Nuvation Bio Inc.(NUVB)

Stock quote, options chain, IV rank, technicals, AI analysis, and institutional ownership.

Market data may be delayed, incomplete, or inaccurate. Not a recommendation to buy, sell, or hold any security. Verify quotes with your broker before trading. See Terms §17.

Snapshot
$4.96
52-Week Range
$1.57 – $9.75
YTD
-42.19%
IV Rank (30D)
7.55
Straddle Price
$1.00
P/C Vol Ratio
0.19
Market Cap
$1.7B
Fair Value
+22.8% vs price
Confidence: 13% Alpha Score: 0.43

A blended fair-value estimate combining up to six valuation methods. Each method is weighted by how well it fits the company — DCF down-weights for unprofitable names; DDM only fires for steady dividend payers; comparables down-weight when peer multiples disagree.

  • DCF (quality-aware) — projects free cash flow with a horizon that scales to business quality. True compounders (quality 6/6) get 10 years explicit + 10 years fade before terminal; cyclical/struggling names (quality 0-1) get a 5-year terminal cliff. Quality is scored from ROE, gross margin, growth, FCF margin, debt load, and FCF consistency — the same factors that drive market premium for compounders.
  • Market-Implied Growth (in Model Inputs) — reverse-DCF that answers "what growth rate is the market pricing in?". Lets you sanity-check the deviation: if implied growth is plausible for the business, the model's bearish flag may be wrong; if implausible, the market may be over-extrapolating.
  • DDM (Gordon Growth Dividend Model) — values the stream of future dividends. Only used when trailing yield ≥ 0.5% and dividend payments are stable.
  • P/E, EV/EBITDA, P/B, P/S — applies the peer-group median multiple to this company's per-share metric. Peers come from the same set as the "Related symbols" card. Earnings/sales metrics are forward-tilted by the company's recent revenue growth (capped at 25%) so they're comparable to peers' growth-embedded multiples — mimics how analysts use NTM rather than TTM. Per-multiple weights are biased by company quality (e.g. P/B down-weighted for asset-light tech).
  • Market Anchor (SMA50) — the 50-day moving average, weighted by recent trading-range stability (tighter Bollinger bands → higher weight). Captures information fundamentals miss (forward consensus, sentiment, supply/demand) — but only when recent trading is steady enough that the market has converged on a view. During wild breakouts or breakdowns the anchor's weight collapses.
  • Options Expected (B-L 30d) — the risk-neutral expected stock price at 30-day options expiration, derived from the full implied-volatility surface via Breeden-Litzenberger (second derivative of call price wrt strike → implied PDF, then E[S_T]). Forward-looking, captures all options-implied information (smile, skew, term structure) in one number. Weighted by chain liquidity. SP500-only at present (pre-computed daily). Backtest evidence: adds modest alpha across most bucket × holding combos.
  • Blended value — weighted average. Confidence reflects how many methods fired and how tight peer dispersion is.
  • Deviation pill — green when blended FV ≥ 10% above current price (undervalued); red when ≥ 10% below; grey otherwise.
10-yr Treasury (rf)4.53%
Beta vs SPY1.00
Cost of Equity (CAPM)10.03% (VRP-adj)
WACC9.86%
Volatility Risk Premium+62.3pp (IV − HV30), ERP adj +50bps
Effective Tax Rate21.0%
Rev. Growth (YoY, DCF input)+30.0%
DCF Horizon10 years explicit + fade
Forward Tilt (NTM/TTM)×1.10 (applied to P/E, EV/EBITDA, P/S)
Free Cash Flow (TTM)$-0.1B
Return on Equity (TTM)-45.7%
Book / Price19.2%
Gross Margin (TTM)91.6%
FCF Margin (TTM)-93.7%
Debt / Equity0.15
Quality Score3/6 — normal (10y DCF)
SMA 50$4.72 (Market Anchor value)
SMA 20 / Bollinger Mid$4.71
Bollinger Width / SMA20418.9% (drives anchor stability)
Net Debt$-0.1B
Market Cap$2B
Peers used for multiples: AXSM, CORT, DFTX, EWTX, JAZZ, LQDA, OGN, RPRX
Blended Fair Value
$6.04
Current Price
$4.92
Deviation
+22.8%
Forward-Return Rank LONG gates ✓
?
Horizon Expected α z Pred Blended z Rank % Active?
21d +1.1% +1.24 +0.92 74.1%
42d +0.8% +1.25 +0.92 71.0%
63d +2.9% +1.40 +1.00 74.2%
Expected α = forward-return point estimate vs SPY (e.g., +7.5% means the predictor expects this stock to outperform SPY by 7.5% over that horizon). For SHORT direction the model uses a different ranking metric (conviction-weighted deviation, not the LGBM prediction); Expected α is shown for reference. flags rows where Expected α disagrees with the FV direction — two independent signals are in conflict; conviction is low even if rank looks extreme.
Forward-Return Rank. A proprietary ensemble of a machine-learning forward-return model and a conviction-weighted fundamental score, ranked cross-sectionally each day across the S&P 500 (and broader universes on the screener). Each stock is scored at three horizons (21/42/63 trading days). "Active" = top/bottom 5% AND all risk filters pass. Backtested mean alpha vs SPY on active picks: 21d LONG +13.4%, 63d +34.9% (S&P 500, walk-forward). Past performance is not indicative of future results.
Value vs momentum conflict ⚠. The "FV direction" (long/short) comes from the fundamentals-based engine — price vs intrinsic value. The "Expected α" comes from a separate machine-learning predictor trained on ~12 features (sector, options-implied move, beta, institutional flow, etc.). Sometimes the two disagree: a stock is overvalued by fundamentals but the predictor expects it to keep outperforming (sector or momentum tailwinds). When all 3 horizons disagree, treat the direction signal as low-conviction — neither model is strongly recommending a position.
MethodImplied PriceWeightDetail
DCF n/a 0%
DDM (Gordon) n/a 0%
Peer P/E n/a 0% median 181.9× · 5 peers
Peer EV/EBITDA n/a 0% median 17.0× · 4 peers
Peer P/B $7.42 50% median 8.1× · 8 peers
Peer P/S $4.67 50% median 10.4× · 6 peers
Market Anchor (SMA50) $4.72 0% stability 0% (BB-width)
Options Expected (B-L 30d) n/a 0%
As of 2026-06-12 · updated 2026-06-12 20:59:55.687000
Info
Industry (SIC)
PHARMACEUTICAL PREPARATIONS (2834)
Exchange
XNYS
Market Cap
$1.7B

