Omega Fund Management, LLC — 13F Holdings & Portfolio

CIK 1637359 · latest 13F-HR filed 2026-05-15

Omega Fund Management, LLC manages $163.1M in 13F-reported U.S. long-equity assets across 10 reported positions as of its 2026-03-31 13F-HR filing. Its largest disclosed positions are BCAX (29.16%), NUVB (21.25%), BBOT (18.05%). Quarter over quarter (versus its 2025-12-31 filing) the fund opened 0 new positions, exited 1, added to 1, and trimmed 9.

AUM is the long-equity portion reported on Form 13F-HR. Excludes short positions, cash, foreign holdings, and non-13F assets. For informational purposes only — not investment advice.

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AUM

$163.1M

Long-equity book

Holdings

10

Distinct positions

Period

2026-03-31

Filed 2026-05-15

Q/Q Activity

+0 / −1 / ↑1 / ↓9

vs 2025-12-31

Firm Profile & Key People
Name Title / Status Ownership Type

Top Adds (vs prior quarter)

  • Bicara Therapeutics Inc.$10.5M +28.2%
Show all 1

Top Trims

  • Nuvation Bio Inc.-$37.7M -52.1%
  • Beta Bionics Inc.-$26.9M -67.1%
  • Kestra Med Technologies Ltd-$16.1M -44.1%
  • BridgeBio Oncology Therapeutics Inc.-$11.7M -28.5%
  • enGene Holdings Inc.-$1.9M -24.6%
Show all 9

New Positions

  • No new positions this quarter.
Show all 0

Exited Positions

  • Upstream Bio Inc.$36.0M
Show all 1
All Holdings

Rows tagged Call or Put are options positions, not stock. Per SEC Form 13F-HR, Value shows the notional value of the underlying (shares covered × underlying price), not the option premium. Shares is the number of underlying shares covered (divide by 100 for contract count).

# Issuer Symbol CUSIP Value Weight Shares Type
1 Bicara Therapeutics Inc. BCAX 055477103 $47.6M 29.16% 2,392,150 SH
2 Nuvation Bio Inc. NUVB 67080N101 $34.7M 21.25% 8,081,089 SH
3 BridgeBio Oncology Therapeutics Inc. BBOT 107924102 $29.4M 18.05% 3,289,661 SH
4 Kestra Med Technologies Ltd KMTS G52441105 $20.4M 12.49% 1,022,149 SH
5 Beta Bionics Inc. BBNX 08659B102 $13.2M 8.08% 1,316,183 SH
6 enGene Holdings Inc. ENGNW 29286M105 $6.0M 3.66% 876,357 SH
7 Alumis Inc. ALMS 022307102 $5.3M 3.26% 241,255 SH
8 Sana Biotechnology, Inc. SANA 799566104 $2.4M 1.49% 843,750 SH
9 ImageneBio, Inc. IMA 45175G207 $2.3M 1.40% 455,361 SH
10 Replimune Group REPL 76029N106 $1.9M 1.17% 248,672 SH
Filing History
Period Filed AUM Holdings Accession
2026-03-31 2026-05-15 $163.1M 10 0001193125-26-225480
2025-12-31 2026-02-17 $286.5M 11 0001193125-26-053268
2025-09-30 2025-11-14 $222.4M 12 0001193125-25-281790