026-10-23 |
| 16 | GNOM Global X Genomics & Biotechnology ETF | Global X | 2.50% | $2.7M | — | 2026-10-26 |
| 17 | KOMP State Street® SPDR® S&P Kensho New Economies Composite ETF | SPDR (State Street) | 0.10% | $2.4M | $2.5B | 2026-10-23 |
| 18 | RSSL Global X Russell 2000 ETF | Global X | 0.15% | $2.1M | — | 2026-10-26 |
| 19 | FHLC Fidelity MSCI Health Care Index ETF | Fidelity | 0.06% | $2.1M | $3.8B | 2026-10-23 |
| 20 | ESML iShares ESG Aware MSCI USA Small-Cap ETF | iShares (BlackRock) | 0.06% | $1.7M | $2.7B | 2026-10-23 |
| 21 | NXTE AXS Green Alpha ETF | Nport | 2.81% | $1.6M | — | 2026-06-30 |
| 22 | JHSC John Hancock Multifactor Small Cap ETF | Nport | 0.21% | $1.4M | — | 2026-06-30 |
| 23 | BBSC JPMorgan BetaBuilders U.S. Small Cap Equity ETF | JPMorgan | 0.19% | $1.4M | $734.0M | 2026-10-26 |
| 24 | ONEQ Fidelity Nasdaq Composite Index ETF | Fidelity | 0.01% | $1.4M | $10.7B | 2026-10-23 |
| 25 | IWV iShares Russell 3000 ETF | iShares (BlackRock) | 0.01% | $1.3M | $20.4B | 2026-10-23 |
Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.
- Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
- Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
- Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
- Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
- Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
- YoY growth — compare to the same quarter a year earlier to remove seasonality.
- Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
- Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.
TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.
Quarterly figures (12 quarters)
| Quarter | Period End | Revenue | Net Income | Diluted EPS | Op. Cash Flow |
|---|---|---|---|---|---|
| Q1 '26 | 2026-03-31 | $1.46M | $-122.93M | $-1.28 | $-108.90M |
| Q4 '25 | 2025-12-31 | $864.00K | $-130.61M | $-1.35 | $-92.55M |
| Q3 '25 | 2025-09-30 | $889.00K | $-106.44M | $-1.17 | $-84.63M |
| Q2 '25 | 2025-06-30 | $892.00K | $-208.55M | $-2.40 | $-113.88M |
| Q1 '25 | 2025-03-31 | $865.00K | $-136.00M | $-1.58 | $-53.95M |
| Q4 '24 | 2024-12-31 | $35.69M | $-37.31M | $-0.42 | $-50.03M |
| Q3 '24 | 2024-09-30 | $602.00K | $-85.94M | $-1.01 | $-106.91M |
| Q2 '24 | 2024-06-30 | $517.00K | $-126.41M | $-1.49 | $-95.58M |
| Q1 '24 | 2024-03-31 | $504.00K | $-116.59M | $-1.43 | $109.75M |
| Q4 '23 | 2023-12-31 | $201.21M | $89.35M | $1.13 | $-93.57M |
| Q3 '23 | 2023-09-30 | — | $-112.15M | $-1.41 | $-40.86M |
| Q2 '23 | 2023-06-30 | $70.00M | $-77.74M | $-0.98 | $-134.75M |
Ratios derived from TTM financials and the current market price, sampled daily. History chart shows how expensive the stock is today relative to its own recent past.
- P/E — price / TTM earnings. Rough market rule: 10–15 value, 15–25 market, >30 growth/premium. Negative when earnings are negative.
- P/B — price / book value. Useful for financials and asset-heavy names; meaningless for asset-light software.
- P/S — price / TTM revenue. Useful when earnings are negative or noisy (early-stage growth).
- EV/EBITDA — capital-structure-neutral. <10 cheap, 10–15 reasonable, >20 rich. Good for comparing across leverage profiles.
- EV/Sales — like P/S but accounts for debt + cash. Compare within sector.
- ROE — return on equity. >15% strong, >25% exceptional. Caution: high leverage inflates ROE.
- ROA — return on assets. Leverage-neutral; >5% solid, >10% exceptional.
- Div Yield — annual dividend / price. Compare to 10Y Treasury; sustained yield >6% often signals distress.
- FCF Yield — free cash flow / market cap. >5% is attractive; negative means burning cash.
- Debt/Equity — leverage. <1 conservative, >2 aggressive. Sector-dependent (utilities naturally high, tech low).
- Current Ratio — short-term liquidity. >1.5 comfortable, <1 raises short-term solvency flags.
- Compare current level to the 3-year band: near the high end = relatively expensive; near the low = relatively cheap.
- Multiples expanding while earnings are flat = sentiment-driven rally.
- Multiples compressing while earnings grow = value coming from fundamentals.
Regulatory short-interest reports publish on a bi-weekly settlement cadence; short-volume is reported daily by the trade-reporting facilities. Float is derived from insider-ownership filings.
- Short Interest — total shares currently sold short as of the settlement date. Lags real time by ~8 business days.
- SI % of Float — short interest / free float. The key crowding metric.
- Days to Cover — short interest / avg daily volume. How many full trading days it would take shorts to buy back. High DTC + catalyst = squeeze fuel.
- Short Vol Ratio — today's short-sale volume / total volume. Intraday selling pressure proxy (not the same as short interest).
- Free Float — shares available for public trading (total shares minus insider / restricted).
- Float % — free float / shares outstanding. <50% = tightly held, more prone to squeezes.
- SI % of Float < 5% — typical, no particular signal.
- 5–15% — elevated; watch for catalysts (earnings, guidance, macro).
- 15–30% — heavily shorted; tight-float names in this range have produced notable squeezes historically.
- >30% — extreme; borrow is likely expensive and squeeze risk is material.
- Days to Cover > 5 combined with high SI% amplifies squeeze potential.
- Trend matters more than level. Rapidly rising short interest often precedes negative catalysts or heavy hedging.
- A sudden drop in SI after a rally may indicate a squeeze in progress.
Short interest is reported mid-month and end-of-month; short volume is daily.