Nuvation Bio Inc is a biopharmaceutical company tackling unmet needs in oncology by developing differentiated and novel therapeutic candidates. Its product candidate, taletrectinib, is an oral, potent, central nervous system-active, selective, next-generation c-ros oncogene 1 (ROS1) inhibitor designed for the treatment of patients with ROS1+ non-small cell lung cancer (NSCLC). In addition, its clinical-stage pipeline includes oncology product candidates such as Safusidenib, NUV-1511, and NUV-868 in different stages of development. The Company generates revenue from out-licensing collaborative …

Price History
Seasonality
MonthAvg ReturnYears of Data
Jan -7.30% 5
Feb -3.70% 6
Mar +10.45% 6
Apr +0.58% 6
May -1.02% 6
Jun -4.84% 6
Jul +5.44% 5
Aug -0.80% 5
Sep -12.04% 5
Oct -0.46% 5
Nov +17.52% 5
Dec -0.99% 5
Technical Indicators

Quick-reference for reading the values below. Indicators combine to confirm a view — no single one is a trade signal on its own.

Trend Indicators
  • SMA 20 / 50 / 200 — price above = uptrend, below = downtrend. SMA 50 crossing SMA 200 is the golden/death cross.
  • EMA 12 / 26 — faster-reacting averages; 12 above 26 is short-term bullish.
  • MACD — bullish when MACD > signal (green badge), bearish when below. Divergence from price often precedes reversals.
  • ADX (14) — trend strength regardless of direction. <20 range, 20–25 weak trend, 25–50 trend, >50 strong trend.
  • +DI / −DI — +DI > −DI favors bulls; the reverse favors bears. Read alongside ADX.
Momentum Oscillators
  • RSI (14) — <30 oversold, >70 overbought. 40–60 is neutral; trending names can stay extreme.
  • Stochastic %K / %D — <20 oversold, >80 overbought. %K crossing %D is an early momentum signal.
  • Williams %R — inverted scale: <−80 oversold, >−20 overbought.

Oscillators work best in range-bound markets; in strong trends they give premature reversal signals.

Volume & Volatility
  • Bollinger Bands — price at upper band = overbought, lower = oversold. Narrow bands (squeeze) often precede expansion.
  • OBV — cumulative volume; rising OBV confirms uptrend, falling OBV confirms downtrend. Divergence from price is a warning.
  • Vol SMA 20 / Vol ROC — today's volume vs. 20-day average. Positive ROC with price move = conviction.
  • ATR / True Range — average daily $ move; sizing and stop-loss reference.
  • HV 20 / 30 / 60 — realized (historical) volatility. Compare to IV on the options cards: IV > HV = rich premium.

Confluence matters: trend + momentum + volume agreeing carries far more weight than any single indicator. For how these feed the spread scanner score, see the algorithm docs →

Trend Indicators
SMA 20: $4.72
SMA 50: $4.73
SMA 200: $5.27
Current: $4.92
EMA 12: $4.81
EMA 26: $4.77
MACD: 0.0398 | Signal: 0.0035
BULLISH
ADX (14): 28.00
TREND
+DI: 35.80
−DI: 10.05
Momentum Oscillators
RSI (14): 53.71
NEUTRAL
Stoch %K: 27.79
Stoch %D: 33.14
Williams %R: -60.50
Volume & Volatility
BB Upper: $5.19
BB Lower: $4.24
NEUTRAL
OBV: 47,099,605
Vol SMA 20: 4,668,794
Vol ROC: 24.92%
ATR: $0.38
True Range: $0.45
HV 20: 73.9%
HV 30: 68.7%
HV 60: 58.8%

Data Summary
Data Points: 500
Last Updated: 2026-06-13T13:41:40.023000
Date Range: 2024-06-14T00:00:00 – 2026-06-12T00:00:00
AI Analysis

Choose Frenzy-Fast™ for quick analysis or Frenzy-Pro™ for comprehensive analysis.

Analysis includes technical indicators, news sentiment, risk assessment, and specific price levels to watch.

Earnings History
8 of 8 under expected move
Each row pairs the pre-earnings straddle-implied expected move with the realized close-to-close move. Sorted oldest first.
Earnings Date Timing Expected Move Actual Move Ratio Outcome
2024-08-05 After-Close 41.14% 3.80% 0.09x Within
2024-11-06 After-Close 27.45% 11.37% 0.41x Within
2025-05-07 After-Close 23.47% 4.00% 0.17x Within
2025-08-07 After-Close 13.89% 1.28% 0.09x Within
2025-11-03 After-Close 23.54% 10.69% 0.45x Within
2026-01-12 After-Close 21.04% 0.69% 0.03x Within
2026-03-02 After-Close 141.71% 29.04% 0.20x Within
2026-05-04 After-Close 18.03% 4.91% 0.27x Within
Options Activity
IV Rank (30D)
7.55
IV Rank (7D)
78.9
Avg IV
132.9%
Straddle (30D)
$1.00
Straddle (7D)
$0.32
P/C Volume
0.19
Spread Scanner GPU

Each spread is ranked by a composite score built in three stages. Full documentation →

Stage 1 — Base Score (GPU scanner)

score = P(profit) × (credit / spread_width)
P(profit) from short leg delta (1 − |delta|), penalised above 85%. Credit uses mid-price to handle illiquid chains fairly.

