New Leaf Venture Partners, L.L.C. — 13F Holdings & Portfolio

CIK 1631614 · latest 13F-HR filed 2025-11-14

AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.

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AUM

$43.0M

Long-equity book

Holdings

7

Distinct positions

Period

2025-09-30

Filed 2025-11-14

Q/Q Activity

+0 / −1 / ↑6 / ↓1

vs 2025-06-30

Firm Profile & Key People
Name Title / Status Ownership Type

Top Adds (vs prior quarter)

  • EWTX$3.2M +23.7%
  • ARVN$1.8M +15.8%
  • CRNX$1.8M +44.8%
  • COGT$1.8M +100.0%
  • RLYB$531.6K +47.6%
Show all 6

Top Trims

  • PASG-$19.3M -96.5%
Show all 1

New Positions

  • No new positions this quarter.
Show all 0

Exited Positions

  • ITERUM THERAPEUTICS PLC$343.3K
Show all 1
All Holdings

Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).

# Issuer Symbol CUSIP Value Weight Shares Type
1 EWTX EWTX 28036F105 $16.7M 38.82% 1,030,161 SH
2 ARVN ARVN 04335A105 $13.5M 31.38% 1,585,721 SH
3 CRNX CRNX 22663K107 $5.9M 13.64% 141,000 SH
4 COGT COGT 19240Q201 $3.6M 8.37% 250,765 SH
5 RLYB RLYB 75120L100 $1.6M 3.83% 3,301,603 SH
6 ALEC ALEC 014442107 $1.0M 2.33% 339,569 SH
7 PASG 702712100 $702.0K 1.63% 87,426 SH
Filing History
Period Filed AUM Holdings Accession
2025-09-30 2025-11-14 $43.0M 7 0001193125-25-280589
2025-06-30 2025-08-13 $52.9M 8 0000950123-25-007852