Simeon George
CIK 1595117 · last filed 2026-10-16
Simeon George is a corporate insider who has filed 51 SEC Form 4 insider transactions across 12 companies since 2014. The most recent filing, for CRSP, was dated Oct 16, 2026. Across all open-market trades the lifetime net is +$432.6M, making them a net buyer over the disclosed history. Current disclosed insider exposure totals $143.7M across reported positions. 12 SEC filings were submitted jointly with SR ONE CAPITAL MANAGEMENT, LLC.
"Disclosed insider exposure" sums this person's most-recently-reported share counts across each company they're an insider in, multiplied by the current underlying price. It is not net worth — it misses retail holdings, private investments, real estate, index funds, and any company where the person isn't an SEC-reporting insider. For informational purposes only.
Charts
Trading activity, where the exposure sits, and each trade against the stock price.
ACLX price and trades
Daily close with each Form 4 filing on this company marked: green = open-market buy, red = open-market sale, purple = grants, exercises, gifts and other non-market transactions. Marker size scales with the dollar value.
Shares held
Shares owned after each reported transaction on this company (direct holdings as reported).
Open-market buying and selling
by monthDollar value of open-market purchases (code P, up) and sales (code S, down) across all companies, by filing month. Grants, exercises and gifts are excluded.
Exposure by company
latestMost recently reported shares × current price. Faded bars (*) have had no filing in 3 years, so the person may no longer hold them. Click a bar to chart that company.
Filer Profile
929 MAIN STREET, SUITE 200
REDWOOD CITY, CA 94063
Holdings By Company
| Symbol | Role | Shares | Price | Disclosed Exposure | Lifetime OM Net | Filings | Latest Filed |
|---|---|---|---|---|---|---|---|
| CRSP | Director | 85,173 | $51.47 | $4.38M | $50.78M | 12 | 2026-10-16 |
| ADRX | Director | 1,953,505 | — | — | $27.20M | 1 | 2026-09-29 |
| NKTX | Director | 666,667 | $1.70 | $1.13M | $40.00M | 9 | 2026-06-11 |
| DSGN | Director | 6,486,476 | $10.63 | $68.95M | $12.57M | 8 | 2026-06-11 |
| ODTX | 10%+ Owner | 734,868 | $19.50 | $14.33M | $19.94M | 1 | 2026-05-11 |
| AVLN | 10%+ Owner | 1,419,298 | $25.83 | $36.66M | $20.00M | 1 | 2026-05-01 |
| ZBIO | 10%+ Owner | 669,061 | $27.30 | $18.27M | $76.00M | 1 | 2024-09-16 |
| Turning Point Therapeutics, Inc. (TPTX) Delisted | Director | 0 | $76.01 | $0 | $18.85M | 6 | 2022-08-17 |
| Arcellx, Inc. (ACLX) Delisted | 10%+ Owner | 2,216,960 | $115.07 | $255.11M | $150.00M | 1 | 2022-02-10 |
| Principia Biopharma Inc. (PRNB) Delisted | Director | 0 | — | — | $14.59M | 6 | 2020-09-28 |
| CRISPR Therapeutics AG (PZRX) Delisted | Director | 3,220,627 | — | — | $931.0K | 3 | 2017-06-02 |
| GENOCEA BIOSCIENCES, INC. (GNCA) Delisted | Director | 114,933 | $0.00 | $69 | $1.73M | 1 | 2014-02-11 |
Recent Filings
51 filings| Filed | Symbol | Action | Net Shares | Net $ | Link |
|---|---|---|---|---|---|
| 2026-10-16 | CRSP | Mixed | +15,486 | -$300.4K | EDGAR |
| 2026-10-14 | CRSP | Notice (144) | −14,514 | -$720.4K | EDGAR |
| 2026-09-29 | ADRX | Mixed | +9,936,661 | $27.20M | EDGAR |
| 2026-06-11 | DSGN | Grant (A) | — | $0 | EDGAR |
| 2026-06-11 | NKTX | Grant (A) | — | $0 | EDGAR |
| 2026-06-09 | CRSP | Grant (A) | — | $0 | EDGAR |
| 2026-05-11 | ODTX | Mixed | +7,589,766 | $19.94M | EDGAR |
| 2026-05-01 | AVLN | Mixed | +6,617,298 | $20.00M | EDGAR |
| 2025-07-17 | CRSP | Buy (P) | +989,812 | $51.50M | EDGAR |
| 2025-06-12 | DSGN | Grant (A) | — | $0 | EDGAR |
Notice (144 / 144/A): Form 144 is a notice of intent to sell restricted/control stock under Rule 144, filed before the sale; 144/A is an amendment. Many notices are pre-scheduled under Rule 10b5-1 plans. A Form 4 with code S typically follows within a few days when the planned sale executes; missing follow-up Form 4s suggest the notice was cancelled or modified.