Stage 2 — Skew Adjustment (±25% cap)

RR25 and BF25 from the live options chain. Put skew boosts bull puts, penalises bear calls. High butterfly boosts iron condors. Calendars are skew-neutral.

Stage 3 — Technical Overlay (±50% cap, 5 groups)
Group 1 · Directional Bias (±0.25)
  • RSI <40 bullish / >60 bearish
  • MACD crossover + histogram trend
  • Price vs SMA 50 & SMA 200
Group 2 · Momentum (±0.10)
  • Stochastic %K <20 / >80
  • Williams %R <−80 / >−20
Group 3 · Volatility (up to −0.25 / +0.15)
  • Blended ATR + straddle expected-move penalty
  • Bollinger Band signal (+ counter-trend penalty)
  • BB width — vol contraction boost for ICs
Group 4 · IV Regime (±0.15)
  • IV rank ≥ 75 → strong boost for credit spreads
  • IV rank < 25 → penalty (selling cheap vol)
Group 5 · Liquidity (penalty up to −0.10)
  • Min open interest across all legs
  • OI < 100 → −0.10 · OI < 500 → −0.05

score = base_score × skew_multiplier × tech_multiplier
Both multipliers are shown per spread. Beta is informational only — ATR already captures realized vol. Full algorithm documentation →

Enter a ticker to scan for optimal spread opportunities.

Evaluates all bull put, bear call, iron condor, and calendar spread combinations using GPU-accelerated analysis.

Volatility Surface

Enter a ticker to render the implied volatility surface.

IV Rank (7 DTE)
IV Rank (30 DTE)
Straddle Price (30 DTE)
Beta Analysis
Beta (1Y vs SPY)
2.24
Correlation (SPY)
30.8%
0.10
Ann. Volatility
89.8%
SPY Volatility
12.3%

High volatility - stock moves more than market

Beta & Alpha Over Time
Institutional Ownership (13F)
Latest filings — 2026-03-31
Diluted shares outstanding: 350,550,250 (as of 2026-03-31)

Institutional managers with $100M+ AUM file Form 13F-HR quarterly, due 45 days after quarter end. Holdings are reported gross at quarter-end market value — they are a snapshot, not a real-time position.

  • Shares — long equity positions in this name, aggregated across share classes.
  • Calls / Puts — notional value of long call / put exposure where this ticker is the underlying.
  • % of Float — holder's reported shares divided by the latest diluted shares outstanding. Sums above 100% indicate large custodian / prime broker positions where the same shares are reported by multiple filers.
  • Custodian badge — filers with more than 5,000 holdings are typically broker-dealers / custodians reporting customer-held shares, not active managers.

Each filer is counted once at its latest 13F-HR filing. New filings are ingested on a weekly cadence.

224 filers219,375,612 shares$985.68M value62.58% of float
# Filer Shares Value % of Total % of Float Period
1 FMR LLC Custodian 51,989,593 $223.04M 22.63% 14.83% 2026-03-31
2 VANGUARD GROUP INC Custodian 15,555,606 $139.38M 14.14% 4.44% 2025-12-31
3 Decheng Capital LLC 25,954,439 $111.34M 11.30% 7.40% 2026-03-31
4 BlackRock, Inc. Custodian 25,100,374 $107.68M 10.92% 7.16% 2026-03-31
5 Omega Fund Management, LLC 8,081,089 $34.67M 3.52% 2.31% 2026-03-31
6 Laurion Capital Management LP 7,822,638 $33.56M 3.40% 2.23% 2026-03-31
7 STATE STREET CORP 6,784,927 $29.11M 2.95% 1.94% 2026-03-31
8 GEODE CAPITAL MANAGEMENT, LLC Custodian 5,863,654 $25.16M 2.55% 1.67% 2026-03-31
9 BANK OF AMERICA CORP /DE/ Custodian 3,219,826 $13.81M 1.40% 0.92% 2026-03-31
10 Redmile Group, LLC 3,153,256 $13.53M 1.37% 0.90% 2026-03-31
11 TANG CAPITAL MANAGEMENT LLC 3,149,557 $13.51M 1.37% 0.90% 2026-03-31
12 AMERICAN CENTURY COMPANIES INC 2,897,078 $12.43M 1.26% 0.83% 2026-03-31
13 TWO SIGMA INVESTMENTS, LP 2,684,089 $11.51M 1.17% 0.77% 2026-03-31
14 MORGAN STANLEY Custodian 1,276,128 $11.43M 1.16% 0.36% 2025-12-31
15 Jones Hill Capital LP 2,383,031 $10.22M 1.04% 0.68% 2026-03-31
16 CITADEL ADVISORS LLC Custodian 2,065,411 $8.86M 0.90% 0.59% 2026-03-31
17 DIMENSIONAL FUND ADVISORS LP Custodian 2,052,691 $8.81M 0.89% 0.59% 2026-03-31
18 Qube Research & Technologies Ltd 2,042,312 $8.76M 0.89% 0.58% 2026-03-31
19 NORTHERN TRUST CORP Custodian 2,003,108 $8.59M 0.87% 0.57% 2026-03-31
20 AQR CAPITAL MANAGEMENT LLC Custodian 1,995,758 $8.56M 0.87% 0.57% 2026-03-31
21 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 1,992,451 $8.55M 0.87% 0.57% 2026-03-31
22 GOLDMAN SACHS GROUP INC Custodian 1,929,953 $8.28M 0.84% 0.55% 2026-03-31
23 ARMISTICE CAPITAL, LLC 1,736,000 $7.45M 0.76% 0.50% 2026-03-31
24 Knoll Capital Management, LLC 1,498,591 $6.43M 0.65% 0.43% 2026-03-31
25 ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 1,439,357 $6.17M 0.63% 0.41% 2026-03-31
4 filers$4.83M notional
# Filer Notional Value % of Total Period
1 Caption Management, LLC $3.43M 71.02% 2026-03-31
2 SUSQUEHANNA INTERNATIONAL GROUP, LLP Custodian $716.00K 14.82% 2026-03-31
3 JANE STREET GROUP, LLC Custodian $366.37K 7.58% 2026-03-31
4 CITADEL ADVISORS LLC Custodian $318.32K 6.59% 2026-03-31
3 filers$2.51M notional
# Filer Notional Value % of Total Period
1 SUSQUEHANNA INTERNATIONAL GROUP, LLP Custodian $982.84K 39.10% 2026-03-31
2 JANE STREET GROUP, LLC Custodian $818.53K 32.57% 2026-03-31
3 CITADEL ADVISORS LLC Custodian $712.14K 28.33% 2026-03-31
Insider Activity
Latest: 2026-06-11
Form 4 filings — insider beneficial-ownership changes by officers, directors, and 10%+ holders. Filed within 2 business days of transaction.
Filed Reporter Role Action Shares Avg Price Net $ Link
2026-06-11 Robert Mashal Director Buy (P) +25,000 $4.73 $118.3K EDGAR
2026-05-26 Robert B Bazemore Director Grant (A) +123,397 opt EDGAR
2026-05-26 Xiangmin Cui Director Grant (A) +76,923 opt EDGAR
2026-05-26 KATHRYN E FALBERG Director Grant (A) +123,397 opt EDGAR
2026-05-26 Xiangmin Cui Director Grant (A) +123,397 opt EDGAR
2026-05-26 W ANTHONY VERNON Director Grant (A) +123,397 opt EDGAR
2026-05-26 Robert Mashal Director Grant (A) +123,397 opt EDGAR
2026-05-26 KIM D BLICKENSTAFF Director Grant (A) +123,397 opt EDGAR
2026-04-21 Kerry Wentworth CHIEF REGULATORY OFFICER Mixed $3.97 -$76.6K EDGAR
2026-04-21 Dongfang Liu CHIEF MEDICAL OFFICER Mixed $3.48 -$154.0K EDGAR
2026-04-08 Kerry Wentworth CHIEF REGULATORY OFFICER Mixed $3.21 -$522.6K EDGAR
2026-03-03 David Hung PRESIDENT AND CEO Grant (A) +1,995,012 opt EDGAR
2026-03-03 Stacy Markel CHIEF PEOPLE OFFICER Award (A) EDGAR
2026-03-03 Dongfang Liu CHIEF MEDICAL OFFICER Grant (A) +748,130 opt EDGAR
2026-03-03 Colleen Sjogren Chief Commercial Officer Award (A) EDGAR
Codes: P = open-market purchase · S = open-market sale · A = grant/award · M = option exercise · F = tax withholding at vest · G = bona-fide gift · D = disposition to issuer · J = other (described in filing footnote — typically 401(k), trust, inheritance) · W = will/inheritance. Only P / S codes carry directional signal.
Insider Holdings
7 insiders · @ $4.92
Officers, directors, and 10%+ owners ranked by current disclosed exposure (shares × today's price). Shares are direct + indirect (via trusts / LLCs / spouse). Excludes unvested RSU and option grants — those aren't beneficially owned until vest.
# Insider Role Shares Disclosed Exposure Lifetime OM Net Filings Last Filed
1 Robert Mashal Director 225,000 $1.11M $118.3K 2 2026-06-11
2 Kerry Wentworth CHIEF REGULATORY OFFICER 89,750 $441.6K -$1.09M 3 2026-04-21
3 Colleen Sjogren Chief Commercial Officer 84,000 $413.3K $0 1 2026-03-03
4 Moses Makunje SEE REMARKS 68,137 $335.2K $0 1 2026-03-03
5 Stacy Markel CHIEF PEOPLE OFFICER 32,591 $160.3K $0 1 2026-03-03
6 Dongfang Liu CHIEF MEDICAL OFFICER 18,000 $88.6K -$251.0K 2 2026-04-21
7 Philippe Sauvage Chief Financial Officer 12,673 $62.4K $0 1 2026-03-03
Lifetime OM Net = signed sum of open-market buys (P) and sells (S) over their career; excludes grants, tax withholdings, and dispositions to issuer. A large negative number is normal for long-tenured executives — they've sold compensation grants over many years.
ETF Holders
# ETF Provider Weight $ Exposure ETF AUM As Of
Fundamentals

Quarterly filings sourced from SEC 10-Q / 10-K reports. TTM tiles aggregate the most recent four quarters; bars show the last ~12 quarters oldest → newest.

Metrics
  • Revenue — top-line sales. Look for consistent YoY growth; seasonal businesses need same-quarter comparisons (Q4 '24 vs Q4 '23).
  • Net Income — bottom-line profit after all expenses. Can be volatile from one-time items; red bars = net loss.
  • Diluted EPS — net income per share assuming options/converts are exercised. Direct input to the P/E ratio.
  • Operating Cash Flow — cash generated from core operations, before capex and financing. Harder to manipulate than net income; growing OCF is a quality signal.
How to read the bars
  • Sequential growth — quarter-over-quarter trend. Accelerating bars are a momentum signal.
  • YoY growth — compare to the same quarter a year earlier to remove seasonality.
  • Quality — OCF should roughly track Net Income over time. Large divergence (net income ≫ OCF) flags accruals risk.
  • Margins — scan the bar ratios: Net Income / Revenue tells you margin trend without needing a separate chart.

TTM (trailing-twelve-month) smooths seasonality and is used for the P/E calculation. Filings appear 30–90 days after the period closes.

P/B Ratio5.2
P/S Ratio11.6
EV/EBITDA-10.7
TTM Revenue$0.1B
TTM Net Income$-0.1B
TTM EPS$-0.43
ROE-45.7%
Debt/Equity0.17